{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T20:23:35Z","timestamp":1786479815473,"version":"build-2736575974"},"reference-count":47,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","jpeds.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2015,11]]},"DOI":"10.1016\/j.jpeds.2015.07.054","type":"journal-article","created":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T05:22:55Z","timestamp":1441084975000},"page":"1067-1073","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["The Effects of Sex and Pubertal Maturation on Cardiovagal Baroreflex Sensitivity"],"prefix":"10.1016","volume":"167","author":[{"given":"Daniele","family":"Chirico","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panagiota","family":"Klentrou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Kevin","family":"Shoemaker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah D.","family":"O'Leary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2015.07.054_bib1","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1212\/01.wnl.0000335246.93495.92","article-title":"The arterial baroreflex: functional organization and involvement in neurologic disease","volume":"71","author":"Benarroch","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/j.jpeds.2015.07.054_bib2","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1152\/japplphysiol.00158.2006","article-title":"Baroreflex sensitivity, blood pressure buffering, and resonance: what are the links? Computer simulation of healthy subjects and heart failure patients","volume":"102","author":"Van de Vooren","year":"2007","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.jpeds.2015.07.054_bib3","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1161\/01.RES.34.4.515","article-title":"Human splanchnic and forearm vasoconstrictor responses to reductions of right atrial and aortic pressures","volume":"34","author":"Johnson","year":"1974","journal-title":"Circ Res"},{"key":"10.1016\/j.jpeds.2015.07.054_bib4","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1542-474X.2008.00219.x","article-title":"Baroreflex sensitivity: measurement and clinical implications","volume":"13","author":"La Rovere","year":"2008","journal-title":"Ann Noninvasive Electrocardiol"},{"key":"10.1016\/j.jpeds.2015.07.054_bib5","doi-asserted-by":"crossref","first-page":"R1107","DOI":"10.1152\/ajpregu.00559.2012","article-title":"Spontaneous fluctuation indices of the cardiovagal baroreflex accurately measure the baroreflex sensitivity at the operating point during upright tilt","volume":"304","author":"Schwartz","year":"2013","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.jpeds.2015.07.054_bib6","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/S0140-6736(97)11144-8","article-title":"Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction. ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) Investigators","volume":"351","author":"La Rovere","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.jpeds.2015.07.054_bib7","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1139\/h11-163","article-title":"The association between baroreflex sensitivity and blood pressure in children","volume":"37","author":"Fitzgibbon","year":"2012","journal-title":"Appl Physiol Nutr Metab"},{"key":"10.1016\/j.jpeds.2015.07.054_bib8","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s10286-011-0116-8","article-title":"Impaired autonomic function in normotensive obese children","volume":"21","author":"Latchman","year":"2011","journal-title":"Clin Auton Res"},{"key":"10.1016\/j.jpeds.2015.07.054_bib9","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1161\/01.CIR.0000145157.07881.A3","article-title":"Maturation of cardiovagal\u00a0autonomic function from childhood to young adult age","volume":"110","author":"Lenard","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.jpeds.2015.07.054_bib10","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1139\/y06-060","article-title":"Can we detect the development of baroreflex sensitivity in humans between 11 and 20 years of age?","volume":"84","author":"Zavodna","year":"2006","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1016\/j.jpeds.2015.07.054_bib11","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1097\/01.hjh.0000200517.27356.47","article-title":"Spontaneous baroreflex sensitivity in (pre)adolescents","volume":"24","author":"Dietrich","year":"2006","journal-title":"J Hypertens"},{"key":"10.1016\/j.jpeds.2015.07.054_bib12","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1097\/00005344-200111000-00012","article-title":"Testosterone facilitates the baroreceptor control of reflex bradycardia: role of cardiac sympathetic and parasympathetic components","volume":"38","author":"El-Mas","year":"2001","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1016\/j.jpeds.2015.07.054_bib13","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1139\/y98-031","article-title":"Estrogen enhances baroreflex control of heart rate in conscious ovariectomized rats","volume":"76","author":"el-Mas","year":"1998","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1016\/j.jpeds.2015.07.054_bib14","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1530\/EJE-12-0669","article-title":"Deciphering puberty: novel partners, novel mechanisms","volume":"167","author":"Tena-Sempere","year":"2012","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.jpeds.2015.07.054_bib15","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.mce.2009.12.018","article-title":"Metabolic control of puberty onset: new players, new mechanisms","volume":"324","author":"Roa","year":"2010","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.jpeds.2015.07.054_bib16","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.ridd.2010.09.013","article-title":"Left ventricular structure and function in children with and without developmental coordination disorder","volume":"32","author":"Chirico","year":"2011","journal-title":"Res Dev Disabil"},{"key":"10.1016\/j.jpeds.2015.07.054_bib17","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1093\/ajcn\/75.3.453","article-title":"Body-composition assessment via air-displacement plethysmography in adults and children: a review","volume":"75","author":"Fields","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jpeds.2015.07.054_bib18","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1136\/adc.44.235.291","article-title":"Variations in pattern of pubertal changes in girls","volume":"44","author":"Marshall","year":"1969","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jpeds.2015.07.054_bib19","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1136\/adc.45.239.13","article-title":"Variations in the pattern of pubertal changes in boys","volume":"45","author":"Marshall","year":"1970","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jpeds.2015.07.054_bib20","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1046\/j.1365-3016.2001.00317.x","article-title":"Performance of a new pubertal self-assessment questionnaire: a preliminary study","volume":"15","author":"Taylor","year":"2001","journal-title":"Paediatr Perinat Epidemiol"},{"key":"10.1016\/j.jpeds.2015.07.054_bib21","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1109\/TAU.1967.1161901","article-title":"The use of fast Fourier transform for the estimation of power spectra: a method based on time averaging over short, modified periodogram","volume":"15","author":"Welch","year":"1967","journal-title":"IEEE Trans Audio Electroacoustics"},{"key":"10.1016\/j.jpeds.2015.07.054_bib22","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1161\/01.HYP.10.5.538","article-title":"Assessment of baroreceptor reflex sensitivity by means of spectral analysis","volume":"10","author":"Robbe","year":"1987","journal-title":"Hypertension"},{"key":"10.1016\/j.jpeds.2015.07.054_bib23","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1097\/00004872-200206000-00029","article-title":"Carotid diameter variations as a non-invasive tool to examine cardiac baroreceptor sensitivity","volume":"20","author":"Kornet","year":"2002","journal-title":"J Hypertens"},{"key":"10.1016\/j.jpeds.2015.07.054_bib24","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1210\/jc.2004-0926","article-title":"The change in blood pressure during pubertal growth","volume":"90","author":"Shankar","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpeds.2015.07.054_bib25","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1111\/j.1651-2227.1986.tb10262.x","article-title":"Blood pressure in puberty","volume":"75","author":"Vartiainen","year":"1986","journal-title":"Acta Paediatr Scand"},{"key":"10.1016\/j.jpeds.2015.07.054_bib26","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1067\/mpd.2000.108098","article-title":"Blood pressure and cardiovascular autonomic function in healthy children and adolescents","volume":"137","author":"Tanaka","year":"2000","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2015.07.054_bib27","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1080\/02701367.2014.897592","article-title":"Top 10 research questions related to growth and maturation of relevance to physical activity, performance, and fitness","volume":"85","author":"Malina","year":"2014","journal-title":"Res Q Exerc Sport"},{"key":"10.1016\/j.jpeds.2015.07.054_bib28","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1016\/j.jpeds.2013.07.002","article-title":"Impact of pubertal development on endothelial function and arterial elasticity","volume":"163","author":"Marlatt","year":"2013","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2015.07.054_bib29","first-page":"35","article-title":"Baroreflex sensitivity and body growth parameters in children and adolescents","volume":"6","author":"Novakova","year":"2001","journal-title":"Exp Clin Cardiol"},{"key":"10.1016\/j.jpeds.2015.07.054_bib30","doi-asserted-by":"crossref","first-page":"605","DOI":"10.33549\/physiolres.931700","article-title":"Baroreflex sensitivity and essential hypertension in adolescents","volume":"58","author":"Honzikova","year":"2009","journal-title":"Physiol Res"},{"key":"10.1016\/j.jpeds.2015.07.054_bib31","first-page":"58","article-title":"Circulating testosterone and estradiol, autonomic balance and baroreflex sensitivity in middle-aged and elderly men with heart failure","volume":"16","author":"Rydlewska","year":"2013","journal-title":"Aging\u00a0Male"},{"key":"10.1016\/j.jpeds.2015.07.054_bib32","first-page":"R1030","article-title":"Estrogen enhancement of baroreflex sensitivity is centrally mediated","volume":"276","author":"Mohamed","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jpeds.2015.07.054_bib33","doi-asserted-by":"crossref","first-page":"R1091","DOI":"10.1152\/ajpregu.00162.2003","article-title":"Influence of menstrual cycle\u00a0on baroreflex control of heart rate: comparison with male volunteers","volume":"285","author":"Tanaka","year":"2003","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.jpeds.2015.07.054_bib34","doi-asserted-by":"crossref","first-page":"2088","DOI":"10.1152\/jappl.2001.91.5.2088","article-title":"Gender difference in cardiovagal\u00a0baroreflex gain in humans","volume":"91","author":"Beske","year":"2001","journal-title":"J Appl Physiol (1985)"},{"key":"10.1016\/j.jpeds.2015.07.054_bib35","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1161\/01.HYP.37.3.911","article-title":"Determinants of spontaneous baroreflex sensitivity in a healthy working population","volume":"37","author":"Kardos","year":"2001","journal-title":"Hypertension"},{"key":"10.1016\/j.jpeds.2015.07.054_bib36","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1152\/jappl.1998.84.2.576","article-title":"Age and gender dependency of baroreflex sensitivity in healthy subjects","volume":"84","author":"Laitinen","year":"1998","journal-title":"J Appl Physiol (1985)"},{"key":"10.1016\/j.jpeds.2015.07.054_bib37","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1161\/01.HYP.0000165695.98915.9a","article-title":"Baroreflex regulation of heart rate and sympathetic vasomotor tone in women and men","volume":"45","author":"Tank","year":"2005","journal-title":"Hypertension"},{"key":"10.1016\/j.jpeds.2015.07.054_bib38","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1002\/mus.24191","article-title":"Determination of vagal baroreflex sensitivity in normal subjects","volume":"50","author":"Wada","year":"2014","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.jpeds.2015.07.054_bib39","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1042\/cs0990371","article-title":"Baroreflex sensitivity in the elderly: influence of age, breathing and spectral methods","volume":"99","author":"Gerritsen","year":"2000","journal-title":"Clin Sci (Lond)"},{"key":"10.1016\/j.jpeds.2015.07.054_bib40","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1161\/hc3901.096670","article-title":"Central arterial compliance is associated with age- and habitual exercise-related differences\u00a0in cardiovagal baroreflex sensitivity","volume":"104","author":"Monahan","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.jpeds.2015.07.054_bib41","first-page":"H1139","article-title":"Relation between baroreflex sensitivity and carotid artery elasticity in healthy humans","volume":"271","author":"Bonyhay","year":"1996","journal-title":"Am J Physiol"},{"key":"10.1016\/j.jpeds.2015.07.054_bib42","doi-asserted-by":"crossref","first-page":"2424","DOI":"10.1161\/01.CIR.103.20.2424","article-title":"Does reduced vascular stiffening fully explain preserved cardiovagal baroreflex function in older, physically active men?","volume":"103","author":"Hunt","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.jpeds.2015.07.054_bib43","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/j.1748-1716.2005.01505.x","article-title":"Fluctuations in carotid arterial distensibility during the menstrual cycle do not influence cardiovagal baroreflex sensitivity","volume":"186","author":"Hayashi","year":"2006","journal-title":"Acta Physiol (Oxf)"},{"key":"10.1016\/j.jpeds.2015.07.054_bib44","doi-asserted-by":"crossref","first-page":"5375","DOI":"10.1210\/jc.2003-030722","article-title":"Gender differences in large artery stiffness pre- and post puberty","volume":"88","author":"Ahimastos","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpeds.2015.07.054_bib45","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.biopsycho.2010.05.005","article-title":"Reproducibility of heart rate variability and baroreflex sensitivity measurements in children","volume":"85","author":"Dietrich","year":"2010","journal-title":"Biol Psychol"},{"key":"10.1016\/j.jpeds.2015.07.054_bib46","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1123\/pes.22.3.442","article-title":"Confounding effect of biologic maturation on sex differences in physical activity and sedentary behavior in adolescents","volume":"22","author":"Machado Rodrigues","year":"2010","journal-title":"Pediatr Exerc Sci"},{"key":"10.1016\/j.jpeds.2015.07.054_bib47","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1001\/jama.300.3.295","article-title":"Moderate-to-vigorous physical activity from ages 9 to 15 years","volume":"300","author":"Nader","year":"2008","journal-title":"JAMA"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002234761500832X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002234761500832X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,21]],"date-time":"2022-05-21T04:54:37Z","timestamp":1653108877000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002234761500832X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11]]},"references-count":47,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["S002234761500832X"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2015.07.054","relation":{},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2015,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Effects of Sex and Pubertal Maturation on Cardiovagal Baroreflex Sensitivity","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pediatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpeds.2015.07.054","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}