{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T14:59:00Z","timestamp":1770821940167,"version":"3.50.1"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","jpeds.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1016\/j.jpeds.2018.02.039","type":"journal-article","created":{"date-parts":[[2018,4,5]],"date-time":"2018-04-05T17:43:52Z","timestamp":1522950232000},"page":"53-59","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Catheter-Related Venous Thrombosis in Hospitalized Pediatric Patients with Inflammatory Bowel Disease: Incidence, Characteristics, and Role of Anticoagulant Thromboprophylaxis with Enoxaparin"],"prefix":"10.1016","volume":"198","author":[{"given":"Carrie E.","family":"Diamond","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carole","family":"Hennessey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2595-6338","authenticated-orcid":false,"given":"Jennifer","family":"Meldau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine J.","family":"Guelcher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael F.","family":"Guerrera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurie S.","family":"Conklin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karun V.","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaser A.","family":"Diab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2018.02.039_bib0010","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/MPG.0b013e3181b99baa","article-title":"Rising incidence of inflammatory bowel disease among children: a 12-year study","volume":"50","author":"Malaty","year":"2010","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0015","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1097\/MIB.0000000000000195","article-title":"Increasing hospitalizations in inflammatory bowel disease among children in the United States, 1988-2011","volume":"20","author":"Sandberg","year":"2014","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0020","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1136\/gut.2010.228585","article-title":"Thromboembolic risk among Danish children and adults with inflammatory bowel diseases: a population-based nationwide study","volume":"60","author":"Kappelman","year":"2011","journal-title":"Gut"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0025","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1097\/MPG.0b013e3182801e43","article-title":"Venous thrombotic events in hospitalized children and adolescents with inflammatory bowel disease","volume":"56","author":"Nylund","year":"2013","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0030","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/S0140-6736(09)61963-2","article-title":"Venous thromboembolism during active disease and remission in inflammatory bowel disease: a cohort study","volume":"375","author":"Grainge","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0035","doi-asserted-by":"crossref","first-page":"2272","DOI":"10.1111\/j.1572-0241.2008.02052.x","article-title":"Rising prevalence of venous thromboembolism and its impact on mortality among hospitalized inflammatory bowel disease patients","volume":"103","author":"Nguyen","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0040","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1046\/j.1572-0241.2003.04026.x","article-title":"Venous thromboembolism in inflammatory bowel disease","volume":"99","author":"Solem","year":"2004","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0045","doi-asserted-by":"crossref","first-page":"2174","DOI":"10.1002\/ibd.21563","article-title":"Thromboembolism in pediatric inflammatory bowel disease: systematic review","volume":"17","author":"Lazzerini","year":"2011","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0050","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1053\/j.gastro.2010.05.026","article-title":"Inflammatory bowel disease is a risk factor for recurrent venous thromboembolism","volume":"139","author":"Novacek","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0055","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1097\/DCR.0000000000000257","article-title":"Risk of catheter-associated deep venous thrombosis in inflammatory bowel disease","volume":"57","author":"Bhakta","year":"2014","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0060","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1177\/014860710803200188","article-title":"Thromboembolism in infants and children with gastrointestinal failure receiving long-term parenteral nutrition","volume":"32","author":"Kakzanov","year":"2008","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0065","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1097\/DCR.0b013e3182698f60","article-title":"Venous thromboembolism after surgery for inflammatory bowel disease: are there modifiable risk factors? Data from ACS NSQIP","volume":"55","author":"Wallaert","year":"2012","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0070","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1002\/ibd.21334","article-title":"Thrombosis and inflammatory bowel disease: a call for improved awareness and prevention","volume":"17","author":"Zitomersky","year":"2011","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0075","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1182\/blood.V83.5.1251.1251","article-title":"Venous thromboembolic complications (VTE) in children: first analyses of the Canadian Registry of VTE","volume":"83","author":"Andrew","year":"1994","journal-title":"Blood"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0080","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1067\/mpd.2001.118192","article-title":"Venous thromboembolism in childhood: a prospective two-year registry in The Netherlands","volume":"139","author":"van Ommen","year":"2001","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0085","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1542\/peds.2015-1386","article-title":"Costs of venous thromboembolism, catheter-associated urinary tract infection, and pressure ulcer","volume":"136","author":"Goudie","year":"2015","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0090","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1378\/chest.113.1.165","article-title":"Benefit of heparin in central venous and pulmonary artery catheters: a meta-analysis of randomized controlled trials","volume":"113","author":"Randolph","year":"1998","journal-title":"Chest"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0095","doi-asserted-by":"crossref","first-page":"e195S","DOI":"10.1378\/chest.11-2296","article-title":"Prevention of VTE in nonsurgical patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines","volume":"141","author":"Kahn","year":"2012","journal-title":"Chest"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0100","doi-asserted-by":"crossref","first-page":"381S","DOI":"10.1378\/chest.08-0656","article-title":"Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)","volume":"133","author":"Geerts","year":"2008","journal-title":"Chest"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0105","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1053\/j.gastro.2014.01.042","article-title":"Consensus statements on the risk, prevention, and treatment of venous thromboembolism in inflammatory bowel disease: Canadian Association of Gastroenterology","volume":"146","author":"Nguyen","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0110","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1542\/hpeds.2014-0041","article-title":"The incidence of catheter-associated venous thrombosis in noncritically ill children","volume":"5","author":"Smitherman","year":"2015","journal-title":"Hosp Pediatr"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0115","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1097\/MPG.0b013e31829ce5cd","article-title":"Risk factors, morbidity, and treatment of thrombosis in children and young adults with active inflammatory bowel disease","volume":"57","author":"Zitomersky","year":"2013","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0120","doi-asserted-by":"crossref","DOI":"10.1007\/s11239-017-1532-y","article-title":"The use of natural language processing on pediatric diagnostic radiology reports in the electronic health record to identify deep venous thrombosis in children","author":"Galvez","year":"2017","journal-title":"J Thromb Thrombolysis"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0125","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.thromres.2011.10.032","article-title":"Sensitivity of discharge diagnosis ICD-9 codes for pediatric venous thromboembolism is greater than specificity, but still suboptimal for surveillance and clinical research","volume":"129","author":"Branchford","year":"2012","journal-title":"Thromb Res"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0130","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.jclinepi.2009.09.002","article-title":"ICD-10 hospital discharge diagnosis codes were sensitive for identifying pulmonary embolism but not deep vein thrombosis","volume":"63","author":"Casez","year":"2010","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0135","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0140-6736(13)60592-9","article-title":"Risk of venous thromboembolism associated with peripherally inserted central catheters: a systematic review and meta-analysis","volume":"382","author":"Chopra","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0140","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1182\/blood.V128.22.419.419","article-title":"Determining the incidence and risk factors for central venous catheter related thrombosis in children [abstract]","volume":"128","author":"Jaffray","year":"2016","journal-title":"Blood"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0145","doi-asserted-by":"crossref","first-page":"4197","DOI":"10.1002\/cncr.25199","article-title":"Risk factors for central venous catheter thrombotic complications in children and adolescents with cancer","volume":"116","author":"Revel-Vilk","year":"2010","journal-title":"Cancer"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0150","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1097\/00005176-199904000-00013","article-title":"Coagulation and fibrinolysis in children, adolescents, and young adults with inflammatory bowel disease","volume":"28","author":"Weber","year":"1999","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0155","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1055\/s-0035-1556590","article-title":"Hypercoagulability and platelet abnormalities in inflammatory bowel disease","volume":"41","author":"Senchenkova","year":"2015","journal-title":"Semin Thromb Hemost"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0160","doi-asserted-by":"crossref","first-page":"2388","DOI":"10.1182\/blood-2016-05-716720","article-title":"Thrombosis in the setting of obesity or inflammatory bowel disease","volume":"128","author":"Lentz","year":"2016","journal-title":"Blood"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0165","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1111\/jth.13388","article-title":"Association of thrombophilia and catheter-associated thrombosis in children: a systematic review and meta-analysis","volume":"14","author":"Neshat-Vahid","year":"2016","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0170","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1056\/NEJMc1408861","article-title":"Anticoagulation for central venous catheters in patients with cancer","volume":"371","author":"D'Ambrosio","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0175","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.amjmed.2007.05.010","article-title":"Prevention of central venous catheter-associated thrombosis: a meta-analysis","volume":"120","author":"Kirkpatrick","year":"2007","journal-title":"Am J Med"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0180","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1111\/jth.12598","article-title":"Central venous catheter-related thrombosis and thromboprophylaxis in children: a systematic review and meta-analysis","volume":"12","author":"Vidal","year":"2014","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0185","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0049-3848(03)00099-9","article-title":"An open-label randomized controlled trial of low molecular weight heparin for the prevention of central venous line-related thrombotic complications in children: the PROTEKT trial","volume":"109","author":"Massicotte","year":"2003","journal-title":"Thromb Res"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0190","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1007\/s001340051289","article-title":"Heparin-bonded central venous lines reduce thrombotic and infective complications in critically ill children","volume":"26","author":"Pierce","year":"2000","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0195","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1111\/j.1365-2036.2007.03418.x","article-title":"Meta-analysis: the utility and safety of heparin in the treatment of active ulcerative colitis","volume":"26","author":"Shen","year":"2007","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0200","doi-asserted-by":"crossref","first-page":"e479","DOI":"10.1016\/j.crohns.2013.03.002","article-title":"Predictors and safety of venous thromboembolism prophylaxis among hospitalized inflammatory bowel disease patients","volume":"7","author":"Ra","year":"2013","journal-title":"J Crohns Colitis"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0205","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1542\/peds.2009-0768","article-title":"Dramatic increase in venous thromboembolism in children's hospitals in the United States from 2001 to 2007","volume":"124","author":"Raffini","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0210","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1002\/pbc.23388","article-title":"Pediatric venous thromboembolism in the United States: a tertiary care complication of chronic diseases","volume":"59","author":"Setty","year":"2012","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0215","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.thromres.2015.04.036","article-title":"Development of a new risk score for hospital-associated venous thromboembolism in critically-ill children not undergoing cardiothoracic surgery","volume":"136","author":"Arlikar","year":"2015","journal-title":"Thromb Res"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0220","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.jpeds.2014.05.053","article-title":"Development of a new risk score for hospital-associated venous thromboembolism in noncritically ill children: findings from a large single-institutional case-control study","volume":"165","author":"Atchison","year":"2014","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0225","doi-asserted-by":"crossref","first-page":"178","DOI":"10.4037\/ajcc2012548","article-title":"Early recognition of pediatric venous thromboembolism: a risk-assessment tool","volume":"21","author":"Prentiss","year":"2012","journal-title":"Am J Crit Care"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0230","doi-asserted-by":"crossref","first-page":"e737S","DOI":"10.1378\/chest.11-2308","article-title":"Antithrombotic therapy in neonates and children: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines","volume":"141","author":"Monagle","year":"2012","journal-title":"Chest"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0235","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1378\/chest.10-1944","article-title":"Predictive and associative models to identify hospitalized medical patients at risk for VTE","volume":"140","author":"Spyropoulos","year":"2011","journal-title":"Chest"},{"key":"10.1016\/j.jpeds.2018.02.039_bib0240","doi-asserted-by":"crossref","first-page":"e1326","DOI":"10.1542\/peds.2010-3282","article-title":"Thromboprophylaxis in a pediatric hospital: a patient-safety and quality-improvement initiative","volume":"127","author":"Raffini","year":"2011","journal-title":"Pediatrics"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347618302828?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347618302828?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,10,14]],"date-time":"2019-10-14T01:13:18Z","timestamp":1571015598000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347618302828"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":47,"alternative-id":["S0022347618302828"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2018.02.039","relation":{},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Catheter-Related Venous Thrombosis in Hospitalized Pediatric Patients with Inflammatory Bowel Disease: Incidence, Characteristics, and Role of Anticoagulant Thromboprophylaxis with Enoxaparin","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pediatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpeds.2018.02.039","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}