{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T20:57:19Z","timestamp":1778187439480,"version":"3.51.4"},"reference-count":19,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pediatric Surgery"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1016\/j.jpedsurg.2011.09.026","type":"journal-article","created":{"date-parts":[[2011,12,11]],"date-time":"2011-12-11T00:37:26Z","timestamp":1323563846000},"page":"2358-2362","source":"Crossref","is-referenced-by-count":20,"title":["The effect of flutamide on expression of androgen and estrogen receptors in the gubernaculum and surrounding structures during testicular descent"],"prefix":"10.1016","volume":"46","author":[{"given":"Tamara R.","family":"Nation","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silverton","family":"Buraundi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Balic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela J.","family":"Farmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Don","family":"Newgreen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bridget R.","family":"Southwell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John M.","family":"Hutson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0005","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.1016\/j.jpedsurg.2009.07.072","article-title":"The antiandrogen, flutamide, perturbs inguinoscrotal testicular descent in the rat and suggests a link with mammary development","volume":"44","author":"Nation","year":"2009","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0010","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1016\/j.jpedsurg.2007.11.037","article-title":"Calcitonin gene-related peptide stimulates mitosis in the tip of the rat gubernaculum in vitro and provides the chemotactic signals to control gubernacular migration during testicular descent","volume":"43","author":"Yong","year":"2008","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0015","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.jpedsurg.2008.10.098","article-title":"Growth of the rat gubernaculum in vitro and localisation of its growth centre","volume":"44","author":"Ng","year":"2009","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0020","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1172\/JCI34241","article-title":"Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism","volume":"118","author":"Welsh","year":"2008","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0025","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/S0022-5347(17)36166-9","article-title":"Studies of the hormonal control of postnatal testicular descent in the rat","volume":"149","author":"Spencer","year":"1993","journal-title":"J Urol"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0030","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1210\/endo-128-1-383","article-title":"Localization of the androgen receptor in the developing rat gubernaculum","volume":"128","author":"Husmann","year":"1991","journal-title":"Endocrinology"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0035","unstructured":"Nation T, Buraundi S, Balic A, et al. Androgen and estrogen receptor expression in the spinal segments of the genitofemoral nerve during testicular descent. J Pediatr Surg; in press."},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0040","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.jpedsurg.2009.10.088","article-title":"Hidden in plain sight: the mammary line in males may be the missing link regulating inguinoscrotal testicular descent","volume":"45","author":"Balic","year":"2010","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0045","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.jpedsurg.2010.11.019","article-title":"The common fetal development of the mammary fat pad and gubernaculum","volume":"46","author":"Allnutt","year":"2011","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0050","doi-asserted-by":"crossref","first-page":"4716","DOI":"10.1210\/jc.2005-0211","article-title":"Association of cryptorchidism with a specific haplotype of the estrogen receptor alpha gene: implication for the susceptibility to estrogenic environmental endocrine disruptors","volume":"90","author":"Yoshida","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0055","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1093\/humupd\/dmm027","article-title":"Epidemiology and pathogenesis of cryptorchidism","volume":"14","author":"Virtanen","year":"2008","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0060","doi-asserted-by":"crossref","first-page":"4975","DOI":"10.1210\/jc.2005-1290","article-title":"Cryptorchidism\u2014an estrogen spoil?","volume":"90","author":"Agoulnik","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0065","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1095\/biolreprod.105.042796","article-title":"Expression of estrogen receptor ESR1 and its 46-kDa variant in the gubernaculum testis","volume":"73","author":"Staub","year":"2005","journal-title":"Biol Reprod"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0070","first-page":"325","article-title":"Effect of prenatal exposure to diethylstilbestrol on gubernacular development in fetal male mice","volume":"6","author":"Jiang","year":"2004","journal-title":"Asian J Androl"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0075","doi-asserted-by":"crossref","first-page":"5507","DOI":"10.1210\/en.2007-0689","article-title":"Estrogen receptor alpha is a major contributor to estrogen-mediated fetal testis dysgenesis and cryptorchidism","volume":"148","author":"Cederroth","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0080","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/S0022-3468(99)90774-1","article-title":"Localization of calcitonin gene-related peptide within the genitofemoral nerve in immature rats","volume":"34","author":"Schwindt","year":"1999","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0085","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/S0022-5347(17)32703-9","article-title":"Expression of androgen receptor protein within the lumbar spinal cord during ontologic development and following antiandrogen induced cryptorchidism","volume":"152","author":"Cain","year":"1994","journal-title":"J Urol"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0090","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/S0022-5347(01)65810-5","article-title":"Lack of feminization of the cremaster nucleus by prenatal flutamide administration in the rat and pig","volume":"156","author":"Barthold","year":"1996","journal-title":"J Urol"},{"key":"10.1016\/j.jpedsurg.2011.09.026_bb0095","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S0022-5347(17)35003-6","article-title":"Flutamide-induced testicular undescent in the rat is associated with alterations in genitofemoral nerve morphology","volume":"151","author":"Husmann","year":"1994","journal-title":"J Urol"}],"container-title":["Journal of Pediatric Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346811007652?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346811007652?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,20]],"date-time":"2019-06-20T14:55:37Z","timestamp":1561042537000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022346811007652"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12]]},"references-count":19,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["S0022346811007652"],"URL":"https:\/\/doi.org\/10.1016\/j.jpedsurg.2011.09.026","relation":{},"ISSN":["0022-3468"],"issn-type":[{"value":"0022-3468","type":"print"}],"subject":[],"published":{"date-parts":[[2011,12]]}}}