{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T11:48:26Z","timestamp":1776426506310,"version":"3.51.2"},"reference-count":40,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,5,28]],"date-time":"2020-05-28T00:00:00Z","timestamp":1590624000000},"content-version":"am","delay-in-days":362,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpedsurg.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric Surgery"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.jpedsurg.2019.02.026","type":"journal-article","created":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T02:14:51Z","timestamp":1551320091000},"page":"1239-1244","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Lymphatic network remodeling after small bowel resection"],"prefix":"10.1016","volume":"54","author":[{"given":"Emily J.","family":"Onufer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Czepielewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristen M.","family":"Seiler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emma","family":"Erlich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cathleen M.","family":"Courtney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aiza","family":"Bustos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gwendalyn J.","family":"Randolph","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brad W","family":"Warner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jpedsurg.2019.02.026_bb0005","first-page":"1230","article-title":"Extreme short bowel syndrome in neonates: an indication for small bowel transplantation?","volume":"24","author":"Wallander","year":"1992","journal-title":"Transplant Proc"},{"issue":"4","key":"10.1016\/j.jpedsurg.2019.02.026_bb0010","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1007\/s10620-006-9416-6","article-title":"Short bowel syndrome: parenteral nutrition versus intestinal transplantation. Where are we today?","volume":"52","author":"DeLegge","year":"2007","journal-title":"Dig Dis Sci"},{"issue":"4","key":"10.1016\/j.jpedsurg.2019.02.026_bb0015","doi-asserted-by":"crossref","first-page":"723-8.e2","DOI":"10.1016\/j.jpeds.2012.03.062","article-title":"Natural history of pediatric intestinal failure: initial report from the Pediatric Intestinal Failure Consortium","volume":"161","author":"Squires","year":"2012","journal-title":"J Pediatr"},{"issue":"3","key":"10.1016\/j.jpedsurg.2019.02.026_bb0020","doi-asserted-by":"crossref","first-page":"e573","DOI":"10.1542\/peds.2007-3449","article-title":"Very low birth weight preterm infants with surgical short bowel syndrome: incidence, morbidity and mortality, and growth outcomes at 18 to 22 months","volume":"122","author":"Cole","year":"2008","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.jpedsurg.2019.02.026_bb0025","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.jpedsurg.2011.11.032","article-title":"Intestinal failure-associated liver disease in surgical infants requiring long-term parenteral nutrition","volume":"47","author":"Bishay","year":"2012","journal-title":"J Pediatr Surg"},{"issue":"2","key":"10.1016\/j.jpedsurg.2019.02.026_bb0030","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1177\/0148607115584388","article-title":"Intestinal microbiota signatures associated with histological liver steatosis in pediatric-onset intestinal failure","volume":"41","author":"Korpela","year":"2017","journal-title":"JPEN J Parenter Enteral Nutr"},{"issue":"4","key":"10.1016\/j.jpedsurg.2019.02.026_bb0035","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/S0022-3468(96)90507-2","article-title":"Parenteral nutrition-related cholestasis in postsurgical neonates: multivariate analysis of risk factors","volume":"31","author":"Beath","year":"1996","journal-title":"J Pediatr Surg"},{"issue":"3","key":"10.1016\/j.jpedsurg.2019.02.026_bb0040","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1097\/MOP.0000000000000484","article-title":"Pediatric intestinal failure-associated liver disease","volume":"29","author":"Courtney","year":"2017","journal-title":"Curr Opin Pediatr"},{"issue":"2","key":"10.1016\/j.jpedsurg.2019.02.026_bb0045","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1136\/flgastro-2015-100560","article-title":"Reversal of intestinal failure-associated liver disease (IFALD): emphasis on its multifactorial nature","volume":"7","author":"Hvas","year":"2016","journal-title":"Frontline gastroenterol"},{"key":"10.1016\/j.jpedsurg.2019.02.026_bb0050","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1038\/nrgastro.2017.79","article-title":"Intestinal lymphatic vasculature: structure, mechanisms and functions","volume":"14","author":"Bernier-Latmani","year":"2017","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.jpedsurg.2019.02.026_bb0055","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1146\/annurev-immunol-041015-055354","article-title":"The lymphatic system: integral roles in immunity","volume":"35","author":"Randolph","year":"2017","journal-title":"Annu Rev Immunol"},{"issue":"6402","key":"10.1016\/j.jpedsurg.2019.02.026_bb0060","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1126\/science.aap9331","article-title":"Lacteal junction zippering protects against diet-induced obesity","volume":"361","author":"Zhang","year":"2018","journal-title":"Science"},{"issue":"Suppl. 1","key":"10.1016\/j.jpedsurg.2019.02.026_bb0065","first-page":"E21","article-title":"Microanatomy of the intestinal lymphatic system","volume":"1207","author":"Miller","year":"2010","journal-title":"Ann N Y Acad Sci"},{"issue":"1","key":"10.1016\/j.jpedsurg.2019.02.026_bb0070","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/DCR.0b013e3181fb0e7a","article-title":"Lymphatic vessel distribution in the mucosa and submucosa and potential implications for T1 colorectal tumors","volume":"54","author":"Smith","year":"2011","journal-title":"Dis Colon Rectum"},{"issue":"4","key":"10.1016\/j.jpedsurg.2019.02.026_bb0075","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1083\/jcb.201012094","article-title":"Lymphatic vascular morphogenesis in development, physiology, and disease","volume":"193","author":"Schulte-Merker","year":"2011","journal-title":"J Cell Biol"},{"issue":"20","key":"10.1016\/j.jpedsurg.2019.02.026_bb0080","doi-asserted-by":"crossref","first-page":"5749","DOI":"10.1113\/JP272088","article-title":"Lymphatic pumping: mechanics, mechanisms and malfunction","volume":"594","author":"Scallan","year":"2016","journal-title":"J Physiol"},{"issue":"12","key":"10.1016\/j.jpedsurg.2019.02.026_bb0085","doi-asserted-by":"crossref","first-page":"4572","DOI":"10.1172\/JCI82045","article-title":"DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport","volume":"125","author":"Bernier-Latmani","year":"2015","journal-title":"J Clin Invest"},{"issue":"1","key":"10.1016\/j.jpedsurg.2019.02.026_bb0090","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1679\/aohc.71.1","article-title":"Organization and developmental aspects of lymphatic vessels","volume":"71","author":"Ohtani","year":"2008","journal-title":"Arch Histol Cytol"},{"issue":"11","key":"10.1016\/j.jpedsurg.2019.02.026_bb0095","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.15252\/emmm.201505731","article-title":"VEGF-C is required for intestinal lymphatic vessel maintenance and lipid absorption","volume":"7","author":"Nurmi","year":"2015","journal-title":"EMBO Mol Med"},{"issue":"6","key":"10.1016\/j.jpedsurg.2019.02.026_bb0100","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/S0092-8674(00)81511-1","article-title":"Prox1 function is required for the development of the murine lymphatic system","volume":"98","author":"Wigle","year":"1999","journal-title":"Cell"},{"issue":"7","key":"10.1016\/j.jpedsurg.2019.02.026_bb0105","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1093\/emboj\/21.7.1505","article-title":"An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype","volume":"21","author":"Wigle","year":"2002","journal-title":"EMBO J"},{"issue":"22","key":"10.1016\/j.jpedsurg.2019.02.026_bb0110","doi-asserted-by":"crossref","first-page":"19420","DOI":"10.1074\/jbc.M011004200","article-title":"Mouse LYVE-1 is an endocytic receptor for hyaluronan in lymphatic endothelium","volume":"276","author":"Prevo","year":"2001","journal-title":"J Biol Chem"},{"issue":"13","key":"10.1016\/j.jpedsurg.2019.02.026_bb0115","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1182\/blood-2013-01-478941","article-title":"Conditional ablation of LYVE-1+ cells unveils defensive roles of lymphatic vessels in intestine and lymph nodes","volume":"122","author":"Jang","year":"2013","journal-title":"Blood"},{"issue":"12","key":"10.1016\/j.jpedsurg.2019.02.026_bb0120","doi-asserted-by":"crossref","first-page":"3066","DOI":"10.1016\/j.ajpath.2016.07.026","article-title":"Lymphoid aggregates remodel lymphatic collecting vessels that serve mesenteric lymph nodes in Crohn Disease","volume":"186","author":"Randolph","year":"2016","journal-title":"Am J Pathol"},{"issue":"2","key":"10.1016\/j.jpedsurg.2019.02.026_bb0125","doi-asserted-by":"crossref","first-page":"19","DOI":"10.4251\/wjgo.v3.i2.19","article-title":"Intestinal lymphangiectasia in adults","volume":"3","author":"Freeman","year":"2011","journal-title":"World J Gastrointest Oncol"},{"issue":"1","key":"10.1016\/j.jpedsurg.2019.02.026_bb0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/gut.2007.123166","article-title":"The forgotten role of lymphangitis in Crohn's disease","volume":"57","author":"Van Kruiningen","year":"2008","journal-title":"Gut"},{"issue":"6","key":"10.1016\/j.jpedsurg.2019.02.026_bb0135","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1111\/j.1365-2036.2010.04407.x","article-title":"Review article: lymphatic system and associated adipose tissue in the development of inflammatory bowel disease","volume":"32","author":"von der Weid","year":"2010","journal-title":"Aliment Pharmacol Ther"},{"issue":"19","key":"10.1016\/j.jpedsurg.2019.02.026_bb0140","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.1101\/gad.1588407","article-title":"Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature","volume":"21","author":"Srinivasan","year":"2007","journal-title":"Genes Dev"},{"issue":"5","key":"10.1016\/j.jpedsurg.2019.02.026_bb0145","first-page":"441","article-title":"Intestinal adaptation following massive small bowel resection in the mouse","volume":"183","author":"Helmrath","year":"1996","journal-title":"J Am Coll Surg"},{"issue":"18","key":"10.1016\/j.jpedsurg.2019.02.026_bb0150","doi-asserted-by":"crossref","first-page":"3358","DOI":"10.1242\/jcs.050005","article-title":"Sumoylation of Prox1 controls its ability to induce VEGFR3 expression and lymphatic phenotypes in endothelial cells","volume":"122","author":"Pan","year":"2009","journal-title":"J Cell Sci"},{"issue":"17","key":"10.1016\/j.jpedsurg.2019.02.026_bb0155","doi-asserted-by":"crossref","first-page":"4593","DOI":"10.1093\/emboj\/cdf470","article-title":"Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor","volume":"21","author":"Petrova","year":"2002","journal-title":"EMBO J"},{"issue":"8","key":"10.1016\/j.jpedsurg.2019.02.026_bb0160","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.1172\/JCI79386","article-title":"Lymph flow regulates collecting lymphatic vessel maturation in vivo","volume":"125","author":"Sweet","year":"2015","journal-title":"J Clin Invest"},{"issue":"8","key":"10.1016\/j.jpedsurg.2019.02.026_bb0165","doi-asserted-by":"crossref","first-page":"2924","DOI":"10.1172\/JCI83189","article-title":"Lymphatic vessel development: fluid flow and valve-forming cells","volume":"125","author":"Kume","year":"2015","journal-title":"J Clin Invest"},{"issue":"20","key":"10.1016\/j.jpedsurg.2019.02.026_bb0170","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1101\/gad.16974811","article-title":"Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves","volume":"25","author":"Srinivasan","year":"2011","journal-title":"Genes Dev"},{"issue":"6","key":"10.1016\/j.jpedsurg.2019.02.026_bb0175","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1093\/emboj\/20.6.1223","article-title":"Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice","volume":"20","author":"Veikkola","year":"2001","journal-title":"EMBO J"},{"issue":"17","key":"10.1016\/j.jpedsurg.2019.02.026_bb0180","doi-asserted-by":"crossref","first-page":"4762","DOI":"10.1093\/emboj\/20.17.4762","article-title":"Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C\/D receptor VEGFR-3","volume":"20","author":"M\u00e4kinen","year":"2001","journal-title":"EMBO J"},{"issue":"4","key":"10.1016\/j.jpedsurg.2019.02.026_bb0185","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1097\/MOG.0b013e3283476e8f","article-title":"Role of the lymphatic system in the pathogenesis of Crohn's disease","volume":"27","author":"von der Weid","year":"2011","journal-title":"Curr Opin Gastroenterol"},{"issue":"5","key":"10.1016\/j.jpedsurg.2019.02.026_bb0190","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1111\/j.1365-2036.2011.04759.x","article-title":"Increased lymphatic vessel density and lymphangiogenesis in inflammatory bowel disease","volume":"34","author":"Rahier","year":"2011","journal-title":"Aliment Pharmacol Ther"},{"issue":"10","key":"10.1016\/j.jpedsurg.2019.02.026_bb0195","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1097\/MIB.0b013e3182971cec","article-title":"Decreased lymphatic vessel density is associated with postoperative endoscopic recurrence in Crohn\u2019s Disease","volume":"19","author":"Rahier","year":"2013","journal-title":"Inflamm Bowel Dis"},{"issue":"6","key":"10.1016\/j.jpedsurg.2019.02.026_bb0200","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1016\/j.surg.2016.07.018","article-title":"Liver steatosis induced by small bowel resection is prevented by oral vancomycin","volume":"160","author":"Barron","year":"2016","journal-title":"Surgery"}],"container-title":["Journal of Pediatric Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346819301678?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346819301678?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T08:33:03Z","timestamp":1758357183000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022346819301678"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":40,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["S0022346819301678"],"URL":"https:\/\/doi.org\/10.1016\/j.jpedsurg.2019.02.026","relation":{},"ISSN":["0022-3468"],"issn-type":[{"value":"0022-3468","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lymphatic network remodeling after small bowel resection","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpedsurg.2019.02.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}