{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T03:16:02Z","timestamp":1785208562213,"version":"3.55.0"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,5,10]],"date-time":"2017-05-10T00:00:00Z","timestamp":1494374400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Jornal de Pediatria"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.jped.2017.06.006","type":"journal-article","created":{"date-parts":[[2017,8,15]],"date-time":"2017-08-15T03:15:28Z","timestamp":1502766928000},"page":"36-45","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":53,"special_numbering":"S1","title":["The use of high-flow nasal cannula in the pediatric emergency department"],"prefix":"10.1016","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3325-3202","authenticated-orcid":false,"given":"Katherine N.","family":"Slain","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven L.","family":"Shein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre T.","family":"Rotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jped.2017.06.006_bib0235","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s00134-012-2743-5","article-title":"Use of high flow nasal cannula in critically ill infants, children, and adults: a critical review of the literature","volume":"39","author":"Lee","year":"2013","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jped.2017.06.006_bib0240","first-page":"CD009609","article-title":"High-flow nasal cannula therapy for infants with bronchiolitis","author":"Beggs","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jped.2017.06.006_bib0245","first-page":"CD009850","article-title":"High-flow nasal cannula therapy for respiratory support in children","author":"Mayfield","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jped.2017.06.006_bib0250","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/S0140-6736(17)30061-2","article-title":"High-flow warm humidified oxygen versus standard low-flow nasal cannula oxygen for moderate bronchiolitis (HFWHO RCT): an open, phase 4, randomised controlled trial","volume":"389","author":"Kepreotes","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.jped.2017.06.006_bib0255","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1056\/NEJMoa1503326","article-title":"High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure","volume":"372","author":"Frat","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jped.2017.06.006_bib0260","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1542\/peds.2015-0738","article-title":"Safety and efficacy of high-flow nasal cannula therapy in preterm infants: a meta-analysis","volume":"136","author":"Kotecha","year":"2015","journal-title":"Pediatrics"},{"key":"10.1016\/j.jped.2017.06.006_bib0265","doi-asserted-by":"crossref","first-page":"98","DOI":"10.4187\/respcare.01941","article-title":"High-flow oxygen administration by nasal cannula for adult and perinatal patients","volume":"58","author":"Ward","year":"2013","journal-title":"Respir Care"},{"key":"10.1016\/j.jped.2017.06.006_bib0270","first-page":"707","article-title":"AARC Clinical Practice Guideline: selection of an oxygen delivery device for neonatal and pediatric patients \u2013 2002 revision & update","volume":"47","author":"Myers","year":"2002","journal-title":"Respir Care"},{"key":"10.1016\/j.jped.2017.06.006_bib0275","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1164\/ajrccm\/142.6_Pt_1.1288","article-title":"Nasal and oral flow-volume loops in normal subjects and patients with obstructive sleep apnea","volume":"142","author":"Shepard","year":"1990","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.jped.2017.06.006_bib0280","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1016\/j.rmed.2009.04.007","article-title":"Research in high flow therapy: mechanisms of action","volume":"103","author":"Dysart","year":"2009","journal-title":"Respir Med"},{"key":"10.1016\/j.jped.2017.06.006_bib0285","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1152\/jappl.1996.80.5.1485","article-title":"Anatomic dead space in infants and children","volume":"80","author":"Numa","year":"1996","journal-title":"J Appl Physiol (1985)"},{"key":"10.1016\/j.jped.2017.06.006_bib0290","first-page":"408","article-title":"High-flow oxygen therapy in acute respiratory failure","volume":"55","author":"Roca","year":"2010","journal-title":"Respir Care"},{"key":"10.1016\/j.jped.2017.06.006_bib0295","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.rmed.2009.12.016","article-title":"The clinical utility of long-term humidification therapy in chronic airway disease","volume":"104","author":"Rea","year":"2010","journal-title":"Respir Med"},{"key":"10.1016\/j.jped.2017.06.006_bib0300","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1177\/1479972307087190","article-title":"Domiciliary humidification improves lung mucociliary clearance in patients with bronchiectasis","volume":"5","author":"Hasani","year":"2008","journal-title":"Chron Respir Dis"},{"key":"10.1016\/j.jped.2017.06.006_bib0305","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1007\/s00134-013-2879-y","article-title":"Is treatment with a high flow nasal cannula effective in acute viral bronchiolitis? A physiologic study","volume":"39","author":"Milesi","year":"2013","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jped.2017.06.006_bib0310","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1097\/PEC.0b013e318271a671","article-title":"Nasopharyngeal airway pressures in bronchiolitis patients treated with high-flow nasal cannula oxygen therapy","volume":"28","author":"Arora","year":"2012","journal-title":"Pediatr Emerg Care"},{"key":"10.1016\/j.jped.2017.06.006_bib0315","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1177\/0885066609340622","article-title":"Children with respiratory distress treated with high-flow nasal cannula","volume":"24","author":"Spentzas","year":"2009","journal-title":"J Intensive Care Med"},{"key":"10.1016\/j.jped.2017.06.006_bib0320","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/PCC.0000000000000011","article-title":"Effort of breathing in children receiving high-flow nasal cannula","volume":"15","author":"Rubin","year":"2014","journal-title":"Pediatr Crit Care Med"},{"key":"10.1016\/j.jped.2017.06.006_bib0325","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1002\/ppul.23060","article-title":"The effect of high flow nasal cannula therapy on the work of breathing in infants with bronchiolitis","volume":"50","author":"Pham","year":"2015","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.jped.2017.06.006_bib0330","doi-asserted-by":"crossref","first-page":"e214","DOI":"10.1097\/PCC.0000000000000112","article-title":"Physiologic effect of high-flow nasal cannula in infants with bronchiolitis","volume":"15","author":"Hough","year":"2014","journal-title":"Pediatr Crit Care Med"},{"key":"10.1016\/j.jped.2017.06.006_bib0335","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1542\/hpeds.2014-0220","article-title":"Effect of a hospital-wide high-flow nasal cannula protocol on clinical outcomes and resource utilization of bronchiolitis patients admitted to the PICU","volume":"5","author":"Riese","year":"2015","journal-title":"Hosp Pediatr"},{"key":"10.1016\/j.jped.2017.06.006_bib0340","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1007\/s00431-014-2275-9","article-title":"Comparison of a high-flow humidified nasal cannula to nasal continuous positive airway pressure in children with acute bronchiolitis: experience in a pediatric intensive care unit","volume":"173","author":"Metge","year":"2014","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.jped.2017.06.006_bib0345","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1111\/jpc.12509","article-title":"High-flow nasal cannula oxygen therapy for infants with bronchiolitis: pilot study","volume":"50","author":"Mayfield","year":"2014","journal-title":"J Paediatr Child Health"},{"key":"10.1016\/j.jped.2017.06.006_bib0350","first-page":"A6347","article-title":"High-flow nasal cannula offers greater reduction of effort of breathing in children of lower weight","volume":"193","author":"Weiler","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jped.2017.06.006_bib0355","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1097\/PEC.0b013e31827122a9","article-title":"Use of high-flow nasal cannula support in the emergency department reduces the need for intubation in pediatric acute respiratory insufficiency","volume":"28","author":"Wing","year":"2012","journal-title":"Pediatr Emerg Care"},{"key":"10.1016\/j.jped.2017.06.006_bib0360","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1097\/PEC.0b013e31829e7f2f","article-title":"High-flow nasal cannula use in children with respiratory distress in the emergency department: predicting the need for subsequent intubation","volume":"29","author":"Kelly","year":"2013","journal-title":"Pediatr Emerg Care"},{"key":"10.1016\/j.jped.2017.06.006_bib0365","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1007\/s00134-011-2177-5","article-title":"Reduced intubation rates for infants after introduction of high-flow nasal prong oxygen delivery","volume":"37","author":"Schibler","year":"2011","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jped.2017.06.006_bib0370","doi-asserted-by":"crossref","first-page":"e326","DOI":"10.1097\/PCC.0b013e31828a894d","article-title":"High-flow nasal prong oxygen therapy or nasopharyngeal continuous positive airway pressure for children with moderate-to-severe respiratory distress?","volume":"14","author":"ten Brink","year":"2013","journal-title":"Pediatr Crit Care Med"},{"key":"10.1016\/j.jped.2017.06.006_bib0375","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/s13049-016-0278-4","article-title":"High flow nasal cannula in children: a literature review","volume":"24","author":"Mikalsen","year":"2016","journal-title":"Scand J Trauma Resusc Emerg Med"},{"key":"10.1016\/j.jped.2017.06.006_bib0380","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.jpeds.2009.10.039","article-title":"High flow nasal cannulae therapy in infants with bronchiolitis","volume":"156","author":"McKiernan","year":"2010","journal-title":"J Pediatr"},{"key":"10.1016\/j.jped.2017.06.006_bib0385","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1097\/PCC.0000000000000985","article-title":"The clinical impact of heated humidified high-flow nasal cannula on pediatric respiratory distress","volume":"18","author":"Kawaguchi","year":"2017","journal-title":"Pediatr Crit Care Med"},{"key":"10.1016\/j.jped.2017.06.006_bib0390","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s00134-016-4617-8","article-title":"High flow nasal cannula (HFNC) versus nasal continuous positive airway pressure (nCPAP) for the initial respiratory management of acute viral bronchiolitis in young infants: a multicenter randomized controlled trial (TRAMONTANE study)","volume":"43","author":"Milesi","year":"2017","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jped.2017.06.006_bib0395","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/S0140-6736(15)60249-5","article-title":"Bubble continuous positive airway pressure for children with severe pneumonia and hypoxaemia in Bangladesh: an open, randomised controlled trial","volume":"386","author":"Chisti","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.jped.2017.06.006_bib0400","doi-asserted-by":"crossref","first-page":"e343","DOI":"10.1097\/PCC.0b013e31825b546f","article-title":"Predictors of failure in infants with viral bronchiolitis treated with high-flow, high-humidity nasal cannula therapy","volume":"13","author":"Abboud","year":"2012","journal-title":"Pediatr Crit Care Med"},{"key":"10.1016\/j.jped.2017.06.006_bib0405","doi-asserted-by":"crossref","first-page":"e368","DOI":"10.1111\/apa.13444","article-title":"Using a high-flow nasal cannula provided superior results to low-flow oxygen delivery in moderate to severe bronchiolitis","volume":"105","author":"Milani","year":"2016","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.jped.2017.06.006_bib0410","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1093\/icvts\/ivu171","article-title":"Comparative evaluation of high-flow nasal cannula and conventional oxygen therapy in paediatric cardiac surgical patients: a randomized controlled trial","volume":"19","author":"Testa","year":"2014","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"10.1016\/j.jped.2017.06.006_bib0415","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1136\/archdischild-2011-301151","article-title":"Pilot study of vapotherm oxygen delivery in moderately severe bronchiolitis","volume":"97","author":"Hilliard","year":"2012","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jped.2017.06.006_bib0420","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1542\/peds.2012-3877","article-title":"Trends in bronchiolitis hospitalizations in the United States, 2000\u20132009","volume":"132","author":"Hasegawa","year":"2013","journal-title":"Pediatrics"},{"key":"10.1016\/j.jped.2017.06.006_bib0425","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1007\/s00431-013-2094-4","article-title":"High-flow nasal cannula oxygen for bronchiolitis in a pediatric ward: a pilot study","volume":"172","author":"Bressan","year":"2013","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.jped.2017.06.006_bib0430","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1136\/archdischild-2014-306637","article-title":"Use of high flow nasal cannula oxygen (HFNCO) in infants with bronchiolitis on a paediatric ward: a 3-year experience","volume":"99","author":"Kallappa","year":"2014","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jped.2017.06.006_bib0435","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1111\/1742-6723.12741","article-title":"Paediatric high-flow nasal cannula therapy in children with bronchiolitis: a retrospective safety and efficacy study in a non-tertiary environment","volume":"29","author":"Davison","year":"2017","journal-title":"Emerg Med Australas"},{"key":"10.1016\/j.jped.2017.06.006_bib0440","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1038\/jp.2008.99","article-title":"Subcutaneous scalp emphysema, pneumo-orbitis and pneumocephalus in a neonate on high humidity high flow nasal cannula","volume":"28","author":"Jasin","year":"2008","journal-title":"J Perinatol"},{"key":"10.1016\/j.jped.2017.06.006_bib0445","doi-asserted-by":"crossref","first-page":"e939","DOI":"10.1542\/peds.2011-3767","article-title":"Serious air leak syndrome complicating high-flow nasal cannula therapy: a report of 3 cases","volume":"131","author":"Hegde","year":"2013","journal-title":"Pediatrics"},{"key":"10.1016\/j.jped.2017.06.006_bib0450","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1542\/hpeds.2016-0194","article-title":"Nutrition and high-flow nasal cannula respiratory support in children with bronchiolitis","volume":"7","author":"Slain","year":"2017","journal-title":"Hosp Pediatr"},{"key":"10.1016\/j.jped.2017.06.006_bib0455","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1542\/hpeds.2016-0131","article-title":"Oral nutrition in children with bronchiolitis on high-flow nasal cannula is well tolerated","volume":"7","author":"Sochet","year":"2017","journal-title":"Hosp Pediatr"},{"key":"10.1016\/j.jped.2017.06.006_bib0460","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1186\/s12887-015-0501-x","article-title":"Early high flow nasal cannula therapy in bronchiolitis, a prospective randomised control trial (protocol): a Paediatric Acute Respiratory Intervention Study (PARIS)","volume":"15","author":"Franklin","year":"2015","journal-title":"BMC Pediatr"}],"container-title":["Jornal de Pediatria"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021755717304473?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021755717304473?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T01:42:20Z","timestamp":1659318140000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021755717304473"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":46,"alternative-id":["S0021755717304473"],"URL":"https:\/\/doi.org\/10.1016\/j.jped.2017.06.006","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.729271909.793538107","asserted-by":"object"}]},"ISSN":["0021-7557"],"issn-type":[{"value":"0021-7557","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The use of high-flow nasal cannula in the pediatric emergency department","name":"articletitle","label":"Article Title"},{"value":"Jornal de Pediatria","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jped.2017.06.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda.","name":"copyright","label":"Copyright"}]}}