{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:59:17Z","timestamp":1786993157622,"version":"build-2736575974"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Charles Woodson Pediatric Research Fund"},{"DOI":"10.13039\/100006093","name":"PCORI","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006093","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010621","name":"Pediatric Epilepsy Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010621","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpeds.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1016\/j.jpeds.2020.01.066","type":"journal-article","created":{"date-parts":[[2020,3,25]],"date-time":"2020-03-25T16:26:32Z","timestamp":1585153592000},"page":"81-87.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"special_numbering":"C","title":["Early Electroencephalogram Background Could Guide Tailored Duration of Monitoring for Neonatal Encephalopathy Treated with Therapeutic Hypothermia"],"prefix":"10.1016","volume":"221","author":[{"given":"Giulia M.","family":"Benedetti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca J.","family":"Vartanian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harlan","family":"McCaffery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9e A.","family":"Shellhaas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2020.01.066_bib1","doi-asserted-by":"crossref","first-page":"e1400","DOI":"10.1542\/peds.2010-2972E","article-title":"Neonatal resuscitation: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care","volume":"126","author":"Kattwinkel","year":"2010","journal-title":"Pediatrics"},{"issue":"16 Suppl 2","key":"10.1016\/j.jpeds.2020.01.066_bib2","first-page":"S516","article-title":"Part 11: Neonatal resuscitation: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with treatment recommendations","volume":"122","author":"Perlman","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.jpeds.2020.01.066_bib3","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.jpeds.2009.03.040","article-title":"Clinical neonatal seizures are independently associated with outcome in infants at risk for hypoxic-ischemic brain injury","volume":"155","author":"Glass","year":"2009","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2020.01.066_bib4","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1212\/WNL.0000000000000282","article-title":"Risk factors for EEG seizures in neonates treated with hypothermia: a multicenter cohort study","volume":"82","author":"Glass","year":"2014","journal-title":"Neurology"},{"key":"10.1016\/j.jpeds.2020.01.066_bib5","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1111\/dmcn.13215","article-title":"Seizure burden and neurodevelopmental outcome in neonates with hypoxic-ischemic encephalopathy","volume":"58","author":"Kharoshankaya","year":"2016","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib6","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1177\/0883073810390036","article-title":"Electrographic seizures during therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy","volume":"26","author":"Wusthoff","year":"2011","journal-title":"J Child Neurol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib7","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1097\/WNP.0b013e31823e96d7","article-title":"The American Clinical Neurophysiology Society's Guideline on continuous electroencephalography monitoring in neonates","volume":"28","author":"Shellhaas","year":"2011","journal-title":"J Clin Neurophysiol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib8","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1038\/jp.2017.153","article-title":"Cooling in neonatal hypoxic-ischemic encephalopathy: practices and opinions on minimum standards in the state of California","volume":"38","author":"Wusthoff","year":"2018","journal-title":"J Perinatol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib9","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1111\/epi.12331","article-title":"Hypothermia for pediatric refractory status epilepticus","volume":"54","author":"Guilliams","year":"2013","journal-title":"Epilepsia"},{"key":"10.1016\/j.jpeds.2020.01.066_bib10","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/ana.10402","article-title":"Head cooling with mild systemic hypothermia in anesthetized piglets is neuroprotective","volume":"53","author":"Tooley","year":"2003","journal-title":"Ann Neurol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib11","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1001\/archneur.1969.00480100106015","article-title":"Inhibition of focal seizures by moderate hypothermia. A clinical and experimental study","volume":"20","author":"Vastola","year":"1969","journal-title":"Arch Neurol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib12","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.jpeds.2013.01.041","article-title":"Therapeutic hypothermia in neonatal hypoxic ischemic encephalopathy: electrographic seizures and magnetic resonance imaging evidence of injury","volume":"163","author":"Srinivasakumar","year":"2013","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2020.01.066_bib13","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1542\/peds.2004-1695","article-title":"Rebound seizures during rewarming","volume":"114","author":"Battin","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2020.01.066_bib14","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.seizure.2015.10.007","article-title":"The temporal characteristics of seizures in neonatal hypoxic ischemic encephalopathy treated with hypothermia","volume":"33","author":"Lynch","year":"2015","journal-title":"Seizure"},{"key":"10.1016\/j.jpeds.2020.01.066_bib15","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1056\/NEJMcps050929","article-title":"Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy","volume":"353","author":"Shankaran","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jpeds.2020.01.066_bib16","first-page":"371","article-title":"The ten-twenty electrode system of the International Federation","volume":"10","author":"Jasper","year":"1958","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib17","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1080\/1086508X.2006.11079577","article-title":"Guideline two: Minimum technical standards for pediatric electroencephalography","volume":"46","year":"2006","journal-title":"Am J Electroneurodiagnostic Technol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib18","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1097\/WNP.0b013e3182872b24","article-title":"American Clinical Neurophysiology Society standardized EEG terminology and categorization for the description of continuous EEG monitoring in neonates: report of the American Clinical Neurophysiology Society critical care monitoring committee","volume":"30","author":"Tsuchida","year":"2013","journal-title":"J Clin Neurophysiol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib19","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1542\/peds.107.3.461","article-title":"Combined use of electroencephalogram and magnetic resonance imaging in full-term neonates with acute encephalopathy","volume":"107","author":"Biagioni","year":"2001","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2020.01.066_bib20","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/s41390-018-0040-x","article-title":"Predictive value of early EEG for seizures in neonates with hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia","volume":"84","author":"Cornet","year":"2018","journal-title":"Pediatr Res"},{"key":"10.1016\/j.jpeds.2020.01.066_bib21","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/j.1528-1157.1998.tb01418.x","article-title":"EEG background as predictor of electrographic seizures in high-risk neonates","volume":"39","author":"Laroia","year":"1998","journal-title":"Epilepsia"},{"key":"10.1016\/j.jpeds.2020.01.066_bib22","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.pediatrneurol.2016.10.019","article-title":"Prediction of neonatal seizures in hypoxic-ischemic encephalopathy using electroencephalograph power analyses","volume":"67","author":"Jain","year":"2017","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib23","doi-asserted-by":"crossref","first-page":"F219","DOI":"10.1136\/archdischild-2013-305206","article-title":"Electrographic seizures are associated with brain injury in newborns undergoing therapeutic hypothermia","volume":"99","author":"Shah","year":"2014","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.jpeds.2020.01.066_bib24","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.clp.2013.10.005","article-title":"Mechanisms of hypothermic neuroprotection","volume":"41","author":"Drury","year":"2014","journal-title":"Clin Perinatol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib25","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1755-5949.2010.00168.x","article-title":"Hypothermia reduces brain edema, spontaneous recurrent seizure attack, and learning memory deficits in the kainic acid treated rats","volume":"17","author":"Wang","year":"2011","journal-title":"CNS Neurosci Ther"},{"key":"10.1016\/j.jpeds.2020.01.066_bib26","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.2741\/4025","article-title":"Effects of hypothermia on brain injury induced by status epilepticus","volume":"17","author":"Zhou","year":"2012","journal-title":"Front Biosci (Landmark Ed)"},{"key":"10.1016\/j.jpeds.2020.01.066_bib27","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.siny.2015.01.001","article-title":"Seizures and hypothermia: importance of electroencephalographic monitoring and considerations for treatment","volume":"20","author":"Boylan","year":"2015","journal-title":"Semin Fetal Neonatal Med"},{"key":"10.1016\/j.jpeds.2020.01.066_bib28","doi-asserted-by":"crossref","first-page":"F267","DOI":"10.1136\/archdischild-2011-300716","article-title":"Cooling and seizure burden in term neonates: an observational study","volume":"97","author":"Low","year":"2012","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.jpeds.2020.01.066_bib29","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.clp.2006.06.004","article-title":"Prolonged electroencephalogram monitoring for seizures and their treatment","volume":"33","author":"Clancy","year":"2006","journal-title":"Clin Perinatol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib30","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.jpeds.2008.03.004","article-title":"Assessment of neonatal electroencephalography (EEG) background by conventional and two amplitude-integrated EEG classification systems","volume":"153","author":"Shellhaas","year":"2008","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2020.01.066_bib31","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/0013-4694(80)90402-2","article-title":"Behavioral state cycles, background EEGs and prognosis of newborns with perinatal hypoxia","volume":"49","author":"Watanabe","year":"1980","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib32","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1097\/00004691-198504000-00002","article-title":"Neonatal polygraphy in full-term and premature infants: a review of normal and abnormal findings","volume":"2","author":"Lombroso","year":"1985","journal-title":"J Clin Neurophysiol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib33","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1016\/j.clinph.2015.12.013","article-title":"Rewarming affects EEG background in term newborns with hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia","volume":"127","author":"Birca","year":"2016","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib34","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1016\/j.clinph.2010.12.059","article-title":"Quantitative EEG analysis in neonatal hypoxic ischaemic encephalopathy","volume":"122","author":"Korotchikova","year":"2011","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.jpeds.2020.01.066_bib35","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.seizure.2015.09.014","article-title":"Amplitude-integrated EEG for detection of neonatal seizures: a systematic review","volume":"33","author":"Rakshasbhuvankar","year":"2015","journal-title":"Seizure"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347620301396?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347620301396?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T09:04:21Z","timestamp":1758359061000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347620301396"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":35,"alternative-id":["S0022347620301396"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2020.01.066","relation":{},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2020,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early Electroencephalogram Background Could Guide Tailored Duration of Monitoring for Neonatal Encephalopathy Treated with Therapeutic Hypothermia","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pediatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpeds.2020.01.066","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}