{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T01:28:11Z","timestamp":1770514091369,"version":"3.49.0"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100012440","name":"Berrikuntza + Ikerketa + Osasuna Eusko Fundazioa","doi-asserted-by":"publisher","award":["BIO13\/CI\/005"],"award-info":[{"award-number":["BIO13\/CI\/005"]}],"id":[{"id":"10.13039\/501100012440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012440","name":"Berrikuntza + Ikerketa + Osasuna Eusko Fundazioa","doi-asserted-by":"publisher","award":["PEJ-2014-A-61949"],"award-info":[{"award-number":["PEJ-2014-A-61949"]}],"id":[{"id":"10.13039\/501100012440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002924","name":"Federaci\u00f3n Espa\u00f1ola de Enfermedades Raras","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002924","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","award":["SAF2014-59340-R"],"award-info":[{"award-number":["SAF2014-59340-R"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["IEDI-2015-00638"],"award-info":[{"award-number":["IEDI-2015-00638"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007680","name":"Universidad P\u00fablica de Navarra","doi-asserted-by":"publisher","award":["PRB3-ISCIII"],"award-info":[{"award-number":["PRB3-ISCIII"]}],"id":[{"id":"10.13039\/501100007680","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007680","name":"Universidad P\u00fablica de Navarra","doi-asserted-by":"publisher","award":["PT17\/0019\/0009"],"award-info":[{"award-number":["PT17\/0019\/0009"]}],"id":[{"id":"10.13039\/501100007680","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Proteomics"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.jprot.2018.11.020","type":"journal-article","created":{"date-parts":[[2018,11,29]],"date-time":"2018-11-29T13:58:01Z","timestamp":1543499881000},"page":"168-178","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Oncolytic adenovirus Delta-24-RGD induces a widespread glioma proteotype remodeling during autophagy"],"prefix":"10.1016","volume":"194","author":[{"given":"Andrea","family":"Gonz\u00e1lez-Morales","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aintzane","family":"Zabaleta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Garc\u00eda-Moure","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta M.","family":"Alonso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joaqu\u00edn","family":"Fern\u00e1ndez-Irigoyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8046-8102","authenticated-orcid":false,"given":"Enrique","family":"Santamar\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jprot.2018.11.020_bb0005","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1002\/(SICI)1521-1878(199911)21:11<950::AID-BIES7>3.0.CO;2-D","article-title":"Functions of the retinoblastoma protein","volume":"21","author":"Kaelin","year":"1999","journal-title":"BioEssays"},{"key":"10.1016\/j.jprot.2018.11.020_bb0010","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1212\/WNL.51.5.1250","article-title":"The functional role of tumor suppressor genes in gliomas: clues for future therapeutic strategies","volume":"51","author":"Fueyo","year":"1998","journal-title":"Neurology"},{"key":"10.1016\/j.jprot.2018.11.020_bb0015","doi-asserted-by":"crossref","first-page":"3365","DOI":"10.1038\/sj.onc.1202575","article-title":"Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth","volume":"17","author":"Grana","year":"1998","journal-title":"Oncogene"},{"key":"10.1016\/j.jprot.2018.11.020_bb0020","first-page":"425","article-title":"Adenovirus e1a proteins and transformation (review)","volume":"5","author":"Bayley","year":"1994","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.jprot.2018.11.020_bb0025","first-page":"3955","article-title":"Mapping of cellular protein-binding sites on the products of early-region 1A of human adenovirus type 5","volume":"8","author":"Egan","year":"1988","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.jprot.2018.11.020_bb0030","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1038\/sj.onc.1203251","article-title":"A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo","volume":"19","author":"Fueyo","year":"2000","journal-title":"Oncogene"},{"key":"10.1016\/j.jprot.2018.11.020_bb0035","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1093\/jnci\/95.9.652","article-title":"Preclinical characterization of the antiglioma activity of a tropism-enhanced adenovirus targeted to the retinoblastoma pathway","volume":"95","author":"Fueyo","year":"2003","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.jprot.2018.11.020_bb0040","first-page":"120","article-title":"A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency","volume":"7","author":"Suzuki","year":"2001","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.jprot.2018.11.020_bb0045","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1038\/nbt0697-542","article-title":"Alpha v integrins as receptors for tumor targeting by circulating ligands","volume":"15","author":"Pasqualini","year":"1997","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.jprot.2018.11.020_bb0050","article-title":"Delta-24-RGD oncolytic adenovirus elicits anti-glioma immunity in an immunocompetent mouse model","volume":"9","author":"Jiang","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.jprot.2018.11.020_bb0055","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1093\/jnci\/djm102","article-title":"Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: role of autophagic cell death","volume":"99","author":"Jiang","year":"2007","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.jprot.2018.11.020_bb0060","doi-asserted-by":"crossref","first-page":"422","DOI":"10.2174\/156652309789753356","article-title":"Oncolytic adenovirus: preclinical and clinical studies in patients with human malignant gliomas","volume":"9","author":"Jiang","year":"2009","journal-title":"Curr. Gene Ther."},{"issue":"5","key":"10.1016\/j.jprot.2018.11.020_bb0065","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1093\/neuros\/nyx507","article-title":"Phase I trial of DNX-2401 for diffuse intrinsic pontine glioma newly diagnosed in pediatric patients","volume":"83","author":"Tejada","year":"2018","journal-title":"Neurosurgery"},{"key":"10.1016\/j.jprot.2018.11.020_bb0070","doi-asserted-by":"crossref","unstructured":"Lang FF, Conrad C, Gomez-Manzano C, Yung WKA, Sawaya R, Weinberg JS, et al. Phase I study of DNX-2401 (Delta-24-RGD) oncolytic adenovirus: replication and immunotherapeutic effects in recurrent malignant glioma. J. Clin. Oncol.36:1419\u201327.","DOI":"10.1200\/JCO.2017.75.8219"},{"key":"10.1016\/j.jprot.2018.11.020_bb0075","doi-asserted-by":"crossref","first-page":"5295","DOI":"10.1038\/onc.2014.452","article-title":"C-Jun N-terminal kinases are required for oncolytic adenovirus-mediated autophagy","volume":"34","author":"Klein","year":"2015","journal-title":"Oncogene"},{"key":"10.1016\/j.jprot.2018.11.020_bb0080","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1093\/jnci\/djj161","article-title":"Autophagic cell death of malignant glioma cells induced by a conditionally replicating adenovirus","volume":"98","author":"Ito","year":"2006","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.jprot.2018.11.020_bb0085","doi-asserted-by":"crossref","first-page":"118","DOI":"10.4161\/auto.5260","article-title":"Adenovirus's last trick: you say lysis, we say autophagy","volume":"4","author":"Jiang","year":"2008","journal-title":"Autophagy"},{"key":"10.1016\/j.jprot.2018.11.020_bb0090","doi-asserted-by":"crossref","first-page":"4720","DOI":"10.1128\/JVI.02032-10","article-title":"Human adenovirus type 5 induces cell lysis through autophagy and autophagy-triggered caspase activity","volume":"85","author":"Jiang","year":"2011","journal-title":"J. Virol."},{"key":"10.1016\/j.jprot.2018.11.020_bb0095","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0029467","article-title":"The E1B19K oncoprotein complexes with Beclin 1 to regulate autophagy in adenovirus-infected cells","volume":"6","author":"Piya","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jprot.2018.11.020_bb0100","doi-asserted-by":"crossref","unstructured":"Gonzalez-Morales A, Zabaleta A, Guruceaga E, Alonso MM, Garcia-Moure M, Fernandez-Irigoyen J, et al. Spatial and temporal proteome dynamics of glioma cells during oncolytic adenovirus Delta-24-RGD infection. Oncotarget9:31045\u201365.","DOI":"10.18632\/oncotarget.25774"},{"key":"10.1016\/j.jprot.2018.11.020_bb0105","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/nbt.2839","article-title":"ProteomeXchange provides globally coordinated proteomics data submission and dissemination","volume":"32","author":"Vizcaino","year":"2014","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.jprot.2018.11.020_bb0110","doi-asserted-by":"crossref","unstructured":"Szklarczyk D, Morris JH, Cook H, Kuhn M, Wyder S, Simonovic M, et al. The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible. Nucleic Acids Res.45:D362-D8.","DOI":"10.1093\/nar\/gkw937"},{"key":"10.1016\/j.jprot.2018.11.020_bb0115","doi-asserted-by":"crossref","unstructured":"Tyanova S, Temu T, Sinitcyn P, Carlson A, Hein MY, Geiger T, et al. The Perseus computational platform for comprehensive analysis of (prote)omics data. Nat. Methods13:731\u201340.","DOI":"10.1038\/nmeth.3901"},{"key":"10.1016\/j.jprot.2018.11.020_bb0120","doi-asserted-by":"crossref","unstructured":"Moritz CP. Tubulin or not tubulin: heading toward total protein staining as loading control in western blots. Proteomics17.","DOI":"10.1002\/pmic.201600189"},{"key":"10.1016\/j.jprot.2018.11.020_bb0125","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1007\/s00018-017-2483-3","article-title":"On glioblastoma and the search for a cure: where do we stand?","volume":"74","author":"Bianco","year":"2017","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.jprot.2018.11.020_bb0130","doi-asserted-by":"crossref","unstructured":"Lawler SE, Speranza MC, Cho CF, Chiocca EA. Oncolytic viruses in cancer treatment: a review. JAMA Oncol.3:841\u20139.","DOI":"10.1001\/jamaoncol.2016.2064"},{"key":"10.1016\/j.jprot.2018.11.020_bb0135","doi-asserted-by":"crossref","unstructured":"Panek WK, Kane JR, Young JS, Rashidi A, Kim JW, Kanojia D, et al. Hitting the nail on the head: combining oncolytic adenovirus-mediated virotherapy and immunomodulation for the treatment of glioma. Oncotarget8:89391\u2013405.","DOI":"10.18632\/oncotarget.20810"},{"key":"10.1016\/j.jprot.2018.11.020_bb0140","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1042\/bj20031692","article-title":"WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)\/Akt substrate","volume":"378","author":"Vitari","year":"2004","journal-title":"Biochem. J."},{"key":"10.1016\/j.jprot.2018.11.020_bb0145","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1073\/pnas.242728499","article-title":"WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl- -transporting epithelia","volume":"100","author":"Choate","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jprot.2018.11.020_bb0150","doi-asserted-by":"crossref","unstructured":"Zhu W, Begum G, Pointer K, Clark PA, Yang SS, Lin SH, et al. WNK1-OSR1 kinase-mediated phospho-activation of Na+-K+-2Cl- cotransporter facilitates glioma migration. Mol. Cancer13:31.","DOI":"10.1186\/1476-4598-13-31"},{"key":"10.1016\/j.jprot.2018.11.020_bb0155","doi-asserted-by":"crossref","first-page":"11499","DOI":"10.1158\/0008-5472.CAN-07-5312","article-title":"Adenovirus-based strategies overcome temozolomide resistance by silencing the O6-methylguanine-DNA methyltransferase promoter","volume":"67","author":"Alonso","year":"2007","journal-title":"Cancer Res."},{"key":"10.1016\/j.jprot.2018.11.020_bb0160","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1101\/gad.7.11.2135","article-title":"Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain","volume":"7","author":"Hibi","year":"1993","journal-title":"Genes Dev."},{"key":"10.1016\/j.jprot.2018.11.020_bb0165","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/0092-8674(94)90380-8","article-title":"JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain","volume":"76","author":"Derijard","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.jprot.2018.11.020_bb0170","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1158\/0008-5472.CAN-08-3125","article-title":"Cyclin-dependent kinase-3-mediated c-Jun phosphorylation at Ser63 and Ser73 enhances cell transformation","volume":"69","author":"Cho","year":"2009","journal-title":"Cancer Res."},{"key":"10.1016\/j.jprot.2018.11.020_bb0175","doi-asserted-by":"crossref","unstructured":"Blaszczyk K, Nowicka H, Kostyrko K, Antonczyk A, Wesoly J, Bluyssen HA. The unique role of STAT2 in constitutive and IFN-induced transcription and antiviral responses. Cytokine Growth Factor Rev.29:71\u201381.","DOI":"10.1016\/j.cytogfr.2016.02.010"},{"key":"10.1016\/j.jprot.2018.11.020_bb0180","doi-asserted-by":"crossref","first-page":"5814","DOI":"10.1073\/pnas.0402870102","article-title":"Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme","volume":"102","author":"Liang","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jprot.2018.11.020_bb0185","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1146\/annurev-genet-102808-114910","article-title":"Regulation mechanisms and signaling pathways of autophagy","volume":"43","author":"He","year":"2009","journal-title":"Annu. Rev. Genet."},{"key":"10.1016\/j.jprot.2018.11.020_bb0190","doi-asserted-by":"crossref","unstructured":"Tazawa H, Kuroda S, Hasei J, Kagawa S, Fujiwara T. Impact of autophagy in oncolytic adenoviral therapy for cancer. Int. J. Mol. Sci.18.","DOI":"10.3390\/ijms18071479"},{"key":"10.1016\/j.jprot.2018.11.020_bb0195","doi-asserted-by":"crossref","unstructured":"Wick W, Weller M, Weiler M, Batchelor T, Yung AW, Platten M. Pathway inhibition: emerging molecular targets for treating glioblastoma. Neuro-Oncology13:566\u201379.","DOI":"10.1093\/neuonc\/nor039"},{"key":"10.1016\/j.jprot.2018.11.020_bb0200","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1089\/hum.2016.143","article-title":"Functional screening identifies human miRNAs that modulate adenovirus propagation in prostate cancer cells","volume":"28","author":"Hodzic","year":"2017","journal-title":"Hum. Gene Ther."},{"key":"10.1016\/j.jprot.2018.11.020_bb0205","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1038\/sj.gt.3302510","article-title":"Inhibition of NF-kappaB enhances the cytotoxicity of virus-directed enzyme prodrug therapy and oncolytic adenovirus cancer gene therapy","volume":"12","author":"Palmer","year":"2005","journal-title":"Gene Ther."},{"key":"10.1016\/j.jprot.2018.11.020_bb0210","doi-asserted-by":"crossref","first-page":"646","DOI":"10.18632\/oncotarget.322","article-title":"The NFkappaB pathway: a therapeutic target in glioblastoma","volume":"2","author":"Nogueira","year":"2011","journal-title":"Oncotarget"},{"key":"10.1016\/j.jprot.2018.11.020_bb0215","first-page":"237","article-title":"Overexpression of protein kinase C epsilon in astroglial brain tumor derived cell lines and primary tumor samples","volume":"15","author":"Sharif","year":"1999","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.jprot.2018.11.020_bb0220","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1634\/theoncologist.7-1-17","article-title":"Targeting protein kinase C: new therapeutic opportunities against high-grade malignant gliomas?","volume":"7","author":"da Rocha","year":"2002","journal-title":"Oncologist"},{"key":"10.1016\/j.jprot.2018.11.020_bb0225","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/nbt.1513","article-title":"Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy","volume":"27","author":"Du","year":"2009","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.jprot.2018.11.020_bb0230","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1158\/1535-7163.MCT-08-0669","article-title":"Dasatinib-induced autophagy is enhanced in combination with temozolomide in glioma","volume":"8","author":"Milano","year":"2009","journal-title":"Mol. Cancer Ther."},{"key":"10.1016\/j.jprot.2018.11.020_bb0235","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bbrc.2005.03.012","article-title":"Src kinase regulation by phosphorylation and dephosphorylation","volume":"331","author":"Roskoski","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jprot.2018.11.020_bb0240","doi-asserted-by":"crossref","unstructured":"King CR, Cohen MJ, Fonseca GJ, Dirk BS, Dikeakos JD, Mymryk JS. Functional and structural mimicry of cellular protein kinase a anchoring proteins by a viral oncoprotein. PLoS Pathog.12:e1005621.","DOI":"10.1371\/journal.ppat.1005621"},{"key":"10.1016\/j.jprot.2018.11.020_bb0245","doi-asserted-by":"crossref","unstructured":"Majewska E, Szeliga M. AKT\/GSK3beta signaling in glioblastoma. Neurochem. Res.42:918\u201324.","DOI":"10.1007\/s11064-016-2044-4"},{"key":"10.1016\/j.jprot.2018.11.020_bb0250","doi-asserted-by":"crossref","unstructured":"Mucignat-Caretta C, Denaro L, D'Avella D, Caretta A. Protein kinase a distribution differentiates human glioblastoma from brain tissue. Cancers (Basel).10.","DOI":"10.3390\/cancers10010002"},{"key":"10.1016\/j.jprot.2018.11.020_bb0255","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1158\/1078-0432.CCR-08-0760","article-title":"Potential therapeutic effect of glycogen synthase kinase 3beta inhibition against human glioblastoma","volume":"15","author":"Miyashita","year":"2009","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.jprot.2018.11.020_bb0260","doi-asserted-by":"crossref","first-page":"6643","DOI":"10.1158\/0008-5472.CAN-08-0850","article-title":"Glycogen synthase kinase-3 inhibition induces glioma cell death through c-MYC, nuclear factor-kappaB, and glucose regulation","volume":"68","author":"Kotliarova","year":"2008","journal-title":"Cancer Res."},{"key":"10.1016\/j.jprot.2018.11.020_bb0265","doi-asserted-by":"crossref","unstructured":"Ren J, Liu T, Han Y, Wang Q, Chen Y, Li G, et al. GSK-3beta inhibits autophagy and enhances radiosensitivity in non-small cell lung cancer. Diagn. Pathol.13:33.","DOI":"10.1186\/s13000-018-0708-x"},{"key":"10.1016\/j.jprot.2018.11.020_bb0270","doi-asserted-by":"crossref","unstructured":"Dedobbeleer M, Willems E, Freeman S, Lombard A, Goffart N, Rogister B. Phosphatases and solid tumors: focus on glioblastoma initiation, progression and recurrences. Biochem. J.474:2903\u201324.","DOI":"10.1042\/BCJ20170112"},{"key":"10.1016\/j.jprot.2018.11.020_bb0275","doi-asserted-by":"crossref","unstructured":"Mui MZ, Kucharski M, Miron MJ, Hur WS, Berghuis AM, Blanchette P, et al. Identification of the adenovirus E4orf4 protein binding site on the B55alpha and Cdc55 regulatory subunits of PP2A: implications for PP2A function, tumor cell killing and viral replication. PLoS Pathog.9:e1003742.","DOI":"10.1371\/journal.ppat.1003742"},{"key":"10.1016\/j.jprot.2018.11.020_bb0280","doi-asserted-by":"crossref","unstructured":"Mui MZ, Zhou Y, Blanchette P, Chughtai N, Knight JF, Gruosso T, et al. The human adenovirus Type 5 E4orf4 protein targets two phosphatase regulators of the hippo signaling pathway. J. Virol.89:8855\u201370.","DOI":"10.1128\/JVI.03710-14"},{"key":"10.1016\/j.jprot.2018.11.020_bb0285","doi-asserted-by":"crossref","unstructured":"Grallert A, Boke E, Hagting A, Hodgson B, Connolly Y, Griffiths JR, et al. A PP1-PP2A phosphatase relay controls mitotic progression. Nature517:94\u20138.","DOI":"10.1038\/nature14019"},{"key":"10.1016\/j.jprot.2018.11.020_bb0290","doi-asserted-by":"crossref","unstructured":"Kolupaeva V, Janssens V. PP1 and PP2A phosphatases--cooperating partners in modulating retinoblastoma protein activation. FEBS J.280:627\u201343.","DOI":"10.1111\/j.1742-4658.2012.08511.x"},{"key":"10.1016\/j.jprot.2018.11.020_bb0295","doi-asserted-by":"crossref","unstructured":"Zelenay S, Reis E Sousa C. Adaptive immunity after cell death. Trends Immunol.34:329\u201335.","DOI":"10.1016\/j.it.2013.03.005"},{"key":"10.1016\/j.jprot.2018.11.020_bb0300","doi-asserted-by":"crossref","unstructured":"Shibutani ST, Saitoh T, Nowag H, Munz C, Yoshimori T. Autophagy and autophagy-related proteins in the immune system. Nat. Immunol.16:1014\u201324.","DOI":"10.1038\/ni.3273"},{"key":"10.1016\/j.jprot.2018.11.020_bb0305","unstructured":"van den Bossche WBL, Kleijn A, Teunissen CE, Voerman JSA, Teodosio C, Noske DP, et al. Oncolytic virotherapy in glioblastoma patients induces a tumor macrophage phenotypic shift leading to an altered glioblastoma microenvironment. Neuro-Oncology."},{"key":"10.1016\/j.jprot.2018.11.020_bb0310","doi-asserted-by":"crossref","DOI":"10.4161\/21624011.2014.947872","article-title":"Healing after death: antitumor immunity induced by oncolytic adenoviral therapy","volume":"3","author":"Jiang","year":"2014","journal-title":"Oncoimmunology"},{"key":"10.1016\/j.jprot.2018.11.020_bb0315","doi-asserted-by":"crossref","first-page":"3894","DOI":"10.1158\/0008-5472.CAN-17-0468","article-title":"Oncolytic adenovirus and tumor-targeting immune modulatory therapy improve autologous cancer vaccination","volume":"77","author":"Jiang","year":"2017","journal-title":"Cancer Res."},{"key":"10.1016\/j.jprot.2018.11.020_bb0320","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0097495","article-title":"The in vivo therapeutic efficacy of the oncolytic adenovirus Delta24-RGD is mediated by tumor-specific immunity","volume":"9","author":"Kleijn","year":"2014","journal-title":"PLoS One"}],"container-title":["Journal of Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391918304184?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391918304184?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T11:59:22Z","timestamp":1761739162000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1874391918304184"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":64,"alternative-id":["S1874391918304184"],"URL":"https:\/\/doi.org\/10.1016\/j.jprot.2018.11.020","relation":{},"ISSN":["1874-3919"],"issn-type":[{"value":"1874-3919","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oncolytic adenovirus Delta-24-RGD induces a widespread glioma proteotype remodeling during autophagy","name":"articletitle","label":"Article Title"},{"value":"Journal of Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jprot.2018.11.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}