{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T05:53:04Z","timestamp":1792216384070,"version":"4.4.0"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpeds.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.jpeds.2024.114017","type":"journal-article","created":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T22:22:23Z","timestamp":1710800543000},"page":"114017","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Predictors of Invasive Bacterial Infection in Febrile Infants Aged 2 to 6\u00a0Months in the Emergency Department"],"prefix":"10.1016","volume":"270","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9458-8276","authenticated-orcid":false,"given":"Rebecca S.","family":"Green","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura F.","family":"Sartori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd A.","family":"Florin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul L.","family":"Aronson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian E.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James M.","family":"Chamberlain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn M.","family":"Hunt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth A.","family":"Michelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lise E.","family":"Nigrovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2024.114017_bib1","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1097\/01.pec.0000236830.39194.c0","article-title":"Epidemiology of a pediatric emergency medicine research network: the PECARN Core Data Project","volume":"22","author":"Alpern","year":"2006","journal-title":"Pediatr Emerg Care"},{"key":"10.1016\/j.jpeds.2024.114017_bib2","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1001\/jamapediatrics.2016.0596","article-title":"Evaluation and management of febrile children: a review","volume":"170","author":"Cioffredi","year":"2016","journal-title":"JAMA Pediatr"},{"key":"10.1016\/j.jpeds.2024.114017_bib3","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1097\/PEC.0000000000001945","article-title":"Patient ethnicity and pediatric visits to the emergency department for fever","volume":"37","author":"Shapiro","year":"2021","journal-title":"Pediatr Emerg Care"},{"key":"10.1016\/j.jpeds.2024.114017_bib4","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.annemergmed.2022.06.014","article-title":"Prevalence and management of invasive bacterial infections in febrile infants ages 2 to 6 months","volume":"80","author":"Green","year":"2022","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.jpeds.2024.114017_bib5","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2015-4381","article-title":"European Group for Validation of the Step-by-Step Approach. Validation of the \u201cStep-by-Step\u201d approach in the management of young febrile infants","volume":"138","author":"Gomez","year":"2016","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2024.114017_bib6","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2018-3604","article-title":"A prediction model to identify febrile infants \u2264 60 Days at low risk of invasive bacterial infection","volume":"144","author":"Aronson","year":"2019","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2024.114017_bib7","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1001\/jamapediatrics.2018.5501","article-title":"A clinical prediction rule to identify febrile infants 60 Days and younger at low risk for serious bacterial infections","volume":"173","author":"Kuppermann","year":"2019","journal-title":"JAMA Pediatr"},{"key":"10.1016\/j.jpeds.2024.114017_bib8","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reports observational studies","volume":"370","author":"Elm","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.jpeds.2024.114017_bib9","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1186\/1471-2431-14-199","article-title":"Pediatric complex chronic conditions classification system version 2: updated for ICD-10 and complex medical technology dependence and transplantation","volume":"14","author":"Feudtner","year":"2014","journal-title":"BMC Pediatr"},{"key":"10.1016\/j.jpeds.2024.114017_bib10","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.annemergmed.2014.03.025","article-title":"Looking through the retrospectoscope: reducing bias in emergency medicine chart review studies","volume":"64","author":"Kaji","year":"2014","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.jpeds.2024.114017_bib11","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1093\/jpids\/piy125","article-title":"Reporting and categorization of blood culture contaminants in infants and young children: a scoping review","volume":"9","author":"Chappell-Campbell","year":"2020","journal-title":"J Pediatric Infect Dis Soc"},{"key":"10.1016\/j.jpeds.2024.114017_bib12","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.cmi.2018.03.030","article-title":"Contaminants in blood cultures: importance, implications, interpretation and prevention","volume":"24","author":"Darg\u00e8re","year":"2018","journal-title":"Clin Micro Infect"},{"key":"10.1016\/j.jpeds.2024.114017_bib13","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1001\/jama.297.1.52","article-title":"Clinical prediction rule for identifying children with cerebrospinal fluid pleocytosis at very low risk of bacterial meningitis","volume":"297","author":"Nigrovic","year":"2007","journal-title":"JAMA"},{"key":"10.1016\/j.jpeds.2024.114017_bib14","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1542\/hpeds.2018-0002","article-title":"Time to pathogen detection for non-ill versus ill-appearing infants \u226460 days old with bacteremia and meningitis","volume":"8","author":"Aronson","year":"2018","journal-title":"Hosp Pediatrics"},{"key":"10.1016\/j.jpeds.2024.114017_bib15","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1097\/01.inf.0000207485.39112.bf","article-title":"Changing epidemiology of outpatient bacteremia in 3- to 36-month-old children after the introduction of the heptavalent-conjugated pneumococcal vaccine","volume":"25","author":"Herz","year":"2006","journal-title":"Pediatric Infect Dis J"},{"key":"10.1016\/j.jpeds.2024.114017_bib16","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1097\/INF.0000000000000225","article-title":"The changing epidemiology of serious bacterial infections in young infants","volume":"33","author":"Greenhow","year":"2014","journal-title":"Pediatr Infect Dis J"},{"key":"10.1016\/j.jpeds.2024.114017_bib17","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2016-2098","article-title":"Bacteremia in children 3 to 36 months old after introduction of conjugated pneumococcal vaccines","volume":"139","author":"Greenhow","year":"2017","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2024.114017_bib18","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1136\/archdischild-2019-318548","article-title":"Height of fever and invasive bacterial infection","volume":"106","author":"Michelson","year":"2020","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jpeds.2024.114017_bib19","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S0196-0644(98)70225-2","article-title":"Predictors of occult pneumococcal bacteremia in young febrile children","volume":"31","author":"Kuppermann","year":"1998","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.jpeds.2024.114017_bib20","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/s00431-018-3098-x","article-title":"Hyperpyrexia and high fever as predictor for serious bacterial infection (SBI) in children-a systematic review","volume":"177","author":"Rosenfeld-Yehoshua","year":"2018","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.jpeds.2024.114017_bib21","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1542\/peds.104.1.79","article-title":"Oral versus initial intravenous therapy for urinary tract infections in young febrile children","volume":"104","author":"Hoberman","year":"1999","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2024.114017_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1542\/hpeds.2014-0051","article-title":"Diagnosis and management of bacteremic urinary tract infections in infants","volume":"5","author":"Roman","year":"2015","journal-title":"Hosp Pediatr"},{"key":"10.1016\/j.jpeds.2024.114017_bib23","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1097\/00006565-199510000-00004","article-title":"Bacteremia and meningitis among infants with urinary tract infections","volume":"11","author":"Bachur","year":"1995","journal-title":"Pediatr Emerg Care"},{"key":"10.1016\/j.jpeds.2024.114017_bib24","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2017-4087","article-title":"Timing and location of emergency department revisits","volume":"141","author":"Michelson","year":"2018","journal-title":"Pediatrics"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347624001203?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347624001203?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T22:28:52Z","timestamp":1762208932000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347624001203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":24,"alternative-id":["S0022347624001203"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2024.114017","relation":{},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Predictors of Invasive Bacterial Infection in Febrile Infants Aged 2 to 6\u00a0Months in the Emergency Department","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pediatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpeds.2024.114017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"114017"}}