{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T21:38:49Z","timestamp":1793137129559,"version":"4.5.0"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100016275","name":"Seoul National University Bundang Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016275","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpeds.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.jpeds.2023.113515","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T20:55:11Z","timestamp":1685048111000},"page":"113515","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Characterization of Kikuchi-Fujimoto Disease in Children and Risk Factors Associated with Its Course"],"prefix":"10.1016","volume":"260","author":[{"given":"Sujin","family":"Choi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyoung Soo","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Jin","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Young","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Ho","family":"Paik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soyeon","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0107-0724","authenticated-orcid":false,"given":"Hyunju","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2023.113515_bib1","first-page":"379","article-title":"Lymphadenitis showing focal reticulin cell hyperplasia with nuclear debris and phagocytes: a clinicopathological study","volume":"35","author":"Kikuchi","year":"1972","journal-title":"Acta Haematol Jpn"},{"key":"10.1016\/j.jpeds.2023.113515_bib2","first-page":"920","article-title":"Cervical subacute necrotizing lymphadenitis","volume":"30","author":"Fujimoto","year":"1972","journal-title":"Naika"},{"key":"10.1016\/j.jpeds.2023.113515_bib3","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1002\/hon.2900080503","article-title":"Necrotizing lymphadenitis: a review of clinicopathological, immunohistochemical and ultrastructural studies","volume":"8","author":"Asano","year":"1990","journal-title":"Hematol Oncol"},{"key":"10.1016\/j.jpeds.2023.113515_bib4","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s004280050227","article-title":"Apoptosis of cytotoxic T-cells in histiocytic necrotizing lymphadenitis","volume":"433","author":"Ohshima","year":"1998","journal-title":"Virchows Arch"},{"key":"10.1016\/j.jpeds.2023.113515_bib5","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1046\/j.1365-2559.1998.00532.x","article-title":"Perforin and Fas pathways of cytotoxic T-cells in histiocytic necrotizing lymphadenitis","volume":"33","author":"Ohshima","year":"1998","journal-title":"Histopathology"},{"key":"10.1016\/j.jpeds.2023.113515_bib6","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1309\/1A6Y-YCKP-5AVF-QTYR","article-title":"Virus infection in patients with histiocytic necrotizing lymphadenitis in Taiwan. Detection of Epstein-Barr virus, type I human T-cell lymphotropic virus, and parvovirus B19","volume":"113","author":"Chiu","year":"2000","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.jpeds.2023.113515_bib7","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1093\/ajcp\/102.4.454","article-title":"Fine-needle aspiration cytologic diagnosis of Kikuchi's lymphadenitis. A report of 27 cases","volume":"102","author":"Tsang","year":"1994","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.jpeds.2023.113515_bib8","doi-asserted-by":"crossref","first-page":"E1519","DOI":"10.1002\/lary.29160","article-title":"Efficacy of ultrasound-Guided needle biopsy in the diagnosis of Kikuchi-Fujimoto disease","volume":"131","author":"Park","year":"2021","journal-title":"Laryngoscope"},{"key":"10.1016\/j.jpeds.2023.113515_bib9","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.jpeds.2015.12.064","article-title":"Clinical characteristics of severe histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto disease) in children","volume":"171","author":"Kang","year":"2016","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2023.113515_bib10","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.2147\/RMHP.S271283","article-title":"Risk Assessment of recurrence and autoimmune disorders in Kikuchi disease","volume":"13","author":"Jung","year":"2020","journal-title":"Risk Manag Healthc Policy"},{"key":"10.1016\/j.jpeds.2023.113515_bib11","doi-asserted-by":"crossref","first-page":"5505","DOI":"10.2147\/JIR.S378790","article-title":"Comparison of clinical characteristics and risk factors for recurrence of Kikuchi-Fujimoto disease between children and adult","volume":"15","author":"Baek","year":"2022","journal-title":"J Inflamm Res"},{"key":"10.1016\/j.jpeds.2023.113515_bib12","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1097\/MD.0000000000000220","article-title":"Kikuchi-Fujimoto disease: retrospective study of 91 cases and review of the literature","volume":"93","author":"Dumas","year":"2014","journal-title":"Medicine (Baltim)"},{"key":"10.1016\/j.jpeds.2023.113515_bib13","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1097\/INF.0000000000003397","article-title":"Kikuchi disease in children: case report and review of the literature","volume":"41","author":"Abdu","year":"2022","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jpeds.2023.113515_bib14","doi-asserted-by":"crossref","first-page":"745506","DOI":"10.3389\/fped.2021.745506","article-title":"Clinical and laboratory characteristics of Kikuchi-Fujimoto disease according to age","volume":"9","author":"Kim","year":"2021","journal-title":"Front Pediatr"},{"key":"10.1016\/j.jpeds.2023.113515_bib15","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1007\/s00431-014-2306-6","article-title":"Recurrent lymphadenopathy in children with Kikuchi-Fujimoto disease","volume":"173","author":"Yoo","year":"2014","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.jpeds.2023.113515_bib16","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1111\/jpc.14628","article-title":"Kikuchi-Fujimoto disease in children","volume":"56","author":"Selvanathan","year":"2020","journal-title":"J Paediatr Child Health"},{"key":"10.1016\/j.jpeds.2023.113515_bib17","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.2169\/internalmedicine.49.3919","article-title":"Treatment of histiocytic necrotizing lymphadenitis (Kikuchi's disease) with prolonged fever by a single course of methylprednisolone pulse therapy without maintenance therapy: experience with 13 cases","volume":"49","author":"Yoshioka","year":"2010","journal-title":"Intern Med"},{"key":"10.1016\/j.jpeds.2023.113515_bib18","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1258\/0022215001906561","article-title":"Management of Kikuchi's disease using glucocorticoid","volume":"114","author":"Jang","year":"2000","journal-title":"J Laryngol Otol"},{"key":"10.1016\/j.jpeds.2023.113515_bib19","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1007\/s00431-010-1256-x","article-title":"Kikuchi-Fujimoto disease: an amazing response to hydroxychloroquine","volume":"169","author":"Chen","year":"2010","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.jpeds.2023.113515_bib20","doi-asserted-by":"crossref","first-page":"3373","DOI":"10.2169\/internalmedicine.9205-17","article-title":"Recurrent Kikuchi-Fujimoto disease successfully treated by the concomitant use of hydroxychloroquine and corticosteroids","volume":"56","author":"Honda","year":"2017","journal-title":"Intern Med"},{"key":"10.1016\/j.jpeds.2023.113515_bib21","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.jmii.2017.08.023","article-title":"Pediatric Kikuchi-Fujimoto disease: a clinicopathologic study and the therapeutic effects of hydroxychloroquine","volume":"52","author":"Lin","year":"2019","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.jpeds.2023.113515_bib22","first-page":"998","article-title":"Childhood hemophagocytic syndrome associated with Kikuchi's disease","volume":"85","author":"Chen","year":"2000","journal-title":"Haematologica"},{"key":"10.1016\/j.jpeds.2023.113515_bib23","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1309\/YF081L4TKYWVYVPQ","article-title":"Enigmatic Kikuchi-Fujimoto disease: a comprehensive review","volume":"122","author":"Bosch","year":"2004","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.jpeds.2023.113515_bib24","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1177\/1066896912467369","article-title":"Recurrent histiocytic necrotizing lymphadenitis with a long latency in a patient with autoimmunity: a case report and review of literature","volume":"21","author":"Bogusz","year":"2013","journal-title":"Int J Surg Pathol"},{"key":"10.1016\/j.jpeds.2023.113515_bib25","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.ijid.2008.06.022","article-title":"Clinical outcome and predictive factors of recurrence among patients with Kikuchi's disease","volume":"13","author":"Song","year":"2009","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.jpeds.2023.113515_bib26","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1007\/s10067-008-0902-4","article-title":"Fatal Kikuchi-Fujimoto disease associated with SLE and hemophagocytic syndrome: a case report","volume":"27","author":"Kampitak","year":"2008","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.jpeds.2023.113515_bib27","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/S0194-59980223291-X","article-title":"Kikuchi's disease: a review and analysis of 61 cases","volume":"128","author":"Lin","year":"2003","journal-title":"Otolaryngol Head Neck Surg"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347623003633?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347623003633?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T09:15:26Z","timestamp":1758359726000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347623003633"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":27,"alternative-id":["S0022347623003633"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2023.113515","relation":{},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of Kikuchi-Fujimoto Disease in Children and Risk Factors Associated with Its Course","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pediatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpeds.2023.113515","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"113515"}}