{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:09:11Z","timestamp":1790701751908,"version":"4.1.0"},"reference-count":54,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82303230"],"award-info":[{"award-number":["82303230"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jpet.aspetjournals.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.jpet.2026.104995","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T23:23:58Z","timestamp":1785281038000},"page":"104995","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["CircDOPEY2 promotes prostate cancer metastasis via inhibiting heterogeneous nuclear ribonucleoprotein M ubiquitination to stabilize intercellular adhesion molecule 2 mRNA"],"prefix":"10.1016","volume":"393","author":[{"given":"Dingchang","family":"Shao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufeng","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinke","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingkun","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuefeng","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziwei","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dunsheng","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoxiong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jpet.2026.104995_bib1","article-title":"Cancer statistics, 2026","volume":"76","author":"Siegel","year":"2026","journal-title":"CA Cancer J Clin"},{"issue":"3","key":"10.1016\/j.jpet.2026.104995_bib2","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s11912-023-01374-9","article-title":"Multimodality therapies for localized prostate cancer","volume":"25","author":"Valle","year":"2023","journal-title":"Curr Oncol Rep"},{"issue":"5","key":"10.1016\/j.jpet.2026.104995_bib3","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.eururo.2025.06.013","article-title":"Novel therapeutic strategies for metastatic prostate cancer care","volume":"88","author":"Cimadamore","year":"2025","journal-title":"Eur Urol"},{"issue":"38","key":"10.1016\/j.jpet.2026.104995_bib4","doi-asserted-by":"crossref","first-page":"2783","DOI":"10.1038\/s41388-023-02780-w","article-title":"Going circular: history, present, and future of circRNAs in cancer","volume":"42","author":"Pisignano","year":"2023","journal-title":"Oncogene"},{"issue":"6","key":"10.1016\/j.jpet.2026.104995_bib5","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1038\/s12276-024-01177-3","article-title":"Inverted Alu repeats: friends or foes in the human transcriptome","volume":"56","author":"Lee","year":"2024","journal-title":"Exp Mol Med"},{"issue":"3","key":"10.1016\/j.jpet.2026.104995_bib6","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.tig.2025.11.001","article-title":"Features and biomedical relevance of circular RNA biogenesis","volume":"42","author":"Wang","year":"2025","journal-title":"Trends Genet"},{"issue":"9","key":"10.1016\/j.jpet.2026.104995_bib7","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/s41568-024-00721-7","article-title":"Circular RNA in cancer","volume":"24","author":"Conn","year":"2024","journal-title":"Nat Rev Cancer"},{"issue":"1","key":"10.1016\/j.jpet.2026.104995_bib8","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/s42003-024-07383-z","article-title":"Mechanisms and therapeutic implications of gene expression regulation by circRNA-protein interactions in cancer","volume":"8","author":"Zhang","year":"2025","journal-title":"Commun Biol"},{"issue":"Pt 2","key":"10.1016\/j.jpet.2026.104995_bib9","article-title":"MSTCRB: predicting circRNA-RBP interaction by extracting multi-scale features based on transformer and attention mechanism","volume":"278","author":"Zhou","year":"2024","journal-title":"Int J Biol Macromol"},{"issue":"1","key":"10.1016\/j.jpet.2026.104995_bib10","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/s13073-024-01328-1","article-title":"PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression","volume":"16","author":"Lee","year":"2024","journal-title":"Genome Med"},{"issue":"20","key":"10.1016\/j.jpet.2026.104995_bib11","doi-asserted-by":"crossref","first-page":"5780","DOI":"10.1158\/0008-5472.CAN-17-1394","article-title":"Cancer-associated MORC2-mutant M276I regulates an hnRNPM-mediated CD44 splicing switch to promote invasion and metastasis in triple-negative breast cancer","volume":"78","author":"Zhang","year":"2018","journal-title":"Cancer Res"},{"key":"10.1016\/j.jpet.2026.104995_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2024.103382","article-title":"FMRP protects breast cancer cells from ferroptosis by promoting SLC7A11 alternative splicing through interacting with hnRNPM","volume":"77","author":"Wang","year":"2024","journal-title":"Redox Biol"},{"issue":"1","key":"10.1016\/j.jpet.2026.104995_bib13","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1186\/s13046-025-03498-1","article-title":"Histone lactylation-boosted AURKB facilitates colorectal cancer progression by inhibiting HNRNPM-mediated PSAT1 mRNA degradation","volume":"44","author":"Li","year":"2025","journal-title":"J Exp Clin Cancer Res"},{"key":"10.1016\/j.jpet.2026.104995_bib14","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.ebiom.2019.02.059","article-title":"hnRNPM induces translation switch under hypoxia to promote colon cancer development","volume":"41","author":"Chen","year":"2019","journal-title":"EBioMedicine"},{"issue":"1","key":"10.1016\/j.jpet.2026.104995_bib15","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1186\/s12967-023-04536-2","article-title":"Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis","volume":"21","author":"Tang","year":"2023","journal-title":"J Transl Med"},{"issue":"12","key":"10.1016\/j.jpet.2026.104995_bib16","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.1148","article-title":"Artemisitene suppresses rheumatoid arthritis progression via modulating METTL3-mediated N6-methyladenosine modification of ICAM2 mRNA in fibroblast-like synoviocytes","volume":"12","author":"Chen","year":"2022","journal-title":"Clin Transl Med"},{"issue":"39","key":"10.1016\/j.jpet.2026.104995_bib17","doi-asserted-by":"crossref","first-page":"2919","DOI":"10.1038\/s41388-023-02769-5","article-title":"ICAM2 initiates trans-blood-CSF barrier migration and stemness properties in leptomeningeal metastasis of triple-negative breast cancer","volume":"42","author":"Pan","year":"2023","journal-title":"Oncogene"},{"issue":"21","key":"10.1016\/j.jpet.2026.104995_bib18","doi-asserted-by":"crossref","first-page":"7812","DOI":"10.3390\/ijms21217812","article-title":"Circular RNAs and their linear transcripts as diagnostic and prognostic tissue biomarkers in prostate cancer after prostatectomy in combination with clinicopathological factors","volume":"21","author":"Rochow","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jpet.2026.104995_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2024.216743","article-title":"CircUBE3A(2,3,4,5) promotes adenylate-uridylate-rich binding factor 1 nuclear translocation to suppress prostate cancer metastasis","volume":"588","author":"Wei","year":"2024","journal-title":"Cancer Lett"},{"issue":"9","key":"10.1016\/j.jpet.2026.104995_bib20","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1158\/0008-5472.CAN-22-2585","article-title":"CircFNDC3B accelerates vasculature formation and metastasis in oral squamous cell carcinoma","volume":"83","author":"Li","year":"2023","journal-title":"Cancer Res"},{"issue":"12","key":"10.1016\/j.jpet.2026.104995_bib21","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1038\/nrc3628","article-title":"Crossing the endothelial barrier during metastasis","volume":"13","author":"Reymond","year":"2013","journal-title":"Nat Rev Cancer"},{"issue":"3","key":"10.1016\/j.jpet.2026.104995_bib22","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.360","article-title":"Novel circular RNA circSOBP governs amoeboid migration through the regulation of the miR-141-3p\/MYPT1\/p-MLC2 axis in prostate cancer","volume":"11","author":"Chao","year":"2021","journal-title":"Clin Transl Med"},{"issue":"1","key":"10.1016\/j.jpet.2026.104995_bib23","doi-asserted-by":"crossref","first-page":"7194","DOI":"10.1038\/ncomms8194","article-title":"eIF1A augments Ago2-mediated dicer-independent miRNA biogenesis and RNA interference","volume":"6","author":"Yi","year":"2015","journal-title":"Nat Commun"},{"issue":"3","key":"10.1016\/j.jpet.2026.104995_bib24","first-page":"229","article-title":"Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"74","author":"Bray","year":"2024","journal-title":"CA Cancer J Clin"},{"issue":"8","key":"10.1016\/j.jpet.2026.104995_bib25","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1056\/NEJMoa2214676","article-title":"Rucaparib or physician\u2019s choice in metastatic prostate cancer","volume":"388","author":"Fizazi","year":"2023","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jpet.2026.104995_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.drup.2024.101158","article-title":"Acetate utilization promotes hormone therapy resistance in prostate cancer through neuroendocrine differentiation","volume":"77","author":"Gao","year":"2024","journal-title":"Drug Resist Updat"},{"issue":"1","key":"10.1016\/j.jpet.2026.104995_bib27","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1186\/s12967-024-05562-4","article-title":"CircRNA as an Achilles heel of cancer: characterization, biomarker and therapeutic modalities","volume":"22","author":"Zhang","year":"2024","journal-title":"J Transl Med"},{"issue":"1","key":"10.1016\/j.jpet.2026.104995_bib28","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s12943-023-01766-2","article-title":"The function and mechanisms of action of circular RNAs in urologic cancer","volume":"22","author":"Zhang","year":"2023","journal-title":"Mol Cancer"},{"issue":"1","key":"10.1016\/j.jpet.2026.104995_bib29","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1186\/s12967-023-04132-4","article-title":"Circular RNA EPHA3 suppresses progression and metastasis in prostate cancer through the miR-513a-3p\/BMP2 axis","volume":"21","author":"Feng","year":"2023","journal-title":"J Transl Med"},{"issue":"1","key":"10.1016\/j.jpet.2026.104995_bib30","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s40364-023-00495-4","article-title":"EIF4A3-induced Circ_0001187 facilitates AML suppression through promoting ubiquitin-proteasomal degradation of METTL3 and decreasing m6A modification level mediated by miR-499a-5p\/RNF113A pathway","volume":"11","author":"Yang","year":"2023","journal-title":"Biomark Res"},{"issue":"46","key":"10.1016\/j.jpet.2026.104995_bib31","doi-asserted-by":"crossref","first-page":"4549","DOI":"10.1038\/s41388-025-03599-3","article-title":"Emerging roles of RNA-binding protein hnRNPM in alternative splicing regulation and UTMD mediated sh-hnRNPM\/CMBs suppress the proliferation of colorectal cancer","volume":"44","author":"Hu","year":"2025","journal-title":"Oncogene"},{"issue":"11","key":"10.1016\/j.jpet.2026.104995_bib32","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1101\/gad.241968.114","article-title":"Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing","volume":"28","author":"Xu","year":"2014","journal-title":"Genes Dev"},{"issue":"3","key":"10.1016\/j.jpet.2026.104995_bib33","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/s41419-023-05717-z","article-title":"circPTPN12 promotes the progression and sunitinib resistance of renal cancer via hnRNPM\/IL-6\/STAT3 pathway","volume":"14","author":"Shou","year":"2023","journal-title":"Cell Death Dis"},{"issue":"8","key":"10.1016\/j.jpet.2026.104995_bib34","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.molmed.2023.05.006","article-title":"The ubiquitin-proteasome system in breast cancer","volume":"29","author":"Han","year":"2023","journal-title":"Trends Mol Med"},{"key":"10.1016\/j.jpet.2026.104995_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.neo.2024.101082","article-title":"A novel regulatory axis of MSI2-AGO2\/miR-30a-3p-CGRRF1 drives cancer chemoresistance by upregulating the KRAS\/ERK pathway","volume":"59","author":"Lu","year":"2025","journal-title":"Neoplasia"},{"issue":"6","key":"10.1016\/j.jpet.2026.104995_bib36","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.70342","article-title":"LncRNA MIR503HG regulates NETs-mediated NLRP3 inflammasome activation and NSCLC metastasis by enhancing the ubiquitination of C\/EBP\u03b2","volume":"15","author":"Ye","year":"2025","journal-title":"Clin Transl Med"},{"issue":"11","key":"10.1016\/j.jpet.2026.104995_bib37","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1038\/s41419-023-06279-w","article-title":"Specific intracellular retention of circSKA3 promotes colorectal cancer metastasis by attenuating ubiquitination and degradation of SLUG","volume":"14","author":"Deng","year":"2023","journal-title":"Cell Death Dis"},{"issue":"1","key":"10.1016\/j.jpet.2026.104995_bib38","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S1074-7613(02)00266-2","article-title":"Activation of the PKB\/AKT pathway by ICAM-2","volume":"16","author":"Perez","year":"2002","journal-title":"Immunity"},{"issue":"6219","key":"10.1016\/j.jpet.2026.104995_bib39","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1038\/339061a0","article-title":"Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1","volume":"339","author":"Staunton","year":"1989","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.jpet.2026.104995_bib40","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.celrep.2012.02.001","article-title":"Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins","volume":"1","author":"Huelga","year":"2012","journal-title":"Cell Rep"},{"issue":"10","key":"10.1016\/j.jpet.2026.104995_bib41","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1261\/rna.066712.118","article-title":"Coregulation of alternative splicing by hnRNPM and ESRP1 during EMT","volume":"24","author":"Harvey","year":"2018","journal-title":"RNA"},{"key":"10.1016\/j.jpet.2026.104995_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2025.217910","article-title":"CircRHOBTB3 suppresses MAOA by promoting cytoplasmic retention of NONO to inhibit prostate cancer proliferation and metastasis","volume":"631","author":"Song","year":"2025","journal-title":"Cancer Lett"},{"issue":"1","key":"10.1016\/j.jpet.2026.104995_bib43","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s12943-025-02261-6","article-title":"CircAKT3 promotes prostate cancer proliferation and metastasis by enhancing the binding of RPS27A and RPL11","volume":"24","author":"Song","year":"2025","journal-title":"Mol Cancer"},{"key":"10.1016\/j.jpet.2026.104995_bib44","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.canlet.2021.10.021","article-title":"Circular RNA circPFKP promotes cell proliferation by activating IMPDH2 in prostate cancer","volume":"524","author":"Wang","year":"2022","journal-title":"Cancer Lett"},{"issue":"15","key":"10.1016\/j.jpet.2026.104995_bib45","doi-asserted-by":"crossref","first-page":"7507","DOI":"10.7150\/thno.59546","article-title":"Circular RNA circRHOBTB3 represses metastasis by regulating the HuR-mediated mRNA stability of PTBP1 in colorectal cancer","volume":"11","author":"Chen","year":"2021","journal-title":"Theranostics"},{"issue":"7","key":"10.1016\/j.jpet.2026.104995_bib46","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1038\/s12276-022-00806-z","article-title":"Circular RNA ROCK1, a novel circRNA, suppresses osteosarcoma proliferation and migration via altering the miR-532-5p\/PTEN axis","volume":"54","author":"Liu","year":"2022","journal-title":"Exp Mol Med"},{"issue":"3","key":"10.1016\/j.jpet.2026.104995_bib47","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1093\/nar\/gkad1138","article-title":"ESRP1 controls biogenesis and function of a large abundant multiexon circRNA","volume":"52","author":"Liu","year":"2024","journal-title":"Nucleic Acids Res"},{"issue":"11","key":"10.1016\/j.jpet.2026.104995_bib48","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2017.556","article-title":"Circular RNA expression is suppressed by androgen receptor (AR)-regulated adenosine deaminase that acts on RNA (ADAR1) in human hepatocellular carcinoma","volume":"8","author":"Shi","year":"2017","journal-title":"Cell Death Dis"},{"issue":"12","key":"10.1016\/j.jpet.2026.104995_bib49","doi-asserted-by":"crossref","first-page":"3781","DOI":"10.7150\/ijbs.85063","article-title":"Intergenic circRNA circ_0007379 inhibits colorectal cancer progression by modulating miR-320a biogenesis in a KSRP-dependent manner","volume":"19","author":"Long","year":"2023","journal-title":"Int J Biol Sci"},{"issue":"1","key":"10.1016\/j.jpet.2026.104995_bib50","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1186\/s12967-025-06547-7","article-title":"SRSF1-mediated alternative splicing regulates bladder cancer progression and cisplatin sensitivity through HIF1A\/BNIP3\/mitophagy axis","volume":"23","author":"Wu","year":"2025","journal-title":"J Transl Med"},{"issue":"7","key":"10.1016\/j.jpet.2026.104995_bib51","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1158\/2159-8290.CD-22-1013","article-title":"Splicing factor SRSF1 promotes pancreatitis and KRASG12D-mediated pancreatic cancer","volume":"13","author":"Wan","year":"2023","journal-title":"Cancer Discov"},{"issue":"1","key":"10.1016\/j.jpet.2026.104995_bib52","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/s13046-021-01931-9","article-title":"The SRSF1\/circATP5B\/miR-185-5p\/HOXB5 feedback loop regulates the proliferation of glioma stem cells via the IL6-mediated JAK2\/STAT3 signaling pathway","volume":"40","author":"Zhao","year":"2021","journal-title":"J Exp Clin Cancer Res"},{"issue":"2","key":"10.1016\/j.jpet.2026.104995_bib53","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/j.ymthe.2025.10.038","article-title":"CircRNA: unlocking new frontiers in therapeutic and vaccine development","volume":"34","author":"Bahrulolum","year":"2026","journal-title":"Mol Ther"},{"issue":"6","key":"10.1016\/j.jpet.2026.104995_bib54","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.tips.2026.04.011","article-title":"Development of RNA-targeting small-molecule therapeutics","volume":"47","author":"Zahurancik","year":"2026","journal-title":"Trends Pharmacol Sci"}],"container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002235652601195X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002235652601195X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:44:15Z","timestamp":1790700255000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002235652601195X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":54,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S002235652601195X"],"URL":"https:\/\/doi.org\/10.1016\/j.jpet.2026.104995","relation":{},"ISSN":["0022-3565"],"issn-type":[{"value":"0022-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CircDOPEY2 promotes prostate cancer metastasis via inhibiting heterogeneous nuclear ribonucleoprotein M ubiquitination to stabilize intercellular adhesion molecule 2 mRNA","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pharmacology and Experimental Therapeutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpet.2026.104995","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 American Society for Pharmacology and Experimental Therapeutics. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"104995"}}