{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T20:18:31Z","timestamp":1769113111280,"version":"3.49.0"},"reference-count":9,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","jpedsurg.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric Surgery"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.jpedsurg.2016.07.020","type":"journal-article","created":{"date-parts":[[2016,8,13]],"date-time":"2016-08-13T00:45:15Z","timestamp":1471049115000},"page":"1830-1833","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Altered expression of retinoblastoma 1 in Hirschsprung's disease"],"prefix":"10.1016","volume":"51","author":[{"given":"Anne Marie","family":"O'Donnell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Coyle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prem","family":"Puri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpedsurg.2016.07.020_bb0005","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1002\/jcp.24170","article-title":"Emerging roles of RB family: new defense mechanisms against tumor progression","volume":"228","author":"Indovina","year":"2013","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.jpedsurg.2016.07.020_bb0010","doi-asserted-by":"crossref","first-page":"5152","DOI":"10.1172\/JCI67653","article-title":"Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-obstruction","volume":"123","author":"Fu","year":"2013","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jpedsurg.2016.07.020_bb0015","doi-asserted-by":"crossref","first-page":"5201","DOI":"10.1038\/sj.onc.1209652","article-title":"Cell cycle control and beyond: emerging roles for the retinoblastoma gene family","volume":"25","author":"Genovese","year":"2006","journal-title":"Oncogene"},{"key":"10.1016\/j.jpedsurg.2016.07.020_bb0020","doi-asserted-by":"crossref","first-page":"928","DOI":"10.5858\/2002-126-0928-ADOICO","article-title":"Altered distribution of interstitial cells of Cajal in Hirschsprung disease","volume":"126","author":"Rolle","year":"2002","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.jpedsurg.2016.07.020_bb0025","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1111\/j.1365-2982.2011.01780.x","article-title":"The involvement of nitric oxide synthase neurons in enteric neuropathies","volume":"23","author":"Rivera","year":"2011","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.jpedsurg.2016.07.020_bb0030","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/(SICI)1096-8628(19980526)77:4<285::AID-AJMG7>3.0.CO;2-M","article-title":"Retinoblastoma and Hirschsprung disease in a patient with interstitial deletion of chromosome 13","volume":"77","author":"Weigel","year":"1998","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.jpedsurg.2016.07.020_bb0035","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1007\/BF00418397","article-title":"Separation of retinoblastoma and esterase D loci in a patient with sporadic retinoblastoma and del(13)(q14.1q22.3)","volume":"68","author":"Sparkes","year":"1984","journal-title":"Hum Genet"},{"key":"10.1016\/j.jpedsurg.2016.07.020_bb0040","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/BF01008017","article-title":"The distribution and co-localization of nitric oxide synthase and vasoactive intestinal polypeptide in nerves of the colons with Hirschsprung's disease","volume":"430","author":"Guo","year":"1997","journal-title":"Virchows Arch"},{"key":"10.1016\/j.jpedsurg.2016.07.020_bb0045","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1542\/peds.93.4.647","article-title":"Nitric oxide synthase is deficient in the aganglionic colon of patients with Hirschsprung's disease","volume":"93","author":"Bealer","year":"1994","journal-title":"Pediatrics"}],"container-title":["Journal of Pediatric Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002234681630224X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002234681630224X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T22:32:50Z","timestamp":1657060370000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002234681630224X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":9,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["S002234681630224X"],"URL":"https:\/\/doi.org\/10.1016\/j.jpedsurg.2016.07.020","relation":{},"ISSN":["0022-3468"],"issn-type":[{"value":"0022-3468","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Altered expression of retinoblastoma 1 in Hirschsprung's disease","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpedsurg.2016.07.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}