{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:59:28Z","timestamp":1786993168333,"version":"build-2736575974"},"reference-count":30,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","jpedsurg.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric Surgery"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.jpedsurg.2016.05.009","type":"journal-article","created":{"date-parts":[[2016,5,31]],"date-time":"2016-05-31T15:01:57Z","timestamp":1464706917000},"page":"1661-1664","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Common genetic variants of GPC1 gene reduce risk of biliary atresia in a Chinese population"],"prefix":"10.1016","volume":"51","author":[{"given":"Juntao","family":"Ke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuaidan","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxiong","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianyao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiao","family":"Lou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaoyuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueqin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu-Ming","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0005","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1097\/SLA.0b013e3182300950","article-title":"The anatomic pattern of biliary atresia identified at time of Kasai Hepatoportoenterostomy and early postoperative clearance of jaundice are significant predictors of transplant-free survival","volume":"254","author":"Superina","year":"2011","journal-title":"Ann Surg"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0010","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1016\/S0140-6736(09)60946-6","article-title":"Biliary atresia","volume":"374","author":"Hartley","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0015","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1097\/MCG.0b013e3181646730","article-title":"Biliary atresia: recent progress","volume":"42","author":"Bassett","year":"2008","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0020","first-page":"68","article-title":"Time\u2013space distribution of extrahepatic biliary atresia in the Netherlands and West Germany","volume":"43","author":"Houwen","year":"1988","journal-title":"Z Kinderchir"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0025","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/S0168-8278(99)80312-2","article-title":"Epidemiology of biliary atresia in France: a national study 1986-96","volume":"31","author":"Chardot","year":"1999","journal-title":"J Hepatol"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0030","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1542\/peds.99.3.376","article-title":"Epidemiology of biliary atresia: a population-based study","volume":"99","author":"Yoon","year":"1997","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0035","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0140-6736(99)03492-3","article-title":"The frequency and outcome of biliary atresia in the UK and Ireland","volume":"355","author":"McKiernan","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0040","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1002\/hep.22182","article-title":"Universal screening for biliary atresia using an infant stool color card in Taiwan","volume":"47","author":"Hsiao","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0045","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1055\/s-2007-985068","article-title":"The pathogenesis of biliary atresia: evidence for a virus-induced autoimmune disease","volume":"27","author":"Mack","year":"2007","journal-title":"Semin Liver Dis"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0050","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1751-0813.1990.tb07385.x","article-title":"Congenital biliary atresia and jaundice in lambs and calves","volume":"67","author":"Harper","year":"1990","journal-title":"Aust Vet J"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0055","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1097\/01.mpg.0000304465.60788.f4","article-title":"CFC1 gene involvement in biliary atresia with polysplenia syndrome","volume":"46","author":"Davit-Spraul","year":"2008","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0060","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1007\/s10620-007-9914-1","article-title":"Polymorphisms of the ICAM-1 gene are associated with biliary atresia","volume":"53","author":"Arikan","year":"2008","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0065","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1097\/01.mpg.0000192247.55583.fa","article-title":"Positive association of macrophage migration inhibitory factor gene-173G\/C polymorphism with biliary atresia","volume":"42","author":"Arikan","year":"2006","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0070","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1542\/peds.2004-1900","article-title":"Promoter polymorphism of the CD14 endotoxin receptor gene is associated with biliary atresia and idiopathic neonatal cholestasis","volume":"116","author":"Shih","year":"2005","journal-title":"Pediatrics"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0075","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1016\/j.jpedsurg.2008.03.037","article-title":"Upstream stimulatory factor 2 is implicated in the progression of biliary atresia by regulation of hepcidin expression","volume":"43","author":"Huang","year":"2008","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0080","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1002\/ajmg.a.33332","article-title":"Genomic alterations in biliary atresia suggest region of potential disease susceptibility in 2q37.3","volume":"152A","author":"Leyva-Vega","year":"2010","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0085","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1053\/j.gastro.2013.01.022","article-title":"Evidence from human and zebrafish that GPC1 is a biliary atresia susceptibility Gene","volume":"144","author":"Cui","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0090","doi-asserted-by":"crossref","first-page":"W600","DOI":"10.1093\/nar\/gkp290","article-title":"SNPinfo: integrating GWAS and candidate gene information into functional SNP selection for genetic association studies","volume":"37","author":"Xu","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0095","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1093\/hmg\/10.6.591","article-title":"Prediction of deleterious human alleles","volume":"10","author":"Sunyaev","year":"2001","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0100","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/bioinformatics\/bth457","article-title":"Haploview: analysis and visualization of LD and haplotype maps","volume":"21","author":"Barrett","year":"2005","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0105","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1086\/319501","article-title":"A new statistical method for haplotype reconstruction from population data","volume":"68","author":"Stephens","year":"2001","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0110","doi-asserted-by":"crossref","first-page":"D764","DOI":"10.1093\/nar\/gkt1168","article-title":"The UCSC genome browser database: 2014 update","volume":"42","author":"Karolchik","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0115","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/nature11247","article-title":"An integrated encyclopedia of DNA elements in the human genome","volume":"489","author":"Bernstein","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0120","doi-asserted-by":"crossref","first-page":"3421","DOI":"10.1007\/s00018-009-0096-1","article-title":"Multifunctionality of extracellular and cell surface heparan sulfate proteoglycans","volume":"66","author":"Kirn-Safran","year":"2009","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0125","doi-asserted-by":"crossref","first-page":"a002493","DOI":"10.1101\/cshperspect.a002493","article-title":"Shaping morphogen gradients by proteoglycans","volume":"1","author":"Yan","year":"2009","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0130","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1002\/hep.24156","article-title":"Hedgehog activity, epithelial-mesenchymal transitions, and biliary dysmorphogenesis in biliary atresia","volume":"53","author":"Omenetti","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0135","doi-asserted-by":"crossref","first-page":"D756","DOI":"10.1093\/nar\/gkt1114","article-title":"RefSeq: an update on mammalian reference sequences","volume":"42","author":"Pruitt","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0140","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1126\/science.1183621","article-title":"Variation in transcription factor binding among humans","volume":"328","author":"Kasowski","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0145","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1126\/science.1222794","article-title":"Systematic localization of common disease-associated variation in regulatory DNA","volume":"337","author":"Maurano","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.jpedsurg.2016.05.009_bb0150","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/nature11232","article-title":"The accessible chromatin landscape of the human genome","volume":"489","author":"Thurman","year":"2012","journal-title":"Nature"}],"container-title":["Journal of Pediatric Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346816300902?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346816300902?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,11]],"date-time":"2018-09-11T10:56:26Z","timestamp":1536663386000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022346816300902"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":30,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["S0022346816300902"],"URL":"https:\/\/doi.org\/10.1016\/j.jpedsurg.2016.05.009","relation":{},"ISSN":["0022-3468"],"issn-type":[{"value":"0022-3468","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Common genetic variants of GPC1 gene reduce risk of biliary atresia in a Chinese population","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpedsurg.2016.05.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}