{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:18:47Z","timestamp":1790014727013,"version":"4.0.1"},"reference-count":34,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2009,6]]},"DOI":"10.1016\/j.jpeds.2009.01.006","type":"journal-article","created":{"date-parts":[[2009,3,26]],"date-time":"2009-03-26T05:18:10Z","timestamp":1238044690000},"page":"824-828","source":"Crossref","is-referenced-by-count":33,"title":["Cerebral Blood Flow Velocities in Extremely Low Birth Weight Infants with Hypotension and Infants with Normal Blood Pressure"],"prefix":"10.1016","volume":"154","author":[{"given":"Marla H.","family":"Lightburn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Heath","family":"Gauss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. Keith","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey R.","family":"Kaiser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2009.01.006_bib1","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1542\/peds.2005-1230","article-title":"Treated hypotension is associated with neonatal morbidity and hearing loss in extremely low birth weight infants","volume":"117","author":"Fanaroff","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2009.01.006_bib2","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0378-3782(89)90120-5","article-title":"Blood pressure and cerebral haemorrhage and ischaemia in very low birthweight infants","volume":"19","author":"Watkins","year":"1989","journal-title":"Early Hum Dev"},{"key":"10.1016\/j.jpeds.2009.01.006_bib3","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1038\/sj.jp.7210563","article-title":"Variations in prevalence of hypotension, hypertension, and vasopressor use in NICUs","volume":"21","author":"Al-Aweel","year":"2001","journal-title":"J Perinatol"},{"key":"10.1016\/j.jpeds.2009.01.006_bib4","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.earlhumdev.2003.09.005","article-title":"Is hypotension a major risk factor for neurological morbidity at term age in very preterm infants?","volume":"75","author":"Martens","year":"2003","journal-title":"Early Hum Dev"},{"key":"10.1016\/j.jpeds.2009.01.006_bib5","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1542\/peds.2004-1159","article-title":"Prophylaxis of early adrenal insufficiency to prevent bronchopulmonary dysplasia: A multicenter trial","volume":"114","author":"Watterberg","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2009.01.006_bib6","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1136\/adc.67.10_Spec_No.1221","article-title":"Development of audit measures and guidelines for good practice in the management of neonatal respiratory distress syndrome","volume":"67","year":"1992","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jpeds.2009.01.006_bib7","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1136\/adc.62.10.1068","article-title":"Mean arterial blood pressure and neonatal cerebral lesions","volume":"62","author":"Miall-Allen","year":"1987","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jpeds.2009.01.006_bib8","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1542\/peds.2004-1073","article-title":"Hypotensive extremely low birth weight infants have reduced cerebral blood flow","volume":"114","author":"Munro","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2009.01.006_bib9","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1038\/sj.jp.7211579","article-title":"Diagnostic criteria and therapeutic interventions for the hypotensive very low birth weight infant","volume":"26","author":"Dempsey","year":"2006","journal-title":"J Perinatol"},{"key":"10.1016\/j.jpeds.2009.01.006_bib10","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1542\/peds.2006-1138","article-title":"Factors associated with treatment for hypotension in extremely low gestational age newborns during the first postnatal week","volume":"119","author":"Laughon","year":"2007","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2009.01.006_bib11","first-page":"1","article-title":"Early volume expansion versus inotrope for prevention of morbidity and mortality in very preterm infants","volume":"1","author":"Osborn","year":"2006","journal-title":"The Cochrane Library"},{"key":"10.1016\/j.jpeds.2009.01.006_bib12","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1542\/peds.2007-0075","article-title":"Current definitions of hypotension do not predict abnormal cranial ultrasound findings in preterm infants","volume":"120","author":"Limperopoulos","year":"2007","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2009.01.006_bib13","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/S0022-3476(98)70141-6","article-title":"Regional hemodynamic effects of dopamine in the sick preterm neonate","volume":"133","author":"Seri","year":"1998","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2009.01.006_bib14","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1067\/mpd.2001.111822","article-title":"Variations in intraventricular hemorrhage incidence rates among Canadian neonatal intensive care units","volume":"138","author":"Synnes","year":"2001","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2009.01.006_bib15","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1016\/j.clinthera.2006.09.006","article-title":"Cardiovascular support in preterm infants","volume":"28","author":"Evans","year":"2006","journal-title":"Clin Ther"},{"key":"10.1016\/j.jpeds.2009.01.006_bib16","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1542\/peds.102.2.337","article-title":"Cerebral blood flow is independent of mean arterial blood pressure in preterm infants undergoing intensive care","volume":"102","author":"Tyszczuk","year":"1998","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2009.01.006_bib17","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1203\/01.PDR.0000088071.30873.DA","article-title":"CBF reactivity in hypotensive and normotensive preterm infants","volume":"54","author":"Jayasinghe","year":"2003","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jpeds.2009.01.006_bib18","first-page":"809","article-title":"Surfactant administration acutely affects cerebral and systemic hemodynamics and gas exchange in very low birth weight infants","volume":"144","author":"Kaiser","year":"2004","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2009.01.006_bib19","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1203\/01.pdr.0000182180.80645.0c","article-title":"The effects of hypercapnia on cerebral autoregulation in ventilated very low birth weight infants","volume":"58","author":"Kaiser","year":"2005","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jpeds.2009.01.006_bib20","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/sj.jp.7211848","article-title":"Tracheal suctioning is associated with prolonged disturbances of cerebral hemodynamics in very low birth weight infants","volume":"28","author":"Kaiser","year":"2008","journal-title":"J Perinatol"},{"key":"10.1016\/j.jpeds.2009.01.006_bib21","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1542\/peds.2004-1396","article-title":"Cardiovascular support for low birth weight infants and cerebral hemodynamics: A randomized, blinded, clinical trial","volume":"115","author":"Pellicer","year":"2005","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2009.01.006_bib22","series-title":"Pediatric Applications of Transcranial Doppler Sonography","author":"Bode","year":"1988"},{"key":"10.1016\/j.jpeds.2009.01.006_bib23","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0022-3476(78)80282-0","article-title":"Incidence and evolution of subependymal and intraventricular hemorrhage: A study of infants with birth weights less than 1500 gm","volume":"92","author":"Papile","year":"1978","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2009.01.006_bib24","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/S0022-3476(96)70114-2","article-title":"Relationship between blood pressure and cardiac output in preterm infants requiring mechanical ventilation","volume":"129","author":"Kluckow","year":"1996","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2009.01.006_bib25","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1007\/s004310051213","article-title":"Left ventricle output and mean arterial blood pressure in preterm infants during the 1st day of life","volume":"158","author":"Pladys","year":"1999","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.jpeds.2009.01.006_bib26","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0022-3476(84)81108-7","article-title":"Cerebral blood flow in the newborn infant: Comparison of Doppler ultrasound and 133xenon clearance","volume":"104","author":"Greisen","year":"1984","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2009.01.006_bib27","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1111\/j.1651-2227.1995.tb13579.x","article-title":"Postnatal development of the cerebral blood flow velocity response to changes in CO2 and mean arterial blood pressure in the piglet","volume":"84","author":"Haaland","year":"1995","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.jpeds.2009.01.006_bib28","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1203\/00006450-198311000-00014","article-title":"Regional cerebral blood flow, cerebral blood velocity, and pulsatility index in newborn dogs","volume":"17","author":"Batton","year":"1983","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jpeds.2009.01.006_bib29","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1203\/01.PDR.0000147576.84092.F9","article-title":"Identification of pressure passive cerebral perfusion and its mediators after infant cardiac surgery","volume":"57","author":"Bassan","year":"2005","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jpeds.2009.01.006_bib30","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1203\/00006450-199810000-00020","article-title":"Near infrared spectroscopy detects cerebral ischemia during hypotension in piglets","volume":"44","author":"Tsuji","year":"1998","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jpeds.2009.01.006_bib31","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0887-8994(00)00239-3","article-title":"Postnatal adaptation of brain circulation in preterm infants","volume":"24","author":"Pellicer","year":"2001","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.jpeds.2009.01.006_bib32","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/S0022-3476(97)70060-X","article-title":"Comparative evaluation of the effects of indomethacin and ibuprofen on cerebral perfusion and oxygenation in preterm infants with patent ductus arteriosus","volume":"131","author":"Mosca","year":"1997","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2009.01.006_bib33","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1056\/NEJM198307283090402","article-title":"Fluctuating cerebral blood-flow velocity in respiratory-distress syndrome","volume":"309","author":"Perlman","year":"1983","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jpeds.2009.01.006_bib34","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jpeds.2005.12.056","article-title":"Cardiovascular support in the preterm: Treatments in search of indications","volume":"148","author":"Barrington","year":"2006","journal-title":"J Pediatr"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347609000043?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347609000043?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,20]],"date-time":"2018-12-20T16:54:55Z","timestamp":1545324895000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347609000043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,6]]}},"alternative-id":["S0022347609000043"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2009.01.006","relation":{},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2009,6]]}}}