{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T15:08:05Z","timestamp":1792681685029,"version":"4.5.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpeds.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.jpeds.2014.04.060","type":"journal-article","created":{"date-parts":[[2014,6,16]],"date-time":"2014-06-16T17:01:13Z","timestamp":1402938073000},"page":"556-563.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":105,"title":["Effects of Pump versus Twice-Daily Injection Delivery of Synthetic Parathyroid Hormone 1-34 in Children with Severe Congenital\u00a0Hypoparathyroidism"],"prefix":"10.1016","volume":"165","author":[{"given":"Karen K.","family":"Winer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kara A.","family":"Fulton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul S.","family":"Albert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Gordon B.","family":"Cutler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2014.04.060_bib1","doi-asserted-by":"crossref","first-page":"3307","DOI":"10.1210\/jc.2008-1216","article-title":"Hypoparathyroidism: is it time for replacement therapy?","volume":"93","author":"Horwitz","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpeds.2014.04.060_bib2","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1007\/s00198-012-2230-4","article-title":"PTH replacement therapy of hypoparathyroidism","volume":"24","author":"Rejnmark","year":"2013","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.jpeds.2014.04.060_bib3","first-page":"273","article-title":"Nephrocalcinosis in children and adolescents: sonographic evaluation during long-term treatment with 1,25-dihydrocholecalciferol","volume":"9","author":"Weber","year":"1988","journal-title":"Child Nephrol Urol"},{"key":"10.1016\/j.jpeds.2014.04.060_bib4","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1001\/archpedi.1986.02140160057032","article-title":"Hypercalciuria associated with long term administration of calcitriol (1,25-dihydroxyvitamin D)","volume":"140","author":"Santos","year":"1986","journal-title":"Am J Dis Child"},{"key":"10.1016\/j.jpeds.2014.04.060_bib5","first-page":"3480","article-title":"A randomized, crossover trial of once-daily vs twice-daily human parathyroid hormone 1-34 in the treatment of hypoparathyroidism","volume":"83","author":"Winer","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpeds.2014.04.060_bib6","doi-asserted-by":"crossref","first-page":"3308","DOI":"10.1210\/jc.2011-1359","article-title":"Long-term results of continuous subcutaneous recombinant PTH 1-34 infusion in children with refractory hypoparathyroidism","volume":"96","author":"Linglart","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpeds.2014.04.060_bib7","first-page":"141","article-title":"First experiences in the substitution treatment of hypoparathyroidism with synthetic human parathyroid hormone","volume":"138","author":"Strogmann","year":"1990","journal-title":"Monatsschr Kinderheilkd"},{"key":"10.1016\/j.jpeds.2014.04.060_bib8","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1001\/jama.1996.03540080053029","article-title":"Synthetic human parathyroid hormone 1-34 vs calcitriol and calcium in the treatment of hypoparathyroidism: results of a randomized crossover trial","volume":"276","author":"Winer","year":"1996","journal-title":"JAMA"},{"key":"10.1016\/j.jpeds.2014.04.060_bib9","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.1210\/jc.2007-2552","article-title":"Effects of once-daily versus twice-daily parathyroid hormone 1-34 in children with hypoparathyroidism","volume":"93","author":"Winer","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpeds.2014.04.060_bib10","first-page":"391","article-title":"Synthetic human parathyroid hormone 1-34 replacement therapy: a randomized crossover trial comparing pump versus injections in the treatment of chronic hypoparathyroidism","volume":"97","author":"Winer","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpeds.2014.04.060_bib11","doi-asserted-by":"crossref","first-page":"4214","DOI":"10.1210\/jc.2002-021736","article-title":"Long-term treatment of hypoparathyroidism: a randomized controlled study comparing parathyroid hormone 1-34 and calcitriol and calcium","volume":"88","author":"Winer","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpeds.2014.04.060_bib12","doi-asserted-by":"crossref","first-page":"2680","DOI":"10.1210\/jc.2009-2464","article-title":"Long-term treatment of 12 children with chronic hypoparathyroidism: a randomized trial comparing synthetic human parathyroid hormone 1-34 versus calcitriol and calcium","volume":"95","author":"Winer","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpeds.2014.04.060_bib13","doi-asserted-by":"crossref","first-page":"2358","DOI":"10.1002\/jbmr.470","article-title":"The effect of adding PTH 1-84 to conventional treatment of hypoparathyrodism","volume":"26","author":"Sikjaer","year":"2011","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.jpeds.2014.04.060_bib14","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1210\/jc.2012-2984","article-title":"Therapy of hypoparathyroidism with intact parathyroid hormone 1-84: a prospective four year investigation of efficacy and safety","volume":"1","author":"Cusano","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpeds.2014.04.060_bib15","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1007\/s00198-009-1149-x","article-title":"Therapy of hypoparathyroidism with intact parathyroid hormone","volume":"21","author":"Rubin","year":"2010","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.jpeds.2014.04.060_bib16","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1530\/EJE-08-0269","article-title":"Successful treatment of vitamin D unresponsive hypoparathyroidism with multipulse subcutaneous infusion of teriperatide","volume":"159","author":"Puig-Domingo","year":"2008","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.jpeds.2014.04.060_bib17","first-page":"399","article-title":"Pulsatile secretion of parathyroid hormone in normal young subjects: assessment by deconvolution analysis","volume":"77","author":"Samuels","year":"1993","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpeds.2014.04.060_bib18","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1210\/jcem-69-4-843","article-title":"Pulse amplitude and frequency modulation of parathyroid hormone in plasma","volume":"69","author":"Harms","year":"1989","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpeds.2014.04.060_bib19","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1136\/jcp.21.3.353","article-title":"Tubular reabsorption of calcium in normal and hypercalciuric subjects","volume":"221","author":"Peacock","year":"1968","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.jpeds.2014.04.060_bib20","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1740-3391-8-10","article-title":"Statistical methods for detecting and comparing periodic data and their application to the nycthemeral rhythm of bodily harm: a population based study","volume":"8","author":"Stroebel","year":"2010","journal-title":"J Circadian Rhythms"},{"key":"10.1016\/j.jpeds.2014.04.060_bib21","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1111\/j.0006-341X.2005.464_1.x","article-title":"On analyzing circadian rhythms data using nonlinear mixed modes with harmonic terms","volume":"61","author":"Albert","year":"2005","journal-title":"Biometrics"},{"key":"10.1016\/j.jpeds.2014.04.060_bib22","series-title":"Mixed-effects models in S and S-Plus","author":"Pinheiro","year":"2000"},{"key":"10.1016\/j.jpeds.2014.04.060_bib23","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1007\/BF00865491","article-title":"Assessment and interpretation of the tubular threshold for phosphate in infants and children","volume":"8","author":"Alon","year":"1994","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.jpeds.2014.04.060_bib24","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/BF00862587","article-title":"Assessment of maximal tubular phosphate reabsorption: comparison of direct measurement with the nomogram of Bijvoet","volume":"2","author":"Brodehl","year":"1988","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.jpeds.2014.04.060_bib25","doi-asserted-by":"crossref","first-page":"4507","DOI":"10.1210\/jc.2012-1808","article-title":"Long-term follow-up of patients with hypoparathyroidism","volume":"97","author":"Michell","year":"2012","journal-title":"J Clin Endocrinol Metab"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347614004181?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347614004181?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T08:56:52Z","timestamp":1758358612000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347614004181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S0022347614004181"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2014.04.060","relation":{},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of Pump versus Twice-Daily Injection Delivery of Synthetic Parathyroid Hormone 1-34 in Children with Severe Congenital\u00a0Hypoparathyroidism","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pediatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpeds.2014.04.060","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Mosby, Inc.","name":"copyright","label":"Copyright"}]}}