{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T03:50:03Z","timestamp":1791085803605,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Proteomics"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1016\/j.jprot.2012.04.028","type":"journal-article","created":{"date-parts":[[2012,4,30]],"date-time":"2012-04-30T19:30:05Z","timestamp":1335814205000},"page":"3665-3673","source":"Crossref","is-referenced-by-count":39,"title":["Human infant saliva peptidome is modified with age and diet transition"],"prefix":"10.1016","volume":"75","author":[{"given":"Martine","family":"Morzel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline","family":"Jeannin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e9raldine","family":"Lucchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Truntzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Pecqueur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Nicklaus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Chambon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Ducoroy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.jprot.2012.04.028_bb0005","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1002\/bmc.358","article-title":"Analysis of salivary peptides using HPLC\u2013electrospray mass spectrometry","volume":"18","author":"Vitorino","year":"2004","journal-title":"Biomed Chromatogr"},{"issue":"3","key":"10.1016\/j.jprot.2012.04.028_bb0010","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s10989-009-9167-2","article-title":"Mass-spectrometry based characterisation of infant whole saliva peptidome","volume":"15","author":"Lucchi","year":"2009","journal-title":"Int J Pept Res Ther"},{"issue":"8","key":"10.1016\/j.jprot.2012.04.028_bb0015","doi-asserted-by":"crossref","first-page":"2885","DOI":"10.1021\/bi048176r","article-title":"Toward defining the human parotid gland salivary proteome and peptidome: identification and characterization using 2D SDS\u2013PAGE, ultrafiltration, HPLC, and mass spectrometry","volume":"44","author":"Hardt","year":"2005","journal-title":"Biochemistry"},{"issue":"5","key":"10.1016\/j.jprot.2012.04.028_bb0020","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1074\/mcp.M700501-MCP200","article-title":"Trafficking and postsecretory events responsible for the formation of secreted human salivary peptides: a proteomics approach","volume":"7","author":"Messana","year":"2008","journal-title":"Mol Cell Proteomics"},{"issue":"6","key":"10.1016\/j.jprot.2012.04.028_bb0025","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1111\/j.1600-0722.2005.00246.x","article-title":"Peptides of human gingival crevicular fluid determined by HPLC\u2013SI\u2013MS","volume":"113","author":"Pisano","year":"2005","journal-title":"Eur J Oral Sci"},{"issue":"4","key":"10.1016\/j.jprot.2012.04.028_bb0030","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1021\/pr900775s","article-title":"Mass Spectrometric analyses of peptides and proteins in human gingival crevicular fluid","volume":"9","author":"Ngo","year":"2010","journal-title":"J Proteome Res"},{"issue":"1","key":"10.1016\/j.jprot.2012.04.028_bb0035","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1196\/annals.1384.013","article-title":"Whole saliva proteolysis. Wealth of information for diagnostic exploitation","volume":"1098","author":"Helmerhorst","year":"2007","journal-title":"Ann N Y Acad Sci"},{"issue":"20","key":"10.1016\/j.jprot.2012.04.028_bb0040","doi-asserted-by":"crossref","first-page":"3732","DOI":"10.1002\/pmic.201000261","article-title":"Finding new posttranslational modifications in salivary proline-rich proteins","volume":"10","author":"Vitorino","year":"2010","journal-title":"Proteomics"},{"issue":"12","key":"10.1016\/j.jprot.2012.04.028_bb0045","doi-asserted-by":"crossref","first-page":"5327","DOI":"10.1021\/pr8004088","article-title":"Hypo-phosphorylation of salivary peptidome as a clue to the molecular pathogenesis of autism spectrum disorders","volume":"7","author":"Castagnola","year":"2008","journal-title":"J Proteome Res"},{"issue":"1","key":"10.1016\/j.jprot.2012.04.028_bb0050","doi-asserted-by":"crossref","DOI":"10.1074\/mcp.M110.003467","article-title":"The surprising composition of the salivary proteome of preterm human newborn","volume":"10","author":"Castagnola","year":"2011","journal-title":"Mol Cell Proteomics"},{"issue":"1","key":"10.1016\/j.jprot.2012.04.028_bb0055","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1177\/154405910508400104","article-title":"Proteins in whole saliva during the first year of infancy","volume":"84","author":"Ruhl","year":"2005","journal-title":"J Dent Res"},{"issue":"7","key":"10.1016\/j.jprot.2012.04.028_bb0060","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.archoralbio.2010.12.015","article-title":"Saliva electrophoretic protein profiles in infants: changes with age and impact of teeth eruption and diet transition","volume":"56","author":"Morzel","year":"2011","journal-title":"Arch Oral Biol"},{"issue":"8","key":"10.1016\/j.jprot.2012.04.028_bb0065","doi-asserted-by":"crossref","first-page":"4126","DOI":"10.1021\/pr900212u","article-title":"Age-dependent modifications of the human salivary secretory protein complex","volume":"8","author":"Cabras","year":"2009","journal-title":"J Proteome Res"},{"key":"10.1016\/j.jprot.2012.04.028_bb0070","series-title":"Bioinformatics and Computational Biology Solutions using R and Bioconductor","first-page":"397","article-title":"Limma: linear models for microarray data","author":"Smyth","year":"2005"},{"issue":"1","key":"10.1016\/j.jprot.2012.04.028_bb0075","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate\u2014a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J R Stat Soc B Methodol"},{"issue":"14","key":"10.1016\/j.jprot.2012.04.028_bb0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v040.i14","article-title":"Factor Analysis for Multiple Testing (FAMT): an R package for large-scale significance testing under dependence","volume":"40","author":"Causeur","year":"2011","journal-title":"J Stat Softw"},{"issue":"9","key":"10.1016\/j.jprot.2012.04.028_bb0085","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1021\/ac0013709","article-title":"Charting the proteomes of organisms with unsequenced genomes by MALDI-quadrupole time of flight mass spectrometry and BLAST homology searching","volume":"73","author":"Shevchenko","year":"2001","journal-title":"Anal Chem"},{"issue":"1","key":"10.1016\/j.jprot.2012.04.028_bb0090","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1177\/00220345950740011001","article-title":"Characterization of low-molecular-weight peptides in human parotid saliva","volume":"74","author":"Perinpanayagam","year":"1995","journal-title":"J Dent Res"},{"issue":"15","key":"10.1016\/j.jprot.2012.04.028_bb0095","doi-asserted-by":"crossref","first-page":"4947","DOI":"10.1021\/ac050161r","article-title":"Assessing the effects of diurnal variation on the composition of human parotid saliva: quantitative analysis of native peptides using iTRAQ reagents","volume":"77","author":"Hardt","year":"2005","journal-title":"Anal Chem"},{"issue":"5","key":"10.1016\/j.jprot.2012.04.028_bb0100","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1002\/prca.200800183","article-title":"Towards defining the whole salivary peptidome","volume":"3","author":"Vitorino","year":"2009","journal-title":"Proteomics Clin Appl"},{"issue":"10","key":"10.1016\/j.jprot.2012.04.028_bb0105","doi-asserted-by":"crossref","first-page":"5413","DOI":"10.1021\/pr100653r","article-title":"Mass spectrometric identification of key proteolytic cleavage sites in statherin affecting mineral homeostasis and bacterial binding domains","volume":"9","author":"Helmerhorst","year":"2010","journal-title":"J Proteome Res"},{"issue":"12","key":"10.1016\/j.jprot.2012.04.028_bb0110","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.archoralbio.2006.06.005","article-title":"Oral fluid proteolytic effects on histatin 5 structure and function","volume":"51","author":"Helmerhorst","year":"2006","journal-title":"Arch Oral Biol"},{"issue":"11","key":"10.1016\/j.jprot.2012.04.028_bb0115","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1177\/0022034511420721","article-title":"Whole-saliva proteolysis and its impact on salivary diagnostics","volume":"90","author":"Thomadaki","year":"2011","journal-title":"J Dent Res"},{"issue":"40","key":"10.1016\/j.jprot.2012.04.028_bb0120","doi-asserted-by":"crossref","first-page":"41436","DOI":"10.1074\/jbc.M404322200","article-title":"A cascade of 24 histatins (Histatin 3 fragments) in human saliva: suggestions for a pre-secretory sequential cleavage pathway","volume":"279","author":"Castagnola","year":"2004","journal-title":"J Biol Chem"},{"issue":"4","key":"10.1016\/j.jprot.2012.04.028_bb0125","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1021\/pr060520e","article-title":"Proteomic analysis of salivary acidic proline-rich proteins in human preterm and at-term newborns","volume":"6","author":"Inzitari","year":"2007","journal-title":"J Proteome Res"},{"issue":"29","key":"10.1016\/j.jprot.2012.04.028_bb0130","doi-asserted-by":"crossref","first-page":"19957","DOI":"10.1074\/jbc.M708282200","article-title":"Identification of Lys\u2013Pro\u2013Gln as a novel cleavage site specificity of saliva-associated proteases","volume":"283","author":"Helmerhorst","year":"2008","journal-title":"J Biol Chem"},{"issue":"4","key":"10.1016\/j.jprot.2012.04.028_bb0135","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.1875-595X.2006.tb00107.x","article-title":"The oral microflora\u2014friend or foe? Can we decide?","volume":"56","author":"Marsh","year":"2006","journal-title":"Int Dent J"},{"issue":"11","key":"10.1016\/j.jprot.2012.04.028_bb0140","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/0003-9969(93)90113-Z","article-title":"The influence of histatin-5 fragments on the mineralization of hydroxyapatite","volume":"38","author":"Richardson","year":"1993","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.jprot.2012.04.028_bb0145","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1042\/bj2840557","article-title":"Formation of salivary-mucosal pellicle\u2014the role of transglutaminase","volume":"284","author":"Bradway","year":"1992","journal-title":"Biochem J"}],"container-title":["Journal of Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391912002473?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391912002473?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T01:49:01Z","timestamp":1713923341000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1874391912002473"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":29,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["S1874391912002473"],"URL":"https:\/\/doi.org\/10.1016\/j.jprot.2012.04.028","relation":{},"ISSN":["1874-3919"],"issn-type":[{"value":"1874-3919","type":"print"}],"subject":[],"published":{"date-parts":[[2012,6]]}}}