{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T20:45:12Z","timestamp":1765485912490},"reference-count":27,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,5,26]],"date-time":"2015-05-26T00:00:00Z","timestamp":1432598400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Ministry of Education","award":["22591801"],"award-info":[{"award-number":["22591801"]}]},{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmacological Sciences"],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1016\/j.jphs.2015.05.005","type":"journal-article","created":{"date-parts":[[2015,5,28]],"date-time":"2015-05-28T21:30:08Z","timestamp":1432848608000},"page":"65-70","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["The role of muscarinic receptor subtypes on carbachol-induced contraction of normal human detrusor and overactive detrusor associated with benign prostatic hyperplasia"],"prefix":"10.1016","volume":"128","author":[{"given":"Tomonori","family":"Yamanishi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanya","family":"Kaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miki","family":"Fuse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiharu","family":"Shibata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takao","family":"Kamai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoyuki","family":"Uchiyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jphs.2015.05.005_bib1","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s003450100226","article-title":"Which muscarinic receptor is important in the bladder?","volume":"19","author":"Yamanishi","year":"2001","journal-title":"World J Urol"},{"key":"10.1016\/j.jphs.2015.05.005_bib2","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1111\/j.1464-410X.2007.07205.x","article-title":"Muscarinic receptor antagonists for overactive bladder","volume":"100","author":"Abrams","year":"2007","journal-title":"BJU Int"},{"key":"10.1016\/j.jphs.2015.05.005_bib3","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1111\/j.1464-410X.2007.07031.x","article-title":"Randomized, double-blind, placebo- and propiverine-controlled trial of the once-daily antimuscarinic agent solifenacin in Japanese patients with overactive bladder","volume":"100","author":"Yamaguchi","year":"2007","journal-title":"BJU Int"},{"key":"10.1016\/j.jphs.2015.05.005_bib4","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1111\/j.1442-2042.2008.02104.x","article-title":"A\u00a0randomized, double-blind, placebo-controlled phase II dose-finding study of the novel anti-muscarinic agent imidafenacin in Japanese patients with overactive bladder","volume":"15","author":"Homma","year":"2008","journal-title":"Int J Urol"},{"key":"10.1016\/j.jphs.2015.05.005_bib5","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/j.eururo.2007.05.027","article-title":"Treatment outcomes in the STAR study: a subanalysis of solifenacin 5 mg and tolterodine ER 4 mg","volume":"52","author":"Chapple","year":"2007","journal-title":"Eur Urol"},{"key":"10.1016\/j.jphs.2015.05.005_bib6","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1111\/bju.12678","article-title":"Superiority of fesoterodine 8 mg vs 4 mg in reducing urgency urinary incontinence episodes in patients with overactive bladder: results of the randomised, double-blind, placebo-controlled EIGHT trial","volume":"114","author":"Chapple","year":"2014","journal-title":"BJU Int"},{"key":"10.1016\/j.jphs.2015.05.005_bib7","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1159\/000072681","article-title":"Pharmacological effects of KRP-19712, on the human isolated urinary bladder","volume":"71","author":"Murakami","year":"2003","journal-title":"Urol Int"},{"key":"10.1016\/j.jphs.2015.05.005_bib8","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1111\/luts.12068","article-title":"Cognitive safety and overall tolerability of imidafenacin in clinical use: a long-term, open-label, post-marketing surveillance study","volume":"6","author":"Sakakibara","year":"2014","journal-title":"LUTS"},{"key":"10.1016\/j.jphs.2015.05.005_bib9","first-page":"243","article-title":"The minor population of M3 receptors mediate contraction of human detrusor muscle in\u00a0vitro","volume":"21","author":"Chess-Williams","year":"2001","journal-title":"J\u00a0Auton Pharmacol"},{"key":"10.1016\/j.jphs.2015.05.005_bib10","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1038\/sj.bjp.0706147","article-title":"Muscarinic receptor subtypes in human bladder detrusor and mucosa, studied by radioligand binding and quantitative competitive RT-PCR: changes in aging","volume":"144","author":"Mansfield","year":"2005","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.jphs.2015.05.005_bib11","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1038\/sj.bjp.0703719","article-title":"The role of M2-muscarinic receptors in mediating contraction of the pig urinary bladder in\u00a0vitro","volume":"131","author":"Yamanishi","year":"2000","journal-title":"Br J Pharmachol"},{"key":"10.1016\/j.jphs.2015.05.005_bib12","first-page":"171","article-title":"M3 muscarinic receptors but not M2 mediate contraction of the porcine detrusor muscle in\u00a0vitro","volume":"20","author":"Sellers","year":"2000","journal-title":"J\u00a0Auton Pharmacol"},{"key":"10.1016\/j.jphs.2015.05.005_bib13","first-page":"397","article-title":"The role of M2 muscarinic receptor subtypes in mediating contraction of the pig bladder base after cyclic adenosine monophosphate elevation and\/or selective M3 inactivation","volume":"167","author":"Yamanishi","year":"2002","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.jphs.2015.05.005_bib14","first-page":"R1654","article-title":"M2 muscarinic receptor contributes to contraction of the denervated rat urinary bladder","volume":"275","author":"Bravermen","year":"1998","journal-title":"Am J Phys"},{"key":"10.1016\/j.jphs.2015.05.005_bib15","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S0024-3205(98)00582-7","article-title":"M2 receptors in genito-urinary smooth muscle pathology","volume":"64","author":"Braverman","year":"1999","journal-title":"Life Sci"},{"key":"10.1016\/j.jphs.2015.05.005_bib16","doi-asserted-by":"crossref","first-page":"R874","DOI":"10.1152\/ajpregu.00391.2003","article-title":"The M2 muscarinic receptor mediates in\u00a0vitro bladder contractions from patients with neurogenic bladder dysfunction","volume":"286","author":"Pontari","year":"2004","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.jphs.2015.05.005_bib17","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/nau.20180","article-title":"Muscarinic receptor transcript and protein density in hypertrophied and atrophied rat urinary bladder","volume":"25","author":"Braverman","year":"2006","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.jphs.2015.05.005_bib18","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.eururo.2006.11.016","article-title":"Human idiopathic and neurogenic overactive bladders and the role of M2 muscarinic receptors in contraction","volume":"52","author":"Stevens","year":"2007","journal-title":"Eur Urol"},{"key":"10.1016\/j.jphs.2015.05.005_bib19","first-page":"1644","article-title":"Function of M3 muscarinic receptors in the rat urinary bladder following partial outlet obstruction","volume":"161","author":"Krichevsky","year":"1999","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.jphs.2015.05.005_bib20","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1002\/nau.20802","article-title":"Urodynamic effects of silodosin, a new \u03b11A-adrenoceptor selective antagonist, for the treatment of benign prostatic hyperplasia","volume":"29","author":"Yamanishi","year":"2010","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.jphs.2015.05.005_bib21","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1046\/j.1464-410X.2003.04468.x","article-title":"Clinical efficacy and tolerability of extended-release tolterodine and immediate-release oxybutynin in Japanese and Korean patients with an overactive bladder: a randomized, placebo-controlled trial","volume":"92","author":"Homma","year":"2003","journal-title":"BJU Int"},{"key":"10.1016\/j.jphs.2015.05.005_bib22","first-page":"999","article-title":"Safety and tolerability of tolterodine for the treatment of overactive bladder in men with bladder outlet obstruction","volume":"175","author":"Abrams","year":"2006","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.jphs.2015.05.005_bib23","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1046\/j.1464-410x.2000.00892.x","article-title":"Comparison of the effects of novel antimuscarinic drugs on human detrusor smooth muscle","volume":"86","author":"Yono","year":"2000","journal-title":"BJU Int"},{"key":"10.1016\/j.jphs.2015.05.005_bib24","first-page":"92","article-title":"Effects of imidafenacin (KRP-197\/ONO-8025), a new anti-cholinergic agent, on muscarinic acetylcholine receptors. High affinities for M3 and M1 receptor subtypes and selectivity for urinary bladder over salivary gland","volume":"57","author":"Kobayashi","year":"2007","journal-title":"Arzneimittelforschung"},{"key":"10.1016\/j.jphs.2015.05.005_bib25","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1159\/000127840","article-title":"Pharmacological effects of solifenacin on human isolated urinary bladder","volume":"82","author":"Masunaga","year":"2008","journal-title":"Pharmacology"},{"key":"10.1016\/j.jphs.2015.05.005_bib26","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s00210-006-0103-0","article-title":"Propiverine and metabolites: differences in binding to muscarinic receptors and in functional models of detrusor contraction","volume":"374","author":"Wuest","year":"2006","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"issue":"5","key":"10.1016\/j.jphs.2015.05.005_bib27","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.urology.2009.12.013","article-title":"Differential roles of M2 and M3 muscarinic receptor subtypes in modulation of bladder afferent activity in rats","volume":"7","author":"Matsumoto","year":"2010","journal-title":"Urology"}],"container-title":["Journal of Pharmacological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1347861315001036?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1347861315001036?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,9]],"date-time":"2024-06-09T07:40:50Z","timestamp":1717918850000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1347861315001036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["S1347861315001036"],"URL":"https:\/\/doi.org\/10.1016\/j.jphs.2015.05.005","relation":{},"ISSN":["1347-8613"],"issn-type":[{"value":"1347-8613","type":"print"}],"subject":[],"published":{"date-parts":[[2015,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of muscarinic receptor subtypes on carbachol-induced contraction of normal human detrusor and overactive detrusor associated with benign prostatic hyperplasia","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmacological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jphs.2015.05.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 The Authors. Production and hosting by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}