{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T03:25:02Z","timestamp":1790220302953,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T00:00:00Z","timestamp":1715299200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004191","name":"Novo Nordisk A\/S","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","jpeds.com","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pediatrics"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.jpeds.2024.114089","type":"journal-article","created":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T07:07:52Z","timestamp":1715238472000},"page":"114089","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["The eTHINK Study: Cognitive and Behavioral Outcomes in Children with Hemophilia"],"prefix":"10.1016","volume":"272","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9775-5906","authenticated-orcid":false,"given":"Christine","family":"Mrakotsky","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin S.","family":"Walsh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathy","family":"Buranahirun Burns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacy E.","family":"Croteau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Markert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milan","family":"Geybels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cara","family":"Hannemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhvi","family":"Rajpurkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin A.","family":"Shapiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greta N.","family":"Wilkening","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela","family":"Ventola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David L.","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpeds.2024.114089_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/hae.14046","article-title":"WFH guidelines for the management of hemophilia, 3rd edition","volume":"26","author":"Srivastava","year":"2020","journal-title":"Haemophilia"},{"key":"10.1016\/j.jpeds.2024.114089_bib2","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1097\/00043426-199305000-00009","article-title":"Hemophilia growth and development study. Design, methods, and entry data","volume":"15","author":"Hilgartner","year":"1993","journal-title":"Am J Pediatr Hematol Oncol"},{"key":"10.1016\/j.jpeds.2024.114089_bib3","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/S0022-3476(98)70151-9","article-title":"Hemophilia morbidity, cognitive functioning, and academic achievement","volume":"133","author":"Usner","year":"1998","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpeds.2024.114089_bib4","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1093\/jpepsy\/19.2.223","article-title":"Hemophilia growth and development study: baseline neurodevelopmental findings","volume":"19","author":"Loveland","year":"1994","journal-title":"J Pediatr Psychol"},{"key":"10.1016\/j.jpeds.2024.114089_bib5","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1017\/S1355617700644028","article-title":"Attention in HIV-infected children: results from the hemophilia growth and development study","volume":"6","author":"Watkins","year":"2000","journal-title":"J Int Neuropsychol Soc"},{"key":"10.1016\/j.jpeds.2024.114089_bib6","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1046\/j.1365-2516.2003.00790.x","article-title":"Is attention deficit hyperactivity disorder over-represented among HIV-seronegative boys with haemophilia? Preliminary results from our centre","volume":"9","author":"Wodrich","year":"2003","journal-title":"Haemophilia"},{"key":"10.1016\/j.jpeds.2024.114089_bib7","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1111\/j.1365-2516.2009.01993.x","article-title":"Inattention, hyperactivity-impulsivity, academic skills and psychopathology in boys with and without haemophilia","volume":"15","author":"Spencer","year":"2009","journal-title":"Haemophilia"},{"key":"10.1016\/j.jpeds.2024.114089_bib8","doi-asserted-by":"crossref","first-page":"E105","DOI":"10.1542\/peds.108.6.e105","article-title":"Defining the impact of hemophilia: the academic achievement in children with hemophilia study","volume":"108","author":"Shapiro","year":"2001","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpeds.2024.114089_bib9","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1080\/00221325.1996.9914852","article-title":"The relationship of HIV status, type of coagulation disorder, and school absenteeism to cognition, educational performance, mood, and behavior of boys with hemophilia","volume":"157","author":"Mayes","year":"1996","journal-title":"J Genet Psychol"},{"key":"10.1016\/j.jpeds.2024.114089_bib10","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1586\/17474086.2014.947955","article-title":"Current management of hemophilia B: recommendations, complications and emerging issues","volume":"7","author":"Franchini","year":"2014","journal-title":"Expert Rev Hematol"},{"key":"10.1016\/j.jpeds.2024.114089_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12288-012-0209-0","article-title":"The history and evolution of the clinical effectiveness of haemophilia type A treatment: a systematic review","volume":"30","author":"Castro","year":"2014","journal-title":"Indian J Hematol Blood Transfus"},{"key":"10.1016\/j.jpeds.2024.114089_bib12","doi-asserted-by":"crossref","DOI":"10.1002\/pbc.28004","article-title":"Neuropsychological function in children with hemophilia: a review of the Hemophilia Growth and Development Study and introduction of the current eTHINK study","volume":"67","author":"Buranahirun","year":"2020","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.jpeds.2024.114089_bib13","series-title":"Bayley scales of infant and Toddler development - Third edition: Technical Manual","author":"Bayley","year":"2006"},{"key":"10.1016\/j.jpeds.2024.114089_bib14","series-title":"Wechsler preschool and Primary scale of intelligence","author":"Wechsler","year":"2012"},{"key":"10.1016\/j.jpeds.2024.114089_bib15","series-title":"Wechsler Abbreviated scale of intelligence","author":"Wechsler","year":"2011"},{"key":"10.1016\/j.jpeds.2024.114089_bib16","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s11060-015-1971-2","article-title":"CogState computerized memory tests in patients with brain metastases: secondary endpoint results of NRG Oncology RTOG 0933","volume":"126","author":"Caine","year":"2016","journal-title":"J Neuro Oncol"},{"key":"10.1016\/j.jpeds.2024.114089_bib17","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1089\/aid.2016.0026","article-title":"A randomized controlled trial to evaluate if computerized cognitive rehabilitation improves neurocognition in Ugandan children with HIV","volume":"32","author":"Boivin","year":"2016","journal-title":"AIDS Res Hum Retroviruses"},{"key":"10.1016\/j.jpeds.2024.114089_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0177177","article-title":"Cognitive function in multiple sclerosis improves with telerehabilitation: results from a randomized controlled trial","volume":"12","author":"Charvet","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.jpeds.2024.114089_bib19","doi-asserted-by":"crossref","first-page":"215","DOI":"10.4172\/2165-7386.1000215","article-title":"Neurocognitive changes after sustained ketamine administration in children with chronic pain","volume":"5","author":"Bredlau","year":"2015","journal-title":"J Palliat Care Med"},{"key":"10.1016\/j.jpeds.2024.114089_bib20","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1007\/s12603-009-0071-4","article-title":"Methodological improvements in quantifying cognitive change in clinical trials: an example with single-dose administration of donepezil","volume":"13","author":"Pietrzak","year":"2009","journal-title":"J Nutr Health Aging"},{"key":"10.1016\/j.jpeds.2024.114089_bib21","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1089\/cap.2016.0189","article-title":"Efficacy and safety of lurasidone in adolescents with schizophrenia: a 6-week, randomized placebo-controlled study","volume":"27","author":"Goldman","year":"2017","journal-title":"J Child Adolesc Psychopharmacol"},{"key":"10.1016\/j.jpeds.2024.114089_bib22","series-title":"Behavior rating Inventory of executive function - adult version (BRIEF-A) professional Manual","author":"Roth","year":"2005"},{"key":"10.1016\/j.jpeds.2024.114089_bib23","series-title":"Behavior rating Inventory of executive function - preschool version (BRIEF-P) professional Manual","author":"Gioia","year":"2003"},{"key":"10.1016\/j.jpeds.2024.114089_bib24","series-title":"Behavior rating Inventory of executive function","author":"Gioia","year":"2015"},{"key":"10.1016\/j.jpeds.2024.114089_bib25","series-title":"Behavioral assessment system for children","author":"Reynolds","year":"2015"},{"key":"10.1016\/j.jpeds.2024.114089_bib26","series-title":"Adaptive behavior assessment system - Third edition (ABAS-III)","author":"Harrison","year":"2015"},{"key":"10.1016\/j.jpeds.2024.114089_bib27","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J R Stat Soc Series B Stat Methodol"},{"key":"10.1016\/j.jpeds.2024.114089_bib29","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.intell.2016.11.006","article-title":"Socioeconomic status amplified the achievement gap throughout compulsory education independent of intelligence","volume":"60","author":"von Stumm","year":"2017","journal-title":"Intelligence"},{"key":"10.1016\/j.jpeds.2024.114089_bib30","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1177\/0963721421993116","article-title":"The role of parent educational attainment in parenting and children's development","volume":"30","author":"Davis-Kean","year":"2021","journal-title":"Curr Dir Psychol Sci"},{"key":"10.1016\/j.jpeds.2024.114089_bib31","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1177\/002246696900300103","article-title":"Intelligence, learning ability and socioeconomic status","volume":"3","author":"Jensen","year":"1969","journal-title":"J Spec Educ"},{"key":"10.1016\/j.jpeds.2024.114089_bib32","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.intell.2014.10.002","article-title":"Socioeconomic status and the growth of intelligence from infancy through adolescence","volume":"48","author":"von Stumm","year":"2015","journal-title":"Intelligence"},{"key":"10.1016\/j.jpeds.2024.114089_bib33","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1037\/0893-3200.19.2.294","article-title":"The influence of parent education and family income on child achievement: the indirect role of parental expectations and the home environment","volume":"19","author":"Davis-Kean","year":"2005","journal-title":"J Fam Psychol"},{"key":"10.1016\/j.jpeds.2024.114089_bib28","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1017\/S1355617713001434","article-title":"Cognitive functioning in young children with type 1 diabetes","volume":"20","author":"Cato","year":"2014","journal-title":"J Int Neuropsychol Soc"},{"key":"10.1016\/j.jpeds.2024.114089_bib34","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.2337\/dc07-2132","article-title":"Cognitive function in children with type 1 diabetes: a meta-analysis","volume":"31","author":"Gaudieri","year":"2008","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jpeds.2024.114089_bib35","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1002\/mrdd.20116","article-title":"Neurocognitive outcomes in children with chronic kidney disease: current findings and contemporary endeavors","volume":"12","author":"Gerson","year":"2006","journal-title":"Ment Retard Dev Disabil Res Rev"},{"key":"10.1016\/j.jpeds.2024.114089_bib36","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/pedi.12414","article-title":"A longitudinal investigation of cognitive function in children and adolescents with type 1 diabetes mellitus","volume":"18","author":"Kirchhoff","year":"2017","journal-title":"Pediatr Diabetes"},{"key":"10.1016\/j.jpeds.2024.114089_bib37","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1177\/0009922813495311","article-title":"Is executive function intact after pediatric intracranial hemorrhage? A sample of Mexican children with hemophilia","volume":"52","author":"Morales","year":"2013","journal-title":"Clin Pediatr (Phila)"},{"key":"10.1016\/j.jpeds.2024.114089_bib38","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1111\/j.1365-2516.2008.01815.x","article-title":"Long-term consequences of intracranial haemorrhage in children with haemophilia","volume":"15","author":"Bladen","year":"2009","journal-title":"Haemophilia"},{"key":"10.1016\/j.jpeds.2024.114089_bib39","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1111\/hae.12938","article-title":"The incidence, risk and functional outcomes of intracranial haemorrhage in children with inherited bleeding disorders at one haemophilia center","volume":"22","author":"Bladen","year":"2016","journal-title":"Haemophilia"}],"container-title":["The Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347624001926?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022347624001926?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T07:56:07Z","timestamp":1729238167000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022347624001926"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":39,"alternative-id":["S0022347624001926"],"URL":"https:\/\/doi.org\/10.1016\/j.jpeds.2024.114089","relation":{},"ISSN":["0022-3476"],"issn-type":[{"value":"0022-3476","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The eTHINK Study: Cognitive and Behavioral Outcomes in Children with Hemophilia","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pediatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpeds.2024.114089","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"114089"}}