{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T23:22:55Z","timestamp":1790292175495,"version":"4.1.0"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["R01HD071981"],"award-info":[{"award-number":["R01HD071981"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR000003"],"award-info":[{"award-number":["UL1TR000003"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR001876"],"award-info":[{"award-number":["UL1TR001876"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpeds.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.jpeds.2019.04.059","type":"journal-article","created":{"date-parts":[[2019,6,11]],"date-time":"2019-06-11T18:38:36Z","timestamp":1560278316000},"page":"79-86.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Cross-Sectional Study of Arterial Stiffness in Adolescents with Down Syndrome"],"prefix":"10.1016","volume":"212","author":[{"given":"Andrea","family":"Kelly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheela N.","family":"Magge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1170-6028","authenticated-orcid":false,"given":"Rachel","family":"Walega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Cochrane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E.","family":"Pipan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babette S.","family":"Zemel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meryl S.","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel S.","family":"Gidding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ray","family":"Townsend","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2019.04.059_bib1","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1034\/j.1399-0004.2002.620506.x","article-title":"The changing survival profile of people with Down's syndrome: implications for genetic counselling","volume":"62","author":"Glasson","year":"2002","journal-title":"Clin Genet"},{"key":"10.1016\/j.jpeds.2019.04.059_bib2","doi-asserted-by":"crossref","first-page":"e1204","DOI":"10.1542\/peds.2015-1652","article-title":"Growth charts for children with Down syndrome in the United States","volume":"136","author":"Zemel","year":"2015","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2019.04.059_bib3","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.ridd.2011.09.022","article-title":"Overweight and obesity in older people with intellectual disability","volume":"33","author":"de Winter","year":"2012","journal-title":"Res Dev Disabil"},{"key":"10.1016\/j.jpeds.2019.04.059_bib4","doi-asserted-by":"crossref","first-page":"e0137093","DOI":"10.1371\/journal.pone.0137093","article-title":"Risk of major cardiovascular events in people with Down syndrome","volume":"10","author":"Sobey","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jpeds.2019.04.059_bib5","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.116.004979","article-title":"Microvascular function contributes to the relation between aortic stiffness and cardiovascular events: the Framingham Heart Study","volume":"9","author":"Cooper","year":"2016","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.jpeds.2019.04.059_bib6","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.jacc.2013.09.063","article-title":"Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects","volume":"63","author":"Ben-Shlomo","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jpeds.2019.04.059_bib7","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1161\/HYPERTENSIONAHA.116.07653","article-title":"Vascular stiffness in children with chronic kidney disease","volume":"69","author":"Savant","year":"2017","journal-title":"Hypertension"},{"key":"10.1016\/j.jpeds.2019.04.059_bib8","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1097\/HJH.0b013e32833a6132","article-title":"Increased arterial stiffness is found in adolescents with obesity or obesity-related type 2 diabetes mellitus","volume":"28","author":"Urbina","year":"2010","journal-title":"J Hypertens"},{"key":"10.1016\/j.jpeds.2019.04.059_bib9","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.jpeds.2009.11.011","article-title":"Prevalence of increased arterial stiffness in children with type 1 diabetes mellitus differs by measurement site and sex: the SEARCH for Diabetes in Youth Study","volume":"156","author":"Urbina","year":"2010","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2019.04.059_bib10","doi-asserted-by":"crossref","first-page":"881","DOI":"10.2337\/dc09-0747","article-title":"Measures of arterial stiffness in youth with type 1 and type 2 diabetes: the SEARCH for diabetes in youth study","volume":"33","author":"Wadwa","year":"2010","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jpeds.2019.04.059_bib11","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1007\/s10554-015-0827-3","article-title":"Serial assessment of arterial structure and function in patients with coarctation of the aorta undergoing stenting","volume":"32","author":"Jesus","year":"2016","journal-title":"Int J Cardiovasc Imaging"},{"key":"10.1016\/j.jpeds.2019.04.059_bib12","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.1016\/S0735-1097(03)00480-7","article-title":"Ambulatory blood pressure, left ventricular mass, and conduit artery function late after successful repair of coarctation of the aorta","volume":"41","author":"de Divitiis","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jpeds.2019.04.059_bib13","doi-asserted-by":"crossref","first-page":"I165","DOI":"10.1161\/hc37t1.094900","article-title":"Vascular dysfunction after repair of coarctation of the aorta: impact of early surgery","volume":"104","author":"de Divitiis","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.jpeds.2019.04.059_bib14","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1016\/j.amjcard.2014.09.032","article-title":"Comparison by magnetic resonance phase contrast imaging of pulse-wave velocity in patients with single ventricle who have reconstructed aortas versus those without","volume":"114","author":"Fogel","year":"2014","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jpeds.2019.04.059_bib15","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1161\/HYPERTENSIONAHA.110.152686","article-title":"Reference values of pulse wave velocity in healthy children and teenagers","volume":"56","author":"Reusz","year":"2010","journal-title":"Hypertension"},{"key":"10.1016\/j.jpeds.2019.04.059_bib16","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jpeds.2015.12.042","article-title":"Assessment of left ventricular mass in children and adolescents: current status","volume":"170","author":"Gidding","year":"2016","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2019.04.059_bib17","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1001\/archinte.161.11.1413","article-title":"Non-high-density lipoprotein cholesterol level as a predictor of cardiovascular disease mortality","volume":"161","author":"Cui","year":"2001","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.jpeds.2019.04.059_bib18","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.1161\/01.CIR.0000038496.57570.06","article-title":"Non-high-density lipoprotein cholesterol levels predict five-year outcome in the Bypass Angioplasty Revascularization Investigation (BARI)","volume":"106","author":"Bittner","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.jpeds.2019.04.059_bib19","doi-asserted-by":"crossref","first-page":"16","DOI":"10.2337\/diacare.26.1.16","article-title":"Non-HDL cholesterol as a predictor of cardiovascular disease in type 2 diabetes: the strong heart study","volume":"26","author":"Lu","year":"2003","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jpeds.2019.04.059_bib20","doi-asserted-by":"crossref","first-page":"6","DOI":"10.5551\/jat.11.6","article-title":"Non-HDL cholesterol as a measure of atherosclerotic risk","volume":"11","author":"Packard","year":"2004","journal-title":"J Atheroscler Thromb"},{"key":"10.1016\/j.jpeds.2019.04.059_bib21","first-page":"1","article-title":"2000 CDC Growth Charts for the United States: methods and development","volume":"11","author":"Kuczmarski","year":"2002","journal-title":"Vital Health Stat"},{"key":"10.1016\/j.jpeds.2019.04.059_bib22","series-title":"Growth at Adolescence neOBSP. Growth at adolescence","author":"Tanner","year":"1962"},{"key":"10.1016\/j.jpeds.2019.04.059_bib23","first-page":"61","article-title":"Testicular volume during adolescence. Cross-sectional and longitudinal studies","volume":"29","author":"Zachmann","year":"1974","journal-title":"Helv Paediatr Acta"},{"key":"10.1016\/j.jpeds.2019.04.059_bib24","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/BF02088471","article-title":"Validation of a self-administered instrument to assess stage of adolescent development","volume":"9","author":"Morris","year":"1980","journal-title":"J Youth Adolesc"},{"key":"10.1016\/j.jpeds.2019.04.059_bib25","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1161\/01.HYP.0000150859.47929.8e","volume":"45","author":"Pickering","year":"2005","journal-title":"Hypertension"},{"key":"10.1016\/j.jpeds.2019.04.059_bib26","first-page":"555","article-title":"The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents","volume":"114","year":"2005","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2019.04.059_bib27","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1097\/HJH.0b013e32834fa8b0","article-title":"Expert consensus document on the measurement of aortic stiffness in daily practice using carotid-femoral pulse wave velocity","volume":"30","author":"Van Bortel","year":"2012","journal-title":"J Hypertens"},{"key":"10.1016\/j.jpeds.2019.04.059_bib28","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1161\/HYPERTENSIONAHA.109.192639","article-title":"Noninvasive assessment of subclinical atherosclerosis in children and adolescents: recommendations for standard assessment for clinical research: a scientific statement from the American Heart Association","volume":"54","author":"Urbina","year":"2009","journal-title":"Hypertension"},{"key":"10.1016\/j.jpeds.2019.04.059_bib29","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1016\/j.jacc.2009.10.061","article-title":"Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis","volume":"55","author":"Vlachopoulos","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jpeds.2019.04.059_bib30","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1161\/HYP.0000000000000033","article-title":"Recommendations for improving and standardizing vascular research on arterial stiffness: a scientific statement from the American Heart Association","volume":"66","author":"Townsend","year":"2015","journal-title":"Hypertension"},{"key":"10.1016\/j.jpeds.2019.04.059_bib31","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/jch.12574","article-title":"Clinical use of pulse wave analysis: proceedings from a symposium sponsored by North American Artery","volume":"17","author":"Townsend","year":"2015","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"10.1016\/j.jpeds.2019.04.059_bib32","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/pedi.12017","article-title":"Arterial compliance is increased in children with type 2 diabetes compared with normal weight peers but not obese peers","volume":"14","author":"Tryggestad","year":"2013","journal-title":"Pediatr Diabetes"},{"key":"10.1016\/j.jpeds.2019.04.059_bib33","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1161\/HYPERTENSIONAHA.118.11434","article-title":"SHIP-AHOY (Study of High Blood Pressure in Pediatrics: Adult Hypertension Onset in Youth)","volume":"72","author":"Mendizabal","year":"2018","journal-title":"Hypertension"},{"key":"10.1016\/j.jpeds.2019.04.059_bib34","doi-asserted-by":"crossref","first-page":"375","DOI":"10.2147\/VHRM.S21273","article-title":"Stiffness of the large arteries in individuals with and\u00a0without Down syndrome","volume":"7","author":"Rodrigues","year":"2011","journal-title":"Vasc Health Risk Manag"},{"key":"10.1016\/j.jpeds.2019.04.059_bib35","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1093\/eurheartj\/ehq165","article-title":"Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: 'establishing normal and reference values'","volume":"31","author":"Reference Values for Arterial Stiffness Collaboration","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jpeds.2019.04.059_bib36","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1016\/j.amjcard.2010.06.079","article-title":"Comparison of intima-media thickness of the carotid artery and cardiovascular disease risk factors in adults with versus without the Down syndrome","volume":"106","author":"Draheim","year":"2010","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jpeds.2019.04.059_bib37","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1161\/CIRCULATIONAHA.109.914507","article-title":"Hemodynamic correlates of blood pressure across the adult age spectrum: noninvasive evaluation in the Framingham Heart Study","volume":"122","author":"Mitchell","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jpeds.2019.04.059_bib38","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1161\/01.HYP.28.4.569","article-title":"Low blood pressure in Down's syndrome, A link with Alzheimer's disease?","volume":"28","author":"Morrison","year":"1996","journal-title":"Hypertension"},{"key":"10.1016\/j.jpeds.2019.04.059_bib39","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1590\/1516-3180.2016.0057180316","article-title":"Blood pressure levels and body mass index in Brazilian adults with Down syndrome","volume":"134","author":"Pucci","year":"2016","journal-title":"Sao Paulo Med J"},{"key":"10.1016\/j.jpeds.2019.04.059_bib40","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1161\/HYPERTENSIONAHA.106.085738","article-title":"Long-term trandolapril treatment is associated with reduced aortic stiffness: the prevention of events with angiotensin-converting enzyme inhibition hemodynamic substudy","volume":"49","author":"Mitchell","year":"2007","journal-title":"Hypertension"},{"key":"10.1016\/j.jpeds.2019.04.059_bib41","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1203\/PDR.0b013e31815b47ff","article-title":"Pulse wave velocity in end-stage renal disease: influence of age and body dimensions","volume":"63","author":"Kis","year":"2008","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jpeds.2019.04.059_bib42","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1056\/NEJMsa060185","article-title":"Chronic health conditions in adult survivors of childhood cancer","volume":"355","author":"Oeffinger","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jpeds.2019.04.059_bib43","doi-asserted-by":"crossref","first-page":"945","DOI":"10.7326\/0003-4819-140-11-200406010-00035","article-title":"The evolving diabetes burden in the United States","volume":"140","author":"Engelgau","year":"2004","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jpeds.2019.04.059_bib44","first-page":"1079","article-title":"Sleep apnea as an independent risk factor for all-cause mortality: the Busselton Health Study","volume":"31","author":"Marshall","year":"2008","journal-title":"Sleep"},{"key":"10.1016\/j.jpeds.2019.04.059_bib45","doi-asserted-by":"crossref","first-page":"e1000132","DOI":"10.1371\/journal.pmed.1000132","article-title":"Sleep-disordered breathing and mortality: a prospective cohort study","volume":"6","author":"Punjabi","year":"2009","journal-title":"PLoS Med"},{"key":"10.1016\/j.jpeds.2019.04.059_bib46","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1164\/rccm.200809-1392OC","article-title":"Alterations in Glucose Disposal in Sleep-disordered Breathing","volume":"179","author":"Punjabi","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.jpeds.2019.04.059_bib47","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.atherosclerosis.2009.08.016","article-title":"The incremental role of obstructive sleep apnoea on markers of atherosclerosis in patients with metabolic syndrome","volume":"208","author":"Drager","year":"2010","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jpeds.2019.04.059_bib48","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.jacc.2013.05.045","article-title":"Obstructive sleep\u00a0apnea: a cardiometabolic risk in obesity and the metabolic syndrome","volume":"62","author":"Drager","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jpeds.2019.04.059_bib49","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1378\/chest.06-2703","article-title":"Obstructive sleep apnea, hypertension, and their interaction on\u00a0arterial stiffness and heart remodeling","volume":"131","author":"Drager","year":"2007","journal-title":"Chest"},{"key":"10.1016\/j.jpeds.2019.04.059_bib50","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1038\/ajh.2009.246","article-title":"Obstructive sleep apnea, masked hypertension, and arterial stiffness in men","volume":"23","author":"Drager","year":"2010","journal-title":"Am J Hypertens"},{"key":"10.1016\/j.jpeds.2019.04.059_bib51","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1111\/jch.13008","article-title":"Association of obstructive sleep apnea with arterial stiffness and nondipping blood pressure in patients with hypertension","volume":"19","author":"Jenner","year":"2017","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"10.1016\/j.jpeds.2019.04.059_bib52","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3104\/reports.138","article-title":"Sleep related breathing disorders in adults with Down\u00a0syndrome","volume":"8","author":"Resta","year":"2003","journal-title":"Downs Syndr Res Pract"},{"key":"10.1016\/j.jpeds.2019.04.059_bib53","doi-asserted-by":"crossref","first-page":"317","DOI":"10.5664\/jcsm.27541","article-title":"Obstructive sleep apnea in adults with Down syndrome","volume":"5","author":"Trois","year":"2009","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.jpeds.2019.04.059_bib54","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0278-2626(02)00019-2","article-title":"Cognitive status in Down syndrome individuals with sleep\u00a0disordered breathing deficits (SDB)","volume":"50","author":"Andreou","year":"2002","journal-title":"Brain Cogn"},{"key":"10.1016\/j.jpeds.2019.04.059_bib55","doi-asserted-by":"crossref","first-page":"e91","DOI":"10.1183\/20734735.012116","article-title":"Obstructive sleep apnoea\/hypopnoea syndrome in adults with\u00a0Down syndrome","volume":"12","author":"Hill","year":"2016","journal-title":"Breathe (Sheff)"},{"key":"10.1016\/j.jpeds.2019.04.059_bib56","series-title":"Global recommendations on physical activity for health","author":"World Health Organization","year":"2010"},{"key":"10.1016\/j.jpeds.2019.04.059_bib57","series-title":"Physical activity guidelines for Americans","year":"2008"},{"key":"10.1016\/j.jpeds.2019.04.059_bib58","first-page":"1151","article-title":"Physical activity and cardiorespiratory fitness in adolescents with Down syndrome","volume":"28","author":"Matute-Llorente","year":"2013","journal-title":"Nutr Hosp"},{"key":"10.1016\/j.jpeds.2019.04.059_bib59","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.ridd.2013.11.026","article-title":"Objective assessment of sedentary time and physical\u00a0activity throughout the week in adolescents with Down syndrome. The UP&DOWN study","volume":"35","author":"Izquierdo-Gomez","year":"2014","journal-title":"Res Dev Disabil"},{"key":"10.1016\/j.jpeds.2019.04.059_bib60","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1177\/000992289203100605","article-title":"Dietary practices, physical activity, and body-mass index in a selected population of Down syndrome children and their siblings","volume":"31","author":"Sharav","year":"1992","journal-title":"Clin Pediatr (Phila)"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347619305426?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347619305426?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T05:27:53Z","timestamp":1777440473000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347619305426"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":60,"alternative-id":["S0022347619305426"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2019.04.059","relation":{},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cross-Sectional Study of Arterial Stiffness in Adolescents with Down Syndrome","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pediatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpeds.2019.04.059","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}