{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T02:42:55Z","timestamp":1761964975864,"version":"3.40.5"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K23DA038720"],"award-info":[{"award-number":["K23DA038720"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","jpeds.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1016\/j.jpeds.2018.03.048","type":"journal-article","created":{"date-parts":[[2018,5,10]],"date-time":"2018-05-10T05:52:30Z","timestamp":1525931550000},"page":"151-157.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["Outpatient Pharmacotherapy for Neonatal Abstinence Syndrome"],"prefix":"10.1016","volume":"199","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9896-5334","authenticated-orcid":false,"given":"Faouzi I.","family":"Maalouf","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William O.","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James C.","family":"Slaughter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Dudley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6958-0371","authenticated-orcid":false,"given":"Stephen W.","family":"Patrick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2018.03.048_bib0010","first-page":"19","article-title":"Assessment and treatment of abstinence in the infant of the drug-dependent mother","volume":"12","author":"Finnegan","year":"1975","journal-title":"Int J Clin Pharmacol Biopharm"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0015","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1542\/peds.2014-3299","article-title":"Prescription opioid epidemic and infant outcomes","volume":"135","author":"Patrick","year":"2015","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0020","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1038\/jp.2015.36","article-title":"Increasing incidence and geographic distribution of neonatal abstinence syndrome: United States 2009 to 2012","volume":"35","author":"Patrick","year":"2015","journal-title":"J Perinatol"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0025","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1001\/jama.2012.3951","article-title":"Neonatal abstinence syndrome and associated health care expenditures: United States, 2000-2009","volume":"307","author":"Patrick","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0030","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1056\/NEJMsa1500439","article-title":"Increasing incidence of the neonatal abstinence syndrome in U.S. neonatal ICUs","volume":"372","author":"Tolia","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0035","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1542\/hpeds.2012-0079","article-title":"Neonatal abstinence syndrome management from prenatal counseling to postdischarge follow-up care: results of a national survey","volume":"3","author":"Mehta","year":"2013","journal-title":"Hosp Pediatr"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0040","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1046\/j.1440-1754.2001.00657.x","article-title":"Coordinated outpatient care of the narcotic-dependent infant","volume":"37","author":"Oei","year":"2001","journal-title":"J Paediatr Child Health"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0045","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/jp.2011.114","article-title":"Neonatal abstinence syndrome: transitioning methadone-treated infants from an inpatient to an outpatient setting","volume":"32","author":"Backes","year":"2012","journal-title":"J Perinatol"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0050","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1111\/apa.12603","article-title":"Home-based detoxification for neonatal abstinence syndrome reduces length of hospital admission without prolonging treatment","volume":"103","author":"Smirk","year":"2014","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0055","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1089\/pop.2014.0134","article-title":"Neonatal abstinence syndrome: influence of a combined inpatient\/outpatient methadone treatment regimen on the average length of stay of a Medicaid NICU Population","volume":"18","author":"Lee","year":"2015","journal-title":"Popul Health Manage"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0060","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.yebeh.2014.07.010","article-title":"Brief postnatal exposure to phenobarbital impairs passive avoidance learning and sensorimotor gating in rats","volume":"37","author":"Gutherz","year":"2014","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0065","doi-asserted-by":"crossref","first-page":"15089","DOI":"10.1073\/pnas.222550499","article-title":"Antiepileptic drugs and apoptotic neurodegeneration in the developing brain","volume":"99","author":"Bittigau","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0070","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1056\/NEJM199002083220604","article-title":"Phenobarbital for febrile seizures\u2013effects on intelligence and on seizure recurrence","volume":"322","author":"Farwell","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0075","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.1056\/NEJMoa055202","article-title":"Major congenital malformations after first-trimester exposure to ACE inhibitors","volume":"354","author":"Cooper","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0080","doi-asserted-by":"crossref","first-page":"E80","DOI":"10.1111\/j.1440-1754.2012.02471.x","article-title":"Profile of infants born to drug-using mothers: a state-wide audit","volume":"49","author":"Abdel-Latif","year":"2013","journal-title":"J Paediatr Child Health"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0085","doi-asserted-by":"crossref","first-page":"F249","DOI":"10.1136\/adc.2008.152769","article-title":"Management of neonatal abstinence syndrome: a national survey and review of practice","volume":"94","author":"O'Grady","year":"2009","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0090","doi-asserted-by":"crossref","first-page":"e811","DOI":"10.1542\/peds.2014-2767","article-title":"Reasons for rehospitalization in children who had neonatal abstinence syndrome","volume":"136","author":"Uebel","year":"2015","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0095","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1542\/hpeds.2015-0024","article-title":"Risk of hospital readmission among infants with neonatal abstinence syndrome","volume":"5","author":"Patrick","year":"2015","journal-title":"Hosp Pediatr"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0100","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1089\/pop.2016.0158","article-title":"Potential for Medicaid savings: a state and national comparison of an innovative neonatal abstinence syndrome treatment model","volume":"20","author":"Dickes","year":"2017","journal-title":"Popul Health Manage"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0105","doi-asserted-by":"crossref","first-page":"e803","DOI":"10.1542\/peds.2015-1141","article-title":"Implementation of a neonatal abstinence syndrome weaning protocol: a multicenter cohort study","volume":"136","author":"Hall","year":"2015","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0110","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2015-3835","article-title":"Improving care for neonatal abstinence syndrome","volume":"137","author":"Patrick","year":"2016","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0115","doi-asserted-by":"crossref","first-page":"e20152929","DOI":"10.1542\/peds.2015-2929","article-title":"Rooming-in to treat neonatal abstinence syndrome: improved family-centered care at lower cost","volume":"137","author":"Holmes","year":"2016","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2018.03.048_bib0120","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1056\/NEJMoa1110212","article-title":"ADHD drugs and serious cardiovascular events in children and young adults","volume":"365","author":"Cooper","year":"2011","journal-title":"N Engl J Med"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347618304207?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347618304207?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,21]],"date-time":"2018-08-21T16:21:32Z","timestamp":1534868492000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347618304207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":23,"alternative-id":["S0022347618304207"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2018.03.048","relation":{},"ISSN":["0022-3476"],"issn-type":[{"type":"print","value":"0022-3476"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Outpatient Pharmacotherapy for Neonatal Abstinence Syndrome","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pediatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpeds.2018.03.048","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}