{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T04:08:38Z","timestamp":1774066118735,"version":"3.50.1"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"CAPES","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"publisher","award":["441878\/2014-8"],"award-info":[{"award-number":["441878\/2014-8"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"publisher","award":["309596\/2013-0"],"award-info":[{"award-number":["309596\/2013-0"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"FAPESP","doi-asserted-by":"publisher","award":["2014\/06863-3"],"award-info":[{"award-number":["2014\/06863-3"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004809","name":"Finep","doi-asserted-by":"publisher","award":["1355\/10"],"award-info":[{"award-number":["1355\/10"]}],"id":[{"id":"10.13039\/501100004809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Proteomics"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.jprot.2016.06.011","type":"journal-article","created":{"date-parts":[[2016,6,24]],"date-time":"2016-06-24T09:45:51Z","timestamp":1466761551000},"page":"12-23","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["7-Ketocholesterol overcomes drug resistance in chronic myeloid leukemia cell lines beyond MDR1 mechanism"],"prefix":"10.1016","volume":"151","author":[{"given":"L\u00edvia","family":"Rosa Fernandes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Carolina Bassi","family":"Stern","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita de C\u00e1ssia","family":"Cavaglieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F\u00e1bio C\u00e9sar Sousa","family":"Nogueira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilberto","family":"Domont","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1336-6151","authenticated-orcid":false,"given":"Giuseppe","family":"Palmisano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e9rgio Paulo","family":"Bydlowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jprot.2016.06.011_bb0005","first-page":"8","article-title":"Chronic myeloid leukaemia in the 21st century","volume":"76","author":"Frazer","year":"2007","journal-title":"Ulster Med. J."},{"issue":"5405","key":"10.1016\/j.jprot.2016.06.011_bb0010","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/243290a0","article-title":"Letter: a new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining","volume":"243","author":"Rowley","year":"1973","journal-title":"Nature"},{"issue":"23","key":"10.1016\/j.jprot.2016.06.011_bb0015","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1056\/NEJMoa062867","article-title":"Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia","volume":"355","author":"Druker","year":"2006","journal-title":"N. Engl. J. Med."},{"issue":"19","key":"10.1016\/j.jprot.2016.06.011_bb0020","doi-asserted-by":"crossref","first-page":"8912","DOI":"10.1158\/0008-5472.CAN-05-0076","article-title":"Bcr-Abl expression levels determine the rate of development of resistance to imatinib mesylate in chronic myeloid leukemia","volume":"65","author":"Barnes","year":"2005","journal-title":"Cancer Res."},{"key":"10.1016\/j.jprot.2016.06.011_bb0025","article-title":"The biology of CML blast crisis, hematology\/the education program of the American Society of Hematology","volume":"384\u201391","author":"Radich","year":"2007","journal-title":"Am. Soc. Hematol. Educ. Prog."},{"issue":"3","key":"10.1016\/j.jprot.2016.06.011_bb0030","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1182\/blood.V96.3.1070","article-title":"Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: diverse mechanisms of resistance","volume":"96","author":"Mahon","year":"2000","journal-title":"Blood"},{"issue":"5","key":"10.1016\/j.jprot.2016.06.011_bb0035","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/j.1600-0609.2011.01689.x","article-title":"Recent developments in drug resistance mechanism in chronic myeloid leukemia: a review","volume":"87","author":"Vaidya","year":"2011","journal-title":"Eur. J. Haematol."},{"issue":"4","key":"10.1016\/j.jprot.2016.06.011_bb0040","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1038\/leu.2010.16","article-title":"Chronic myeloid leukemia CD34+ cells have reduced uptake of imatinib due to low OCT-1 activity","volume":"24","author":"Engler","year":"2010","journal-title":"Leukemia"},{"key":"10.1016\/j.jprot.2016.06.011_bb0045","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1146\/annurev.med.53.082901.103929","article-title":"Mechanisms of cancer drug resistance","volume":"53","author":"Gottesman","year":"2002","journal-title":"Annu. Rev. Med."},{"issue":"4","key":"10.1016\/j.jprot.2016.06.011_bb0050","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.bbrc.2015.01.045","article-title":"ABCB1, ABCC1, and LRP gene expressions are altered by LDL, HDL, and serum deprivation in a human doxorubicin-resistant uterine sarcoma cell line","volume":"457","author":"Celestino","year":"2015","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"1","key":"10.1016\/j.jprot.2016.06.011_bb0055","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.ejps.2005.08.007","article-title":"Drug permeability across a phospholipid vesicle based barrier: a novel approach for studying passive diffusion","volume":"27","author":"Flaten","year":"2006","journal-title":"Eur. J. Pharm. Sci."},{"issue":"3","key":"10.1016\/j.jprot.2016.06.011_bb0060","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/nrd2438","article-title":"Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?","volume":"7","author":"Dobson","year":"2008","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.jprot.2016.06.011_bb0065","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0076-6879(05)01019-0","article-title":"Glutathione S-transferases as regulators of kinase pathways and anticancer drug targets","volume":"401","author":"Townsend","year":"2005","journal-title":"Methods Enzymol."},{"issue":"1","key":"10.1016\/j.jprot.2016.06.011_bb0070","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/toxsci\/kfj061","article-title":"Human sulfotransferases and their role in chemical metabolism","volume":"90","author":"Gamage","year":"2006","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.jprot.2016.06.011_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2013.02.033","article-title":"Interrelationship between ATP-binding cassette transporters and oxysterols","author":"Ruiz","year":"2013","journal-title":"Biochem. Pharmacol."},{"issue":"1","key":"10.1016\/j.jprot.2016.06.011_bb0080","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1002\/jcp.1040830114","article-title":"Reduced permeability in CHO cells as a mechanism of resistance to colchicine","volume":"83","author":"Ling","year":"1974","journal-title":"J. Cell. Physiol."},{"issue":"20","key":"10.1016\/j.jprot.2016.06.011_bb0085","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1093\/jnci\/djq364","article-title":"Therapy-induced senescence in cancer","volume":"102","author":"Ewald","year":"2010","journal-title":"J. Natl. Cancer Inst."},{"issue":"2\u20134","key":"10.1016\/j.jprot.2016.06.011_bb0090","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0009-3084(87)90046-6","article-title":"Cholesterol autoxidation 1981\u20131986","volume":"44","author":"Smith","year":"1987","journal-title":"Chem. Phys. Lipids"},{"key":"10.1016\/j.jprot.2016.06.011_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2013.02.029","article-title":"Oxysterols in cancer cell proliferation and death","author":"de Weille","year":"2013","journal-title":"Biochem. Pharmacol."},{"issue":"1","key":"10.1016\/j.jprot.2016.06.011_bb0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0021-9150(98)00196-8","article-title":"Oxysterols and atherosclerosis","volume":"142","author":"Brown","year":"1999","journal-title":"Atherosclerosis"},{"issue":"5","key":"10.1016\/j.jprot.2016.06.011_bb0105","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1161\/01.ATV.0000013312.32196.49","article-title":"Oxysterols: friends, foes, or just fellow passengers?","volume":"22","author":"Bjorkhem","year":"2002","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"5","key":"10.1016\/j.jprot.2016.06.011_bb0110","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1097\/MOL.0b013e328356dba0","article-title":"Macrophage oxysterols and their binding proteins: roles in atherosclerosis","volume":"23","author":"Olkkonen","year":"2012","journal-title":"Curr. Opin. Lipidol."},{"issue":"5","key":"10.1016\/j.jprot.2016.06.011_bb0115","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1080\/07853890701379767","article-title":"Cytochrome P450\u2014physiological key factor against cholesterol accumulation and the atherosclerotic vascular process","volume":"39","author":"Luoma","year":"2007","journal-title":"Ann. Med."},{"issue":"4","key":"10.1016\/j.jprot.2016.06.011_bb0120","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.bbrc.2011.05.071","article-title":"Lipid accumulation and lysosomal pathways contribute to dysfunction and apoptosis of human endothelial cells caused by 7-oxysterols","volume":"409","author":"Li","year":"2011","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.jprot.2016.06.011_bb0125","doi-asserted-by":"crossref","first-page":"439","DOI":"10.4067\/S0716-97602010000400008","article-title":"Synthetic nanoemulsion resembling a protein-free model of 7-ketocholesterol containing low density lipoprotein: in vitro and in vivo studies","volume":"43","author":"Favero","year":"2010","journal-title":"Biol. Res."},{"issue":"5","key":"10.1016\/j.jprot.2016.06.011_bb0130","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/jbt.20096","article-title":"Activation of caspase-3-dependent and -independent pathways during 7-ketocholesterol- and 7beta-hydroxycholesterol-induced cell death: a morphological and biochemical study","volume":"19","author":"Prunet","year":"2005","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.jprot.2016.06.011_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2014.01.132","article-title":"Short-term effects of 7-ketocholesterol on human adipose tissue mesenchymal stem cells in vitro","author":"Levy","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.jprot.2016.06.011_bb0140","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/S0006-291X(03)00412-1","article-title":"Impairment of the cytotoxic and oxidative activities of 7 beta-hydroxycholesterol and 7-ketocholesterol by esterification with oleate","volume":"303","author":"Monier","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jprot.2016.06.011_bb0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.steroids.2015.02.003","article-title":"Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7beta-hydroxycholesterol-, or 24(S)-hydroxycholesterol: protective effects of alpha-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3)","author":"Nury","year":"2015","journal-title":"Steroids"},{"issue":"4","key":"10.1016\/j.jprot.2016.06.011_bb0150","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/j.reprotox.2006.05.006","article-title":"Induction of apoptosis by 25-hydroxycholesterol in adult rat Leydig cells: protective effect of 17beta-estradiol","volume":"22","author":"Travert","year":"2006","journal-title":"Reprod. Toxicol."},{"issue":"1","key":"10.1016\/j.jprot.2016.06.011_bb0155","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1590\/S0001-37652001000100007","article-title":"Multidrug resistance in tumour cells: characterization of the multidrug resistant cell line K562-Lucena 1","volume":"73","author":"Rumjanek","year":"2001","journal-title":"An. Acad. Bras. Cienc."},{"issue":"48","key":"10.1016\/j.jprot.2016.06.011_bb0160","doi-asserted-by":"crossref","first-page":"6314","DOI":"10.1038\/onc.2010.375","article-title":"Hedgehog signaling maintains chemoresistance in myeloid leukemic cells","volume":"29","author":"Queiroz","year":"2010","journal-title":"Oncogene"},{"issue":"11","key":"10.1016\/j.jprot.2016.06.011_bb0165","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1074\/mcp.M112.017509","article-title":"A novel method for the simultaneous enrichment, identification, and quantification of phosphopeptides and sialylated glycopeptides applied to a temporal profile of mouse brain development","volume":"11","author":"Palmisano","year":"2012","journal-title":"Mol. Cell. Proteomics"},{"issue":"17","key":"10.1016\/j.jprot.2016.06.011_bb0170","doi-asserted-by":"crossref","first-page":"2704","DOI":"10.1002\/pmic.201200039","article-title":"Global proteome changes in larvae of Callosobruchus maculatus (Coleoptera:Chrysomelidae:Bruchinae) following ingestion of a cysteine proteinase inhibitor","volume":"12","author":"Nogueira","year":"2012","journal-title":"Proteomics"},{"issue":"1\u20132","key":"10.1016\/j.jprot.2016.06.011_bb0175","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s11010-013-1761-0","article-title":"Characterization of a multidrug-resistant chronic myeloid leukemia cell line presenting multiple resistance mechanisms","volume":"383","author":"Daflon-Yunes","year":"2013","journal-title":"Mol. Cell. Biochem."},{"issue":"1","key":"10.1016\/j.jprot.2016.06.011_bb0180","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.bcp.2013.02.029","article-title":"Oxysterols in cancer cell proliferation and death","volume":"86","author":"de Weille","year":"2013","journal-title":"Biochem. Pharmacol."},{"issue":"2","key":"10.1016\/j.jprot.2016.06.011_bb0185","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.ajpath.2013.04.028","article-title":"7-Ketocholesterol induces autophagy in vascular smooth muscle cells through Nox4 and Atg4B","volume":"183","author":"He","year":"2013","journal-title":"Am. J. Pathol."},{"issue":"3","key":"10.1016\/j.jprot.2016.06.011_bb0190","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.bbrc.2013.11.081","article-title":"Induction of oxiapoptophagy, a mixed mode of cell death associated with oxidative stress, apoptosis and autophagy, on 7-ketocholesterol-treated 158N murine oligodendrocytes: impairment by alpha-tocopherol","volume":"446","author":"Nury","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"5","key":"10.1016\/j.jprot.2016.06.011_bb0195","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1161\/01.ATV.19.5.1190","article-title":"Characterization and comparison of the mode of cell death, apoptosis versus necrosis, induced by 7beta-hydroxycholesterol and 7-ketocholesterol in the cells of the vascular wall","volume":"19","author":"Lizard","year":"1999","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"5381","key":"10.1016\/j.jprot.2016.06.011_bb0200","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1126\/science.281.5381.1309","article-title":"Mitochondria and apoptosis","volume":"281","author":"Green","year":"1998","journal-title":"Science"},{"issue":"9","key":"10.1016\/j.jprot.2016.06.011_bb0205","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/nrm2952","article-title":"Mitochondria and cell death: outer membrane permeabilization and beyond","volume":"11","author":"Tait","year":"2010","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"16","key":"10.1016\/j.jprot.2016.06.011_bb0210","doi-asserted-by":"crossref","first-page":"2850","DOI":"10.1038\/sj.onc.1207534","article-title":"Role of mitochondrial membrane permeabilization in apoptosis and cancer","volume":"23","author":"Henry-Mowatt","year":"2004","journal-title":"Oncogene"},{"issue":"2","key":"10.1016\/j.jprot.2016.06.011_bb0215","doi-asserted-by":"crossref","first-page":"149","DOI":"10.32604\/biocell.2005.29.149","article-title":"Mitochondrial apoptotic pathways","volume":"29","author":"Mohamad","year":"2005","journal-title":"Biocell"},{"issue":"13","key":"10.1016\/j.jprot.2016.06.011_bb0220","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1096\/fasebj.9.13.7557017","article-title":"The biochemistry of programmed cell death","volume":"9","author":"Kroemer","year":"1995","journal-title":"FASEB J."},{"issue":"2","key":"10.1016\/j.jprot.2016.06.011_bb0225","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/S0003-9861(02)00085-1","article-title":"7-Ketocholesterol and staurosporine induce opposite changes in intracellular pH, associated with distinct types of cell death in ECV304 cells","volume":"402","author":"Ghelli","year":"2002","journal-title":"Arch. Biochem. Biophys."},{"issue":"12","key":"10.1016\/j.jprot.2016.06.011_bb0230","doi-asserted-by":"crossref","first-page":"5569","DOI":"10.1167\/iovs.06-0333","article-title":"Activation of caspase-8 and caspase-12 pathways by 7-ketocholesterol in human retinal pigment epithelial cells","volume":"47","author":"Luthra","year":"2006","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"3","key":"10.1016\/j.jprot.2016.06.011_bb0235","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0006-2952(02)01110-3","article-title":"Analysis of oxidative processes and of myelin figures formation before and after the loss of mitochondrial transmembrane potential during 7beta-hydroxycholesterol and 7-ketocholesterol-induced apoptosis: comparison with various pro-apoptotic chemicals","volume":"64","author":"Miguet-Alfonsi","year":"2002","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.jprot.2016.06.011_bb0240","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1477-5956-10-23","article-title":"A comparative proteomic study identified LRPPRC and MCM7 as putative actors in imatinib mesylate cross-resistance in Lucena cell line","volume":"10","author":"Correa","year":"2012","journal-title":"Proteome Sci."},{"issue":"4","key":"10.1016\/j.jprot.2016.06.011_bb0245","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1038\/labinvest.3780063","article-title":"AAC-11 overexpression induces invasion and protects cervical cancer cells from apoptosis","volume":"80","author":"Kim","year":"2000","journal-title":"Lab. Investig."},{"issue":"1","key":"10.1016\/j.jprot.2016.06.011_bb0250","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0169-5002(01)00213-6","article-title":"Expression of the antiapoptosis gene, AAC-11, as a prognosis marker in non-small cell lung cancer","volume":"34","author":"Sasaki","year":"2001","journal-title":"Lung Cancer"},{"issue":"6","key":"10.1016\/j.jprot.2016.06.011_bb0255","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1189\/jlb.0607425","article-title":"The antiapoptotic protein Api5 and its partner, high molecular weight FGF2, are up-regulated in B cell chronic lymphoid leukemia","volume":"82","author":"Krejci","year":"2007","journal-title":"J. Leukoc. Biol."},{"issue":"11","key":"10.1016\/j.jprot.2016.06.011_bb0260","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.0020196","article-title":"Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo","volume":"2","author":"Morris","year":"2006","journal-title":"PLoS Genet."},{"issue":"8","key":"10.1016\/j.jprot.2016.06.011_bb0265","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0071443","article-title":"Api5 contributes to E2F1 control of the G1\/S cell cycle phase transition","volume":"8","author":"Garcia-Jove Navarro","year":"2013","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.jprot.2016.06.011_bb0270","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1038\/emboj.2009.106","article-title":"The antiapoptotic protein AAC-11 interacts with and regulates Acinus-mediated DNA fragmentation","volume":"28","author":"Rigou","year":"2009","journal-title":"EMBO J."},{"issue":"10","key":"10.1016\/j.jprot.2016.06.011_bb0275","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1016\/j.febslet.2008.03.057","article-title":"Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest","volume":"582","author":"Sun","year":"2008","journal-title":"FEBS Lett."},{"issue":"6","key":"10.1016\/j.jprot.2016.06.011_bb0280","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.3892\/ijo.2014.2349","article-title":"microRNA-504 inhibits cancer cell proliferation via targeting CDK6 in hypopharyngeal squamous cell carcinoma","volume":"44","author":"Kikkawa","year":"2014","journal-title":"Int. J. Oncol."},{"issue":"15","key":"10.1016\/j.jprot.2016.06.011_bb0285","doi-asserted-by":"crossref","first-page":"4065","DOI":"10.1182\/blood-2010-07-299644","article-title":"c-JUN promotes BCR-ABL-induced lymphoid leukemia by inhibiting methylation of the 5\u2032 region of Cdk6","volume":"117","author":"Kollmann","year":"2011","journal-title":"Blood"},{"issue":"8","key":"10.1016\/j.jprot.2016.06.011_bb0290","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/j.leukres.2014.06.001","article-title":"Changes in gene expression profile in two multidrug resistant cell lines derived from a same drug sensitive cell line","volume":"38","author":"Moreira","year":"2014","journal-title":"Leuk. Res."},{"issue":"1","key":"10.1016\/j.jprot.2016.06.011_bb0295","first-page":"93","article-title":"Ultrastructural features and P-glycoprotein immunolocalization in Saos-2\/DX580 multidrug-resistant human osteosarcoma cells","volume":"28","author":"Maraldi","year":"1996","journal-title":"J. Submicrosc. Cytol. Pathol."},{"issue":"1","key":"10.1016\/j.jprot.2016.06.011_bb0300","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1768-322X.1999.tb01080.x","article-title":"P-glycoprotein subcellular localization and cell morphotype in MDR1 gene-transfected human osteosarcoma cells","volume":"91","author":"Maraldi","year":"1999","journal-title":"Biol. Cell."},{"key":"10.1016\/j.jprot.2016.06.011_bb0305","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1479-7364-6-6","article-title":"The human protein disulfide isomerase gene family","volume":"6","author":"Galligan","year":"2012","journal-title":"Hum. Genomics"},{"key":"10.1016\/j.jprot.2016.06.011_bb0310","article-title":"Pro-apoptotic activities of PDI and PDIA3: a role of Bcl-2 protein Bak","author":"Zhao","year":"2015","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.jprot.2016.06.011_bb0315","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.jnutbio.2008.10.002","article-title":"Lycopene prevents 7-ketocholesterol-induced oxidative stress, cell cycle arrest and apoptosis in human macrophages","volume":"21","author":"Palozza","year":"2010","journal-title":"J. Nutr. Biochem."},{"issue":"24","key":"10.1016\/j.jprot.2016.06.011_bb0320","doi-asserted-by":"crossref","first-page":"10703","DOI":"10.1128\/MCB.24.24.10703-10717.2004","article-title":"NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle cells","volume":"24","author":"Pedruzzi","year":"2004","journal-title":"Mol. Cell. Biol."},{"issue":"3","key":"10.1016\/j.jprot.2016.06.011_bb0325","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1161\/CIRCRESAHA.108.183749","article-title":"Oxidized low-density lipoproteins trigger endoplasmic reticulum stress in vascular cells: prevention by oxygen-regulated protein 150 expression","volume":"104","author":"Sanson","year":"2009","journal-title":"Circ. Res."},{"issue":"3","key":"10.1016\/j.jprot.2016.06.011_bb0330","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1006\/gyno.2002.6654","article-title":"Uptake of a cholesterol-rich emulsion by breast cancer","volume":"85","author":"Graziani","year":"2002","journal-title":"Gynecol. Oncol."}],"container-title":["Journal of Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391916302500?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391916302500?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T21:24:28Z","timestamp":1600809868000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1874391916302500"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":66,"alternative-id":["S1874391916302500"],"URL":"https:\/\/doi.org\/10.1016\/j.jprot.2016.06.011","relation":{},"ISSN":["1874-3919"],"issn-type":[{"value":"1874-3919","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"7-Ketocholesterol overcomes drug resistance in chronic myeloid leukemia cell lines beyond MDR1 mechanism","name":"articletitle","label":"Article Title"},{"value":"Journal of Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jprot.2016.06.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}