{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:35:09Z","timestamp":1792812909344,"version":"4.5.0"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpeds.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.jpeds.2021.04.019","type":"journal-article","created":{"date-parts":[[2021,4,19]],"date-time":"2021-04-19T15:43:56Z","timestamp":1618847036000},"page":"149-155.e2","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Growth in Children with a Fontan Circulation"],"prefix":"10.1016","volume":"235","author":[{"given":"Edna E.","family":"Mancilla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1052-9736","authenticated-orcid":false,"given":"Benjamin","family":"Zielonka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey D.","family":"Roizen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn M.","family":"Dodds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth B.","family":"Rand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer R.","family":"Heimall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feiyan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Goldberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Rychik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2021.04.019_bib1","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1016\/S0735-1097(02)01886-7","article-title":"The incidence of congenital heart disease","volume":"39","author":"Hoffman","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jpeds.2021.04.019_bib2","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.jtcvs.2017.01.056","article-title":"Long-term survival after the Fontan operation: twenty years of experience at a single center","volume":"154","author":"Downing","year":"2017","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jpeds.2021.04.019_bib3","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1016\/j.jacc.2015.07.065","article-title":"40-year follow-up after the Fontan operation: long-term outcomes of 1,052 patients","volume":"66","author":"Pundi","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jpeds.2021.04.019_bib4","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1053\/j.pcsu.2015.11.006","article-title":"The relentless effects of the Fontan paradox","volume":"19","author":"Rychik","year":"2016","journal-title":"Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu"},{"key":"10.1016\/j.jpeds.2021.04.019_bib5","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1111\/apa.15098","article-title":"Providing a framework of principles for conceptualising the Fontan circulation","volume":"109","author":"Gewillig","year":"2020","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.jpeds.2021.04.019_bib6","doi-asserted-by":"crossref","first-page":"e004809","DOI":"10.1161\/JAHA.116.004809","article-title":"Hepatic fibrosis is universal following Fontan operation, and severity is associated with time from surgery: a liver biopsy and hemodynamic study","volume":"6","author":"Goldberg","year":"2017","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.jpeds.2021.04.019_bib7","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1016\/j.amjcard.2017.03.004","article-title":"Effect of Fontan-associated morbidities on survival with intact Fontan circulation","volume":"119","author":"Allen","year":"2017","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.jpeds.2021.04.019_bib8","doi-asserted-by":"crossref","first-page":"e234","DOI":"10.1161\/CIR.0000000000000696","article-title":"Evaluation and management of the child and adult with Fontan circulation: a scientific statement from the American Heart Association","volume":"140","author":"Rychik","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.jpeds.2021.04.019_bib9","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1016\/j.jacc.2007.07.050","article-title":"Somatic growth in children with single ventricle physiology impact of physiologic state","volume":"50","author":"Vogt","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jpeds.2021.04.019_bib10","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1136\/heart.89.11.1340","article-title":"Long term somatic growth after repair of tetralogy of Fallot: evidence for restoration of genetic growth potential","volume":"89","author":"Cheung","year":"2003","journal-title":"Heart"},{"key":"10.1016\/j.jpeds.2021.04.019_bib11","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.jacc.2008.02.081","article-title":"A cross-sectional study of exercise performance during the first 2 decades of life after the Fontan operation","volume":"52","author":"Paridon","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.jpeds.2021.04.019_bib12","first-page":"1","article-title":"2000 CDC Growth Charts for the United States: methods and development","volume":"11","author":"Kuczmarski","year":"2002","journal-title":"Vital Health Stat"},{"key":"10.1016\/j.jpeds.2021.04.019_bib13","first-page":"13","article-title":"Multiple imputation for the fatal accident reporting system","volume":"40","author":"Heitjan","year":"1991","journal-title":"J Roy Stat Soc C"},{"key":"10.1016\/j.jpeds.2021.04.019_bib14","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1111\/j.1747-0803.2008.00206.x","article-title":"Somatic growth after fontan and mustard palliation","volume":"3","author":"Hasan","year":"2008","journal-title":"Congenit Heart Dis"},{"key":"10.1016\/j.jpeds.2021.04.019_bib15","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/S0022-5223(97)70184-3","article-title":"Functional outcome after the Fontan operation: factors influencing late morbidity","volume":"114","author":"Gentles","year":"1997","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jpeds.2021.04.019_bib16","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/apa.12032","article-title":"Somatic growth in 94 single ventricle children\u2014comparing systemic right and left ventricle patients","volume":"102","author":"Hessel","year":"2013","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.jpeds.2021.04.019_bib17","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1017\/S1047951100008118","article-title":"Somatic growth failure after the Fontan operation","volume":"10","author":"Cohen","year":"2000","journal-title":"Cardiol Young"},{"key":"10.1016\/j.jpeds.2021.04.019_bib18","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/chd.12597","article-title":"Delayed puberty and abnormal anthropometry and its associations with quality of life in young Fontan survivors: a multicenter cross-sectional study","volume":"13","author":"Menon","year":"2018","journal-title":"Congenit Heart Dis"},{"key":"10.1016\/j.jpeds.2021.04.019_bib19","doi-asserted-by":"crossref","first-page":"e139","DOI":"10.1093\/ejcts\/ezs194","article-title":"Univentricular heart and Fontan staging: analysis of factors impacting on body growth","volume":"41","author":"Francois","year":"2012","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.jpeds.2021.04.019_bib20","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.athoracsur.2009.09.063","article-title":"Use of oral budesonide in the management of protein-losing enteropathy after the Fontan operation","volume":"89","author":"Thacker","year":"2010","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.jpeds.2021.04.019_bib21","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/j.jtcvs.2017.10.047","article-title":"Super-Fontan: Is it possible?","volume":"155","author":"Cordina","year":"2018","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.jpeds.2021.04.019_bib22","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/s00246-019-02248-3","article-title":"Evidence of systemic absorption of enteral budesonide in patients with Fontan-associated protein-losing enteropathy","volume":"41","author":"Roberts","year":"2020","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.jpeds.2021.04.019_bib23","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1017\/S1047951116000093","article-title":"Abnormalities in serum biomarkers correlate with lower cardiac index in the Fontan population","volume":"27","author":"Marino","year":"2017","journal-title":"Cardiol Young"},{"key":"10.1016\/j.jpeds.2021.04.019_bib24","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/s00246-008-9292-2","article-title":"Serum alkaline phosphatase reflects post-Fontan hemodynamics in children","volume":"30","author":"Chin","year":"2009","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.jpeds.2021.04.019_bib25","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1017\/S1047951115001444","article-title":"Low serum 25-hydroxyvitamin D levels and secondary hyperparathyroidism in Fontan patients","volume":"26","author":"Holler","year":"2016","journal-title":"Cardiol Young"},{"key":"10.1016\/j.jpeds.2021.04.019_bib26","doi-asserted-by":"crossref","first-page":"e4810","DOI":"10.1097\/MD.0000000000004810","article-title":"Parathyroid hormone and risk of heart failure in the general population: a meta-analysis of prospective studies","volume":"95","author":"Meng","year":"2016","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.jpeds.2021.04.019_bib27","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1089\/gtmb.2015.0285","article-title":"Serum parathyroid hormone levels predict discharge and readmission for heart failure","volume":"20","author":"Wu","year":"2016","journal-title":"Genet Test Mol Biomarkers"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347621003450?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347621003450?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T09:10:33Z","timestamp":1758359433000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347621003450"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":27,"alternative-id":["S0022347621003450"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2021.04.019","relation":{},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Growth in Children with a Fontan Circulation","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pediatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpeds.2021.04.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}