{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T17:06:22Z","timestamp":1775235982560,"version":"3.50.1"},"reference-count":117,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Proteomics"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1016\/j.jprot.2020.103882","type":"journal-article","created":{"date-parts":[[2020,6,27]],"date-time":"2020-06-27T00:48:27Z","timestamp":1593218907000},"page":"103882","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Venomics of the Duvernoy's gland secretion of the false coral snake Rhinobothryum bovallii (Andersson, 1916) and assessment of venom lethality towards synapsid and diapsid animal models"],"prefix":"10.1016","volume":"225","author":[{"given":"Juan J.","family":"Calvete","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabi\u00e1n","family":"Bonilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sof\u00eda","family":"Granados-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Libia","family":"Sanz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Lomonte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmood","family":"Sasa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jprot.2020.103882_bb0005","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1146\/annurev.genom.9.081307.164356","article-title":"The toxicogenomic multiverse: convergent recruitment of proteins into animal venoms","volume":"10","author":"Fry","year":"2009","journal-title":"Annu. Rev. Genomics Hum. Genet."},{"key":"10.1016\/j.jprot.2020.103882_bb0010","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/nature04328","article-title":"Early evolution of the venom system in lizards and snakes","volume":"439","author":"Fry","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.jprot.2020.103882_bb0015","doi-asserted-by":"crossref","DOI":"10.1186\/s12862-015-0358-5","article-title":"The origin of snakes: revealing the ecology, behavior, and evolutionary history of early snakes using genomics, phenomics, and the fossil record","volume":"15","author":"Hsiang","year":"2015","journal-title":"BMC Evol. Biol."},{"key":"10.1016\/j.jprot.2020.103882_bb0020","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/1471-2148-13-93","article-title":"A phylogeny and revised classification of Squamata, including 4161 species of lizards and snakes","volume":"13","author":"Pyron","year":"2013","journal-title":"BMC Evol. Biol."},{"key":"10.1016\/j.jprot.2020.103882_bb0025","doi-asserted-by":"crossref","unstructured":"A. Figueroa, McKelvy, L.L. Grismer, C.D. Bell, S.P. Lailvaux, A Species-level phylogeny of extant snakes with description of a new colubrid subfamily and genus. PLoS One 11 (2016) e0161070. [11] J.P. Chippaux, Snake-bites: appraisal of the global situation. Bull. World Health Organ. 76 (1998) 515\u2013524.","DOI":"10.1371\/journal.pone.0161070"},{"key":"10.1016\/j.jprot.2020.103882_bb0030","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.ympev.2015.10.009","article-title":"Combining phylogenomic and supermatrix approaches, and a time-calibrated phylogeny for squamate reptiles (lizards and snakes) based on 52 genes and 4162 species","volume":"94","author":"Zheng","year":"2016","journal-title":"Mol. Phylogenet. Evol."},{"key":"10.1016\/j.jprot.2020.103882_bb0035","article-title":"Large-scale molecular phylogeny, morphology, divergence-time estimation, and the fossil record of advanced caenophidian snakes (Squamata: Serpentes)","volume":"14","author":"Zaher","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.jprot.2020.103882_bb0040","series-title":"Species 2000 & ITIS Catalogue of Life, 2020-01-10 Beta","article-title":"The Reptile Database version Dec 2015","author":"Uetz","year":"2020"},{"key":"10.1016\/j.jprot.2020.103882_bb0045","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1038\/nature07178","article-title":"Evolutionary origin and development of snake fangs","volume":"454","author":"Vonk","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.jprot.2020.103882_bb0050","article-title":"Snakebite envenoming","volume":"3","author":"Guti\u00e9rrez","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.jprot.2020.103882_bb0055","doi-asserted-by":"crossref","first-page":"e218","DOI":"10.1371\/journal.pmed.0050218","article-title":"The global burden of snakebite a literature analysis and modelling based on regional estimates of envenoming and deaths","volume":"5","author":"Kasturiratne","year":"2008","journal-title":"PLoS Med."},{"key":"10.1016\/j.jprot.2020.103882_bb0060","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0007059","article-title":"Strategy for a globally coordinated response to a priority neglected tropical disease: snakebite envenoming","volume":"13","author":"Williams","year":"2019","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.jprot.2020.103882_bb0065","doi-asserted-by":"crossref","first-page":"185","DOI":"10.3109\/15569543.2014.942040","article-title":"Rear-fanged snake venoms: an untapped source of novel compounds and potential drug leads","volume":"33","author":"Saviola","year":"2014","journal-title":"Toxin Rev."},{"key":"10.1016\/j.jprot.2020.103882_bb0070","first-page":"104","article-title":"Animales ponzonosos de Chile","volume":"20","author":"Schenome","year":"1965","journal-title":"Bol. Chil. Parasitol."},{"key":"10.1016\/j.jprot.2020.103882_bb0075","first-page":"1007","article-title":"Clinical features of twig snake (Thelotornis capensis) envenomation, S","volume":"58","author":"Atkinson","year":"1980","journal-title":"Afr. Med. J."},{"key":"10.1016\/j.jprot.2020.103882_bb0080","first-page":"12","article-title":"Morphologic evidence of toxic saliva in colubrid snakes: a checklist of world genera","volume":"14","author":"McKinstry","year":"1983","journal-title":"Herpet. Rev."},{"key":"10.1016\/j.jprot.2020.103882_bb0085","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1580\/0953-9859-1.2.119","article-title":"Venomous bites by non venomous snakes: a bibliography of colubrid envenomation","volume":"1","author":"Minton","year":"1990","journal-title":"J. Wildl. Med."},{"key":"10.1016\/j.jprot.2020.103882_bb0090","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1081\/TXR-120004744","article-title":"South American colubrid envenomations","volume":"21","author":"Prado-Franceschi","year":"2002","journal-title":"J. Toxicol. Toxin Rev."},{"key":"10.1016\/j.jprot.2020.103882_bb0095","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1081\/TXR-120004746","article-title":"Rhabdophis tigrinus in Japan: pathogenesis of envenomation and production of antivenom","volume":"21","author":"Sawai","year":"2002","journal-title":"J. Toxicol. Toxin Rev."},{"key":"10.1016\/j.jprot.2020.103882_bb0100","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1081\/TXR-120004745","article-title":"Envenomations by colubrid snakes in Africa, Europe, and the Middle East","volume":"21","author":"Kuch","year":"2002","journal-title":"J. Toxicol. Toxin Rev."},{"key":"10.1016\/j.jprot.2020.103882_bb0105","series-title":"Venomous bites from non-venomous snakes: a critical analysis of risk and management of \u201ccolubrid\u201d snake bites","author":"Weinstein","year":"2011"},{"key":"10.1016\/j.jprot.2020.103882_bb0110","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.toxicon.2013.02.003","article-title":"Non-front-fanged colubroid snakes: a current evidence-based analysis of medical significance","volume":"69","author":"Weinstein","year":"2013","journal-title":"Toxicon"},{"key":"10.1016\/j.jprot.2020.103882_bb0115","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1590\/S0037-86822010000300025","article-title":"Poisoning due to Philodryas olfersii (Lichtenstein, 1823) attended at Restaura\u00e7\u00e3o Hospital in Recife, state of Pernambuco, Brazil: case report","volume":"43","author":"Correia","year":"2010","journal-title":"Rev. Soc. Bras. Med. Trop."},{"key":"10.1016\/j.jprot.2020.103882_bb0120","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.toxicon.2014.11.219","article-title":"First reported case of systemic envenoming by the Sri Lankan keelback (Balanophis ceylonensis)","volume":"93","author":"Fernando","year":"2015","journal-title":"Toxicon"},{"key":"10.1016\/j.jprot.2020.103882_bb0125","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.bbagen.2017.01.020","article-title":"What killed Karl Patterson Schmidt? Combined venom gland transcriptomic, venomic and antivenomic analysis of the south African green tree snake (the boomslang), Dispholidus typus","volume":"1861","author":"Pla","year":"2017","journal-title":"Biochim. Biophys. Acta Gen. Subj."},{"key":"10.1016\/j.jprot.2020.103882_bb0130","doi-asserted-by":"crossref","DOI":"10.1186\/s40560-014-0043-6","article-title":"Rhabdophis tigrinus is not a pit viper but its bites result in venom-induced consumptive coagulopathy similar to many viper bites","volume":"2","author":"Silva","year":"2014","journal-title":"J. Intensive Care"},{"key":"10.1016\/j.jprot.2020.103882_bb0135","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1081\/TXR-120004741","article-title":"Biochemistry and pharmacology of colubrid snake venoms","volume":"21","author":"Mackessy","year":"2002","journal-title":"J. Toxicol. Toxin Rev."},{"key":"10.1016\/j.jprot.2020.103882_bb0140","doi-asserted-by":"crossref","first-page":"E230","DOI":"10.3390\/toxins8080230","article-title":"Colubrid venom composition: an -Omics perspective","volume":"8","author":"Junqueira-de-Azevedo","year":"2016","journal-title":"Toxins"},{"issue":"2018","key":"10.1016\/j.jprot.2020.103882_bb0145","article-title":"Adaptive evolution of distinct prey-specific toxin genes in rear-fanged snake venom","volume":"285","author":"Modahl","year":"2018","journal-title":"Proc. R. Soc. B"},{"key":"10.1016\/j.jprot.2020.103882_bb0150","doi-asserted-by":"crossref","first-page":"279","DOI":"10.3389\/fevo.2019.00279","article-title":"Venoms of rear-fanged snakes: new proteins and novel activities","volume":"7","author":"Modahl","year":"2019","journal-title":"Front. Ecol. Evol."},{"key":"10.1016\/j.jprot.2020.103882_bb0155","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1093\/icb\/icw110","article-title":"Understanding biological roles of venoms among the Caenophidia: the importance of rear-fanged snakes","volume":"56","author":"Mackessy","year":"2016","journal-title":"Integr. Comp. Biol."},{"key":"10.1016\/j.jprot.2020.103882_bb0160","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1042\/BIO04106028","article-title":"Snake venomics at the crossroads between ecological and clinical toxinology","volume":"41","author":"Calvete","year":"2019","journal-title":"Biochemist"},{"key":"10.1016\/j.jprot.2020.103882_bb0165","doi-asserted-by":"crossref","first-page":"332","DOI":"10.3389\/fevo.2019.00332","article-title":"Snake venom in context: neglected clades and concepts","volume":"7","author":"Jackson","year":"2019","journal-title":"Front. Ecol. Evol."},{"key":"10.1016\/j.jprot.2020.103882_bb0170","series-title":"Deliciae Florae et Faunae insubricae 3","first-page":"41","author":"Scopoli","year":"1785"},{"key":"10.1016\/j.jprot.2020.103882_bb0175","series-title":"G\u00f6teborgs Kungliga Vetenskap Och Vitter Hets-Samnalles Hndlingar Sjatte Foljden (Series B, 4) 17 (5) [ = Meddelanden Fran G\u00f6teborgs Musei Zoologiska Afdelning, No. 9]","first-page":"1","article-title":"Notes on the reptiles and batrachians in the zoological Museum at Gothenburg with an account of some new species","author":"Andersson","year":"1916"},{"key":"10.1016\/j.jprot.2020.103882_bb0180","first-page":"1","article-title":"As cobras da regi\u00e3o Leste do Par\u00e1","volume":"9","author":"Cunha","year":"1993","journal-title":"Boletim do Museu Paraense Em\u00edlio Goeldi s\u00e9rie Zoologia"},{"key":"10.1016\/j.jprot.2020.103882_bb0185","series-title":"The Amphibians and Reptiles of Costa Rica: A Herpetofauna between Two Continents, between Two Seas","author":"Savage","year":"2002"},{"key":"10.1016\/j.jprot.2020.103882_bb0190","first-page":"199","article-title":"New records of the Amazon banded snake Rhinobothryum lentiginosum (Serpentes: Colubridae) from Mato Grosso state, Brazil, with natural history notes","volume":"51","author":"Gomes de Arruda","year":"2015","journal-title":"Salamandra"},{"key":"10.1016\/j.jprot.2020.103882_bb0195","first-page":"1","article-title":"The reptiles of the upper Amazon basin, Iquitos region, Peru. II. Crocodilians, turtles and snakes. \u2013 contributions in biology and geology","volume":"12","author":"Dixon","year":"1977","journal-title":"Milwaukee Public Museum"},{"key":"10.1016\/j.jprot.2020.103882_bb0200","first-page":"99","article-title":"Rhinobothryum bovallii, Andersson. G\u00e9nero y especie de ofidio nuevos para Venezuela","volume":"2","author":"Pons","year":"1965","journal-title":"Kasmera"},{"key":"10.1016\/j.jprot.2020.103882_bb0205","first-page":"78","article-title":"Natural history of snakes in forests of the Manaus region, Central Amazonia, Brazil","volume":"6","author":"Martins","year":"1998","journal-title":"Herpetological Natural History"},{"key":"10.1016\/j.jprot.2020.103882_bb0210","series-title":"Diversidad de la herpetofauna en la centro Amazon\u00eda de Ecuador","author":"Ortega-Andrade","year":"2010"},{"key":"10.1016\/j.jprot.2020.103882_bb0215","series-title":"The Snakes of Honduras: Systematics, Distribution, and Conservation. Society for the Study of Amphibians and Reptiles, Contributions to Herpetology Volume 26","author":"McCranie","year":"2011"},{"key":"10.1016\/j.jprot.2020.103882_bb0220","first-page":"243","article-title":"On the geographic distribution of the false coral snake, Rhinobothryum bovallii (Serpentes: Dipsadidae), in Colombia \u2013 a biogeographical perspective","volume":"48","author":"Rojas-Morales","year":"2012","journal-title":"Salamandra"},{"key":"10.1016\/j.jprot.2020.103882_bb0225","first-page":"429","article-title":"B. Geographic distribution: Rhinobothryum bovallii (false tree coral)","volume":"47","author":"Flores","year":"2016","journal-title":"Herpetol. Rev."},{"key":"10.1016\/j.jprot.2020.103882_bb0230","first-page":"83","article-title":"Redescubrimiento de las serpientes Rhinobothryum bovallii (Andersson, 1916) y Plesiodipsas perijanensis (Alem\u00e1n, 1953) en Venezuela","volume":"76","author":"Rojas-Runjaic","year":"2018","journal-title":"Mem. Fund. La Salle Ciencias Nat."},{"key":"10.1016\/j.jprot.2020.103882_bb0235","first-page":"138","article-title":"A second locality for Rhinobothryum bovallii Andersson (Colubridae) in nuclear Central America, with comments on its habitat","volume":"5","author":"Turcios-Casco","year":"2018","journal-title":"Mesoamerican Herpetology"},{"key":"10.1016\/j.jprot.2020.103882_bb0240","series-title":"Reptiles of Costa Rica. A Field Guide, Hellbender Publishing, a Zona Tropical Press from Comstock Publishing Associates, an Imprint of","author":"Lenders","year":"2019"},{"key":"10.1016\/j.jprot.2020.103882_bb0245","doi-asserted-by":"crossref","first-page":"555","DOI":"10.15560\/15.4.555","article-title":"First country record of Rhinobothryum bovallii (Anderson, 1916) (Squamata, Colubridae) from Nicaragua","volume":"15","author":"Mart\u00ednez-Fonseca","year":"2019","journal-title":"Check List"},{"key":"10.1016\/j.jprot.2020.103882_bb0250","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.crvi.2009.11.003","article-title":"Dissecting the major American snake radiation: a molecular phylogeny of the Dipsadidae Bonaparte (Serpentes, Caenophidia)","volume":"333","author":"Vidal","year":"2010","journal-title":"Comptes Rendus Biol."},{"key":"10.1016\/j.jprot.2020.103882_bb0255","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.ympev.2010.11.006","article-title":"The phylogeny of advanced snakes (Colubroidea), with discovery of a new subfamily and comparison of support methods for likelihood trees","volume":"58","author":"Pyron","year":"2011","journal-title":"Mol. Phylogenet. Evol."},{"key":"10.1016\/j.jprot.2020.103882_bb0260","series-title":"Four Neotropical Rainforests","first-page":"455","article-title":"Herpetofaunas in Neotropical rainforests: Comparative composition, history, and resource use","author":"Duellman","year":"1990"},{"key":"10.1016\/j.jprot.2020.103882_bb0265","series-title":"La Diversidad Biol\u00f3gica de Iberoam\u00e9rica","first-page":"55","article-title":"Origen y distribuci\u00f3n de la biota suramericana y colombiana","author":"Hern\u00e1ndez-Camacho","year":"1992"},{"key":"10.1016\/j.jprot.2020.103882_bb0270","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1130\/0016-7606(2000)112<1091:UHOTCA>2.0.CO;2","article-title":"Uplift history of the central and northern Andes: a review","volume":"112","author":"Gregory-Wodzicki","year":"2000","journal-title":"Geol. Soc. Am. Bull."},{"key":"10.1016\/j.jprot.2020.103882_bb0275","first-page":"1773","article-title":"Paleogeographic development of South America","volume":"46","author":"Harrington","year":"1962","journal-title":"Bull. Am. Ass. Petroleum Geologist"},{"key":"10.1016\/j.jprot.2020.103882_bb0280","series-title":"The South American Herpetofauna: Its Origin, Evolution and Dispersal","first-page":"217","article-title":"Origin and distribution of reptiles in lowland tropical rainforest of South America","volume":"7","author":"Dixon","year":"1979"},{"key":"10.1016\/j.jprot.2020.103882_bb0285","series-title":"The Reptiles of Central America. \u2013 Herpeton, Offenbach","first-page":"367","author":"K\u00f6hler","year":"2003"},{"key":"10.1016\/j.jprot.2020.103882_bb0290","series-title":"Serpientes de Costa Rica: Distribuci\u00f3n, Taxonomia e Historia Natural\/ Snakes of Costa Rica: Distribution, Taxonomy, and Natural History","author":"Sol\u00f3rzano","year":"2004"},{"key":"10.1016\/j.jprot.2020.103882_bb0295","series-title":"The Amphibians and Reptiles of the Honduran Mosquitia","author":"McCranie","year":"2006"},{"key":"10.1016\/j.jprot.2020.103882_bb0300","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/0041-0101(83)90137-X","article-title":"Preliminary studies on the venom of the colubrid snake Rhabdophis subminatus (red-necked keelback)","volume":"21","author":"Ferlan","year":"1983","journal-title":"Toxicon"},{"key":"10.1016\/j.jprot.2020.103882_bb0305","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool","volume":"215","author":"Altschul","year":"1990","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.jprot.2020.103882_bb0310","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1586\/epr.11.61","article-title":"Proteomic tools against the neglected pathology of snake bite envenoming","volume":"8","author":"Calvete","year":"2011","journal-title":"Expert Rev. Proteomics"},{"key":"10.1016\/j.jprot.2020.103882_bb0315","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1586\/14789450.2014.900447","article-title":"Next-generation snake venomics: protein-locus resolution through venom proteome decomplexation","volume":"11","author":"Calvete","year":"2014","journal-title":"Exp. Rev. Proteomics"},{"key":"10.1016\/j.jprot.2020.103882_bb0320","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1586\/14789450.2015.1073590","article-title":"Constructing comprehensive venom proteome reference maps for integrative venomics","volume":"12","author":"Eichberg","year":"2015","journal-title":"Exp. Rev. Proteomics"},{"key":"10.1016\/j.jprot.2020.103882_bb0325","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jprot.2017.06.001","article-title":"Absolute venomics: absolute quantification of intact venom proteins through elemental mass spectrometry","volume":"164","author":"Calder\u00f3n-Celis","year":"2017","journal-title":"J. Proteomics"},{"key":"10.1016\/j.jprot.2020.103882_bb0330","series-title":"Probit Analysis","article-title":"A statistical treatment of the sigmoid response curve","author":"Finney","year":"1947"},{"key":"10.1016\/j.jprot.2020.103882_bb0335","doi-asserted-by":"crossref","first-page":"E90","DOI":"10.3390\/toxins11020090","article-title":"Vipera berus berus venom from Russia: venomics, bioactivities and preclinical assessment of microgen antivenom","volume":"11","author":"Al-Shekhadat","year":"2019","journal-title":"Toxins"},{"key":"10.1016\/j.jprot.2020.103882_bb0340","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.jprot.2016.02.003","article-title":"Toxicovenomics and antivenom profiling of the eastern green mamba snake (Dendroaspis angusticeps)","volume":"136","author":"Lauridsen","year":"2016","journal-title":"J. Proteomics"},{"key":"10.1016\/j.jprot.2020.103882_bb0345","doi-asserted-by":"crossref","DOI":"10.1186\/s40409-017-0117-8","article-title":"Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms","volume":"23","author":"Lomonte","year":"2017","journal-title":"J. Venom Anim. Toxins Incl. Trop. Dis."},{"key":"10.1016\/j.jprot.2020.103882_bb0350","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.toxicon.2012.02.013","article-title":"The structural and functional diversification of the Toxicofera reptile venom system","volume":"60","author":"Fry","year":"2012","journal-title":"Toxicon"},{"key":"10.1016\/j.jprot.2020.103882_bb0355","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1558-5646.2011.01437.x","article-title":"Extinction ecological opportunity and the origins of global snake diversity","volume":"66","author":"Pyron","year":"2012","journal-title":"Evolution"},{"key":"10.1016\/j.jprot.2020.103882_bb0360","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/BF02338834","article-title":"Evolution of disintegrin cysteine-rich and mammalian matrix-degrading metalloproteinases: gene duplication and divergence of a common ancestor rather than convergent evolution","volume":"43","author":"Moura-da-Silva","year":"1996","journal-title":"J. Mol. Evol."},{"key":"10.1016\/j.jprot.2020.103882_bb0365","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.toxicon.2012.02.006","article-title":"On the ancestral recruitment of metalloproteinases into the venom of snakes","volume":"60","author":"Casewell","year":"2012","journal-title":"Toxicon"},{"key":"10.1016\/j.jprot.2020.103882_bb0370","doi-asserted-by":"crossref","first-page":"E216","DOI":"10.3390\/toxins8070216","article-title":"Insights into the evolution of a snake venom multi-gene family from the genomic organization of Echis ocellatus SVMP genes","volume":"8","author":"Sanz","year":"2016","journal-title":"Toxins"},{"key":"10.1016\/j.jprot.2020.103882_bb0375","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1016\/j.jprot.2011.03.026","article-title":"Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases","volume":"74","author":"Escalante","year":"2011","journal-title":"J. Proteomics"},{"key":"10.1016\/j.jprot.2020.103882_bb0380","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.toxicon.2012.09.004","article-title":"Snake venom metalloproteinases","volume":"62","author":"Markland","year":"2013","journal-title":"Toxicon"},{"key":"10.1016\/j.jprot.2020.103882_bb0385","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3390\/toxins8040093","article-title":"Hemorrhage caused by snake venom metalloproteinases: a journey of discovery and understanding","volume":"8","author":"Guti\u00e9rrez","year":"2016","journal-title":"Toxins"},{"key":"10.1016\/j.jprot.2020.103882_bb0390","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003731","article-title":"Tissue localization and extracellular matrix degradation by PI, PII and PIII snake venom metalloproteinases: clues on the mechanisms of venom-induced hemorrhage","volume":"9","author":"Herrera","year":"2015","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.jprot.2020.103882_bb0395","doi-asserted-by":"crossref","first-page":"63","DOI":"10.3109\/15569549309084186","article-title":"Toxicology and biochemistry of colubridae venoms","volume":"12","author":"Datta","year":"1993","journal-title":"J. Toxicol. Toxin Rev."},{"key":"10.1016\/j.jprot.2020.103882_bb0400","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0003-9861(03)00028-6","article-title":"Wide distribution of cysteine-rich secretory proteins in snake venoms: isolation and cloning of novel snake venom cysteine-rich secretory proteins","volume":"412","author":"Yamazaki","year":"2003","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.jprot.2020.103882_bb0405","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1016\/S0041-0101(00)00091-X","article-title":"Characterization of venom (Duvernoy\u2019s secretion) from twelve species of colubrid snakes and partial sequence of four venom proteins","volume":"38","author":"Hill","year":"2000","journal-title":"Toxicon"},{"key":"10.1016\/j.jprot.2020.103882_bb0410","doi-asserted-by":"crossref","unstructured":"M.E. Peichoto, F.L. Tavares, M.L. Santoro, S.P. Mackessy, S. P. (2012). Venom proteomes of South and North American opisthoglyphous (Colubridae and Dipsadidae) snake species: a preliminary approach to understanding their biological roles. Comp. Biochem. Physiol. D Genom. Proteom. 7 (2012) 361\u2013369.","DOI":"10.1016\/j.cbd.2012.08.001"},{"key":"10.1016\/j.jprot.2020.103882_bb0415","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.jprot.2018.08.004","article-title":"Transcriptome-facilitated proteomic characterization of rear-fanged snake venoms reveal abundant metalloproteinases with enhanced activity","volume":"187","author":"Modahl","year":"2018","journal-title":"J. Proteomics"},{"key":"10.1016\/j.jprot.2020.103882_bb0420","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.jmb.2005.05.020","article-title":"Crystal structure of a CRISP family Ca2+-channel blocker derived from snake venom","volume":"350","author":"Shikamoto","year":"2005","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.jprot.2020.103882_bb0425","doi-asserted-by":"crossref","first-page":"4289","DOI":"10.1529\/biophysj.108.137224","article-title":"Structural and functional characterization of ryanodine receptor-natrin toxin interaction","volume":"95","author":"Zhou","year":"2008","journal-title":"Biophys. J."},{"key":"10.1016\/j.jprot.2020.103882_bb0430","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1046\/j.1365-2125.2000.00159.x","article-title":"Ion channels and the control of blood pressure","volume":"49","author":"Baker","year":"2000","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jprot.2020.103882_bb0435","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-56643-0","article-title":"An in vivo examination of the differences between rapid cardiovascular collapse and prolonged hypotension induced by snake venom","volume":"9","author":"Kakumanu","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jprot.2020.103882_bb0440","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/s00239-003-2461-2","article-title":"Molecular evolution and phylogeny of elapid snake venom three-finger toxins","volume":"57","author":"Fry","year":"2003","journal-title":"J. Mol. Evol."},{"key":"10.1016\/j.jprot.2020.103882_bb0445","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/s00239-017-9825-5","article-title":"Ancient diversification of three-finger toxins in Micrurus coral snakes","volume":"86","author":"Dashevsky","year":"2018","journal-title":"J. Mol. Evol."},{"key":"10.1016\/j.jprot.2020.103882_bb0450","article-title":"Three-finger toxin diversification in the venoms of cat-eye snakes (Colubridae: Boiga)","author":"Dashevsky","year":"2018","journal-title":"J. Mol. Evol."},{"key":"10.1016\/j.jprot.2020.103882_bb0455","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1534\/genetics.117.202655","article-title":"Selection to increase expression, not sequence diversity, precedes gene family origin and expansion in rattlesnake venom","volume":"206","author":"Margres","year":"2017","journal-title":"Genetics"},{"key":"10.1016\/j.jprot.2020.103882_bb0460","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.toxicon.2010.07.010","article-title":"Structure, function and evolution of three-finger toxins: mini proteins with multiple targets","volume":"56","author":"Kini","year":"2010","journal-title":"Toxicon"},{"key":"10.1016\/j.jprot.2020.103882_bb0465","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.toxicon.2012.09.007","article-title":"Three-finger toxins, a deadly weapon of elapid venom--milestones of discovery","volume":"62","author":"Utkin","year":"2013","journal-title":"Toxicon"},{"key":"10.1016\/j.jprot.2020.103882_bb0470","series-title":"Venomous Reptiles and Their Toxins: Evolution, Pathophysiology and Biodiscovery (B.G. Fry, Editor)","first-page":"215","article-title":"Three-finger toxins (3FTxs)","author":"Utkin","year":"2015"},{"key":"10.1016\/j.jprot.2020.103882_bb0475","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/jnc.13975","article-title":"The three-finger toxin fold: a multifunctional structural scaffold able to modulate cholinergic functions","volume":"142","author":"Kessler","year":"2017","journal-title":"J. Neurochem."},{"key":"10.1016\/j.jprot.2020.103882_bb0480","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1254\/jphs.94.1","article-title":"Three-finger \u03b1-neurotoxins and the nicotinic acetylcholine receptor, forty years on","volume":"94","author":"Nirthanan","year":"2004","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.jprot.2020.103882_bb0485","doi-asserted-by":"crossref","first-page":"222","DOI":"10.3109\/15563650.2015.1135337","article-title":"Coral snake bites (Micrurus spp.) in Brazil: a review of literature reports","volume":"54","author":"Bucaretchi","year":"2016","journal-title":"Clin. Toxicol."},{"key":"10.1016\/j.jprot.2020.103882_bb0490","doi-asserted-by":"crossref","first-page":"15810","DOI":"10.1074\/jbc.M100788200","article-title":"E.V., Kryukova, F. Chiodini, D. Bertrand, C. Methfessel, V.I. Tsetlin VI (2001) \u201cWeak toxin\u201d from Naja kaouthia is a nontoxic antagonist of \u03b17 and muscle-type nicotinic acetylcholine receptors","volume":"276","author":"Utkin","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jprot.2020.103882_bb0495","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0041-0101(02)00388-4","article-title":"Non-conventional toxins from elapid venoms","volume":"41","author":"Nirthanan","year":"2003","journal-title":"Toxicon"},{"key":"10.1016\/j.jprot.2020.103882_bb0500","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1016\/j.biochi.2013.06.025","article-title":"Identification and characterization of a taxon-specific three-finger toxin from the venom of the green vinesnake (Oxybelis fulgidus; family Colubridae)","volume":"95","author":"Heyborne","year":"2013","journal-title":"Biochimie"},{"key":"10.1016\/j.jprot.2020.103882_bb0505","doi-asserted-by":"crossref","first-page":"29030","DOI":"10.1074\/jbc.M605850200","article-title":"Denmotoxin, a three-finger toxin from the colubrid snake Boiga dendrophila (mangrove catsnake) with bird-specific activity","volume":"281","author":"Pawlak","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.jprot.2020.103882_bb0510","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1096\/fj.08-113555","article-title":"Irditoxin, a novel covalently linked heterodimeric three-finger toxin with high taxon-specific neurotoxicity","volume":"23","author":"Pawlak","year":"2008","journal-title":"FASEB J."},{"key":"10.1016\/j.jprot.2020.103882_bb0515","first-page":"425","article-title":"Prey specificity, comparative lethality and compositional differences of coral snake venoms","volume":"128","author":"da Silva","year":"2001","journal-title":"Comp. Biochem. Physiol. C: Toxicol. Pharmacol."},{"key":"10.1016\/j.jprot.2020.103882_bb0520","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1111\/jzs.12202","article-title":"Aquatic adaptations in a Neotropical coral snake: a study of morphological convergence","volume":"56","author":"Silva","year":"2018","journal-title":"J. Zool. Syst. Evol. Res."},{"key":"10.1016\/j.jprot.2020.103882_bb0525","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1890\/0012-9658(1997)078[1049:SPBJWP]2.0.CO;2","article-title":"Selective predation by juvenile weakfish: post-consumptive constraints on energy maximization and growth","volume":"78","author":"Lankford","year":"1997","journal-title":"Ecology"},{"key":"10.1016\/j.jprot.2020.103882_bb0530","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1111\/j.1365-2656.2008.01512.x","article-title":"Towards a predictive framework for predator risk effects: the interaction of landscape features and prey escape tactics","volume":"78","author":"Heithaus","year":"2009","journal-title":"J. Anim. Ecol."},{"key":"10.1016\/j.jprot.2020.103882_bb0535","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1890\/10-2222.1","article-title":"The effects of variable predation risk on foraging and growth: less risk is not necessarily better","volume":"92","author":"Trussell","year":"2011","journal-title":"Ecology"},{"key":"10.1016\/j.jprot.2020.103882_bb0540","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.toxicon.2012.11.022","article-title":"The venom optimization hypothesis revisited","volume":"63","author":"Morgenstern","year":"2013","journal-title":"Toxicon"},{"key":"10.1016\/j.jprot.2020.103882_bb0545","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.toxicon.2017.10.026","article-title":"Coevolution takes the sting out of it: evolutionary biology and mechanisms of toxin resistance in animals","volume":"140","author":"Arbuckle","year":"2017","journal-title":"Toxicon"},{"key":"10.1016\/j.jprot.2020.103882_bb0550","doi-asserted-by":"crossref","DOI":"10.1098\/rsbl.2018.0876","article-title":"High levels of functional divergence in toxicity towards prey among the venoms of individual pigmy rattlesnakes","volume":"15","author":"Smiley-Walters","year":"2019","journal-title":"Biol. Lett."},{"key":"10.1016\/j.jprot.2020.103882_bb0555","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.toxicon.2019.09.011","article-title":"Predator-prey interactions and venom composition in a high elevation lizard specialist, Crotalus pricei (twin-spotted rattlesnake)","volume":"170","author":"Grabowsky","year":"2019","journal-title":"Toxicon"},{"key":"10.1016\/j.jprot.2020.103882_bb0560","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1111\/ele.13216","article-title":"Snake venom potency and yield are associated with prey-evolution, predator metabolism and habitat structure","volume":"22","author":"Healy","year":"2019","journal-title":"Ecol. Lett."},{"key":"10.1016\/j.jprot.2020.103882_bb0565","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/379537a0","article-title":"Diet and snake venom evolution","volume":"379","author":"Daltry","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.jprot.2020.103882_bb0570","first-page":"2443","article-title":"Coevolution of diet and prey-specific venom activity supports the role of selection in snake venom evolution","volume":"276","author":"Barlow","year":"2009","journal-title":"Proc. Biol. Sci."},{"key":"10.1016\/j.jprot.2020.103882_bb0575","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1093\/molbev\/msz125","article-title":"Many options, few solutions: over 60 my snakes converged on a few optimal venom formulations","volume":"36","author":"Barua","year":"2019","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.jprot.2020.103882_bb0580","doi-asserted-by":"crossref","first-page":"E711","DOI":"10.3390\/toxins11120711","article-title":"Coevolution of Snake venom toxic activities and diet: evidence that ecological Generalism favours toxicological diversity","volume":"11","author":"Davies","year":"2019","journal-title":"Toxins"},{"key":"10.1016\/j.jprot.2020.103882_bb0585","doi-asserted-by":"crossref","first-page":"644","DOI":"10.2307\/1447225","article-title":"Venom delivery of snakes as high\u2013pressure and low\u2013pressure systems","author":"Kardong","year":"1993","journal-title":"Copeia"}],"container-title":["Journal of Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391920302505?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391920302505?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T12:05:28Z","timestamp":1761739528000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1874391920302505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":117,"alternative-id":["S1874391920302505"],"URL":"https:\/\/doi.org\/10.1016\/j.jprot.2020.103882","relation":{},"ISSN":["1874-3919"],"issn-type":[{"value":"1874-3919","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Venomics of the Duvernoy's gland secretion of the false coral snake Rhinobothryum bovallii (Andersson, 1916) and assessment of venom lethality towards synapsid and diapsid animal models","name":"articletitle","label":"Article Title"},{"value":"Journal of Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jprot.2020.103882","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103882"}}