{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T14:22:16Z","timestamp":1769610136177,"version":"3.49.0"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100005046","name":"Natural Science Foundation of Heilongjiang Province","doi-asserted-by":"publisher","award":["C2016067"],"award-info":[{"award-number":["C2016067"]}],"id":[{"id":"10.13039\/501100005046","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Harbin Science and Technology innovative talents","award":["2015RQQYJ073"],"award-info":[{"award-number":["2015RQQYJ073"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31302091"],"award-info":[{"award-number":["31302091"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31672575"],"award-info":[{"award-number":["31672575"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010042","name":"Special Fund for Agro-scientific Research in the Public Interest","doi-asserted-by":"crossref","award":["201303034"],"award-info":[{"award-number":["201303034"]}],"id":[{"id":"10.13039\/501100010042","id-type":"DOI","asserted-by":"crossref"}]},{"name":"State's Key Project of Research and Development Plan","award":["2016YFD0500700"],"award-info":[{"award-number":["2016YFD0500700"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Proteomics"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1016\/j.jprot.2017.05.014","type":"journal-article","created":{"date-parts":[[2017,5,17]],"date-time":"2017-05-17T13:46:53Z","timestamp":1495028813000},"page":"111-117","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Identification of novel Haemophilus parasuis serovar 5 vaccine candidates using an immunoproteomic approach"],"prefix":"10.1016","volume":"163","author":[{"given":"Gang","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianjun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dapeng","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanhe","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul R.","family":"Langford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanwen","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siguo","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunlai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jprot.2017.05.014_bb0005","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.rvsc.2008.07.010","article-title":"Blood cellular immune response in pigs immunized and challenged with Haemophilus parasuis","volume":"86","author":"de la Fuente","year":"2009","journal-title":"Res. Vet. Sci."},{"issue":"38","key":"10.1016\/j.jprot.2017.05.014_bb0010","doi-asserted-by":"crossref","first-page":"5271","DOI":"10.1016\/j.vaccine.2009.06.051","article-title":"Identification and characterization of novel immunogenic outer membrane proteins of Haemophilus parasuis serovar 5","volume":"27","author":"Zhou","year":"2009","journal-title":"Vaccine"},{"issue":"1","key":"10.1016\/j.jprot.2017.05.014_bb0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.vetmic.2003.12.001","article-title":"Haemophilus parasuis: new trends on diagnosis, epidemiology and control","volume":"99","author":"Oliveira","year":"2004","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.jprot.2017.05.014_bb0020","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/s13567-015-0263-3","article-title":"Haemophilus parasuis: infection, immunity and enrofloxacin","volume":"46","author":"Macedo","year":"2015","journal-title":"Vet. Res."},{"key":"10.1016\/j.jprot.2017.05.014_bb0025","doi-asserted-by":"crossref","first-page":"649878","DOI":"10.1155\/2015\/649878","article-title":"Protective efficacy of an inactive vaccine based on the LY02 isolate against acute Haemophilus parasuis infection in piglets","volume":"2015","author":"Li","year":"2015","journal-title":"Biomed. Res. Int."},{"issue":"17","key":"10.1016\/j.jprot.2017.05.014_bb0030","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1136\/vr.151.17.502","article-title":"Protection of vaccinated pigs against experimental infections with homologous and heterologous Haemophilus parasuis","volume":"151","author":"Bak","year":"2002","journal-title":"Vet. Rec."},{"issue":"5","key":"10.1016\/j.jprot.2017.05.014_bb0035","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1292\/jvms.63.487","article-title":"A cross-protection experiment in pigs vaccinated with Haemophilus parasuis serovars 2 and 5 bacterins, and evaluation of a bivalent vaccine under laboratory and field conditions","volume":"63","author":"Takahashi","year":"2001","journal-title":"J. Vet. Med. Sci."},{"issue":"1","key":"10.1016\/j.jprot.2017.05.014_bb0040","first-page":"37","article-title":"Cross protection among Haemophilus parasuis strains in immunized gnotobiotic pigs","volume":"55","author":"Miniats","year":"1991","journal-title":"Can. J. Vet. Res."},{"issue":"3","key":"10.1016\/j.jprot.2017.05.014_bb0045","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.tvjl.2013.08.027","article-title":"Advances in the quest for virulence factors of Haemophilus parasuis","volume":"198","author":"Costa-Hurtado","year":"2013","journal-title":"Vet. J."},{"issue":"3","key":"10.1016\/j.jprot.2017.05.014_bb0050","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/j.1751-0813.2000.tb10586.x","article-title":"Establishment, validation and use of the Kielstein-Rapp-Gabrielson serotyping scheme for Haemophilus parasuis","volume":"78","author":"Rafiee","year":"2000","journal-title":"Aust. Vet. J."},{"issue":"12","key":"10.1016\/j.jprot.2017.05.014_bb0055","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1111\/j.1751-0813.2000.tb10507.x","article-title":"Application of ERIC-PCR for the comparison of isolates of Haemophilus parasuis","volume":"78","author":"Rafiee","year":"2000","journal-title":"Aust. Vet. J."},{"issue":"2","key":"10.1016\/j.jprot.2017.05.014_bb0060","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1128\/JCM.41.2.880-882.2003","article-title":"Value of indirect hemagglutination and coagglutination tests for serotyping Haemophilus parasuis","volume":"41","author":"Del Rio","year":"2003","journal-title":"J. Clin. Microbiol."},{"issue":"3\u20134","key":"10.1016\/j.jprot.2017.05.014_bb0065","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.vetimm.2012.11.014","article-title":"Immunoproteomic analysis of the protective response obtained with subunit and commercial vaccines against Glasser's disease in pigs","volume":"151","author":"Martinez-Martinez","year":"2013","journal-title":"Vet. Immunol. Immunopathol."},{"issue":"6","key":"10.1016\/j.jprot.2017.05.014_bb0070","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1292\/jvms.59.451","article-title":"Effects on endotoxin pathogenicity in pigs with acute septicemia of Haemophilus parasuis infection","volume":"59","author":"Amano","year":"1997","journal-title":"J. Vet. Med. Sci."},{"issue":"2","key":"10.1016\/j.jprot.2017.05.014_bb0075","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1128\/JB.00703-08","article-title":"Trimeric autotransporters of Haemophilus parasuis: generation of an extensive passenger domain repertoire specific for pathogenic strains","volume":"191","author":"Pina","year":"2009","journal-title":"J. Bacteriol."},{"issue":"5","key":"10.1016\/j.jprot.2017.05.014_bb0080","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1128\/JCM.39.5.1757-1762.2001","article-title":"Outer membrane proteins and DNA profiles in strains of Haemophilus parasuis recovered from systemic and respiratory sites","volume":"39","author":"Ruiz","year":"2001","journal-title":"J. Clin. Microbiol."},{"issue":"1\u20132","key":"10.1016\/j.jprot.2017.05.014_bb0085","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.vetmic.2011.12.002","article-title":"Cytolethal distending toxin (CDT) of the Haemophilus parasuis SC096 strain contributes to serum resistance and adherence to and invasion of PK-15 and PUVEC cells","volume":"157","author":"Zhang","year":"2012","journal-title":"Vet. Microbiol."},{"issue":"1","key":"10.1016\/j.jprot.2017.05.014_bb0090","doi-asserted-by":"crossref","first-page":"61","DOI":"10.4056\/sigs.2245029","article-title":"Genome sequence of Haemophilus parasuis strain 29755","volume":"5","author":"Mullins","year":"2011","journal-title":"Stand. Genomic Sci."},{"issue":"4","key":"10.1016\/j.jprot.2017.05.014_bb0095","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1128\/JB.01682-08","article-title":"Complete genome sequence of Haemophilus parasuis SH0165","volume":"191","author":"Yue","year":"2009","journal-title":"J. Bacteriol."},{"issue":"1","key":"10.1016\/j.jprot.2017.05.014_bb0100","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s12223-014-0343-1","article-title":"Fifteen novel immunoreactive proteins of Chinese virulent Haemophilus parasuis serotype 5 verified by an immunoproteomic assay","volume":"60","author":"Yu","year":"2015","journal-title":"Folia Microbiol."},{"issue":"2","key":"10.1016\/j.jprot.2017.05.014_bb0105","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.vaccine.2012.11.003","article-title":"Immunogenicity and protective efficacy of recombinant Haemophilus parasuis SH0165 putative outer membrane proteins","volume":"31","author":"Fu","year":"2013","journal-title":"Vaccine"},{"issue":"14","key":"10.1016\/j.jprot.2017.05.014_bb0110","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1016\/j.vaccine.2015.02.023","article-title":"Identification of secreted proteins as novel antigenic vaccine candidates of Haemophilus parasuis serovar 5","volume":"33","author":"Li","year":"2015","journal-title":"Vaccine"},{"issue":"1","key":"10.1016\/j.jprot.2017.05.014_bb0115","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.vetmic.2010.07.023","article-title":"Identification of novel immunogenic proteins in pathogenic Haemophilus parasuis based on genome sequence analysis","volume":"148","author":"Hong","year":"2011","journal-title":"Vet. Microbiol."},{"issue":"10","key":"10.1016\/j.jprot.2017.05.014_bb0120","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1016\/j.vaccine.2017.01.067","article-title":"Omp16-based vaccine encapsulated by alginate-chitosan microspheres provides significant protection against Haemophilus parasuis in mice","volume":"35","author":"Zheng","year":"2017","journal-title":"Vaccine"},{"key":"10.1016\/j.jprot.2017.05.014_bb0125","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.rvsc.2016.05.006","article-title":"Immune response to oligopeptide permease a (OppA) protein in pigs naturally and experimentally infected with Haemophilus parasuis","volume":"107","author":"Macedo","year":"2016","journal-title":"Res. Vet. Sci."},{"issue":"3\u20134","key":"10.1016\/j.jprot.2017.05.014_bb0130","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.vetmic.2013.02.022","article-title":"Serum cross-reaction among virulence-associated trimeric autotransporters (VtaA) of Haemophilus parasuis","volume":"164","author":"Olvera","year":"2013","journal-title":"Vet. Microbiol."},{"issue":"6","key":"10.1016\/j.jprot.2017.05.014_bb0135","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1128\/CVI.00676-12","article-title":"Protection of piglets by a Haemophilus parasuis ghost vaccine against homologous challenge","volume":"20","author":"Hu","year":"2013","journal-title":"Clin. Vaccine Immunol."},{"issue":"1","key":"10.1016\/j.jprot.2017.05.014_bb0140","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1007\/s11427-010-4106-1","article-title":"Comparative proteome analysis of alkaliphilic Bacillus sp. N16-5 grown on different carbon sources, science China","volume":"54","author":"Li","year":"2011","journal-title":"Life Sci."},{"issue":"26","key":"10.1016\/j.jprot.2017.05.014_bb0145","doi-asserted-by":"crossref","first-page":"2945","DOI":"10.1016\/S0264-410X(00)00107-9","article-title":"Intramuscular immunization with genetically inactivated (ghosts) Actinobacillus pleuropneumoniae serotype 9 protects pigs against homologous aerosol challenge and prevents carrier state","volume":"18","author":"Hensel","year":"2000","journal-title":"Vaccine"},{"issue":"4","key":"10.1016\/j.jprot.2017.05.014_bb0150","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/j.bbrc.2014.03.049","article-title":"Comparative proteome analysis of the extracellular proteins of two Haemophilus parasuis strains Nagasaki and SW114","volume":"446","author":"Wei","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"10","key":"10.1016\/j.jprot.2017.05.014_bb0155","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1128\/CVI.05223-11","article-title":"Identification of the immunogenic outer membrane protein a antigen of Haemophilus parasuis by a proteomics approach and passive immunization with monoclonal antibodies in mice","volume":"18","author":"Tian","year":"2011","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.jprot.2017.05.014_bb0160","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/1477-5956-12-38","article-title":"Comparative proteomic analysis of the membrane proteins of two Haemophilus parasuis strains to identify proteins that may help in habitat adaptation and pathogenesis","volume":"12","author":"Zhang","year":"2014","journal-title":"Proteome Sci."},{"issue":"14","key":"10.1016\/j.jprot.2017.05.014_bb0165","doi-asserted-by":"crossref","first-page":"3684","DOI":"10.1002\/pmic.200401218","article-title":"The extracellular and cytoplasmic proteomes of the non-virulent bacillus anthracis strain UM23C1-2","volume":"5","author":"Antelmann","year":"2005","journal-title":"Proteomics"},{"issue":"30","key":"10.1016\/j.jprot.2017.05.014_bb0170","doi-asserted-by":"crossref","first-page":"13270","DOI":"10.1073\/pnas.1005198107","article-title":"Glutathione import in Haemophilus influenzae Rd is primed by the periplasmic heme-binding protein HbpA","volume":"107","author":"Vergauwen","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jprot.2017.05.014_bb0175","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.actatropica.2015.04.009","article-title":"Development of a recombinant OppA-based indirect hemagglutination test for the detection of antibodies against Haemophilus parasuis","volume":"148","author":"Chen","year":"2015","journal-title":"Acta Trop."},{"issue":"18","key":"10.1016\/j.jprot.2017.05.014_bb0180","doi-asserted-by":"crossref","first-page":"6220","DOI":"10.1128\/JB.186.18.6220-6229.2004","article-title":"The hFbpABC transporter from Haemophilus influenzae functions as a binding-protein-dependent ABC transporter with high specificity and affinity for ferric iron","volume":"186","author":"Anderson","year":"2004","journal-title":"J. Bacteriol."},{"issue":"2\u20133","key":"10.1016\/j.jprot.2017.05.014_bb0185","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/S0264-410X(00)00146-8","article-title":"Catalase immunization from Pseudomonas aeruginosa enhances bacterial clearance in the rat lung","volume":"19","author":"Thomas","year":"2000","journal-title":"Vaccine"},{"issue":"17\u201318","key":"10.1016\/j.jprot.2017.05.014_bb0190","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1016\/S0264-410X(02)00104-4","article-title":"Immune responses in mice to intranasal and intracutaneous administration of a DNA vaccine encoding Helicobacter pylori-catalase","volume":"20","author":"Miyashita","year":"2002","journal-title":"Vaccine"},{"issue":"1","key":"10.1016\/j.jprot.2017.05.014_bb0195","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.rvsc.2011.04.020","article-title":"Evaluation of recombinant proteins of Haemophilus parasuis strain SH0165 as vaccine candidates in a mouse model","volume":"93","author":"Yuan","year":"2012","journal-title":"Res. Vet. Sci."}],"container-title":["Journal of Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391917301811?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391917301811?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T18:22:27Z","timestamp":1589739747000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1874391917301811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":39,"alternative-id":["S1874391917301811"],"URL":"https:\/\/doi.org\/10.1016\/j.jprot.2017.05.014","relation":{},"ISSN":["1874-3919"],"issn-type":[{"value":"1874-3919","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of novel Haemophilus parasuis serovar 5 vaccine candidates using an immunoproteomic approach","name":"articletitle","label":"Article Title"},{"value":"Journal of Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jprot.2017.05.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}