{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:04:13Z","timestamp":1762866253500},"reference-count":13,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1016\/j.jpeds.2013.08.029","type":"journal-article","created":{"date-parts":[[2013,9,29]],"date-time":"2013-09-29T09:47:15Z","timestamp":1380448035000},"page":"1705-1710.e1","source":"Crossref","is-referenced-by-count":27,"title":["Infectious Precipitants of Acute Hyperammonemia Are Associated with Indicators of Increased Morbidity in Patients with Urea Cycle Disorders"],"prefix":"10.1016","volume":"163","author":[{"given":"Peter J.","family":"McGuire","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye-Seung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marshall L.","family":"Summar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2013.08.029_bib1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.ymgme.2009.02.009","article-title":"Quantitative RT-PCR comparison of the urea and nitric oxide cycle gene transcripts in adult human tissues","volume":"97","author":"Neill","year":"2009","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.jpeds.2013.08.029_bib2","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.1067\/mpd.2001.111831","article-title":"Proceedings of a consensus conference for the management of patients with urea cycle disorders","volume":"138","author":"Summar","year":"2001","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2013.08.029_bib3","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1111\/j.1651-2227.2008.00952.x","article-title":"Diagnosis, symptoms, frequency and mortality of 260 patients with urea cycle disorders from a 21-year, multicentre study of acute hyperammonaemic episodes","volume":"97","author":"Summar","year":"2008","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.jpeds.2013.08.029_bib4","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.ymgme.2008.05.004","article-title":"Cross-sectional multicenter study of patients with urea cycle disorders in the United States","volume":"94","author":"Tuchman","year":"2008","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.jpeds.2013.08.029_bib5","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1093\/ajcn\/9.2.154","article-title":"Infection and nutritional status, I: the effect of chicken pox on nitrogen metabolism in children","volume":"9","author":"Wilson","year":"1961","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jpeds.2013.08.029_bib6","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1016\/j.ccc.2005.08.003","article-title":"Nutritional management of urea cycle disorders","volume":"21","author":"Singh","year":"2005","journal-title":"Crit Care Clin"},{"key":"10.1016\/j.jpeds.2013.08.029_bib7","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1146\/annurev.me.26.020175.000301","article-title":"Metabolic response to infection","volume":"26","author":"Beisel","year":"1975","journal-title":"Annu Rev Med"},{"key":"10.1016\/j.jpeds.2013.08.029_bib8","first-page":"62","article-title":"A new method of determining and analyzing seasonality of acute infectious diseases","volume":"47","author":"Bratovanov","year":"1970","journal-title":"Z Mikrobiol Epidemiol Immunobiol"},{"key":"10.1016\/j.jpeds.2013.08.029_bib9","series-title":"The mechanism of heat loss and temperature regualtion","author":"Dubois","year":"1937"},{"key":"10.1016\/j.jpeds.2013.08.029_bib10","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.jhep.2003.10.016","article-title":"Systemic inflammatory response exacerbates the neuropsychological effects of induced hyperammonemia in cirrhosis","volume":"40","author":"Shawcross","year":"2004","journal-title":"J Hepatol"},{"key":"10.1016\/j.jpeds.2013.08.029_bib11","first-page":"449","article-title":"Elevated plasma interleukin-6 and increased severity and mortality in alcoholic hepatitis","volume":"84","author":"Sheron","year":"1991","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.jpeds.2013.08.029_bib12","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.ymgme.2005.12.013","article-title":"Hyperammonemia increases sensitivity to LPS","volume":"88","author":"Marini","year":"2006","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.jpeds.2013.08.029_bib13","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1067\/mpd.2001.111830","article-title":"Consensus statement from a conference for the management of patients with urea cycle disorders","volume":"138","author":"Urea Cycle Disorders Conference Group","year":"2001","journal-title":"J\u00a0Pediatr"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347613010019?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347613010019?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T17:21:24Z","timestamp":1564161684000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347613010019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["S0022347613010019"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2013.08.029","relation":{},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2013,12]]}}}