{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T14:20:36Z","timestamp":1783002036223,"version":"3.54.5"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpeds.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.jpeds.2021.05.039","type":"journal-article","created":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T23:54:11Z","timestamp":1621554851000},"page":"28-33.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["A New Hour-Specific Serum Bilirubin Nomogram for Neonates \u226535\u00a0Weeks of Gestation"],"prefix":"10.1016","volume":"236","author":[{"given":"Timothy M.","family":"Bahr","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erick","family":"Henry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert D.","family":"Christensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen D.","family":"Minton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinod K.","family":"Bhutani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2021.05.039_bib1","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1503\/cmaj.122117","article-title":"Managing the jaundiced newborn: a persistent challenge","volume":"187","author":"Maisels","year":"2015","journal-title":"Can Med Assoc J"},{"key":"10.1016\/j.jpeds.2021.05.039_bib2","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/s41372-019-0583-7","article-title":"TcB, FFR, phototherapy and the persistent occurrence of kernicterus spectrum disorder","volume":"40","author":"Watchko","year":"2020","journal-title":"J Perinatol"},{"key":"10.1016\/j.jpeds.2021.05.039_bib3","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1542\/peds.103.1.6","article-title":"Predictive ability of a predischarge hour-specific serum bilirubin for subsequent significant hyperbilirubinemia in healthy term and near-term newborns","volume":"103","author":"Bhutani","year":"1999","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2021.05.039_bib4","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1136\/adc.2004.060079","article-title":"Identifying newborns at risk of significant hyperbilirubinaemia: a comparison of two recommended approaches","volume":"90","author":"Keren","year":"2005","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jpeds.2021.05.039_bib5","doi-asserted-by":"crossref","first-page":"e170","DOI":"10.1542\/peds.2006-3499","article-title":"A comparison of alternative risk-assessment strategies for predicting significant neonatal hyperbilirubinemia in term and near-term infants","volume":"121","author":"Keren","year":"2008","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2021.05.039_bib6","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1542\/peds.114.1.297","article-title":"Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation","volume":"114","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2021.05.039_bib7","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1542\/peds.2009-0329","article-title":"Hyperbilirubinemia in the newborn infant \u226535 weeks\u2019 gestation: an update with clarifications","volume":"124","author":"Maisels","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2021.05.039_bib8","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1542\/peds.103.2.493","article-title":"Predicting hyperbilirubinemia in newborns: the importance of timing","volume":"103","author":"Maisels","year":"1999","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2021.05.039_bib9","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1542\/peds.2009-0190","article-title":"Bilirubin screening for normal newborns: a critique of the hour-specific bilirubin nomogram","volume":"124","author":"Fay","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2021.05.039_bib10","doi-asserted-by":"crossref","first-page":"e855","DOI":"10.1542\/peds.2005-1338","article-title":"The effect of instituting a prehospital-discharge newborn bilirubin screening program in an 18-hospital health system","volume":"117","author":"Eggert","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2021.05.039_bib11","doi-asserted-by":"crossref","first-page":"xix","DOI":"10.1016\/j.clp.2015.05.002","article-title":"The expanding evidence base to guide neonatal hematology and transfusion medicine practice","volume":"42","author":"Christensen","year":"2015","journal-title":"Preface. Clin Perinatol"},{"key":"10.1016\/j.jpeds.2021.05.039_bib12","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.clp.2015.04.007","article-title":"Hemolytic disorders causing severe neonatal hyperbilirubinemia","volume":"42","author":"Christensen","year":"2015","journal-title":"Clin Perinatol"},{"key":"10.1016\/j.jpeds.2021.05.039_bib13","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1159\/000489820","article-title":"Hemolysis and glucose-6-phosphate dehydrogenase deficiency-related neonatal hyperbilirubinemia","volume":"114","author":"Kaplan","year":"2018","journal-title":"Neonatology"},{"key":"10.1016\/j.jpeds.2021.05.039_bib14","series-title":"Statistical models in S","year":"1992"},{"key":"10.1016\/j.jpeds.2021.05.039_bib15","series-title":"The design of experiments","author":"Fisher","year":"1974"},{"key":"10.1016\/j.jpeds.2021.05.039_bib16","doi-asserted-by":"crossref","first-page":"225","DOI":"10.2307\/2983647","article-title":"Significance tests which may be applied to samples from any populations. II. The Correlation Coefficient Test","volume":"4","author":"Pitman","year":"1937","journal-title":"Suppl J R Stat Soc"},{"key":"10.1016\/j.jpeds.2021.05.039_bib17","first-page":"199","article-title":"The Neurological sequelae of neonatal hyperbilirubinemia: definitions, diagnosis and treatment of the kernicterus spectrum disorders (KSDs)","volume":"13","author":"Le Pichon","year":"2017","journal-title":"Curr Pediatr Rev"},{"key":"10.1016\/j.jpeds.2021.05.039_bib18","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.siny.2009.12.004","article-title":"Chronic bilirubin encephalopathy: diagnosis and outcome","volume":"15","author":"Shapiro","year":"2010","journal-title":"Semin Fetal Neonatal Med"},{"key":"10.1016\/j.jpeds.2021.05.039_bib19","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1001\/jamapediatrics.2019.3765","article-title":"Avoiding harm from hyperbilirubinemia screening","volume":"173","author":"Watchko","year":"2019","journal-title":"JAMA Pediatr"},{"key":"10.1016\/j.jpeds.2021.05.039_bib20","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1136\/adc.2003.039974","article-title":"Rehospitalisation after birth hospitalisation: patterns among infants of all gestations","volume":"90","author":"Escobar","year":"2005","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jpeds.2021.05.039_bib21","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.siny.2009.11.001","article-title":"Hyperbilirubinemia in African American neonates: clinical issues and current challenges","volume":"15","author":"Watchko","year":"2010","journal-title":"Semin Fetal Neonatal Med"},{"key":"10.1016\/j.jpeds.2021.05.039_bib22","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/j.jpeds.2012.12.092","article-title":"Black race is not protective against hazardous bilirubin levels","volume":"162","author":"Wickremasinghe","year":"2013","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2021.05.039_bib23","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1038\/jp.2016.232","article-title":"Effect of genetic variants of bilirubin metabolism on the degree of hyperbilirubinemia in African-American newborns","volume":"37","author":"Schutzman","year":"2017","journal-title":"J Perinatol"},{"key":"10.1016\/j.jpeds.2021.05.039_bib24","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.mehy.2010.02.017","article-title":"The question of ethnic variability and the Darwinian significance of physiological neonatal jaundice in East Asian populations","volume":"75","author":"Wasser","year":"2010","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.jpeds.2021.05.039_bib25","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1001\/archpedi.156.3.276","article-title":"Neonatal jaundice in Asian, White, and mixed-race infants","volume":"156","author":"Setia","year":"2002","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.jpeds.2021.05.039_bib26","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1038\/s41372-020-00901-x","article-title":"Natural history of early neonatal bilirubinemia: a global perspective","volume":"41","author":"Kaplan","year":"2021","journal-title":"J Perinatol"},{"key":"10.1016\/j.jpeds.2021.05.039_bib27","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.jpeds.2012.08.022","article-title":"Predischarge screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy","volume":"162","author":"Bhutani","year":"2013","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2021.05.039_bib28","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0009-8981(87)90224-5","article-title":"Approved recommendation (1986) on the theory of reference values. Part 1. The concept of reference values","volume":"165","author":"Solberg","year":"1987","journal-title":"Clin Chim Acta Int J Clin Chem"},{"key":"10.1016\/j.jpeds.2021.05.039_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-2423(08)60181-X","article-title":"Reference values","volume":"27","author":"Solberg","year":"1989","journal-title":"Adv Clin Chem"},{"key":"10.1016\/j.jpeds.2021.05.039_bib30","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1001\/jamapediatrics.2019.1194","article-title":"Screening for neonatal hyperbilirubinemia\u2014first do no harm?","volume":"173","author":"Grosse","year":"2019","journal-title":"JAMA Pediatr"},{"key":"10.1016\/j.jpeds.2021.05.039_bib31","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.clp.2016.01.005","article-title":"Phototherapy and the risk of photo-oxidative injury in extremely low birth weight infants","volume":"43","author":"Stevenson","year":"2016","journal-title":"Clin Perinatol"},{"key":"10.1016\/j.jpeds.2021.05.039_bib32","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2015-1354","article-title":"Retrospective cohort study of phototherapy and childhood cancer in northern California","volume":"137","author":"Newman","year":"2016","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2021.05.039_bib33","doi-asserted-by":"crossref","first-page":"e20160687","DOI":"10.1542\/peds.2016-0687","article-title":"Phototherapy and Risk of Type 1 Diabetes","volume":"138","author":"Newman","year":"2016","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2021.05.039_bib34","doi-asserted-by":"crossref","first-page":"e20180648","DOI":"10.1542\/peds.2018-0648","article-title":"Childhood seizures after phototherapy","volume":"142","author":"Newman","year":"2018","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2021.05.039_bib35","doi-asserted-by":"crossref","first-page":"e20180662","DOI":"10.1542\/peds.2018-0662","article-title":"Hyperbilirubinemia, phototherapy, and childhood asthma","volume":"142","author":"Kuzniewicz","year":"2018","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2021.05.039_bib36","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1159\/000505818","article-title":"Improving the bilirubin management program in the newborn nursery: background, aims, and protocol","volume":"117","author":"Bahr","year":"2020","journal-title":"Neonatology"},{"key":"10.1016\/j.jpeds.2021.05.039_bib37","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1542\/peds.78.5.837","article-title":"Normal serum bilirubin levels in the newborn and the effect of breast-feeding","volume":"78","author":"Maisels","year":"1986","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2021.05.039_bib38","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/s00431-007-0533-9","article-title":"Neonatal jaundice and stool production in breast- or formula-fed term infants","volume":"167","author":"Buiter","year":"2008","journal-title":"Eur J Pediatr"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347621004893?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347621004893?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T09:10:53Z","timestamp":1758359453000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347621004893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":38,"alternative-id":["S0022347621004893"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2021.05.039","relation":{},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A New Hour-Specific Serum Bilirubin Nomogram for Neonates \u226535\u00a0Weeks of Gestation","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pediatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpeds.2021.05.039","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}