{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T04:03:03Z","timestamp":1773288183684,"version":"3.50.1"},"reference-count":42,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2007,10,1]],"date-time":"2007-10-01T00:00:00Z","timestamp":1191196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2007,10]]},"DOI":"10.1016\/j.jpeds.2007.04.070","type":"journal-article","created":{"date-parts":[[2007,8,8]],"date-time":"2007-08-08T07:20:09Z","timestamp":1186557609000},"page":"359-363","source":"Crossref","is-referenced-by-count":47,"title":["IgE Food Sensitization in Infants with Eczema Attending a Dermatology Department"],"prefix":"10.1016","volume":"151","author":[{"given":"David J.","family":"Hill","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralf G.","family":"Heine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cliff S.","family":"Hosking","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leone","family":"Thiele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrina J.","family":"Allen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Su","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Varigos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John B.","family":"Carlin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2007.04.070_bib1","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1172\/JCI21060","article-title":"New insights into atopic dermatitis","volume":"113","author":"Leung","year":"2004","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jpeds.2007.04.070_bib2","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1399-3038.2004.00178.x","article-title":"Food allergy and atopic dermatitis in infancy: an epidemiologic study","volume":"15","author":"Hill","year":"2004","journal-title":"Pediatr Allergy Immunol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib3","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/j.jaci.2004.01.778","article-title":"The natural course of atopic dermatitis from birth to age 7 years and the association with asthma","volume":"113","author":"Illi","year":"2004","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib4","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1111\/j.1365-2133.2003.05605.x","article-title":"A prospective study of the prevalence and incidence of atopic dermatitis in children aged 0-42 months","volume":"149","author":"Wadonda-Kabondo","year":"2003","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib5","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1111\/j.1365-2222.1993.tb03238.x","article-title":"The effect of genetic and environmental factors on the prevalence of allergic disorders at the age of two years","volume":"23","author":"Arshad","year":"1993","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jpeds.2007.04.070_bib6","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1365-2133.1996.tb03600.x","article-title":"Prevalence of atopic eczema in the community: the Lothian Atopic Dermatitis Study","volume":"135","author":"Herd","year":"1996","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib7","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1136\/adc.76.2.159","article-title":"Atopic eczema: its impact on the family and financial cost","volume":"76","author":"Su","year":"1997","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jpeds.2007.04.070_bib8","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1067\/mpd.2000.108207","article-title":"The association of atopic dermatitis in infancy with immunoglobulin E food sensitization","volume":"137","author":"Hill","year":"2000","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2007.04.070_bib9","doi-asserted-by":"crossref","first-page":"E8","DOI":"10.1542\/peds.101.3.e8","article-title":"Prevalence of IgE-mediated food allergy among children with atopic dermatitis","volume":"101","author":"Eigenmann","year":"1998","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2007.04.070_bib10","doi-asserted-by":"crossref","first-page":"S214","DOI":"10.1016\/j.jaad.2005.04.065","article-title":"Effective therapy of childhood atopic dermatitis allays food allergy concerns","volume":"53","author":"Thompson","year":"2005","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib11","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1136\/jech.54.8.581","article-title":"The epidemiology and experience of atopic eczema during childhood: a discussion paper on the implications of current knowledge for health care, public health policy and research","volume":"54","author":"Fennessy","year":"2000","journal-title":"J Epidemiol Community Health"},{"key":"10.1016\/j.jpeds.2007.04.070_bib12","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1399-3038.2004.00188.x","article-title":"The diagnostic value of skin prick testing in children with food allergy","volume":"15","author":"Hill","year":"2004","journal-title":"Pediatr Allergy Immunol"},{"issue":"Suppl 48","key":"10.1016\/j.jpeds.2007.04.070_bib13","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1365-2133.1996.tb00706.x","article-title":"Six-Area, Six-Sign Atopic Dermatitis (SASSAD) severity score: a simple system for monitoring disease activity in atopic dermatitis","volume":"135","author":"Berth-Jones","year":"1996","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib14","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1159\/000245677","article-title":"Clinical validation and guidelines for the SCORAD index: consensus report of the European Task Force on Atopic Dermatitis","volume":"195","author":"Kunz","year":"1997","journal-title":"Dermatology"},{"key":"10.1016\/j.jpeds.2007.04.070_bib15","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1080\/000155599750010256","article-title":"Scoring the severity of atopic dermatitis: the Three-Item Severity Score as a rough system for daily practice and as a pre-screening tool for studies","volume":"79","author":"Wolkerstorfer","year":"1999","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib16","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1046\/j.1365-2222.2000.00928.x","article-title":"Specificity of allergen skin testing in predicting positive open food challenges to milk, egg and peanut in children","volume":"30","author":"Sporik","year":"2000","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jpeds.2007.04.070_bib17","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1067\/mai.2001.111592","article-title":"Specific IgE levels in the diagnosis of immediate hypersensitivity to cow\u2019s milk protein in the infant","volume":"107","author":"Garc\u00eda-Ara","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib18","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1046\/j.1365-2222.2001.01175.x","article-title":"Validity of specific IgE antibodies in children with egg allergy","volume":"31","author":"Boyano","year":"2001","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jpeds.2007.04.070_bib19","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1067\/mai.2001.114708","article-title":"Utility of food-specific IgE concentrations in predicting symptomatic food allergy","volume":"107","author":"Sampson","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib20","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1365-2222.2005.02150.x","article-title":"The predictive value of specific immunoglobulin E levels in serum for the outcome of oral food challenges","volume":"35","author":"Celik-Bilgili","year":"2005","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jpeds.2007.04.070_bib21","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1542\/peds.111.S3.1631","article-title":"The natural history of food allergy","volume":"111","author":"Wood","year":"2003","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2007.04.070_bib22","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1046\/j.1365-2222.2001.01113.x","article-title":"Reducing the need for food allergen challenges in young children: a comparison of in vitro with in vivo tests","volume":"31","author":"Hill","year":"2001","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jpeds.2007.04.070_bib23","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/j.jaci.2004.03.014","article-title":"Update on food allergy","volume":"113","author":"Sampson","year":"2004","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib24","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/j.jaci.2005.12.1304","article-title":"Skin prick test to egg white provides additional diagnostic utility to serum egg white\u2013specific IgE antibody concentration in children","volume":"117","author":"Knight","year":"2006","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib25","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.4049\/jimmunol.159.4.2026","article-title":"Allergenic properties of ovomucoid in man","volume":"159","author":"Cooke","year":"1997","journal-title":"J Immunol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib26","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1067\/mai.2001.120192","article-title":"Predictors of positive food challenge outcome in non\u2013IgE-mediated reactions to food in children with atopic dermatitis","volume":"108","author":"Niggemann","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib27","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1111\/j.1365-2222.2005.02346.x","article-title":"Exposure of the fetus and infant to hen\u2019s egg ovalbumin via the placenta and breast milk in relation to maternal intake of dietary egg","volume":"35","author":"Vance","year":"2005","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jpeds.2007.04.070_bib28","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/j.jpeds.2004.03.001","article-title":"Primary prevention of atopic dermatitis in breast-fed infants: what is the evidence?","volume":"144","author":"Heine","year":"2004","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2007.04.070_bib29","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/j.1365-2222.2005.02170.x","article-title":"Effect of cooked and raw egg consumption on ovalbumin content of human milk: a randomized, double-blind, cross-over trial","volume":"35","author":"Palmer","year":"2005","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.jpeds.2007.04.070_bib30","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/S0022-3476(99)70175-7","article-title":"Cow\u2019s milk challenge through human milk evokes immune responses in infants with cow\u2019s milk allergy","volume":"135","author":"J\u00e4rvinen","year":"1999","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2007.04.070_bib31","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1542\/peds.106.2.346","article-title":"Hypoallergenic infant formulas","volume":"106","year":"2000","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2007.04.070_bib32","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1016\/j.jaci.2005.01.069","article-title":"The role of breast-feeding in the development of allergies and asthma","volume":"115","author":"Friedman","year":"2005","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib33","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/0-306-46830-1_10","article-title":"Breast-feeding and the development of cow\u2019s milk protein allergy","volume":"478","author":"Saarinen","year":"2000","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib34","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/sj.gene.6364169","article-title":"Polymorphisms within the PHF11 gene at chromosome 13q14 are associated with childhood atopic dermatitis","volume":"6","author":"Jang","year":"2005","journal-title":"Genes Immunol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib35","doi-asserted-by":"crossref","first-page":"S128","DOI":"10.1016\/j.jaci.2003.09.032","article-title":"Immune mechanisms leading to atopic dermatitis","volume":"112","author":"Novak","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib36","doi-asserted-by":"crossref","first-page":"S114","DOI":"10.1016\/S0091-6749(99)70053-9","article-title":"Food hypersensitivity and atopic dermatitis: pathophysiology, epidemiology, diagnosis, and management","volume":"104","author":"Sicherer","year":"1999","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib37","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1172\/JCI117743","article-title":"Milk-induced eczema is associated with the expansion of T cells expressing cutaneous lymphocyte antigen","volume":"95","author":"Abernathy-Carver","year":"1995","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jpeds.2007.04.070_bib38","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0091-6749(98)70410-5","article-title":"T-cell reactivity for a peanut-derived epitope in the skin of a young infant with atopic dermatitis","volume":"101","author":"van Reijsen","year":"1998","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib39","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1067\/mai.2001.114110","article-title":"Murine model of atopic dermatitis associated with food hypersensitivity","volume":"107","author":"Li","year":"2001","journal-title":"J Allergy Clin Immunol"},{"issue":"Suppl 30","key":"10.1016\/j.jpeds.2007.04.070_bib40","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1177\/0141076897090030S02","article-title":"Food sensitivity and the pathogenesis of atopic dermatitis","volume":"90","author":"Sampson","year":"1997","journal-title":"J R Soc Med"},{"key":"10.1016\/j.jpeds.2007.04.070_bib41","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/0091-6749(89)90181-4","article-title":"Effect of combined maternal and infant food-allergen avoidance on development of atopy in early infancy: a randomized study","volume":"84","author":"Zeiger","year":"1989","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.jpeds.2007.04.070_bib42","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1016\/0140-6736(92)91260-F","article-title":"Effect of allergen avoidance on development of allergic disorders in infancy","volume":"339","author":"Arshad","year":"1992","journal-title":"Lancet"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347607004465?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347607004465?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,13]],"date-time":"2023-05-13T14:28:06Z","timestamp":1683988086000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347607004465"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,10]]}},"alternative-id":["S0022347607004465"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2007.04.070","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.724905806.793503697","asserted-by":"object"}]},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2007,10]]}}}