{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T13:15:46Z","timestamp":1780578946253,"version":"3.54.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","jpedsurg.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric Surgery"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1016\/j.jpedsurg.2017.03.017","type":"journal-article","created":{"date-parts":[[2017,3,16]],"date-time":"2017-03-16T20:15:39Z","timestamp":1489695339000},"page":"956-961","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"title":["Vascular invasion is a prognostic indicator in hepatoblastoma"],"prefix":"10.1016","volume":"52","author":[{"given":"Yan","family":"Shi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah J.","family":"Commander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakash M.","family":"Masand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andras","family":"Heczey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Goss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeev A.","family":"Vasudevan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jpedsurg.2017.03.017_bb0005","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1111\/j.1365-3016.1990.tb00651.x","article-title":"Malignant hepatic tumours in children: incidence, clinical features and aetiology","volume":"4","author":"Mann","year":"1990","journal-title":"Paediatr Perinat Epidemiol"},{"issue":"10","key":"10.1016\/j.jpedsurg.2017.03.017_bb0010","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1016\/j.ejca.2011.12.011","article-title":"Prognostic stratification for children with hepatoblastoma: the SIOPEL experience","volume":"48","author":"Maibach","year":"2012","journal-title":"Eur J Cancer"},{"issue":"1","key":"10.1016\/j.jpedsurg.2017.03.017_bb0015","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/MOP.0000000000000046","article-title":"Hepatoblastoma state of the art: pathology, genetics, risk stratification, and chemotherapy","volume":"26","author":"Czauderna","year":"2014","journal-title":"Curr Opin Pediatr"},{"issue":"24","key":"10.1016\/j.jpedsurg.2017.03.017_bb0020","doi-asserted-by":"crossref","first-page":"3301","DOI":"10.1200\/JCO.2010.29.3837","article-title":"Complete surgical resection is curative for children with hepatoblastoma with pure fetal histology: a report from the Children's Oncology Group","volume":"29","author":"Malogolowkin","year":"2011","journal-title":"J Clin Oncol"},{"issue":"1","key":"10.1016\/j.jpedsurg.2017.03.017_bb0025","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0748-7983(05)80083-6","article-title":"Paediatric surgical oncology. 2\u2014primary liver tumours in children","volume":"21","author":"Vos","year":"1995","journal-title":"Eur J Surg Oncol"},{"issue":"6","key":"10.1016\/j.jpedsurg.2017.03.017_bb0030","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1002\/pbc.22088","article-title":"Predictive power of pretreatment prognostic factors in children with hepatoblastoma: a report from the Children's Oncology Group","volume":"53","author":"Meyers","year":"2009","journal-title":"Pediatr Blood Cancer"},{"issue":"6","key":"10.1016\/j.jpedsurg.2017.03.017_bb0035","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1200\/JCO.2005.07.145","article-title":"Predictive value of the pretreatment extent of disease system in hepatoblastoma: results from the International Society of Pediatric Oncology Liver Tumor Study Group SIOPEL-1 study","volume":"23","author":"Aronson","year":"2005","journal-title":"J Clin Oncol Off J Am Soc Clin Oncol"},{"issue":"11","key":"10.1016\/j.jpedsurg.2017.03.017_bb0040","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1016\/S0959-8049(00)00074-5","article-title":"Pretreatment prognostic factors for children with hepatoblastoma\u2014results from the International Society of Paediatric Oncology (SIOP) study SIOPEL 1","volume":"36","author":"Brown","year":"2000","journal-title":"Eur J Cancer"},{"issue":"22","key":"10.1016\/j.jpedsurg.2017.03.017_bb0045","doi-asserted-by":"crossref","first-page":"3819","DOI":"10.1200\/JCO.2000.18.22.3819","article-title":"Cisplatin, doxorubicin, and delayed surgery for childhood hepatoblastoma: a successful approach\u2014results of the first prospective study of the International Society of Pediatric Oncology","volume":"18","author":"Pritchard","year":"2000","journal-title":"J Clin Oncol"},{"issue":"15","key":"10.1016\/j.jpedsurg.2017.03.017_bb0050","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.1200\/JCO.2009.22.4857","article-title":"Successful treatment of childhood high-risk hepatoblastoma with dose-intensive multiagent chemotherapy and surgery: final results of the SIOPEL-3HR study","volume":"28","author":"Zsiros","year":"2010","journal-title":"J Clin Oncol"},{"issue":"6","key":"10.1016\/j.jpedsurg.2017.03.017_bb0055","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1002\/(SICI)1097-0215(19971219)74:6<593::AID-IJC6>3.0.CO;2-P","article-title":"Prognostic factors and staging systems in childhood hepatoblastoma","volume":"74","author":"von Schweinitz","year":"1997","journal-title":"Int J Cancer"},{"issue":"11","key":"10.1016\/j.jpedsurg.2017.03.017_bb0060","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1016\/j.ejso.2014.07.033","article-title":"Predictors of survival after resection of children with hepatoblastoma: a single Asian center experience","volume":"40","author":"Qiao","year":"2014","journal-title":"Eur J Surg Oncol"},{"issue":"6","key":"10.1016\/j.jpedsurg.2017.03.017_bb0065","doi-asserted-by":"crossref","first-page":"387","DOI":"10.6061\/clinics\/2015(06)01","article-title":"New concepts and outcomes for children with hepatoblastoma based on the experience of a tertiary center over the last 21 years","volume":"70","author":"Tannuri","year":"2015","journal-title":"Clinics"},{"key":"10.1016\/j.jpedsurg.2017.03.017_bb0070","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.ejca.2015.09.023","article-title":"The Children's Hepatic Tumors International Collaboration (CHIC): novel global rare tumor database yields new prognostic factors in hepatoblastoma and becomes a research model","volume":"52","author":"Czauderna","year":"2016","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.jpedsurg.2017.03.017_bb0075","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1002\/cncr.10632","article-title":"Pretreatment prognostic factors and treatment results in children with hepatoblastoma: a report from the German Cooperative Pediatric Liver Tumor Study HB 94","volume":"95","author":"Fuchs","year":"2002","journal-title":"Cancer"},{"issue":"2","key":"10.1016\/j.jpedsurg.2017.03.017_bb0080","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.jss.2015.03.087","article-title":"Intraoperative ultrasound for liver tumor resection in children","volume":"198","author":"Felsted","year":"2015","journal-title":"J Surg Res"},{"issue":"1","key":"10.1016\/j.jpedsurg.2017.03.017_bb0085","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/MOP.0000000000000042","article-title":"Hepatoblastoma state of the art: pre-treatment extent of disease, surgical resection guidelines and the role of liver transplantation","volume":"26","author":"Meyers","year":"2014","journal-title":"Curr Opin Pediatr"},{"issue":"5","key":"10.1016\/j.jpedsurg.2017.03.017_bb0090","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1002\/pbc.24219","article-title":"Chemotherapeutic approaches for newly diagnosed hepatoblastoma: past, present, and future strategies","volume":"59","author":"Trobaugh-Lotrario","year":"2012","journal-title":"Pediatr Blood Cancer"},{"issue":"6","key":"10.1016\/j.jpedsurg.2017.03.017_bb0095","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1007\/s10147-013-0616-8","article-title":"Current chemotherapeutic approaches for hepatoblastoma","volume":"18","author":"Watanabe","year":"2013","journal-title":"Int J Clin Oncol"},{"issue":"9","key":"10.1016\/j.jpedsurg.2017.03.017_bb0100","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/S1470-2045(13)70272-9","article-title":"Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study","volume":"14","author":"Zsiros","year":"2013","journal-title":"Lancet Oncol"},{"issue":"5","key":"10.1016\/j.jpedsurg.2017.03.017_bb0105","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1111\/j.1399-3046.2005.00354.x","article-title":"Liver transplantation for hepatoblastoma: indications and contraindications in the modern era","volume":"9","author":"Otte","year":"2005","journal-title":"Pediatr Transplant"},{"issue":"8","key":"10.1016\/j.jpedsurg.2017.03.017_bb0110","doi-asserted-by":"crossref","first-page":"812","DOI":"10.4161\/cc.5.8.2646","article-title":"Lymphatic or hematogenous dissemination: how does a metastatic tumor cell decide?","volume":"5","author":"Wong","year":"2006","journal-title":"Cell Cycle"},{"issue":"4","key":"10.1016\/j.jpedsurg.2017.03.017_bb0115","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.ejca.2012.10.003","article-title":"Relapses in hepatoblastoma patients: clinical characteristics and outcome\u2014experience of the International Childhood Liver Tumour Strategy Group (SIOPEL)","volume":"49","author":"Semeraro","year":"2013","journal-title":"Eur J Cancer"},{"issue":"5","key":"10.1016\/j.jpedsurg.2017.03.017_bb0120","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1002\/pbc.24220","article-title":"Surgical treatment of hepatoblastoma","volume":"59","author":"Meyers","year":"2012","journal-title":"Pediatr Blood Cancer"},{"issue":"4","key":"10.1016\/j.jpedsurg.2017.03.017_bb0125","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1053\/j.sempedsurg.2005.06.006","article-title":"The contribution of transplantation to the treatment of liver tumors in children","volume":"14","author":"Otte","year":"2005","journal-title":"Semin Pediatr Surg"},{"issue":"4","key":"10.1016\/j.jpedsurg.2017.03.017_bb0130","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.ctrv.2010.02.013","article-title":"Progress in the surgical treatment of malignant liver tumors in children","volume":"36","author":"Otte","year":"2010","journal-title":"Cancer Treat Rev"},{"issue":"7","key":"10.1016\/j.jpedsurg.2017.03.017_bb0135","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1111\/j.1399-3046.2010.01395.x","article-title":"PLUTO first report","volume":"14","author":"Otte","year":"2010","journal-title":"Pediatr Transplant"},{"issue":"1","key":"10.1016\/j.jpedsurg.2017.03.017_bb0140","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/pbc.10376","article-title":"Liver transplantation for hepatoblastoma: results from the International Society of Pediatric Oncology (SIOP) study SIOPEL-1 and review of the world experience","volume":"42","author":"Otte","year":"2004","journal-title":"Pediatr Blood Cancer"},{"issue":"5","key":"10.1016\/j.jpedsurg.2017.03.017_bb0145","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1053\/jhep.2001.23561","article-title":"Vascular invasion and histopathologic grading determine outcome after liver transplantation for hepatocellular carcinoma in cirrhosis","volume":"33","author":"Jonas","year":"2001","journal-title":"Hepatology"},{"issue":"5","key":"10.1016\/j.jpedsurg.2017.03.017_bb0150","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1245\/s10434-008-9846-9","article-title":"Microvascular invasion in patients with hepatocellular carcinoma and its predictable clinicopathological factors","volume":"15","author":"Sumie","year":"2008","journal-title":"Ann Surg Oncol"},{"issue":"6","key":"10.1016\/j.jpedsurg.2017.03.017_bb0155","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1002\/lt.24441","article-title":"An early look at the Organ Procurement and Transplantation Network explant pathology form data","volume":"22","author":"Harper","year":"2016","journal-title":"Liver Transpl"}],"container-title":["Journal of Pediatric Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346817301665?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346817301665?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,3]],"date-time":"2018-09-03T08:55:59Z","timestamp":1535964959000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022346817301665"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":31,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["S0022346817301665"],"URL":"https:\/\/doi.org\/10.1016\/j.jpedsurg.2017.03.017","relation":{},"ISSN":["0022-3468"],"issn-type":[{"value":"0022-3468","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vascular invasion is a prognostic indicator in hepatoblastoma","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpedsurg.2017.03.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}