{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T12:42:17Z","timestamp":1780058537398,"version":"3.54.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","jpeds.com","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.jpeds.2023.113404","type":"journal-article","created":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T05:53:46Z","timestamp":1680587626000},"page":"113404","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Pulmonary Hypertension in Infants and Children with Vein of Galen Malformation and Association with Clinical Outcomes"],"prefix":"10.1016","volume":"258","author":[{"given":"Jai","family":"Khurana","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren B.","family":"Orbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberlee","family":"Gauvreau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shane L.","family":"Collins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph B.","family":"Tella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pankaj B.","family":"Agrawal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen A.","family":"Christou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0291-9630","authenticated-orcid":false,"given":"Mary P.","family":"Mullen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2023.113404_bib1","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.nec.2011.09.006","article-title":"Vein of Galen malformations: epidemiology, clinical presentations, management","volume":"23","author":"Recinos","year":"2012","journal-title":"Neurosurg Clin N Am"},{"key":"10.1016\/j.jpeds.2023.113404_bib2","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1111\/dmcn.14392","article-title":"Long-term outcome of vein of Galen malformation","volume":"62","author":"Taffin","year":"2020","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.jpeds.2023.113404_bib3","doi-asserted-by":"crossref","first-page":"B27","DOI":"10.1016\/j.ajog.2020.08.181","article-title":"Vein of Galen aneurysmal malformation","volume":"223","author":"Monteagudo","year":"2020","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.jpeds.2023.113404_bib4","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1136\/adc.78.6.548","article-title":"Congenital cardiac anomalies with vein of Galen malformations in infants","volume":"78","author":"McElhinney","year":"1998","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jpeds.2023.113404_bib5","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/BF00797009","article-title":"Sinus venosus atrial septal defect associated with vein of Galen malformations: report of two cases","volume":"15","author":"Friedman","year":"1995","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.jpeds.2023.113404_bib6","doi-asserted-by":"crossref","first-page":"630","DOI":"10.4103\/aer.AER_252_16","article-title":"Periprocedural management of vein of Galen aneurysmal malformation patients: an 11-Year experience","volume":"11","author":"Hrishi","year":"2017","journal-title":"Anesth Essays Res"},{"key":"10.1016\/j.jpeds.2023.113404_bib7","doi-asserted-by":"crossref","first-page":"e837","DOI":"10.1016\/j.wneu.2018.01.172","article-title":"Multimodality management of vein of Galen malformations-an Institutional experience","volume":"112","author":"Hosmann","year":"2018","journal-title":"World Neurosurg"},{"key":"10.1016\/j.jpeds.2023.113404_bib8","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1093\/neuros\/nyy100","article-title":"Vein of Galen aneurysmal malformation: advances in management and endovascular treatment","volume":"84","author":"Berenstein","year":"2019","journal-title":"Neurosurgery"},{"key":"10.1016\/j.jpeds.2023.113404_bib9","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1111\/dmcn.13676","article-title":"Presentation, course, and outcome of postneonatal presentations of vein of Galen malformation: a large, single-institution case series","volume":"60","author":"Gopalan","year":"2018","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.jpeds.2023.113404_bib10","doi-asserted-by":"crossref","first-page":"S184","DOI":"10.1227\/01.NEU.0000237445.39514.16","article-title":"The management of vein of Galen aneurysmal malformations","volume":"59","author":"Lasjaunias","year":"2006","journal-title":"Neurosurgery"},{"key":"10.1016\/j.jpeds.2023.113404_bib11","series-title":"Pediatric and congenital cardiac care","first-page":"163","article-title":"Early database initiatives: the Fyler codes","author":"Colan","year":"2015"},{"key":"10.1016\/j.jpeds.2023.113404_bib12","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1161\/01.CIR.68.1.68","article-title":"Interventricular septal configuration as a predictor of right ventricular systolic hypertension in children: a cross-sectional echocardiographic study","volume":"63","author":"King","year":"1983","journal-title":"Circulation"},{"key":"10.1016\/j.jpeds.2023.113404_bib13","doi-asserted-by":"crossref","first-page":"93","DOI":"10.7863\/jum.2005.24.1.93","article-title":"Perinatal Pseudcoarctation echocardiographic findings in vein of Galen malformation","volume":"24","author":"Doyle","year":"2005","journal-title":"J Ultrasound Med"},{"key":"10.1016\/j.jpeds.2023.113404_bib14","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jpeds.2019.10.090","article-title":"Management and outcomes of neonatal arteriovenous brain malformations with cardiac failure: a 17 Years' experience in a tertiary referral center","volume":"218","author":"Giorgi","year":"2020","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2023.113404_bib15","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.3174\/ajnr.A5403","article-title":"Endovascular treatment of vein of Galen malformations: a systematic review and meta-analysis","volume":"38","author":"Brinjikji","year":"2017","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.jpeds.2023.113404_bib16","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1136\/neurintsurg-2013-011005","article-title":"Radiological and clinical features of vein of Galen malformations","volume":"7","author":"Chow","year":"2015","journal-title":"J Neurointerv Surg"},{"key":"10.1016\/j.jpeds.2023.113404_bib17","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1007\/s00134-002-1381-8","article-title":"Severe cardiac failure in newborns with VGAM. Prognosis significance of hemodynamic parameters in neonates presenting with severe heart failure owing to vein of Galen arteriovenous malformation","volume":"28","author":"Chevret","year":"2002","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.jpeds.2023.113404_bib18","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1055\/s-0038-1666813","article-title":"Outcome of neonates with vein of Galen malformation presenting with severe heart failure: a case series","volume":"36","author":"De Rosa","year":"2019","journal-title":"Am J Perinatol"},{"key":"10.1016\/j.jpeds.2023.113404_bib19","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1093\/ons\/opy369","article-title":"Vein of Galen malformations: the Texas Children's Hospital experience in the modern endovascular Era","volume":"17","author":"Wagner","year":"2019","journal-title":"Oper Neurosurg (Hagerstown)"},{"key":"10.1016\/j.jpeds.2023.113404_bib20","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1002\/ana.25316","article-title":"Cross-sectional study of a United Kingdom cohort of neonatal vein of Galen malformation","volume":"84","author":"Lecce","year":"2018","journal-title":"Ann Neurol"},{"key":"10.1016\/j.jpeds.2023.113404_bib21","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1055\/s-2000-13456","article-title":"Persistent pulmonary hypertension of the newborn presenting as the primary manifestation of intracranial arteriovenous malformation of the vein of Galen","volume":"17","author":"Hendson","year":"2000","journal-title":"Am J Perinatology"},{"key":"10.1016\/j.jpeds.2023.113404_bib22","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1038\/sj.jp.7211752","article-title":"Systemic haemodynamics in infants with vein of Galen malformation: assessment and basis for therapy","volume":"27","author":"Patel","year":"2007","journal-title":"J. Perinatology"},{"key":"10.1016\/j.jpeds.2023.113404_bib23","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1007\/s00246-021-02627-9","article-title":"High output cardiovascular physiology and outcomes in Fetal diagnosis of vein of Galen malformation","volume":"42","author":"Jhaveri","year":"2021","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.jpeds.2023.113404_bib24","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1007\/s002460010294","article-title":"Severe pulmonary hypertensive vascular disease in two newborns with aneurysmal vein of Galen","volume":"22","author":"Dahdah","year":"2001","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.jpeds.2023.113404_bib25","doi-asserted-by":"crossref","first-page":"E205","DOI":"10.1093\/neuros\/nyz172","article-title":"Genetic drivers of vein of Galen malformations","volume":"85","author":"Starke","year":"2019","journal-title":"Neurosurgery"},{"key":"10.1016\/j.jpeds.2023.113404_bib26","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.neuron.2018.11.041","article-title":"Mutations in Chromatin modifier and Ephrin signaling genes in vein of Galen malformation","volume":"101","author":"Duran","year":"2019","journal-title":"Neuron"},{"key":"10.1016\/j.jpeds.2023.113404_bib27","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1093\/brain\/awy020","article-title":"Loss of function mutations in EPHB4 are responsible for vein of Galen aneurysmal malformation","volume":"141","author":"Vivanti","year":"2018","journal-title":"Brain"},{"key":"10.1016\/j.jpeds.2023.113404_bib28","first-page":"181","article-title":"ACVRL1 gene variant in a patient with vein of Galen aneurysmal malformation","volume":"2","author":"Chida","year":"2013","journal-title":"J Pediatr Genet"},{"key":"10.1016\/j.jpeds.2023.113404_bib29","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/s41390-022-02064-1","article-title":"Vein of Galen aneurysmal malformation: rationalizing medical management of neonatal heart failure","volume":"93","author":"Cory","year":"2023","journal-title":"Pediatr Res"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347623002317?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347623002317?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T01:22:04Z","timestamp":1739928124000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347623002317"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":29,"alternative-id":["S0022347623002317"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2023.113404","relation":{},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pulmonary Hypertension in Infants and Children with Vein of Galen Malformation and Association with Clinical Outcomes","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pediatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpeds.2023.113404","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"113404"}}