{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T01:22:02Z","timestamp":1791076922856,"version":"4.1.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1016\/j.jpeds.2013.06.024","type":"journal-article","created":{"date-parts":[[2013,7,26]],"date-time":"2013-07-26T21:00:34Z","timestamp":1374872434000},"page":"1448-1453","source":"Crossref","is-referenced-by-count":105,"title":["Delayed Diagnosis in Children with Intracranial Germ Cell Tumors"],"prefix":"10.1016","volume":"163","author":[{"given":"Roshan V.","family":"Sethi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rose","family":"Marino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"Niemierko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy J.","family":"Tarbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torunn I.","family":"Yock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon M.","family":"MacDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2013.06.024_bib1","doi-asserted-by":"crossref","first-page":"155","DOI":"10.3171\/jns.1985.63.2.0155","article-title":"Intracranial germ-cell tumors: natural history and pathogenesis","volume":"63","author":"Jennings","year":"1985","journal-title":"J Neurosurg"},{"key":"10.1016\/j.jpeds.2013.06.024_bib2","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1215\/15228517-2007-054","article-title":"Malignant pineal germ-cell tumors: an analysis of cases from three tumor registries","volume":"10","author":"Villano","year":"2008","journal-title":"Neuro Oncol"},{"key":"10.1016\/j.jpeds.2013.06.024_bib3","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/0360-3016(90)90396-2","article-title":"Pineal and CNS germ cell tumors: Royal Marsden Hospital experience 1962-1987","volume":"18","author":"Dearnaley","year":"1990","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.jpeds.2013.06.024_bib4","doi-asserted-by":"crossref","first-page":"446","DOI":"10.3171\/jns.1997.86.3.0446","article-title":"Primary intracranial germ cell tumors: a clinical analysis of 153 histologically verified cases","volume":"86","author":"Matsutani","year":"1997","journal-title":"J Neurosurg"},{"key":"10.1016\/j.jpeds.2013.06.024_bib5","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1159\/000413688","article-title":"Primary intracranial germ cell tumors: pathology and treatment","volume":"30","author":"Matsutani","year":"1987","journal-title":"Prog Exp Tumor Res"},{"key":"10.1016\/j.jpeds.2013.06.024_bib6","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.3171\/foc.1998.5.1.10","article-title":"Combined chemotherapy and radiation therapy for central nervous system germ cell tumors: preliminary results of a Phase II study of the Japanese Pediatric Brain Tumor Study Group","volume":"5","author":"Matsutani","year":"1998","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.jpeds.2013.06.024_bib7","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1200\/JCO.2004.11.053","article-title":"Thiotepa-based high-dose chemotherapy with autologous stem-cell rescue in patients with recurrent or progressive CNS germ cell tumors","volume":"22","author":"Modak","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jpeds.2013.06.024_bib8","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1023\/A:1005732105727","article-title":"Improved prognosis of intracranial non-germinoma germ cell tumors with multimodality therapy","volume":"32","author":"Robertson","year":"1997","journal-title":"J Neurooncol"},{"key":"10.1016\/j.jpeds.2013.06.024_bib9","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1023\/B:NEON.0000027670.96412.36","article-title":"Intracranial germ cell tumors: a single institution experience and review of the literature","volume":"68","author":"Smith","year":"2004","journal-title":"J Neurooncol"},{"issue":"Suppl 5","key":"10.1016\/j.jpeds.2013.06.024_bib10","doi-asserted-by":"crossref","first-page":"v1","DOI":"10.1093\/neuonc\/nos218","article-title":"CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2005-2009","volume":"14","author":"Dolecek","year":"2012","journal-title":"Neuro Oncol"},{"key":"10.1016\/j.jpeds.2013.06.024_bib11","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.ijrobp.2009.10.069","article-title":"Proton radiotherapy for pediatric central nervous system germ cell tumors: early clinical outcomes","volume":"79","author":"MacDonald","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.jpeds.2013.06.024_bib12","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1212\/01.wnl.0000261908.36803.ac","article-title":"CNS germ cell tumor (CNSGCT) of childhood: presentation and delayed diagnosis","volume":"68","author":"Crawford","year":"2007","journal-title":"Neurology"},{"key":"10.1016\/j.jpeds.2013.06.024_bib13","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s00431-008-0755-5","article-title":"Does diagnostic delay result in decreased survival in paediatric brain tumours?","volume":"168","author":"Kukal","year":"2009","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.jpeds.2013.06.024_bib14","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0360-3016(97)00330-1","article-title":"Intracranial germinoma: the case for lower-dose radiation therapy","volume":"39","author":"Hardenbergh","year":"1997","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.jpeds.2013.06.024_bib15","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s00431-002-1088-4","article-title":"Delay in the diagnosis of paediatric brain tumours","volume":"161","author":"Dobrovoljac","year":"2002","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.jpeds.2013.06.024_bib16","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1227\/00006123-200208000-00012","article-title":"Latency between symptom onset and diagnosis of pediatric brain tumors: an Eastern Canadian geographic study","volume":"51","author":"Mehta","year":"2002","journal-title":"Neurosurgery"},{"key":"10.1016\/j.jpeds.2013.06.024_bib17","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1177\/0883073807308692","article-title":"Brain tumors in children: initial symptoms and their influence on the time span between symptom onset and diagnosis","volume":"23","author":"Reulecke","year":"2008","journal-title":"J Child Neurol"},{"key":"10.1016\/j.jpeds.2013.06.024_bib18","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1136\/adc.68.6.771","article-title":"Determinants of symptom interval in childhood cancer","volume":"68","author":"Saha","year":"1993","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jpeds.2013.06.024_bib19","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s00381-011-1564-0","article-title":"Diagnostic delay of pediatric brain tumors in Israel: a retrospective risk factor analysis","volume":"28","author":"Shay","year":"2012","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.jpeds.2013.06.024_bib20","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1136\/adc.2005.090266","article-title":"The presenting features of brain tumours: a review of 200 cases","volume":"91","author":"Wilne","year":"2006","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jpeds.2013.06.024_bib21","doi-asserted-by":"crossref","first-page":"e445","DOI":"10.1016\/S1470-2045(12)70361-3","article-title":"Delays in diagnosis of paediatric cancers: a systematic review and comparison with expert testimony in lawsuits","volume":"13","author":"Brasme","year":"2012","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.jpeds.2013.06.024_bib22","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1056\/NEJM200010053431403","article-title":"Central diabetes insipidus in children and young adults","volume":"343","author":"Maghnie","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jpeds.2013.06.024_bib23","doi-asserted-by":"crossref","first-page":"4776","DOI":"10.1200\/JCO.2011.37.9453","article-title":"Growth hormone secretion after conformal radiation therapy in pediatric patients with localized brain tumors","volume":"29","author":"Merchant","year":"2011","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jpeds.2013.06.024_bib24","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1200\/JCO.1991.9.8.1348","article-title":"A prospective comparison of neuropsychologic performance of children surviving leukemia who received 18-Gy, 24-Gy, or no cranial irradiation","volume":"9","author":"Mulhern","year":"1991","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jpeds.2013.06.024_bib25","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1093\/jnci\/93.8.618","article-title":"Second malignant neoplasms in five-year survivors of childhood cancer: childhood cancer survivor study","volume":"93","author":"Neglia","year":"2001","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.jpeds.2013.06.024_bib26","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.ijrobp.2003.07.008","article-title":"Early neuro-otologic effects of three-dimensional irradiation in children with primary brain tumors","volume":"58","author":"Merchant","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.jpeds.2013.06.024_bib27","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1016\/j.ijrobp.2007.08.085","article-title":"Vertebral body growth after craniospinal irradiation","volume":"70","author":"Hartley","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347613007373?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347613007373?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,19]],"date-time":"2019-07-19T14:40:07Z","timestamp":1563547207000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347613007373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["S0022347613007373"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2013.06.024","relation":{},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2013,11]]}}}