{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T20:06:54Z","timestamp":1762027614482,"version":"build-2065373602"},"reference-count":31,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpedsurg.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric Surgery"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.jpedsurg.2020.11.021","type":"journal-article","created":{"date-parts":[[2020,11,26]],"date-time":"2020-11-26T12:07:19Z","timestamp":1606392439000},"page":"2037-2044","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Long-term protective effects of the combination of intermittent reperfusion and hypothermia on reperfusion injury in an experimental testicular torsion model"],"prefix":"10.1016","volume":"56","author":[{"given":"Ali Onur","family":"Erdem","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sezen","family":"Ozkisacik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bayram","family":"Mersinli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferhat","family":"\u015eirinyildiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rauf","family":"Ek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nil","family":"Culhaci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mesut","family":"Yazici","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0001","first-page":"26","article-title":"Oxidative stress, male infertility and the role of carnitines","volume":"47","author":"Dokmeci","year":"2005","journal-title":"Folia Med (Plovdiv.)"},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0002","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.mam.2004.02.020","article-title":"Spermatic cord torsion, reactive oxygen and nitrogen species and ischemia-reperfusion injury","volume":"25","author":"Filho","year":"2004","journal-title":"Mol.Aspects Med"},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0003","doi-asserted-by":"crossref","unstructured":"Gold D.D., Lorber A., Levine H. et\u00a0al. Door to detorsion time determines testicular survival. Urology 2019.","DOI":"10.1016\/j.urology.2019.08.003"},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0004","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.bjps.2007.05.017","article-title":"Impact of gradual blood flow increase on ischaemia-reperfusion injury in the rat cremaster microcirculation model","volume":"61","author":"Ozmen","year":"2008","journal-title":"J.Plast.Reconstr.Aesthet.Surg."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0005","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1093\/bmb\/ldh025","article-title":"Vascular ischaemia and reperfusion injury","volume":"70","author":"Eltzschig","year":"2004","journal-title":"Br.Med Bull."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0006","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1016\/j.jpedsurg.2017.07.001","article-title":"Effect of vitamin C on tissue damage and oxidative stress following tunica vaginalis flap coverage after testicular torsion","volume":"52","author":"Moghimian","year":"2017","journal-title":"J.Pediatr.Surg."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0007","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.jpurol.2016.06.002","article-title":"Protective effect of tunica albuginea incision with tunica vaginalis flap coverage on tissue damage and oxidative stress following testicular torsion: role of duration of ischemia","volume":"12","author":"Moghimian","year":"2016","journal-title":"J.Pediatr.Urol."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0008","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.urology.2012.05.031","article-title":"The predictive value of ischemia-modified albumin in long-term results of ischemia-reperfusion injury in an experimental testicular torsion model","volume":"80","author":"Mentese","year":"2012","journal-title":"Urology"},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0009","doi-asserted-by":"crossref","DOI":"10.1111\/and.12673","article-title":"Effects of oral zinc administration on long-term ipsilateral and contralateral testes damage after experimental testis ischaemia-reperfusion","volume":"49","author":"Oral","year":"2017","journal-title":"Andrologia"},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0010","doi-asserted-by":"crossref","unstructured":"Erdem A.O., Coskun O.D., Baser A.T. et\u00a0al. Comparison of the effects of intermittent reperfusion and hypothermia in preventing testicular ischemia-reperfusion injury in the testicular torsion model in rats. J.Pediatr.Urol. 2019.","DOI":"10.1016\/j.jpurol.2019.09.013"},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0011","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/j.1939-4640.1986.tb00862.x","article-title":"Histopathology of prepubertal rat testes subjected to various durations of spermatic cord torsion","volume":"7","author":"Cosentino","year":"1986","journal-title":"J.Androl"},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0012","first-page":"1739","article-title":"Testicular torsion","volume":"74","author":"Ringdahl","year":"2006","journal-title":"Am.Fam.Physician"},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0013","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/iju.13110","article-title":"Testicular torsion-detorsion and potential therapeutic treatments: a possible role for ischemic postconditioning","volume":"23","author":"Shimizu","year":"2016","journal-title":"Int.J.Urol."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0014","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1530\/jrf.0.0980187","article-title":"Adenosine analogues with specificity for A2 receptors bind to mouse spermatozoa and stimulate adenylate cyclase activity in uncapacitated suspensions","volume":"98","author":"Fraser","year":"1993","journal-title":"J.Reprod.Fertil."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0015","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1111\/j.1439-0272.2009.01028.x","article-title":"Effects of co-administration of dopamine and vitamin C on ischaemia-reperfusion injury after experimental testicular torsion-detorsion in rats","volume":"43","author":"Azizollahi","year":"2011","journal-title":"Andrologia"},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0016","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/s00204-007-0189-2","article-title":"Protective effects of ibuprofen on testicular torsion\/detorsion-induced ischemia\/reperfusion injury in rats","volume":"81","author":"Dokmeci","year":"2007","journal-title":"Arch.Toxicol."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0017","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s00240-004-0436-4","article-title":"Raxofelast, a hydrophilic vitamin E-like antioxidant, reduces testicular ischemia-reperfusion injury","volume":"32","author":"Romeo","year":"2004","journal-title":"Urol.Res."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0018","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1111\/j.1464-410X.2009.08798.x","article-title":"Protective effect of edaravone, a free-radical scavenger, on ischaemia-reperfusion injury in the rat testis","volume":"105","author":"Tamamura","year":"2010","journal-title":"BJU.Int."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0019","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1016\/S0929-693X(98)80138-3","article-title":"[Acute scrotum in the child]","volume":"5","author":"Dubois","year":"1998","journal-title":"Arch.Pediatr."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0020","doi-asserted-by":"crossref","first-page":"e13471","DOI":"10.1111\/and.13471","article-title":"Predictive value of ischaemia-modified albumin in spermatogenesis in an experimental testicular torsion model","volume":"52","author":"Kutluhan","year":"2020","journal-title":"Andrologia"},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0021","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.urology.2013.09.027","article-title":"Interleukin 10 reduces testicular damage in experimental testicular ischemia\/reperfusion injury","volume":"83","author":"Ozturk","year":"2014","journal-title":"Urology"},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0022","first-page":"32","article-title":"The effect of tunica albuginea incision on testicular tissue after detorsion in the experimental model of testicular torsion","volume":"15","author":"Gultekin","year":"2018","journal-title":"Urol.J."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0023","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.jpedsurg.2011.10.070","article-title":"The long-term protective effects of short-interval postconditioning in testicular ischemia-reperfusion injury in rats","volume":"47","author":"Ozkisacik","year":"2012","journal-title":"J.Pediatr.Surg."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0024","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.jpedsurg.2010.08.056","article-title":"The effects of short-interval postconditioning in preventing testicular ischemia-reperfusion injury in rats","volume":"46","author":"Ozkisacik","year":"2011","journal-title":"J.Pediatr.Surg."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0025","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1016\/j.jpedsurg.2008.02.011","article-title":"Gradual detorsion of torsioned rat testis attenuates ischemia reperfusion injury","volume":"43","author":"Akcora","year":"2008","journal-title":"J.Pediatr.Surg."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0026","first-page":"61","article-title":"Kidney transplantation: a review of recent trends","volume":"44","author":"Humphries","year":"1978","journal-title":"Am.Surg."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0027","first-page":"196","article-title":"Renal metabolism and blood flow during local hypothermia, studied by means of renal perfusion in situ","volume":"253","author":"SEMB","year":"1960","journal-title":"Acta Chir Scand.Suppl"},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0028","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/S0022-5347(17)41074-3","article-title":"Scrotal cooling and testicular torsion","volume":"141","author":"Boyarsky","year":"1989","journal-title":"J.Urol."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0029","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/S0022-5347(17)40180-7","article-title":"Effects of hypothermia on testicular ischemia","volume":"143","author":"Miller","year":"1990","journal-title":"J.Urol."},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0030","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/S0736-4679(96)00144-8","article-title":"Testicular torsion: why not cool ischemic tissue?","volume":"14","author":"Uner","year":"1996","journal-title":"J.Emerg.Med"},{"key":"10.1016\/j.jpedsurg.2020.11.021_bib0031","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.jpurol.2018.09.017","article-title":"A systematic review and meta-analysis revealing realistic outcomes following paediatric torsion of testes","volume":"14","author":"MacDonald","year":"2018","journal-title":"J.Pediatr.Urol."}],"container-title":["Journal of Pediatric Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346820308538?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022346820308538?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T08:41:28Z","timestamp":1758357688000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022346820308538"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":31,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S0022346820308538"],"URL":"https:\/\/doi.org\/10.1016\/j.jpedsurg.2020.11.021","relation":{},"ISSN":["0022-3468"],"issn-type":[{"type":"print","value":"0022-3468"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-term protective effects of the combination of intermittent reperfusion and hypothermia on reperfusion injury in an experimental testicular torsion model","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpedsurg.2020.11.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}