{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T12:49:57Z","timestamp":1771678197654,"version":"3.50.1"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpeds.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.jpeds.2022.05.043","type":"journal-article","created":{"date-parts":[[2022,5,28]],"date-time":"2022-05-28T01:52:30Z","timestamp":1653702750000},"page":"11-13","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Survival Outcomes of Infants with the Trisomy 13 or Trisomy 18 Syndromes"],"prefix":"10.1016","volume":"247","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6007-8518","authenticated-orcid":false,"given":"John C.","family":"Carey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2022.05.043_bib1","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1097\/MOP.0b013e3283595031","article-title":"Perspectives on the care and management of infants with trisomy 18 and trisomy 13: striving for balance","volume":"24","author":"Carey","year":"2012","journal-title":"Curr Opin Pediatr"},{"key":"10.1016\/j.jpeds.2022.05.043_bib2","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1542\/peds.57.4.487","article-title":"On deciding the care of severely handicapped or dying persons: with particular reference to infants","volume":"57","author":"Duff","year":"1976","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2022.05.043_bib3","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/0140-6736(92)90940-5","article-title":"Avoidance of emergency surgery in newborn infants with trisomy 18","volume":"339","author":"Bos","year":"1992","journal-title":"Lancet"},{"key":"10.1016\/j.jpeds.2022.05.043_bib4","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1002\/ajmg.a.31175","article-title":"Neonatal management of trisomy 18: clinical details of 24 patients receiving intensive treatment","volume":"140A","author":"Kosho","year":"2006","journal-title":"Am J Med Genet Part A"},{"key":"10.1016\/j.jpeds.2022.05.043_bib5","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1002\/ajmg.a.37495","article-title":"Survival of children with trisomy 13 and trisomy 18: a multi-state population-based study","volume":"170A","author":"Meyer","year":"2016","journal-title":"Am J Med Genet Part A"},{"key":"10.1016\/j.jpeds.2022.05.043_bib6","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1001\/jama.2016.9819","article-title":"Survival and surgical interventions for children with trisomy 13 and 18","volume":"316","author":"Nelson","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.jpeds.2022.05.043_bib7","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1002\/ajmg.a.37610","article-title":"Does medical intervention affect outcome in infants with trisomy 18 or trisomy 13?","volume":"170A","author":"Kosho","year":"2016","journal-title":"Amer J Med Genet Part A"},{"key":"10.1016\/j.jpeds.2022.05.043_bib8","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1002\/ajmg.a.61370","article-title":"Emerging evidence that medical and surgical interventions improve survival and outcome in the trisomy 13 and 18 syndromes","volume":"182A","author":"Carey","year":"2020","journal-title":"Am J Med Genet Part A"},{"key":"10.1016\/j.jpeds.2022.05.043_bib9","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1055\/s-0041-1732363","article-title":"Management of children with the trisomy 18 and trisomy 13 syndromes: is there a shift in the paradigm of care?","volume":"38","author":"Carey","year":"2021","journal-title":"Am J Perinatol"},{"key":"10.1016\/j.jpeds.2022.05.043_bib10","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.jpeds.2022.04.010","article-title":"Perinatal outcomes of fetuses and infants diagnosed with trisomy 13 or 18","volume":"247","author":"Cortezzo","year":"2022","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2022.05.043_bib11","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1177\/1049909120985210","article-title":"Clinical course for patients with trisomy 13 and 18 pursuing life-prolonging therapies versus comfort-directed care","volume":"38","author":"Milligan","year":"2020","journal-title":"Am J Hosp Palliat Care"},{"key":"10.1016\/j.jpeds.2022.05.043_bib12","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1002\/ajmg.a.37529","article-title":"Trisomy 18: a single center evaluation of management trends and experience with aggressive obstetric or neonatal intervention","volume":"170A","author":"Subramaniam","year":"2016","journal-title":"Am J Med Genet Part A"},{"key":"10.1016\/j.jpeds.2022.05.043_bib13","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1038\/s41372-021-01111-9","article-title":"Medical and surgical interventions and outcomes for infants with trisomy 18 or trisomy 13 at children\u2019s hospitals neonatal intensive care units (NICUs)","volume":"41","author":"Acharya","year":"2021","journal-title":"J Perinatol"},{"key":"10.1016\/j.jpeds.2022.05.043_bib14","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1002\/ajmg.a.62605","article-title":"Improving survival in trisomy 18","volume":"188A","author":"Tamaki","year":"2022","journal-title":"Am J Med Genet Part A"},{"key":"10.1016\/j.jpeds.2022.05.043_bib15","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1002\/ajmg.a.62044","article-title":"A validated model for prediction of survival to 6 months in patients with trisomy 13 and 18","volume":"185A","author":"Kosiv","year":"2021","journal-title":"Am J Med Genet Part A"},{"key":"10.1016\/j.jpeds.2022.05.043_bib16","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1542\/peds.2012-0151","article-title":"The experience of families with children with trisomy 13 and 18 in social networks","volume":"130","author":"Janvier","year":"2012","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2022.05.043_bib17","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1002\/ajmg.c.31526","article-title":"Parental hopes, interventions, and survival of neonates with trisomy 13 and trisomy 18","volume":"172C","author":"Janvier","year":"2016","journal-title":"Am J Med Genet Part C Semin Med Genet"},{"key":"10.1016\/j.jpeds.2022.05.043_bib18","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1017\/S1047951120000013","article-title":"Mixed method study of quality of life for children with trisomy 18 and 13 after cardiac surgery","volume":"30","author":"Weaver","year":"2020","journal-title":"Cardiol Young"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347622005054?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347622005054?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T09:13:19Z","timestamp":1758359599000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347622005054"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":18,"alternative-id":["S0022347622005054"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2022.05.043","relation":{},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Survival Outcomes of Infants with the Trisomy 13 or Trisomy 18 Syndromes","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pediatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpeds.2022.05.043","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.jpeds.2022.03.057","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}