{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T07:53:02Z","timestamp":1780732382759,"version":"3.54.1"},"reference-count":30,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,22]],"date-time":"2013-07-22T00:00:00Z","timestamp":1374451200000},"content-version":"vor","delay-in-days":202,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Jornal de Pediatria"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.jped.2013.02.006","type":"journal-article","created":{"date-parts":[[2013,3,28]],"date-time":"2013-03-28T05:30:51Z","timestamp":1364448651000},"page":"33-39","source":"Crossref","is-referenced-by-count":14,"title":["Comparison of Oral Ibuprofen and Intravenous Indomethacin for the Treatment of Patent Ductus Arteriosus in Extremely Low Birth Weight Infants"],"prefix":"10.1016","volume":"89","author":[{"given":"Eun Mi","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Song","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Youn","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jped.2013.02.006_bib0005","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1016\/S0735-1097(02)01886-7","article-title":"The incidence of congenital heart disease","volume":"39","author":"Hoffman","year":"2002","journal-title":"J Am Coll Cardiol."},{"key":"10.1016\/j.jped.2013.02.006_bib0010","doi-asserted-by":"crossref","unstructured":"The Vermont-Oxford Trials Network: very low birth weight outcomes for 1990. Investigators of the Vermont-Oxford Trials Network Database Project. Pediatrics. 1993;91:540-5.","DOI":"10.1542\/peds.91.3.540"},{"key":"10.1016\/j.jped.2013.02.006_bib0015","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1542\/peds.2005-1528","article-title":"Prevalence of spontaneous closure of the ductus arteriosus in neonates at a birth weight of 1000 grams or less","volume":"117","author":"Koch","year":"2006","journal-title":"Pediatrics."},{"key":"10.1016\/j.jped.2013.02.006_bib0020","doi-asserted-by":"crossref","first-page":"e287","DOI":"10.1542\/peds.2008-2232","article-title":"A second course of ibuprofen is effective in the closure of a clinically significant PDA in ELBW infants","volume":"124","author":"Richards","year":"2009","journal-title":"Pediatrics."},{"key":"10.1016\/j.jped.2013.02.006_bib0025","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1542\/peds.68.1.99","article-title":"Indomethacin and its effect on renal function and urinary kallikrein excretion in premature infants with patent ductus arteriosus","volume":"68","author":"Betkerur","year":"1981","journal-title":"Pediatrics."},{"key":"10.1016\/j.jped.2013.02.006_bib0030","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/S0022-3476(05)83391-8","article-title":"Indomethacin-induced changes in renal blood flow velocity waveform in premature infants investigated with color Doppler imaging","volume":"118","author":"van Bel","year":"1991","journal-title":"J Pediatr."},{"key":"10.1016\/j.jped.2013.02.006_bib0035","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1136\/adc.61.3.233","article-title":"Early administration of indomethacin to preterm infants","volume":"61","author":"Rennie","year":"1986","journal-title":"Arch Dis Child."},{"key":"10.1016\/j.jped.2013.02.006_bib0040","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/0140-6736(90)93030-S","article-title":"Effects of indomethacin on cerebral haemodynamics in very preterm infants","volume":"335","author":"Edwards","year":"1990","journal-title":"Lancet."},{"key":"10.1016\/j.jped.2013.02.006_bib0045","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1203\/00006450-199306000-00015","article-title":"Effect of indomethacin on cerebral oxidized cytochrome oxidase in preterm infants","volume":"33","author":"McCormick","year":"1993","journal-title":"Pediatr Res."},{"key":"10.1016\/j.jped.2013.02.006_bib0050","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1080\/08998280.2007.11928244","article-title":"Ibuprofen lysine (NeoProfen) for the treatment of patent ductus arteriosus","volume":"20","author":"Poon","year":"2007","journal-title":"Proc (Bayl Univ Med Cent)."},{"key":"10.1016\/j.jped.2013.02.006_bib0055","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1056\/NEJM200009073431001","article-title":"A comparison of ibuprofen and indomethacin for closure of patent ductus arteriosus","volume":"343","author":"Van Overmeire","year":"2000","journal-title":"N Engl J Med."},{"key":"10.1016\/j.jped.2013.02.006_bib0060","doi-asserted-by":"crossref","first-page":"S60","DOI":"10.1038\/jp.2008.52","article-title":"Treatment of patent ductus arteriosus: indomethacin or ibuprofen?","volume":"28","author":"Sekar","year":"2008","journal-title":"J Perinatol."},{"key":"10.1016\/j.jped.2013.02.006_bib0065","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1007\/s00431-002-0915-y","article-title":"Safety and efficacy of ibuprofen versus indomethacin in preterm infants treated for patent ductus arteriosus: a randomised controlled trial","volume":"161","author":"Lago","year":"2002","journal-title":"Eur J Pediatr."},{"key":"10.1016\/j.jped.2013.02.006_bib0070","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1053\/j.semperi.2006.04.003","article-title":"Systematic review: intravenous Ibuprofen in preterm newborns","volume":"30","author":"Aranda","year":"2006","journal-title":"Semin Perinatol."},{"key":"10.1016\/j.jped.2013.02.006_bib0075","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1111\/j.1442-200X.2003.01797.x","article-title":"Comparison of ibuprofen and indomethacin therapy for patent ductus arteriosus in preterm infants","volume":"45","author":"Su","year":"2003","journal-title":"Pediatr Int."},{"key":"10.1016\/j.jped.2013.02.006_bib0080","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0022-3476(78)80282-0","article-title":"Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm","volume":"92","author":"Papile","year":"1978","journal-title":"J Pediatr."},{"key":"10.1016\/j.jped.2013.02.006_bib0085","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1139\/y73-031","article-title":"The response of the ductus arteriosus to prostaglandins","volume":"51","author":"Coceani","year":"1973","journal-title":"Can J Physiol Pharmacol."},{"key":"10.1016\/j.jped.2013.02.006_bib0090","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1056\/NEJM197609022951003","article-title":"Pharmacologic closure of patent ductus arteriosus in the premature infant","volume":"295","author":"Friedman","year":"1976","journal-title":"N Engl J Med."},{"issue":"4","key":"10.1016\/j.jped.2013.02.006_bib0095","first-page":"CD003481","article-title":"Ibuprofen for the treatment of patent ductus arteriosus in preterm and\/or low birth weight infants","author":"Ohlsson","year":"2010","journal-title":"Cochrane Database Syst Rev."},{"key":"10.1016\/j.jped.2013.02.006_bib0100","first-page":"S563","article-title":"A comparison of oral ibuprofen and intravenous indomethacin for closure of patent ductus arteriosus in preterm infants","volume":"86","author":"Chotigeat","year":"2003","journal-title":"J Med Assoc Thai."},{"key":"10.1016\/j.jped.2013.02.006_bib0105","first-page":"399","article-title":"Comparison of oral ibuprofen and indomethacin therapy for patent ductus arteriosus in preterm infants","volume":"9","author":"Fakhraee","year":"2007","journal-title":"Zhongguo Dang Dai Er Ke Za Zhi."},{"key":"10.1016\/j.jped.2013.02.006_bib0110","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1055\/s-2007-976550","article-title":"Oral Ibuprofen and ductus arteriosus in premature infants: a randomized pilot study","volume":"24","author":"Aly","year":"2007","journal-title":"Am J Perinatol."},{"key":"10.1016\/j.jped.2013.02.006_bib0115","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.jpeds.2010.10.008","article-title":"Efficacy and safety of oral versus intravenous ibuprofen in very low birth weight preterm infants with patent ductus arteriosus","volume":"158","author":"Gokmen","year":"2011","journal-title":"J Pediatr."},{"key":"10.1016\/j.jped.2013.02.006_bib0120","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/j.jpeds.2011.12.031","article-title":"Timing of patent ductus arteriosus treatment and respiratory outcome in premature infants: a double-blind randomized controlled trial","volume":"160","author":"Sosenko","year":"2012","journal-title":"J Pediatr."},{"key":"10.1016\/j.jped.2013.02.006_bib0125","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/sj.jp.7200296","article-title":"Ibuprofen use to reduce the incidence and severity of bronchopulmonary dysplasia: a pilot study","volume":"20","author":"Raju","year":"2000","journal-title":"J Perinatol."},{"key":"10.1016\/j.jped.2013.02.006_bib0130","doi-asserted-by":"crossref","first-page":"F116","DOI":"10.1136\/adc.2011.215160","article-title":"Pharmacokinetics of oral ibuprofen for patent ductus arteriosus closure in preterm infants","volume":"97","author":"Barzilay","year":"2012","journal-title":"Arch Dis Child Fetal Neonatal Ed."},{"key":"10.1016\/j.jped.2013.02.006_bib0135","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1177\/0091270003254635","article-title":"Pharmacokinetics of oral ibuprofen in premature infants","volume":"43","author":"Sharma","year":"2003","journal-title":"J Clin Pharmacol."},{"key":"10.1016\/j.jped.2013.02.006_bib0140","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1067\/mcp.2001.118453","article-title":"Ibuprofen pharmacokinetics in preterm infants with patent ductus arteriosus","volume":"70","author":"Van Overmeire","year":"2001","journal-title":"Clin Pharmacol Ther."},{"key":"10.1016\/j.jped.2013.02.006_bib0145","first-page":"179","article-title":"Biochemistry of prostaglandin endoperoxide H synthase-1 and synthase-2 and their differential susceptibility to nonsteroidal anti-inflammatory drugs","volume":"15","author":"Smith","year":"1995","journal-title":"Semin Nephrol."},{"key":"10.1016\/j.jped.2013.02.006_bib0150","unstructured":"Vane JR, Botting RM. Mechanism of action of anti-inflammatory drugs. In: Sinzinger H, Samuelsson B, Vane JR, Paoletti R, Ramwell P, Wong PY-K, editors. Recent advances in prostaglandin, thromboxane, and leukotriene research. Vol. 433 of Advances in experimental medicine and biology. New York: Plenum Press; 1997. p. 137-8."}],"container-title":["Jornal de Pediatria"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021755713000077?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021755713000077?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,2,12]],"date-time":"2022-02-12T15:25:35Z","timestamp":1644679535000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021755713000077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S0021755713000077"],"URL":"https:\/\/doi.org\/10.1016\/j.jped.2013.02.006","relation":{},"ISSN":["0021-7557"],"issn-type":[{"value":"0021-7557","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}