{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T21:01:36Z","timestamp":1791838896057,"version":"4.3.4"},"reference-count":89,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Proteomics"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.jprot.2022.104665","type":"journal-article","created":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T12:18:06Z","timestamp":1655986686000},"page":"104665","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["The proteomics of the freshwater pearl powder: Insights from biomineralization to biomedical application"],"prefix":"10.1016","volume":"265","author":[{"given":"Wen","family":"Luo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jprot.2022.104665_bb0005","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.2174\/0929866511320100012","article-title":"Proteomic and profile analysis of the proteins laced with aragonite and vaterite in the freshwater mussel Hyriopsis cumingii shell biominerals","volume":"20","author":"Berland","year":"2013","journal-title":"Protein Pept. Lett."},{"key":"10.1016\/j.jprot.2022.104665_bb0010","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1016\/j.msec.2012.12.057","article-title":"What is the difference in organic matrix of aragonite vs. vaterite polymorph in natural shell and pearl? Study of the pearl-forming freshwater bivalve mollusc Hyriopsis cumingii","volume":"33","author":"Ma","year":"2013","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.jprot.2022.104665_bb0015","doi-asserted-by":"crossref","first-page":"20200157","DOI":"10.1098\/rstb.2020.0157","article-title":"MolluscDB: a genome and transcriptome database for molluscs","volume":"376","author":"Caurcel","year":"2021","journal-title":"Philos. T. R. Soc. B"},{"key":"10.1016\/j.jprot.2022.104665_bb0020","doi-asserted-by":"crossref","first-page":"1900036","DOI":"10.1002\/pmic.201900036","article-title":"The biomineralization proteome: protein complexity for a complex bioceramic assembly process","volume":"19","author":"Evans","year":"2019","journal-title":"Proteomics"},{"key":"10.1016\/j.jprot.2022.104665_bb0025","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1093\/molbev\/msw219","article-title":"Insights from the shell proteome: biomineralization to adaptation","volume":"34","author":"Arivalagan","year":"2017","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.jprot.2022.104665_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.jsb.2020.107583","article-title":"Mollusc shellomes: past, present and future","volume":"212","author":"Marin","year":"2020","journal-title":"J. Struct. Biol."},{"key":"10.1016\/j.jprot.2022.104665_bb0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.jprot.2021.104171","article-title":"Biomineral proteomics: a tool for multiple disciplinary studies","volume":"238","author":"Liu","year":"2021","journal-title":"J. Proteome"},{"key":"10.1016\/j.jprot.2022.104665_bb0040","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.fsi.2019.05.012","article-title":"Integrated transcriptome analysis of immunological responses in the pearl sac of the triangle sail mussel (Hyriopsis cumingii) after mantle implantation","volume":"90","author":"Huang","year":"2019","journal-title":"Fish Shellfish Immun."},{"key":"10.1016\/j.jprot.2022.104665_bb0045","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1186\/s12864-019-5579-3","article-title":"Gene expression profiles at different stages for formation of pearl sac and pearl in the pearl oyster Pinctada fucata","volume":"20","author":"Mariom","year":"2019","journal-title":"BMC Genomics"},{"key":"10.1016\/j.jprot.2022.104665_bb0050","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2020.597459","article-title":"Pearl sac gene expression profiles associated with pearl attributes in the silver-lip pearl oyster, Pinctada maxima","volume":"11","author":"McDougall","year":"2021","journal-title":"Front. Genet."},{"key":"10.1016\/j.jprot.2022.104665_bb0055","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.margen.2011.08.006","article-title":"Transcriptome analysis of biomineralisation-related genes within the pearl sac: host and donor oyster contribution","volume":"5","author":"McGinty","year":"2012","journal-title":"Mar. Genomics"},{"key":"10.1016\/j.jprot.2022.104665_bb0060","doi-asserted-by":"crossref","first-page":"256","DOI":"10.3389\/fmars.2020.00256","article-title":"Histological and comparative transcriptome analyses provide insights into the immune response in pearl sac formation of Hyriopsis cumingii","volume":"7","author":"Shen","year":"2020","journal-title":"Front. Mar. Sci."},{"key":"10.1016\/j.jprot.2022.104665_bb0065","series-title":"Goods and Services of Marine Bivalves","first-page":"73","article-title":"Production of pearls","author":"Zhu","year":"2019"},{"key":"10.1016\/j.jprot.2022.104665_bb0070","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.jep.2016.01.039","article-title":"Anticonvulsant and sedative-hypnotic activity screening of pearl and nacre (mother of pearl)","volume":"181","author":"Zhang","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jprot.2022.104665_bb0075","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1016\/j.msec.2011.04.016","article-title":"Characterization of organic matrix extracted from fresh water pearls","volume":"31","author":"Ma","year":"2011","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.jprot.2022.104665_bb0080","doi-asserted-by":"crossref","first-page":"2797","DOI":"10.3390\/ma14112797","article-title":"Pearl powder-an emerging material for biomedical applications: a review","volume":"14","author":"Loh","year":"2021","journal-title":"Materials"},{"key":"10.1016\/j.jprot.2022.104665_bb0085","doi-asserted-by":"crossref","first-page":"2797","DOI":"10.3389\/fbioe.2021.649665","article-title":"Extraction, purification, bioactivities and application of matrix proteins from pearl powder and nacre powder: a review","volume":"9","author":"Pei","year":"2021","journal-title":"Front. Bioeng. Biotech."},{"key":"10.1016\/j.jprot.2022.104665_bb0090","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.biomaterials.2005.05.088","article-title":"In vitro osteogenetic activity of pearl","volume":"27","author":"Shen","year":"2006","journal-title":"Biomaterials"},{"key":"10.1016\/j.jprot.2022.104665_bb0095","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1080\/09205063.2018.1475096","article-title":"Three dimensionally printed pearl powder\/poly-caprolactone composite scaffolds for bone regeneration","volume":"29","author":"Zhang","year":"2018","journal-title":"J. Biomat. Sci. Polym. E."},{"key":"10.1016\/j.jprot.2022.104665_bb0100","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.jfda.2017.05.010","article-title":"Efficacy of protein rich pearl powder on antioxidant status in a randomized placebo-controlled trial","volume":"26","author":"Chiu","year":"2018","journal-title":"J. Food Drug Anal."},{"key":"10.1016\/j.jprot.2022.104665_bb0105","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1096\/fj.201700422R","article-title":"PFMG1 promotes osteoblast differentiation and prevents osteoporotic bone loss","volume":"32","author":"Li","year":"2018","journal-title":"FASEB J."},{"key":"10.1016\/j.jprot.2022.104665_bb0110","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1016\/j.ijbiomac.2019.10.159","article-title":"N16 suppresses RANKL-mediated osteoclatogenesis by down-regulating RANK expression","volume":"151","author":"Lin","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jprot.2022.104665_bb0115","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2021.674539","article-title":"The \u2018Shellome\u2019 of the crocus clam Tridacna crocea emphasizes essential components of mollusk shell biomineralization","volume":"12","author":"Takeuchi","year":"2021","journal-title":"Front. Genet."},{"key":"10.1016\/j.jprot.2022.104665_bb0120","doi-asserted-by":"crossref","first-page":"17269","DOI":"10.1038\/srep17269","article-title":"In-depth proteomic analysis of shell matrix proteins of Pinctada fucata","volume":"5","author":"Liu","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jprot.2022.104665_bb0125","article-title":"Comparative analysis of the transcriptome in tissues secreting purple and white nacre in the pearl mussel Hyriopsis cumingii","volume":"8","author":"Bai","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jprot.2022.104665_bb0130","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1006\/jsbi.2001.4372","article-title":"Structure of the nacreous organic matrix of a bivalve mollusk shell examined in the hydrated state using cryo-TEM","volume":"135","author":"Levi-Kalisman","year":"2001","journal-title":"J. Struct. Biol."},{"key":"10.1016\/j.jprot.2022.104665_bb0135","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/1477-5956-8-54","article-title":"Proteomic analysis of the organic matrix of the abalone Haliotis asinina calcified shell","volume":"8","author":"Marie","year":"2010","journal-title":"Proteome Sci."},{"key":"10.1016\/j.jprot.2022.104665_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.jsb.2020.107497","article-title":"The shell matrix of the european thorny oyster, Spondylus gaederopus: microstructural and molecular characterization","volume":"211","author":"Sakalauskaite","year":"2020","journal-title":"J. Struct. Biol."},{"key":"10.1016\/j.jprot.2022.104665_bb0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpb.2021.110641","article-title":"Review: post-translational modifications of marine shell matrix proteins","volume":"256","author":"Rivera-Perez","year":"2021","journal-title":"Comp. Biochem. Physiol. B"},{"key":"10.1016\/j.jprot.2022.104665_bb0150","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.actbio.2018.09.009","article-title":"Biomacromolecules within bivalve shells: is chitin abundant?","volume":"80","author":"Agbaje","year":"2018","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jprot.2022.104665_bb0155","doi-asserted-by":"crossref","first-page":"100","DOI":"10.3389\/fphys.2020.00100","article-title":"A novel tyrosinase gene plays a potential role in modification the shell organic matrix of the triangle mussel Hyriopsis cumingii","volume":"11","author":"Ren","year":"2020","journal-title":"Front. Physiol."},{"key":"10.1016\/j.jprot.2022.104665_bb0160","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/1477-5956-12-28","article-title":"The Lottia gigantea shell matrix proteome: re-analysis including MaxQuant iBAQ quantitation and phosphoproteome analysis","volume":"12","author":"Mann","year":"2014","journal-title":"Proteome Sci."},{"key":"10.1016\/j.jprot.2022.104665_bb0165","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s12983-016-0155-z","article-title":"Sea shell diversity and rapidly evolving secretomes: insights into the evolution of biomineralization","volume":"13","author":"Kocot","year":"2016","journal-title":"Front. Zool."},{"key":"10.1016\/j.jprot.2022.104665_bb0170","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1111\/febs.12062","article-title":"The shell-forming proteome of Lottia gigantea reveals both deep conservations and lineage-specific novelties","volume":"280","author":"Marie","year":"2013","journal-title":"FEBS J."},{"key":"10.1016\/j.jprot.2022.104665_bb0175","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.ijbiomac.2017.03.154","article-title":"Hyriopsis cumingii Hic52-a novel nacreous layer matrix protein with a collagen-like structure","volume":"102","author":"Liu","year":"2017","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jprot.2022.104665_bb0180","doi-asserted-by":"crossref","first-page":"9657","DOI":"10.1073\/pnas.93.18.9657","article-title":"A carbonic anhydrase from the nacreous layer in oyster pearls","volume":"93","author":"Miyamoto","year":"1996","journal-title":"PNAS"},{"key":"10.1016\/j.jprot.2022.104665_bb0185","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1111\/j.1365-2109.2009.02199.x","article-title":"High levels of intra-specific variation in the NG repeat region of the Pinctada maxima N66 organic matrix protein","volume":"40","author":"Smith-Keune","year":"2009","journal-title":"Aquac. Res."},{"key":"10.1016\/j.jprot.2022.104665_bb0190","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1126\/science.1173793","article-title":"An acidic matrix protein, Pif, is a key macromolecule for nacre formation","volume":"325","author":"Suzuki","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.jprot.2022.104665_bb0195","doi-asserted-by":"crossref","first-page":"3109","DOI":"10.1002\/pmic.201300162","article-title":"Proteomics of CaCO3 biomineral-associated proteins: how to properly address their analysis","volume":"13","author":"Marie","year":"2013","journal-title":"Proteomics"},{"key":"10.1016\/j.jprot.2022.104665_bb0200","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1126\/science.1090506","article-title":"Hemocyte-mediated shell mineralization in the eastern oyster","volume":"304","author":"Mount","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.jprot.2022.104665_bb0205","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.fsi.2016.02.027","article-title":"Hemocytes participate in calcium carbonate crystal formation, transportation and shell regeneration in the pearl oyster Pinctada fucata","volume":"51","author":"Li","year":"2016","journal-title":"Fish Shellfish Immun."},{"key":"10.1016\/j.jprot.2022.104665_bb0210","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/nature11413","article-title":"The oyster genome reveals stress adaptation and complexity of shell formation","volume":"490","author":"Zhang","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.jprot.2022.104665_bb0215","article-title":"The mantle exosome proteins of Hyriopsis cumingii participate in shell and nacre color formation","volume":"39","author":"Chen","year":"2021","journal-title":"Comp. Biochem. Phys. D"},{"key":"10.1016\/j.jprot.2022.104665_bb0220","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12953-018-0139-3","article-title":"In-depth proteomic analyses of Haliotis laevigata (greenlip abalone) nacre and prismatic organic shell matrix","volume":"16","author":"Mann","year":"2018","journal-title":"Proteome Sci."},{"key":"10.1016\/j.jprot.2022.104665_bb0225","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1080\/03639045.2019.1593436","article-title":"Nanoscaled pearl powder accelerates wound repair and regeneration in vitro and in vivo","volume":"45","author":"Chen","year":"2019","journal-title":"Drug Dev. Ind. Pharm."},{"key":"10.1016\/j.jprot.2022.104665_bb0230","doi-asserted-by":"crossref","first-page":"122","DOI":"10.3109\/13880200903046211","article-title":"Effects of pearl powder extract and its fractions on fibroblast function relevant to wound repair","volume":"48","author":"Dai","year":"2010","journal-title":"Pharm. Biol."},{"key":"10.1016\/j.jprot.2022.104665_bb0235","doi-asserted-by":"crossref","first-page":"3211","DOI":"10.1007\/s11033-011-1088-4","article-title":"Nacre-driven water-soluble factors promote wound healing of the deep burn porcine skin by recovering angiogenesis and fibroblast function","volume":"39","author":"Lee","year":"2012","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.jprot.2022.104665_bb0240","doi-asserted-by":"crossref","first-page":"289","DOI":"10.3109\/13880209.2012.721130","article-title":"Pearl extract enhances the migratory ability of fibroblasts in a wound healing model","volume":"51","author":"Li","year":"2013","journal-title":"Pharm. Biol."},{"key":"10.1016\/j.jprot.2022.104665_bb0245","doi-asserted-by":"crossref","first-page":"4458","DOI":"10.3390\/ma14164458","article-title":"Efficacy of water-soluble pearl powder components extracted by a CO2 supercritical extraction system in promoting wound healing","volume":"14","author":"Liu","year":"2021","journal-title":"Materials (Basel)"},{"key":"10.1016\/j.jprot.2022.104665_bb0250","doi-asserted-by":"crossref","first-page":"5947","DOI":"10.3390\/jcm10245947","article-title":"The role of extracellular matrix in skin wound healing","volume":"10","author":"Potekaev","year":"2021","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.jprot.2022.104665_bb0255","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1101\/gad.1387406","article-title":"Keratin 17 modulates hair follicle cycling in a TNF alpha-dependent fashion","volume":"20","author":"Tong","year":"2006","journal-title":"Genes Dev."},{"key":"10.1016\/j.jprot.2022.104665_bb0260","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1007\/s00418-008-0435-6","article-title":"The human keratins: biology and pathology","volume":"129","author":"Moll","year":"2008","journal-title":"Histochem. Cell Biol."},{"key":"10.1016\/j.jprot.2022.104665_bb0265","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0042271","article-title":"Fibroin and sericin from Bombyx mori silk stimulate cell migration through upregulation and phosphorylation of c-Jun","volume":"7","author":"Martinez-Mora","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.jprot.2022.104665_bb0270","doi-asserted-by":"crossref","first-page":"3537","DOI":"10.3390\/polym13203537","article-title":"Cutaneous regeneration mechanism of \u03b2-sheet silk fibroin in a rat burn wound healing model","volume":"13","author":"Chou","year":"2021","journal-title":"Polymers-Basel"},{"key":"10.1016\/j.jprot.2022.104665_bb0275","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/0092-8674(95)90517-0","article-title":"Crystal structure of the a domain from the alpha subunit of integrin CR3 (CD11B\/CD18)","volume":"80","author":"Lee","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.jprot.2022.104665_bb0280","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1006\/jmbi.1993.1305","article-title":"The CUB domain: a widespread module in developmentally regulated proteins","volume":"231","author":"Bork","year":"1993","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.jprot.2022.104665_bb0285","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1042\/bj2920947","article-title":"Evolution of the hyaluronan-binding module of link protein","volume":"292","author":"Barta","year":"1993","journal-title":"Biochem. J."},{"key":"10.1016\/j.jprot.2022.104665_bb0290","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/S0092-8674(00)80151-8","article-title":"Solution structure of the link module: a hyaluronan-binding domain involved in extracellular matrix stability and cell migration","volume":"86","author":"Kohda","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.jprot.2022.104665_bb0295","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.actbio.2017.03.003","article-title":"Design strategies and applications of nacre-based biomaterials","volume":"54","author":"Gerhard","year":"2017","journal-title":"Acta Biomater."},{"key":"10.1016\/j.jprot.2022.104665_bb0300","doi-asserted-by":"crossref","first-page":"65001","DOI":"10.1088\/1748-6041\/8\/6\/065001","article-title":"3D scaffold of PLLA\/pearl and PLLA\/nacre powder for bone regeneration","volume":"8","author":"Liu","year":"2013","journal-title":"Biomed. Mater."},{"key":"10.1016\/j.jprot.2022.104665_bb0305","doi-asserted-by":"crossref","first-page":"7489","DOI":"10.1016\/j.biomaterials.2012.06.098","article-title":"The role of nacreous factors in preventing osteoporotic bone loss through both osteoblast activation and osteoclast inactivation","volume":"33","author":"Kim","year":"2012","journal-title":"Biomaterials"},{"key":"10.1016\/j.jprot.2022.104665_bb0310","doi-asserted-by":"crossref","DOI":"10.1111\/jfbc.13890","article-title":"Production and identification of peptides with activity promoting osteoblast proliferation from meat dregs of Pinctada martensii","volume":"45","author":"Tian","year":"2021","journal-title":"J. Food Biochem."},{"key":"10.1016\/j.jprot.2022.104665_bb0315","doi-asserted-by":"crossref","first-page":"5616","DOI":"10.1039\/C9FO01201J","article-title":"Bone formation activity of an osteogenic dodecapeptide from blue mussels (Mytilus edulis)","volume":"10","author":"Xu","year":"2019","journal-title":"Food Funct."},{"key":"10.1016\/j.jprot.2022.104665_bb0320","doi-asserted-by":"crossref","first-page":"866","DOI":"10.3390\/antiox9090866","article-title":"Anti-osteoporotic effects of antioxidant peptides PIISVYWK and FSVVPSPK from Mytilus edulis on ovariectomized mice","volume":"9","author":"Oh","year":"2020","journal-title":"Antioxidants"},{"key":"10.1016\/j.jprot.2022.104665_bb0325","doi-asserted-by":"crossref","first-page":"510","DOI":"10.3390\/md18100510","article-title":"Blue mussel-derived peptides PIISVYWK and FSVVPSPK trigger Wnt\/\u03b2-catenin signaling-mediated osteogenesis in human bone marrow mesenchymal stem cells","volume":"18","author":"Oh","year":"2020","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.jprot.2022.104665_bb0330","doi-asserted-by":"crossref","first-page":"472","DOI":"10.3390\/md18090472","article-title":"Fermented oyster extract promotes insulin-like growth factor-1-mediated osteogenesis and growth rate","volume":"18","author":"Molagoda","year":"2020","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.jprot.2022.104665_bb0335","doi-asserted-by":"crossref","first-page":"13522","DOI":"10.1073\/pnas.1607644113","article-title":"Decreasing maternal myostatin programs adult offspring bone strength in a mouse model of osteogenesis imperfecta","volume":"113","author":"Oestreich","year":"2016","journal-title":"P. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jprot.2022.104665_bb0340","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2021.662908","article-title":"Deciphering myostatin's regulatory, metabolic, and developmental influence in skeletal diseases","volume":"12","author":"Omosule","year":"2021","journal-title":"Front. Genet."},{"key":"10.1016\/j.jprot.2022.104665_bb0345","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0084584","article-title":"Water soluble bioactives of nacre mediate antioxidant activity and osteoblast differentiation","volume":"8","author":"Chaturvedi","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jprot.2022.104665_bb0350","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1016\/j.freeradbiomed.2012.02.037","article-title":"Protein disulfide isomerase in redox cell signaling and homeostasis","volume":"52","author":"Laurindo","year":"2012","journal-title":"Free Radical Bio. Med."},{"key":"10.1016\/j.jprot.2022.104665_bb0355","doi-asserted-by":"crossref","first-page":"4956","DOI":"10.1111\/jcmm.15095","article-title":"Pearl powder reduces sleep disturbance stress response through regulating proteomics in a rat model of sleep deprivation","volume":"24","author":"Xia","year":"2020","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.jprot.2022.104665_bb0360","doi-asserted-by":"crossref","first-page":"7102","DOI":"10.1073\/pnas.102192599","article-title":"The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling","volume":"99","author":"Roncarati","year":"2002","journal-title":"P. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.jprot.2022.104665_bb0365","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S1046-5928(02)00684-8","article-title":"Expression and characterization of human bifunctional peptidylglycine alpha-amidating monooxygenase","volume":"28","author":"Satani","year":"2003","journal-title":"Protein Expr. Purif."},{"key":"10.1016\/j.jprot.2022.104665_bb0370","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0026-895X(24)12146-3","article-title":"Subtype-selective inhibition of neuronal nicotinic acetylcholine receptors by cocaine is determined by the alpha 4 and beta 4 subunits","volume":"58","author":"Francis","year":"2000","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.jprot.2022.104665_bb0375","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1007\/s00439-018-1929-5","article-title":"Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies)","volume":"137","author":"Bramswig","year":"2018","journal-title":"Hum. Genet."},{"key":"10.1016\/j.jprot.2022.104665_bb0380","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1002\/pro.3587","article-title":"Structural characterization of the third scavenger receptor cysteine-rich domain of murine neurotrypsin","volume":"28","author":"Canciani","year":"2019","journal-title":"Protein Sci."},{"key":"10.1016\/j.jprot.2022.104665_bb0385","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1111\/jocd.13899","article-title":"Soluble pearl extract provides effective skin lightening by antagonizing endothelin","volume":"20","author":"Wang","year":"2021","journal-title":"J. Cosmet. Dermatol. US"},{"key":"10.1016\/j.jprot.2022.104665_bb0390","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.it.2008.02.009","article-title":"The proPO-system: pros and cons for its role in invertebrate immunity","volume":"29","author":"Cerenius","year":"2008","journal-title":"Trends Immunol."},{"key":"10.1016\/j.jprot.2022.104665_bb0395","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1111\/ics.12466","article-title":"Intrinsic and extrinsic regulation of human skin melanogenesis and pigmentation","volume":"40","author":"Serre","year":"2018","journal-title":"Int. J. Cosmet. Sci."},{"key":"10.1016\/j.jprot.2022.104665_bb0400","first-page":"S139","article-title":"Anti-inflammation and anti-apoptosis effects of pearl extract gel on UVB irradiation HaCaT cells","volume":"261","author":"Yang","year":"2015","journal-title":"Bio-Med. Mater. Eng."},{"key":"10.1016\/j.jprot.2022.104665_bb0405","series-title":"Annual Review of Physiology, Palo Alto","first-page":"479","article-title":"Role of chitin and chitinase\/chitinase-like proteins in inflammation, tissue remodeling, and injury","author":"Lee","year":"2011"},{"key":"10.1016\/j.jprot.2022.104665_bb0410","first-page":"1735","article-title":"Thrombospondin 1 and type I repeat peptides of thrombospondin 1 specifically induce apoptosis of endothelial cells","volume":"57","author":"Guo","year":"1997","journal-title":"Cancer Res."},{"key":"10.1016\/j.jprot.2022.104665_bb0415","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s10495-010-0571-z","article-title":"Structural analyses of death domains and their interactions","volume":"16","author":"Park","year":"2011","journal-title":"Apoptosis"},{"key":"10.1016\/j.jprot.2022.104665_bb0420","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jip.2015.05.005","article-title":"Immune responses to infectious diseases in bivalves","volume":"131","author":"Allam","year":"2015","journal-title":"J. Invertebr. Pathol."},{"key":"10.1016\/j.jprot.2022.104665_bb0425","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.marpolbul.2017.06.031","article-title":"Recent findings on phenoloxidases in bivalves","volume":"122","author":"Luna-Acosta","year":"2017","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.jprot.2022.104665_bb0430","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.cub.2013.01.058","article-title":"Calcium flashes orchestrate the wound inflammatory response through DUOX activation and hydrogen peroxide release","volume":"23","author":"Razzell","year":"2013","journal-title":"Curr. Biol."},{"key":"10.1016\/j.jprot.2022.104665_bb0435","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1007\/s10528-021-10046-x","article-title":"Release of mediator enzyme beta-hexosaminidase and modulated gene expression accompany hemocyte degranulation in response to parasitism in the silkworm Bombyx mori","volume":"59","author":"Prabhuling","year":"2021","journal-title":"Biochem. Genet."},{"key":"10.1016\/j.jprot.2022.104665_bb0440","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1038\/s41419-020-2535-8","article-title":"The novel miR-1269b-regulated protein SVEP1 induces hepatocellular carcinoma proliferation and metastasis likely through the PI3K\/Akt pathway","volume":"11","author":"Chen","year":"2020","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.jprot.2022.104665_bb0445","article-title":"Heat shock proteins as immunomodulants","volume":"2846","author":"Zininga","year":"2018","journal-title":"Molecules"}],"container-title":["Journal of Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391922001890?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391922001890?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T12:13:28Z","timestamp":1761740008000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1874391922001890"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":89,"alternative-id":["S1874391922001890"],"URL":"https:\/\/doi.org\/10.1016\/j.jprot.2022.104665","relation":{},"ISSN":["1874-3919"],"issn-type":[{"value":"1874-3919","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The proteomics of the freshwater pearl powder: Insights from biomineralization to biomedical application","name":"articletitle","label":"Article Title"},{"value":"Journal of Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jprot.2022.104665","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"104665"}}