{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T22:05:36Z","timestamp":1789423536542,"version":"build-2803163510"},"reference-count":30,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,11,3]],"date-time":"2016-11-03T00:00:00Z","timestamp":1478131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Jornal de Pediatria"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.jped.2016.12.003","type":"journal-article","created":{"date-parts":[[2017,2,23]],"date-time":"2017-02-23T14:00:18Z","timestamp":1487858418000},"page":"460-466","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Early amplitude-integrated electroencephalography for monitoring neonates at high risk for brain injury"],"prefix":"10.1016","volume":"93","author":[{"given":"Gabriel Fernando Todeschi","family":"Variane","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maur\u00edcio","family":"Magalh\u00e3es","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato","family":"Gasperine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heitor Castelo Branco Rodrigues","family":"Alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thiago Luiz Pereira Donoso","family":"Scoppetta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo de Jesus Gon\u00e7alves","family":"Figueredo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Paulo Martins","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Netto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo Jenne","family":"Mimica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clery Bernardi","family":"Gallacci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jped.2016.12.003_bib0155","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/pr.2013.204","article-title":"Preterm birth-associated neurodevelopmental impairment estimates at regional and global levels for 2010","volume":"74","author":"Blencowe","year":"2013","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jped.2016.12.003_bib0160","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/pr.2013.206","article-title":"Intrapartum-related neonatal encephalopathy incidence and impairment at regional and global levels for 2010 with trends from 1990","volume":"74","author":"Lee","year":"2013","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jped.2016.12.003_bib0165","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.earlhumdev.2008.11.010","article-title":"Brain imaging findings in very preterm infants throughout the neonatal period: part I. Incidences and evolution of lesions, comparison between ultrasound and MRI","volume":"85","author":"Leijser","year":"2009","journal-title":"Early Hum Dev"},{"key":"10.1016\/j.jped.2016.12.003_bib0170","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0022-3476(82)80462-9","article-title":"Sonographic classification of intracranial hemorrhage. A prognostic indicator of mortality, morbidity, and short-term neurologic outcome","volume":"100","author":"Shankaran","year":"1982","journal-title":"J Pediatr"},{"key":"10.1016\/j.jped.2016.12.003_bib0175","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0387-7604(99)00034-0","article-title":"Neonatal EEG: a powerful tool in the assessment of brain damage in preterm infants","volume":"21","author":"Watanabe","year":"1999","journal-title":"Brain Dev"},{"key":"10.1016\/j.jped.2016.12.003_bib0180","doi-asserted-by":"crossref","first-page":"F106","DOI":"10.1136\/adc.2010.204735","article-title":"Prognostic value of EEG in very premature newborns","volume":"97","author":"Le Bihannic","year":"2012","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.jped.2016.12.003_bib0185","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1111\/j.1469-8749.2002.tb00278.x","article-title":"Developmental outcome and types of chronic-stage EEG abnormalities in preterm infants","volume":"44","author":"Okumura","year":"2002","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.jped.2016.12.003_bib0190","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1203\/PDR.0b013e3181d4ecda","article-title":"Decreased aEEG continuity and baseline variability in the first 48hours of life associated with poor short-term outcome in neonates born before 29 weeks gestation","volume":"67","author":"Bowen","year":"2010","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jped.2016.12.003_bib0195","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.pediatrneurol.2010.11.018","article-title":"Low-voltage aEEG as predictor of intracranial hemorrhage in preterm infants","volume":"44","author":"Chalak","year":"2011","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.jped.2016.12.003_bib0200","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.ejpn.2012.02.008","article-title":"Early abnormal amplitude-integrated electroencephalography (aEEG) is associated with adverse short-term outcome in premature infants","volume":"16","author":"Soubasi","year":"2012","journal-title":"Eur J Paediatr Neurol"},{"key":"10.1016\/j.jped.2016.12.003_bib0205","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jped.2013.07.004","article-title":"Clinical utility of early amplitude integrated EEG in monitoring term newborns at risk of neurological injury","volume":"90","author":"Toso","year":"2014","journal-title":"J Pediatr (Rio J)"},{"key":"10.1016\/j.jped.2016.12.003_bib0210","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1542\/peds.103.6.1263","article-title":"Assessment of neonatal encephalopathy by amplitude-integrated electroencephalography","volume":"103","author":"al Naqeeb","year":"1999","journal-title":"Pediatrics"},{"key":"10.1016\/j.jped.2016.12.003_bib0215","doi-asserted-by":"crossref","first-page":"F19","DOI":"10.1136\/fn.81.1.F19","article-title":"Amplitude integrated EEG 3 and 6hours after birth in full term neonates with hypoxic-ischaemic encephalopathy","volume":"81","author":"Toet","year":"1999","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.jped.2016.12.003_bib0220","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1203\/PDR.0b013e31821ba200","article-title":"Amplitude-integrated EEG pattern predicts further outcome in preterm infants","volume":"70","author":"Klebermass","year":"2011","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jped.2016.12.003_bib0225","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1111\/j.1651-2227.2012.02677.x","article-title":"Early single-channel aEEG\/EEG predicts outcome in very preterm infants","volume":"101","author":"Wikstr\u00f6m","year":"2012","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.jped.2016.12.003_bib0230","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1001\/archneur.1976.00500100030012","article-title":"Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study","volume":"33","author":"Sarnat","year":"1976","journal-title":"Arch Neurol"},{"key":"10.1016\/j.jped.2016.12.003_bib0235","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.siny.2006.07.011","article-title":"Continuous brain-function monitoring: state of the art in clinical practice","volume":"11","author":"Hellstr\u00f6m-Westas","year":"2006","journal-title":"Semin Fetal Neonatal Med"},{"key":"10.1016\/j.jped.2016.12.003_bib0240","doi-asserted-by":"crossref","first-page":"e61","DOI":"10.1542\/peds.113.1.e61","article-title":"Reference values for amplitude-integrated electroencephalographic activity in preterm infants younger than 30 weeks\u2019 gestational age","volume":"113","author":"Olischar","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.jped.2016.12.003_bib0245","doi-asserted-by":"crossref","first-page":"S42","DOI":"10.1111\/j.1528-1157.1999.tb00878.x","article-title":"Acute and chronic effects of seizures in the developing brain: lessons from clinical experience","volume":"40","author":"Mizrahi","year":"1999","journal-title":"Epilepsia"},{"key":"10.1016\/j.jped.2016.12.003_bib0250","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S1474-4422(09)70295-9","article-title":"Assessment of brain tissue injury after moderate hypothermia in neonates with hypoxic-ischaemic encephalopathy: a nested substudy of a randomised controlled trial","volume":"9","author":"Rutherford","year":"2010","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.jped.2016.12.003_bib0255","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1159\/000345202","article-title":"Delayed cyclic activity development on early amplitude-integrated EEG in the preterm infant with brain lesions","volume":"103","author":"Natalucci","year":"2013","journal-title":"Neonatology"},{"key":"10.1016\/j.jped.2016.12.003_bib0260","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1055\/s-0034-1382823","article-title":"Predictive value of early amplitude-integrated electroencephalography for later diagnosed cerebral white matter damage in preterm infants","volume":"45","author":"Song","year":"2014","journal-title":"Neuropediatrics"},{"key":"10.1016\/j.jped.2016.12.003_bib0265","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s00431-014-2360-0","article-title":"Low-voltage pattern and absence of sleep-wake cycles are associated with severe hemorrhage and death in very preterm infants","volume":"174","author":"Benavente-Fern\u00e1ndez","year":"2015","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.jped.2016.12.003_bib0270","doi-asserted-by":"crossref","first-page":"F219","DOI":"10.1136\/archdischild-2013-305206","article-title":"Electrographic seizures are associated with brain injury in newborns undergoing therapeutic hypothermia","volume":"99","author":"Shah","year":"2014","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.jped.2016.12.003_bib0275","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.jpeds.2011.07.015","article-title":"Seizures and magnetic resonance imaging-detected brain injury in newborns cooled for hypoxic-ischemic encephalopathy","volume":"159","author":"Glass","year":"2011","journal-title":"J Pediatr"},{"key":"10.1016\/j.jped.2016.12.003_bib0280","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1159\/000339570","article-title":"aEEG evolution during therapeutic hypothermia and prediction of NICU outcome in encephalopathic neonates","volume":"102","author":"Massaro","year":"2012","journal-title":"Neonatology"},{"key":"10.1016\/j.jped.2016.12.003_bib0285","doi-asserted-by":"crossref","first-page":"e131","DOI":"10.1542\/peds.2009-2938","article-title":"Effect of hypothermia on amplitude-integrated electroencephalogram in infants with asphyxia","volume":"126","author":"Thoresen","year":"2010","journal-title":"Pediatrics"},{"key":"10.1016\/j.jped.2016.12.003_bib0290","first-page":"115","article-title":"Meta-analysis of prognostic tests in neonates over 35-week gestational age with hypoxic-ischemic encephalopathy","volume":"94","author":"Lin","year":"2014","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"10.1016\/j.jped.2016.12.003_bib0295","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.1440-1754.2007.01270.x","article-title":"Single versus bihemispheric amplitude-integrated electroencephalography in relation to cerebral injury and outcome in the term encephalopathic infant","volume":"44","author":"Lavery","year":"2008","journal-title":"J Paediatr Child Health"},{"key":"10.1016\/j.jped.2016.12.003_bib0300","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.seizure.2013.05.006","article-title":"Acute neonatal encephalopathy and seizures recurrence: a combined aEEG\/EEG study","volume":"22","author":"Mastrangelo","year":"2013","journal-title":"Seizure"}],"container-title":["Jornal de Pediatria"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021755716302595?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021755716302595?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,3]],"date-time":"2018-09-03T23:22:08Z","timestamp":1536016928000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021755716302595"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["S0021755716302595"],"URL":"https:\/\/doi.org\/10.1016\/j.jped.2016.12.003","relation":{},"ISSN":["0021-7557"],"issn-type":[{"value":"0021-7557","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early amplitude-integrated electroencephalography for monitoring neonates at high risk for brain injury","name":"articletitle","label":"Article Title"},{"value":"Jornal de Pediatria","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jped.2016.12.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier Editora Ltda. on behalf of Sociedade Brasileira de Pediatria.","name":"copyright","label":"Copyright"}]}}