{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T12:57:00Z","timestamp":1770901020200,"version":"3.50.1"},"reference-count":37,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Plant Physiology"],"published-print":{"date-parts":[[2011,4]]},"DOI":"10.1016\/j.jplph.2010.09.011","type":"journal-article","created":{"date-parts":[[2010,11,19]],"date-time":"2010-11-19T04:21:12Z","timestamp":1290140472000},"page":"576-584","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":69,"title":["Significance of phenols in cadmium and nickel uptake"],"prefix":"10.1016","volume":"168","author":[{"given":"Jozef","family":"Kov\u00e1\u010dik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo\u0159ivoj","family":"Klejdus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josef","family":"Hedbavny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerzy","family":"Zo\u0144","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jplph.2010.09.011_bib0005","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.jhazmat.2009.07.077","article-title":"Influence of nickel stress on growth and some important physiological\/biochemical attributes in some diverse canola (Brassica napus L.) cultivars","volume":"172","author":"Ali","year":"2009","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.jplph.2010.09.011_bib0010","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/0304-4165(79)90060-6","article-title":"Superinduction of phenylalanine ammonia-lyase in gherkin hypocotyls caused by the inhibitor l-\u03b1-aminooxy-\u03b2-phenylpropionic acid","volume":"583","author":"Amrhein","year":"1979","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.jplph.2010.09.011_bib0015","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/S0031-9422(02)00561-7","article-title":"Kinetic analysis of the inhibition of phenylalanine ammonia-lyase by 2-aminoindan-2-phosphonic acid and other phenylalanine analogues","volume":"62","author":"Appert","year":"2003","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jplph.2010.09.011_bib0020","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein\u2013dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal Biochem"},{"key":"10.1016\/j.jplph.2010.09.011_bib0025","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S0031-9422(03)00286-3","article-title":"Soluble and wall-bound phenolic polymers in Musa acuminata roots exposed to elicitors from Fusarium oxysporum f.sp. cubense","volume":"63","author":"de Ascensao","year":"2003","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jplph.2010.09.011_bib0030","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1002\/(SICI)1096-9888(1998110)33:11<1080::AID-JMS720>3.0.CO;2-2","article-title":"Electrospray mass spectrometry and UV\/visible spectrophotometry studies of aluminum(III)\u2013flavonoid complexes","volume":"33","author":"Deng","year":"1998","journal-title":"J Mass Spectrom"},{"key":"10.1016\/j.jplph.2010.09.011_bib0035","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.2307\/3870059","article-title":"Stress-induced phenylpropanoid metabolism","volume":"7","author":"Dixon","year":"1995","journal-title":"Plant Cell"},{"key":"10.1016\/j.jplph.2010.09.011_bib0040","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1023\/B:JOEC.0000030272.83794.f0","article-title":"Lignification and related enzymes in Glycine max root growth-inhibition by ferulic acid","volume":"30","author":"dos Santos","year":"2004","journal-title":"J Chem Ecol"},{"key":"10.1016\/j.jplph.2010.09.011_bib0045","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.plaphy.2006.08.004","article-title":"High performance liquid chromatography method for the determination of cinnamyl alcohol dehydrogenase activity in soybean roots","volume":"44","author":"dos Santos","year":"2006","journal-title":"Plant Physiol Biochem"},{"key":"10.1016\/j.jplph.2010.09.011_bib0050","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1093\/jxb\/erh092","article-title":"Effects of a PAL inhibitor on phenolic accumulation and UV-B tolerance in Spirodela intermedia (Koch.)","volume":"55","author":"Gitz","year":"2004","journal-title":"J Exp Bot"},{"key":"10.1016\/j.jplph.2010.09.011_bib0055","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S0168-9452(02)00136-X","article-title":"Constitutive elevated accumulation of phenylpropanoids in soybean roots at low temperature","volume":"163","author":"Janas","year":"2002","journal-title":"Plant Sci"},{"key":"10.1016\/j.jplph.2010.09.011_bib0060","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1007\/s11738-008-0268-x","article-title":"Induction of phenolic compounds in two dark-grown lentil cultivars with different tolerance to copper ions","volume":"31","author":"Janas","year":"2009","journal-title":"Acta Physiol Plant"},{"key":"10.1016\/j.jplph.2010.09.011_bib0065","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.jplph.2009.09.016","article-title":"The impact of copper ions on growth, lipid peroxidation and phenolic compound accumulation and localization in lentil (Lens culinaris Medic.) seedlings","volume":"167","author":"Janas","year":"2010","journal-title":"J Plant Physiol"},{"key":"10.1016\/j.jplph.2010.09.011_bib0070","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s00468-006-0117-8","article-title":"Phenolics during early development of Betula pubescens seedlings: inhibition of phenylalanine ammonia lyase","volume":"21","author":"Keski-Saari","year":"2007","journal-title":"Trees"},{"key":"10.1016\/j.jplph.2010.09.011_bib0075","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.envexpbot.2007.07.012","article-title":"Phenolic compounds composition and physiological attributes of Matricaria chamomilla grown in copper excess","volume":"62","author":"Kov\u00e1\u010dik","year":"2008","journal-title":"Environ Exp Bot"},{"key":"10.1016\/j.jplph.2010.09.011_bib0080","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s00299-007-0490-9","article-title":"Dynamics of phenolic acids and lignin accumulation in metal-treated Matricaria chamomilla roots","volume":"27","author":"Kov\u00e1\u010dik","year":"2008","journal-title":"Plant Cell Rep"},{"key":"10.1016\/j.jplph.2010.09.011_bib0085","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.foodchem.2008.04.052","article-title":"Accumulation of coumarin-related compounds in leaves of Matricaria chamomilla related to sample processing","volume":"111","author":"Kov\u00e1\u010dik","year":"2008","journal-title":"Food Chem"},{"key":"10.1016\/j.jplph.2010.09.011_bib0090","doi-asserted-by":"crossref","first-page":"9848","DOI":"10.1021\/jf902645c","article-title":"Cadmium and nickel uptake are differentially modulated by salicylic acid in Matricaria chamomilla plants","volume":"57","author":"Kov\u00e1\u010dik","year":"2009","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.jplph.2010.09.011_bib0095","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1016\/j.freeradbiomed.2009.03.020","article-title":"Nitric oxide signals ROS scavenger-mediated enhancement of PAL activity in nitrogen-deficient Matricaria chamomilla roots: side effects of scavengers","volume":"46","author":"Kov\u00e1\u010dik","year":"2009","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.jplph.2010.09.011_bib0100","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1016\/j.jplph.2009.03.002","article-title":"Phenolic metabolism of Matricaria chamomilla plants exposed to nickel","volume":"166","author":"Kov\u00e1\u010dik","year":"2009","journal-title":"J Plant Physiol"},{"key":"10.1016\/j.jplph.2010.09.011_bib0105","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s11104-009-9889-0","article-title":"Comparison of cadmium and copper effect on phenolic metabolism, mineral nutrients and stress-related parameters in Matricaria chamomilla plants","volume":"320","author":"Kov\u00e1\u010dik","year":"2009","journal-title":"Plant Soil"},{"key":"10.1016\/j.jplph.2010.09.011_bib0190","doi-asserted-by":"crossref","first-page":"10270","DOI":"10.1021\/jf101977v","article-title":"Copper uptake is differentially modulated by phenylalanine ammonia-lyase inhibition in diploid and tetraploid chamomile","volume":"58","author":"Kov\u00e1\u010dik","year":"2010","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.jplph.2010.09.011_bib0115","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1104\/pp.103.032953","article-title":"Tissue- and age-dependent differences in the complexation of cadmium and zinc in the cadmium\/zinc hyperaccumulator Thlaspi caerulescens (Ganges Ecotype) revealed by X-ray absorption spectroscopy","volume":"134","author":"K\u00fcpper","year":"2004","journal-title":"Plant Physiol"},{"key":"10.1016\/j.jplph.2010.09.011_bib0120","first-page":"31","article-title":"Nickel in the environment and its role in the metabolism of plants and cyanobacteria","volume":"vol. 2","author":"K\u00fcpper","year":"2007"},{"key":"10.1016\/j.jplph.2010.09.011_bib0125","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s00468-006-0120-0","article-title":"Restoration of secondary metabolism in birch seedlings relieved from PAL-inhibitor","volume":"21","author":"Nybakken","year":"2007","journal-title":"Trees"},{"key":"10.1016\/j.jplph.2010.09.011_bib0130","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1078\/0176-1617-00284","article-title":"Umbelliferone, a stress metabolite of Chamomilla recutita (L.) Rauschert","volume":"158","author":"Rep\u010d\u00e1k","year":"2001","journal-title":"J Plant Physiol"},{"key":"10.1016\/j.jplph.2010.09.011_bib0135","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/0891-5849(95)02227-9","article-title":"Structure\u2013antioxidant activity relationships of flavonoids and phenolic acids","volume":"20","author":"Rice-Evans","year":"1996","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.jplph.2010.09.011_bib0140","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1104\/pp.108.131524","article-title":"Cellular response of pea plants to cadmium toxicity: cross talk between reactive oxygen species, nitric oxide and calcium","volume":"150","author":"Rodr\u00edguez-Serrano","year":"2009","journal-title":"Plant Physiol"},{"key":"10.1016\/j.jplph.2010.09.011_bib0145","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1105\/tpc.104.023705","article-title":"Molecular phenotyping of the pal1 and pal2 mutants of Arabidopsis thaliana reveals far-reaching consequences on phenylpropanoid, amino acid, and carbohydrate metabolism","volume":"16","author":"Rohde","year":"2004","journal-title":"Plant Cell"},{"key":"10.1016\/j.jplph.2010.09.011_bib0150","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1023\/A:1024266612585","article-title":"Trade-off between synthesis of salicylates and growth in micropropagated Salix pentandra","volume":"29","author":"Ruuhola","year":"2003","journal-title":"J Chem Ecol"},{"key":"10.1016\/j.jplph.2010.09.011_bib0155","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0300-483X(02)00196-8","article-title":"Plant phenolic antioxidant and prooxidant activities: phenolics-induced oxidative damage mediated by metals in plants","volume":"177","author":"Sakihama","year":"2002","journal-title":"Toxicology"},{"key":"10.1016\/j.jplph.2010.09.011_bib0160","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1111\/j.0031-9317.2004.00396.x","article-title":"Phenylalanine ammonia-lyase-induced freezing tolerance in jack pine (Pinus banksiana) seedlings treated with low, ambient levels of ultraviolet-B radiation","volume":"122","author":"Teklemariam","year":"2004","journal-title":"Physiol Plant"},{"key":"10.1016\/j.jplph.2010.09.011_bib0165","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s11816-008-0052-9","article-title":"Involvement of nitric oxide-induced NADPH oxidase in adventitious root growth and antioxidant defense in Panax ginseng","volume":"2","author":"Tewari","year":"2008","journal-title":"Plant Biotechnol Rep"},{"key":"10.1016\/j.jplph.2010.09.011_bib0170","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1111\/j.1469-8137.2006.01940.x","article-title":"Subcellular localization of cadmium in roots and leaves of Arabidopsis thaliana","volume":"173","author":"van Belleghem","year":"2007","journal-title":"New Phytol"},{"key":"10.1016\/j.jplph.2010.09.011_bib0175","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.enzmictec.2004.08.038","article-title":"O2\u2212 from elicitor-induced oxidative burst is necessary for triggering phenylalanine ammonia-lyase activation and catharanthine synthesis in Catharanthus roseus cell cultures","volume":"36","author":"Xu","year":"2005","journal-title":"Enzyme Microb Technol"},{"key":"10.1016\/j.jplph.2010.09.011_bib0180","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1002\/jlac.1992199201107","article-title":"Inhibitors of phenylalanine ammonia-lyase: 2-aminoindan-2-phosphonic acid and related compounds","author":"Zo\u0144","year":"1992","journal-title":"Liebigs Ann Chem"},{"key":"10.1016\/j.jplph.2010.09.011_bib0185","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1039\/b307533h","article-title":"Experimental and ab initio calculated structures of 2-aminoindane-2-phosphonic acid, a potent inhibitor of phenylalanine ammonia-lyase, and theoretical studies of its binding to the model enzyme structure","volume":"28","author":"Zo\u0144","year":"2004","journal-title":"New J Chem"}],"container-title":["Journal of Plant Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0176161710004773?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0176161710004773?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T17:48:07Z","timestamp":1759254487000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0176161710004773"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["S0176161710004773"],"URL":"https:\/\/doi.org\/10.1016\/j.jplph.2010.09.011","relation":{},"ISSN":["0176-1617"],"issn-type":[{"value":"0176-1617","type":"print"}],"subject":[],"published":{"date-parts":[[2011,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Significance of phenols in cadmium and nickel uptake","name":"articletitle","label":"Article Title"},{"value":"Journal of Plant Physiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jplph.2010.09.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}