{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T16:31:41Z","timestamp":1762187501684,"version":"build-2065373602"},"reference-count":32,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,10,12]],"date-time":"2018-10-12T00:00:00Z","timestamp":1539302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006417","name":"Fundo de Apoio ao Ensino, \u00c3\u00a0 Pesquisa e Extens\u00c3\u00a3o, Universidade Estadual de Campinas","doi-asserted-by":"publisher","award":["149\/09"],"award-info":[{"award-number":["149\/09"]}],"id":[{"id":"10.13039\/501100006417","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Jornal de Pediatria"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.jped.2018.09.001","type":"journal-article","created":{"date-parts":[[2018,10,22]],"date-time":"2018-10-22T10:26:35Z","timestamp":1540203995000},"page":"210-216","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Refractory functional constipation: clinical management or appendicostomy?"],"prefix":"10.1016","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6850-9012","authenticated-orcid":false,"given":"Vanesca P.A. de","family":"Arruda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1145-2606","authenticated-orcid":false,"given":"Maria A.","family":"Bellomo-Brand\u00e3o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2441-0808","authenticated-orcid":false,"given":"Joaquim M.","family":"Bustorff-Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5504-4746","authenticated-orcid":false,"given":"Elizete Aparecida","family":"Lomazi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jped.2018.09.001_bib0165","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1111\/j.1365-2982.2009.01399.x","article-title":"Chronic constipation: overview and challenges","volume":"21","author":"Cook","year":"2009","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.jped.2018.09.001_bib0170","first-page":"147","article-title":"Constipa\u00e7\u00e3o intestinal","volume":"76","author":"de Morais","year":"2000","journal-title":"J Pediatr (Rio J)"},{"key":"10.1016\/j.jped.2018.09.001_bib0175","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1097\/MPG.0b013e3181afcdc3","article-title":"Functional constipation in children: a systematic review on prognosis and predictive factors","volume":"50","author":"Pijpers","year":"2010","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jped.2018.09.001_bib0180","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1097\/MPG.0000000000000266","article-title":"Evaluation and treatment of functional constipation in infants and children: evidence-based recommendations from ESPGHAN and NASPGHAN","volume":"58","author":"Tabbers","year":"2014","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jped.2018.09.001_bib0185","doi-asserted-by":"crossref","first-page":"e156","DOI":"10.1542\/peds.2009-1009","article-title":"Long-term prognosis for childhood constipation: clinical outcomes in adulthood","volume":"126","author":"Bongers","year":"2010","journal-title":"Pediatrics"},{"key":"10.1016\/j.jped.2018.09.001_bib0190","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1097\/01.mpg.0000167500.34236.6a","article-title":"Chronic childhood constipation is associated with impaired quality of life: a case-controlled study","volume":"41","author":"Youssef","year":"2005","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jped.2018.09.001_bib0195","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1016\/j.jpedsurg.2005.08.011","article-title":"The antegrade continence enema successfully treats idiopathic slow-transit constipation","volume":"40","author":"King","year":"2005","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jped.2018.09.001_bib0200","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/0140-6736(90)92834-5","article-title":"Preliminary report: the antegrade continence enema","volume":"336","author":"Malone","year":"1990","journal-title":"Lancet"},{"key":"10.1016\/j.jped.2018.09.001_bib0205","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/nmo.12018","article-title":"Factors associated with successful decrease and discontinuation of antegrade continence enemas (ACE) in children with defecation disorders: a study evaluating the effect of ACE on colon motility","volume":"25","author":"Rodriguez","year":"2013","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.jped.2018.09.001_bib0210","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1097\/SLA.0000000000001191","article-title":"Current surgical management of pediatric idiopathic constipation: a systematic review of published studies","volume":"262","author":"Siminas","year":"2015","journal-title":"Ann Surg"},{"key":"10.1016\/j.jped.2018.09.001_bib0215","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1053\/j.gastro.2005.11.065","article-title":"Childhood functional gastrointestinal disorders: neonate\/toddler","volume":"130","author":"Hyman","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jped.2018.09.001_bib0220","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1053\/j.gastro.2005.08.063","article-title":"Childhood functional gastrointestinal disorders: child\/adolescent","volume":"130","author":"Rasquin","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jped.2018.09.001_bib0225","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.jped.2014.10.007","article-title":"Colonic transit in children and adolescents with chronic constipation","volume":"91","author":"Carmo","year":"2015","journal-title":"J Pediatr (Rio J)"},{"key":"10.1016\/j.jped.2018.09.001_bib0230","first-page":"71","article-title":"Targeting the causes of intractable chronic constipation in children: the Nuclear Transit Study (NTS)","volume":"22","author":"Yik","year":"2010","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.jped.2018.09.001_bib0235","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1097\/01.ju.0000138528.55602.20","article-title":"In situ Malone antegrade continence enema in 127 patients: a 6-year experience","volume":"172","author":"Herndon","year":"2004","journal-title":"J Urol"},{"key":"10.1016\/j.jped.2018.09.001_bib0240","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s00383-009-2363-5","article-title":"Slow-transit constipation in children: our experience","volume":"25","author":"Hutson","year":"2009","journal-title":"Pediatr Surg Int"},{"key":"10.1016\/j.jped.2018.09.001_bib0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1440-1754.2005.00527.x","article-title":"Chronic constipation in children: organic disorders are a major cause","volume":"41","author":"Southwell","year":"2005","journal-title":"J Paediatr Child Health"},{"key":"10.1016\/j.jped.2018.09.001_bib0250","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1097\/MPG.0000000000000255","article-title":"Chronic functional constipation in children: adherence and factors associated with drug treatment","volume":"58","author":"Steiner","year":"2014","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jped.2018.09.001_bib0255","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1007\/s00383-014-3602-y","article-title":"Antegrade continence enema (ACE): predictors of outcome in 111 patients","volume":"30","author":"Basson","year":"2014","journal-title":"Pediatr Surg Int"},{"key":"10.1016\/j.jped.2018.09.001_bib0260","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1097\/MPG.0b013e3181ff6042","article-title":"Long-term follow-up of patients after antegrade continence enema procedure","volume":"52","author":"Siddiqui","year":"2011","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jped.2018.09.001_bib0265","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.jpedsurg.2016.10.022","article-title":"Contemporary short- and long-term outcomes in patients with unremitting constipation and fecal incontinence treated with an antegrade continence enema","volume":"52","author":"Dolejs","year":"2017","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jped.2018.09.001_bib0270","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/j.jpeds.2012.04.042","article-title":"Ten-year experience using antegrade enemas in children","volume":"161","author":"Mugie","year":"2012","journal-title":"J Pediatr"},{"key":"10.1016\/j.jped.2018.09.001_bib0275","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/j.jpedsurg.2005.12.018","article-title":"Colonic manometry as predictor of cecostomy success in children with defecation disorders","volume":"41","author":"van den Berg","year":"2006","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jped.2018.09.001_bib0280","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1016\/j.jpedsurg.2009.02.030","article-title":"After the honeymoon comes divorce: long-term use of the antegrade continence enema procedure","volume":"44","author":"Yardley","year":"2009","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jped.2018.09.001_bib0285","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/S0022-3468(98)90381-5","article-title":"How to achieve a successful Malone antegrade continence enema","volume":"33","author":"Curry","year":"1998","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jped.2018.09.001_bib0290","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1007\/s00383-004-1220-9","article-title":"MACE or caecostomy button for idiopathic constipation in children: a comparison of complications and outcomes","volume":"20","author":"Cascio","year":"2004","journal-title":"Pediatr Surg Int"},{"key":"10.1016\/j.jped.2018.09.001_bib0295","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1053\/jpsu.2002.36719","article-title":"Avoidance of leakage and strictures when creating an invisible conduit for antegrade colonic enemas","volume":"37","author":"Shaul","year":"2002","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jped.2018.09.001_bib0300","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/j.juro.2008.05.062","article-title":"The Malone antegrade continence enema: single institutional review","volume":"180","author":"Bani-Hani","year":"2008","journal-title":"J Urol"},{"key":"10.1016\/j.jped.2018.09.001_bib0305","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S1072-7515(98)00189-6","article-title":"Simplified technique for antegrade continence enemas for fecal retention and incontinence","volume":"187","author":"Fonkalsrud","year":"1998","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.jped.2018.09.001_bib0310","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1148\/radiology.203.3.9169678","article-title":"Fecal incontinence in children: treatment with percutaneous cecostomy tube placement \u2013 a prospective study","volume":"203","author":"Chait","year":"1997","journal-title":"Radiology"},{"key":"10.1016\/j.jped.2018.09.001_bib0315","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.jpedsurg.2018.02.010","article-title":"Malone appendicostomy versus cecostomy tube insertion for children with intractable constipation: a systematic review and meta-analysis","volume":"53","author":"Li","year":"2018","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jped.2018.09.001_bib0320","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1016\/j.jpedsurg.2013.01.045","article-title":"Quality of life in pediatric patients with unremitting constipation pre and post Malone Antegrade Continence Enema (MACE) procedure","volume":"48","author":"Har","year":"2013","journal-title":"J Pediatr Surg"}],"container-title":["Jornal de Pediatria"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021755718306053?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021755718306053?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T16:04:06Z","timestamp":1762185846000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021755718306053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["S0021755718306053"],"URL":"https:\/\/doi.org\/10.1016\/j.jped.2018.09.001","relation":{},"ISSN":["0021-7557"],"issn-type":[{"type":"print","value":"0021-7557"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Refractory functional constipation: clinical management or appendicostomy?","name":"articletitle","label":"Article Title"},{"value":"Jornal de Pediatria","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jped.2018.09.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda.","name":"copyright","label":"Copyright"}]}}