{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T21:51:16Z","timestamp":1790027476188,"version":"4.0.1"},"reference-count":19,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","jpedsurg.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric Surgery"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.jpedsurg.2016.10.021","type":"journal-article","created":{"date-parts":[[2016,10,27]],"date-time":"2016-10-27T05:03:11Z","timestamp":1477544591000},"page":"84-88","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Effectiveness of senna vs polyethylene glycol as laxative therapy in children with constipation related to anorectal malformation"],"prefix":"10.1016","volume":"52","author":[{"given":"Karla Alejandra","family":"Santos-Jasso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luis","family":"Arredondo-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Maza-Vallejos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Lezama-Del Valle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0005","first-page":"35","article-title":"Anorectal malformations","volume":"4","author":"Pe\u00f1a","year":"1995","journal-title":"Semin Pediatr Surg"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0010","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1016\/j.jpedsurg.2010.02.096","article-title":"The morbidity of constipation in patients with anorectal malformations","volume":"45","author":"Levitt","year":"2010","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0015","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1111\/j.1572-0241.2006.00771.x","article-title":"Epidemiology of childhood constipation: a systematic review","volume":"101","author":"Van den Berg","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0020","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1056\/NEJMra020995","article-title":"Chronic constipation","volume":"349","author":"Lembo","year":"2003","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1016\/j.jpedsurg.2016.10.021_bb0025","first-page":"111","article-title":"Efectividad del programa de rehabilitaci\u00f3n intestinal en ni\u00f1os con estre\u00f1imiento secundario a malformaci\u00f3n anorrectal","volume":"35","author":"Santos-Jasso","year":"2014","journal-title":"Acta Pediatr Mex"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0030","series-title":"Manual de Prescripci\u00f3n Pedi\u00e1trica","author":"Taketomo","year":"2010"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0035","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0022-3468(98)90380-3","article-title":"Bowel management for fecal incontinence in patients with anorectal malformations","volume":"33","author":"Pe\u00f1a","year":"1998","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0040","first-page":"155","article-title":"Gu\u00edas de diagn\u00f3stico y tratamiento del estre\u00f1imiento en M\u00e9xico. D Evaluaci\u00f3n y tratamiento del estre\u00f1imiento en poblaci\u00f3n pedi\u00e1trica","volume":"76","author":"Remes","year":"2011","journal-title":"Rev Gastroenterol Mex"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0045","series-title":"En Goodman y Gilman. Las Bases Farmacol\u00f3gicas de la Terap\u00e9utica","first-page":"981","article-title":"F\u00e1rmacos que afectan el flujo de agua y la motilidad gastrointestinales: emesis y antiem\u00e9ticos; \u00e1cidos biliares y enzimas pancre\u00e1ticas","author":"Brunton","year":"2006"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0050","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1136\/adc.2007.127233","article-title":"Currently recommended treatments of childhood constipation are not evidenced based: a systematic literature review on the effect of laxative treatment and dietary measures","volume":"94","author":"Pijpers","year":"2009","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0055","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.gtc.2010.08.001","article-title":"Pharmacologic management of chronic constipation","volume":"39","author":"Singh","year":"2010","journal-title":"Gastroenterol Clin N Am"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0060","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1177\/000992280204100405","article-title":"Comparison of polyethylene glycol 3350 and lactulose for treatment of chronic constipation in children","volume":"41","author":"Gremse","year":"2002","journal-title":"Clin Pediatr"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0065","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1055\/s-2005-870894","article-title":"Childhood constipation: evaluation and management","volume":"18","author":"Pashankar","year":"2005","journal-title":"Clin Colon Rectal Surg"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0070","first-page":"CD009118","article-title":"Osmotic and stimulant laxatives for the management of childhood constipation","volume":"7","author":"Gordon","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0075","series-title":"En: la Biblioteca Cochrane plus","article-title":"Laxantes estimulantes para el estre\u00f1imiento y la encopresis en ni\u00f1os (revisi\u00f3n Cochrane traducida)","volume":"N\u00famero 4","author":"Price","year":"2008"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0080","series-title":"En: anorectal Malformations in Children","first-page":"222","article-title":"Postoperative pathophysiology of chronic constipation and stool incontinence","author":"Holschneider","year":"2006"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0085","article-title":"Is Senna laxative use associated to cathartic colon, genotoxicity, or carcinogenicity?","volume":"287247","author":"Morales","year":"2009","journal-title":"J Toxicol"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0090","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/0306-4522(89)90175-9","article-title":"Sennosides do not kill myenteric neurons in the colon of the rat or mouse","volume":"30","author":"Kiernan","year":"1989","journal-title":"Neuroscience"},{"key":"10.1016\/j.jpedsurg.2016.10.021_bb0095","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s00204-005-0021-9","article-title":"An oral carcinogenicity and toxicity study of Senna (Tinnevelly senna fruits) in the rat","volume":"80","author":"JM","year":"2006","journal-title":"Arch Toxicol"}],"container-title":["Journal of Pediatric Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346816304821?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346816304821?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,7]],"date-time":"2018-09-07T02:57:51Z","timestamp":1536289071000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022346816304821"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["S0022346816304821"],"URL":"https:\/\/doi.org\/10.1016\/j.jpedsurg.2016.10.021","relation":{},"ISSN":["0022-3468"],"issn-type":[{"value":"0022-3468","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effectiveness of senna vs polyethylene glycol as laxative therapy in children with constipation related to anorectal malformation","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpedsurg.2016.10.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}