{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:00:02Z","timestamp":1786993202330,"version":"build-2736575974"},"reference-count":63,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:00:00Z","timestamp":1788048000000},"content-version":"am","delay-in-days":363,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100017540","name":"National Heart Lung and Blood Institute Division of Intramural Research","doi-asserted-by":"publisher","award":["R01-HL139887"],"award-info":[{"award-number":["R01-HL139887"]}],"id":[{"id":"10.13039\/100017540","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017540","name":"National Heart Lung and Blood Institute Division of Intramural Research","doi-asserted-by":"publisher","award":["R01-HL136560"],"award-info":[{"award-number":["R01-HL136560"]}],"id":[{"id":"10.13039\/100017540","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["PXD061662"],"award-info":[{"award-number":["PXD061662"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"NIH National Institute of General Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jpet.aspetjournals.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.jpet.2025.103673","type":"journal-article","created":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T23:13:47Z","timestamp":1754694827000},"page":"103673","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Human myocardial-derived highly proliferative cells improve cardiac remodeling after myocardial infarction in mice"],"prefix":"10.1016","volume":"392","author":[{"given":"Michayla","family":"Moore","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Chepurko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vadim","family":"Chepurko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Calvin","family":"Vary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7930-9814","authenticated-orcid":false,"given":"Sergey","family":"Ryzhov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7584-0700","authenticated-orcid":false,"given":"Douglas B.","family":"Sawyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.jpet.2025.103673_bib1","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1001\/jamacardio.2016.2225","article-title":"Adult stem cell therapy and heart failure, 2000 to 2016: a systematic review","volume":"1","author":"Nguyen","year":"2016","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.jpet.2025.103673_bib2","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.yjmcc.2017.12.013","article-title":"ErbB2 promotes endothelial phenotype of human left ventricular epicardial highly proliferative cells (eHiPC)","volume":"115","author":"Ryzhov","year":"2018","journal-title":"J Mol Cell Cardiol"},{"issue":"2","key":"10.1016\/j.jpet.2025.103673_bib3","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0118168","article-title":"The Notch signaling regulates CD105 expression, osteogenic differentiation and immunomodulation of human umbilical cord mesenchymal stem cells","volume":"10","author":"Na","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.jpet.2025.103673_bib4","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/698076","article-title":"Human mesenchymal stem cells display reduced expression of CD105 after culture in serum-free medium","volume":"2013","author":"Mark","year":"2013","journal-title":"Stem Cells Int"},{"issue":"1","key":"10.1016\/j.jpet.2025.103673_bib5","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1006\/dbio.1999.9534","article-title":"Endoglin, an ancillary TGF\u03b2 receptor, is required for extraembryonic angiogenesis and plays a key role in heart development","volume":"217","author":"Arthur","year":"2000","journal-title":"Dev Biol"},{"issue":"5","key":"10.1016\/j.jpet.2025.103673_bib6","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/j.stemcr.2017.04.015","article-title":"Cardiosphere-derived cells require endoglin for paracrine-mediated angiogenesis","volume":"8","author":"Redgrave","year":"2017","journal-title":"Stem Cell Rep"},{"issue":"4","key":"10.1016\/j.jpet.2025.103673_bib7","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1161\/CIRCULATIONAHA.110.971622","article-title":"Characterization and functionality of cardiac progenitor cells in congenital heart patients","volume":"123","author":"Mishra","year":"2011","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.jpet.2025.103673_bib8","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.ijcard.2006.03.028","article-title":"Transplantation of mesenchymal stem cells from human bone marrow improves damaged heart function in rats","volume":"115","author":"Hou","year":"2007","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.jpet.2025.103673_bib9","doi-asserted-by":"crossref","first-page":"371","DOI":"10.3389\/fendo.2019.00371","article-title":"Role of c-Kit in myocardial regeneration and aging","volume":"10","author":"Marino","year":"2019","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"3","key":"10.1016\/j.jpet.2025.103673_bib10","doi-asserted-by":"crossref","first-page":"122","DOI":"10.33696\/Signaling.5.119","article-title":"ALK1 signaling in human cardiac progenitor cells promotes a pro-angiogenic secretome","volume":"5","author":"Moore","year":"2024","journal-title":"J Cell Signal"},{"issue":"20","key":"10.1016\/j.jpet.2025.103673_bib11","doi-asserted-by":"crossref","first-page":"4263","DOI":"10.1182\/blood-2012-07-440784","article-title":"BMP9 regulates endoglin-dependent chemokine responses in endothelial cells","volume":"120","author":"Young","year":"2012","journal-title":"Blood"},{"issue":"9","key":"10.1016\/j.jpet.2025.103673_bib12","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1074\/mcp.T600050-MCP200","article-title":"The Paragon Algorithm, a next generation search engine that uses sequence temperature values and feature probabilities to identify peptides from tandem mass spectra","volume":"6","author":"Shilov","year":"2007","journal-title":"Mol Cell Proteomics"},{"issue":"9","key":"10.1016\/j.jpet.2025.103673_bib13","doi-asserted-by":"crossref","first-page":"3661","DOI":"10.1021\/pr070492f","article-title":"Nonlinear fitting method for determining local false discovery rates from decoy database searches","volume":"7","author":"Tang","year":"2008","journal-title":"J Proteome Res"},{"issue":"3","key":"10.1016\/j.jpet.2025.103673_bib14","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1038\/nprot.2015.015","article-title":"Building high-quality assay libraries for targeted analysis of SWATH MS data","volume":"10","author":"Schubert","year":"2015","journal-title":"Nat Protoc"},{"issue":"13","key":"10.1016\/j.jpet.2025.103673_bib15","doi-asserted-by":"crossref","first-page":"4933","DOI":"10.1021\/ac800110w","article-title":"Dimensionality reduction and visualization in principal component analysis","volume":"80","author":"Ivosev","year":"2008","journal-title":"Anal Chem"},{"issue":"12","key":"10.1016\/j.jpet.2025.103673_bib16","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1038\/nmeth.2702","article-title":"Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition","volume":"10","author":"Lambert","year":"2013","journal-title":"Nat Methods"},{"issue":"D1","key":"10.1016\/j.jpet.2025.103673_bib17","doi-asserted-by":"crossref","first-page":"D543","DOI":"10.1093\/nar\/gkab1038","article-title":"The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences","volume":"50","author":"Perez-Riverol","year":"2022","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.jpet.2025.103673_bib18","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/1471-2105-10-48","article-title":"GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists","volume":"10","author":"Eden","year":"2009","journal-title":"BMC Bioinformatics"},{"issue":"1","key":"10.1016\/j.jpet.2025.103673_bib19","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s00395-022-00913-y","article-title":"Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing","volume":"117","author":"Kogan","year":"2022","journal-title":"Basic Res Cardiol"},{"issue":"14","key":"10.1016\/j.jpet.2025.103673_bib20","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1093\/bioinformatics\/btm254","article-title":"GEOquery: a bridge between the Gene Expression Omnibus (GEO) and BioConductor","volume":"23","author":"Davis","year":"2007","journal-title":"Bioinformatics"},{"issue":"5","key":"10.1016\/j.jpet.2025.103673_bib21","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/nbt.3192","article-title":"Spatial reconstruction of single-cell gene expression data","volume":"33","author":"Satija","year":"2015","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.jpet.2025.103673_bib22","series-title":"Robust Methods for Inferring Cluster Structure in Single Cell RNA Sequencing Data","author":"Willie","year":"2020"},{"issue":"11","key":"10.1016\/j.jpet.2025.103673_bib23","doi-asserted-by":"crossref","first-page":"H1773","DOI":"10.1152\/ajpheart.00887.2015","article-title":"Effects of vitamin A deficiency in the postnatal mouse heart: role of hepatic retinoid stores","volume":"310","author":"Asson-Batres","year":"2016","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"3","key":"10.1016\/j.jpet.2025.103673_bib24","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.ajpath.2013.05.012","article-title":"Adenosine A2B receptors on cardiac stem cell antigen (Sca)-1\u2013positive stromal cells play a protective role in myocardial infarction","volume":"183","author":"Ryzhov","year":"2013","journal-title":"Am J Pathol"},{"issue":"3","key":"10.1016\/j.jpet.2025.103673_bib25","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1124\/jpet.111.190835","article-title":"Role of A2B adenosine receptors in regulation of paracrine functions of stem cell antigen 1-positive cardiac stromal cells","volume":"341","author":"Ryzhov","year":"2012","journal-title":"J Pharmacol Exp Ther"},{"issue":"6","key":"10.1016\/j.jpet.2025.103673_bib26","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1152\/japplphysiol.00033.2007","article-title":"Myocardial infarct size measurement in the mouse chronic infarction model: comparison of area- and length-based approaches","volume":"102","author":"Takagawa","year":"2007","journal-title":"J Appl Physiol (1985)"},{"issue":"5","key":"10.1016\/j.jpet.2025.103673_bib27","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1161\/CIRCRESAHA.116.309782","article-title":"A deep proteome analysis identifies the complete secretome as the functional unit of human cardiac progenitor cells","volume":"120","author":"Sharma","year":"2017","journal-title":"Circ Res"},{"issue":"9","key":"10.1016\/j.jpet.2025.103673_bib28","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1002\/sctm.20-0509","article-title":"Secretome signature of cardiopoietic cells echoed in rescued infarcted heart proteome","volume":"10","author":"Arrell","year":"2021","journal-title":"Stem Cells Transl Med"},{"issue":"1","key":"10.1016\/j.jpet.2025.103673_bib29","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-11976-6","article-title":"CXCL6 is an important paracrine factor in the pro-angiogenic human cardiac progenitor-like cell secretome","volume":"7","author":"Tor\u00e1n","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.jpet.2025.103673_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2024.103293","article-title":"CREG1 attenuates doxorubicin-induced cardiotoxicity by inhibiting the ferroptosis of cardiomyocytes","volume":"75","author":"Liu","year":"2024","journal-title":"Redox Biol"},{"issue":"4","key":"10.1016\/j.jpet.2025.103673_bib31","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.116.003346","article-title":"Adenosine formed by CD73 on T cells inhibits cardiac inflammation and fibrosis and preserves contractile function in transverse aortic constriction\u2013induced heart failure","volume":"10","author":"Quast","year":"2017","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.jpet.2025.103673_bib32","article-title":"CD73+ mesenchymal stem cells ameliorate myocardial infarction by promoting angiogenesis","volume":"9","author":"Li","year":"2021","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.jpet.2025.103673_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.vph.2023.107246","article-title":"Activated CTHRC1 promotes glycolysis in endothelial cells: implications for metabolism and angiogenesis","volume":"153","author":"Toomey","year":"2023","journal-title":"Vascul Pharmacol"},{"issue":"11 suppl 1","key":"10.1016\/j.jpet.2025.103673_bib34","first-page":"S46","article-title":"A strong regenerative ability of cardiac stem cells derived from neonatal hearts","volume":"126","author":"Simpson","year":"2012","journal-title":"Circulation"},{"issue":"39","key":"10.1016\/j.jpet.2025.103673_bib35","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1093\/eurheartj\/ehx454","article-title":"Cardiac and systemic rejuvenation after cardiosphere-derived cell therapy in senescent rats","volume":"38","author":"Grigorian-Shamagian","year":"2017","journal-title":"Eur Heart J"},{"issue":"9","key":"10.1016\/j.jpet.2025.103673_bib36","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1111\/j.1582-4934.2011.01512.x","article-title":"Dose-dependent functional benefit of human cardiosphere transplantation in mice with acute myocardial infarction","volume":"16","author":"Shen","year":"2012","journal-title":"J Cell Mol Med"},{"issue":"7","key":"10.1016\/j.jpet.2025.103673_bib37","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1016\/j.jacc.2005.05.079","article-title":"Improved graft mesenchymal stem cell survival in ischemic heart with a hypoxia-regulated heme oxygenase-1 vector","volume":"46","author":"Tang","year":"2005","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"10.1016\/j.jpet.2025.103673_bib38","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0096725","article-title":"c-Kit+ cardiac stem cells alleviate post-myocardial infarction left ventricular dysfunction despite poor engraftment and negligible retention in the recipient heart","volume":"9","author":"Hong","year":"2014","journal-title":"PLoS One"},{"issue":"28","key":"10.1016\/j.jpet.2025.103673_bib39","article-title":"Cell granularity reflects immune cell function and enables selection of lymphocytes with superior attributes for immunotherapy","volume":"10","author":"Wu","year":"2023","journal-title":"Adv Sci (Weinh)"},{"issue":"1","key":"10.1016\/j.jpet.2025.103673_bib40","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.jchf.2013.08.008","article-title":"Human cardiosphere-derived cells from advanced heart failure patients exhibit augmented functional potency in myocardial repair","volume":"2","author":"Cheng","year":"2014","journal-title":"JACC Heart Fail"},{"issue":"2","key":"10.1016\/j.jpet.2025.103673_bib41","doi-asserted-by":"crossref","DOI":"10.1136\/openhrt-2021-001614","article-title":"Effect of cardiosphere-derived cells on segmental myocardial function after myocardial infarction: ALLSTAR randomised clinical trial","volume":"8","author":"Ostovaneh","year":"2021","journal-title":"Open Heart"},{"issue":"9819","key":"10.1016\/j.jpet.2025.103673_bib42","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/S0140-6736(12)60195-0","article-title":"Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial","volume":"379","author":"Makkar","year":"2012","journal-title":"Lancet"},{"issue":"10329","key":"10.1016\/j.jpet.2025.103673_bib43","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/S0140-6736(22)00012-5","article-title":"Repeated intravenous cardiosphere-derived cell therapy in late-stage Duchenne muscular dystrophy (HOPE-2): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial","volume":"399","author":"McDonald","year":"2022","journal-title":"Lancet"},{"issue":"9","key":"10.1016\/j.jpet.2025.103673_bib44","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0007195","article-title":"Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue","volume":"4","author":"Davis","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.jpet.2025.103673_bib45","doi-asserted-by":"crossref","first-page":"307","DOI":"10.3389\/fphar.2019.00307","article-title":"Activation of CXCL6\/CXCR1\/2 axis promotes the growth and metastasis of osteosarcoma cells in vitro and in vivo","volume":"10","author":"Liu","year":"2019","journal-title":"Front Pharmacol"},{"issue":"16","key":"10.1016\/j.jpet.2025.103673_bib46","doi-asserted-by":"crossref","first-page":"11658","DOI":"10.1074\/jbc.M607705200","article-title":"Murine CXCR1 is a functional receptor for GCP-2\/CXCL6 and interleukin-8\/CXCL8","volume":"282","author":"Fan","year":"2007","journal-title":"J Biol Chem"},{"key":"10.1016\/j.jpet.2025.103673_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2022.108257","article-title":"Targeting CXCR1 and CXCR2 receptors in cardiovascular diseases","volume":"237","author":"Dhayni","year":"2022","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.jpet.2025.103673_bib48","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/8717694","article-title":"CD73 expression on mesenchymal stem cells dictates the reparative properties via its anti-inflammatory activity","volume":"2019","author":"Tan","year":"2019","journal-title":"Stem Cells Int"},{"issue":"13","key":"10.1016\/j.jpet.2025.103673_bib49","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.010874","article-title":"Number of circulating CD73-expressing lymphocytes correlates with survival after cardiac arrest","volume":"8","author":"Ryzhov","year":"2019","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.jpet.2025.103673_bib50","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.3389\/fimmu.2017.01577","article-title":"Mesenchymal stem cells induce expression of CD73 in human monocytes in vitro and in a swine model of myocardial infarction in vivo","volume":"8","author":"Mongui\u00f3-Tortajada","year":"2017","journal-title":"Front Immunol"},{"issue":"1","key":"10.1016\/j.jpet.2025.103673_bib51","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1124\/mol.113.088567","article-title":"Role of JunB in adenosine A2B receptor\u2013mediated vascular endothelial growth factor production","volume":"85","author":"Ryzhov","year":"2014","journal-title":"Mol Pharmacol"},{"issue":"3","key":"10.1016\/j.jpet.2025.103673_bib52","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1161\/CIRCRESAHA.107.158147","article-title":"Adenosine receptor\u2013mediated adhesion of endothelial progenitors to cardiac microvascular endothelial cells","volume":"102","author":"Ryzhov","year":"2008","journal-title":"Circ Res"},{"issue":"19","key":"10.1016\/j.jpet.2025.103673_bib53","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1161\/CIRCULATIONAHA.119.044557","article-title":"Single-cell RNA sequencing analysis reveals a crucial role for CTHRC1 (collagen triple helix repeat containing 1) cardiac fibroblasts after myocardial infarction","volume":"142","author":"Ruiz-Villalba","year":"2020","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.jpet.2025.103673_bib54","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.7150\/ijbs.79260","article-title":"Cthrc1 deficiency aggravates wound healing and promotes cardiac rupture after myocardial infarction via non-canonical WNT5A signaling pathway","volume":"19","author":"Wang","year":"2023","journal-title":"Int J Biol Sci"},{"key":"10.1016\/j.jpet.2025.103673_bib55","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.765768","article-title":"The role of CXC chemokines in cardiovascular diseases","volume":"12","author":"Lu","year":"2022","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.jpet.2025.103673_bib56","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1159\/000353358","article-title":"Neutrophil-derived cytokines involved in physiological and pathological angiogenesis","volume":"99","author":"Tecchio","year":"2014","journal-title":"Chem Immunol Allergy"},{"issue":"9","key":"10.1016\/j.jpet.2025.103673_bib57","doi-asserted-by":"crossref","first-page":"2502","DOI":"10.1002\/stem.1743","article-title":"Complement component 3 is necessary to preserve myocardium and myocardial function in chronic myocardial infarction","volume":"32","author":"Wysoczynski","year":"2014","journal-title":"Stem Cells"},{"issue":"9","key":"10.1016\/j.jpet.2025.103673_bib58","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1038\/sj.leu.2403446","article-title":"Transplantation studies in C3-deficient animals reveal a novel role of the third complement component (C3) in engraftment of bone marrow cells","volume":"18","author":"Ratajczak","year":"2004","journal-title":"Leukemia"},{"issue":"9","key":"10.1016\/j.jpet.2025.103673_bib59","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1161\/CIRCULATIONAHA.119.045116","article-title":"Agrin promotes coordinated therapeutic processes leading to improved cardiac repair in pigs","volume":"142","author":"Baehr","year":"2020","journal-title":"Circulation"},{"issue":"7662","key":"10.1016\/j.jpet.2025.103673_bib60","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nature22978","article-title":"The extracellular matrix protein agrin promotes heart regeneration in mice","volume":"547","author":"Bassat","year":"2017","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.jpet.2025.103673_bib61","first-page":"520","article-title":"Release of VEGF and BMP9 from injectable alginate based composite hydrogel for treatment of myocardial infarction","volume":"6","author":"Wu","year":"2021","journal-title":"Bioact Mater"},{"issue":"12","key":"10.1016\/j.jpet.2025.103673_bib62","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1161\/CIRCRESAHA.118.312978","article-title":"Rationale and design of the CONCERT-HF trial (combination of mesenchymal and c-kit+ cardiac stem cells as regenerative therapy for heart failure)","volume":"122","author":"Bolli","year":"2018","journal-title":"Circ Res"},{"issue":"9","key":"10.1016\/j.jpet.2025.103673_bib63","doi-asserted-by":"crossref","first-page":"2020","DOI":"10.1161\/ATVBAHA.115.306142","article-title":"BMP9 induces cord blood\u2013derived endothelial progenitor cell differentiation and ischemic neovascularization via ALK1","volume":"35","author":"Kim","year":"2015","journal-title":"Arterioscler Thromb Vasc Biol"}],"container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022356525398861?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022356525398861?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:15:50Z","timestamp":1777943750000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022356525398861"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":63,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["S0022356525398861"],"URL":"https:\/\/doi.org\/10.1016\/j.jpet.2025.103673","relation":{},"ISSN":["0022-3565"],"issn-type":[{"value":"0022-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Human myocardial-derived highly proliferative cells improve cardiac remodeling after myocardial infarction in mice","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pharmacology and Experimental Therapeutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpet.2025.103673","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 American Society for Pharmacology and Experimental Therapeutics. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"103673"}}