{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T04:30:48Z","timestamp":1749616248001,"version":"3.37.3"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100014125","name":"Fujian Provincial Health Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014125","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005270","name":"Fujian Provincial Department of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005270","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Proteomics"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.jprot.2024.105287","type":"journal-article","created":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T03:20:07Z","timestamp":1724383207000},"page":"105287","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Combining proteomics and Phosphoproteomics to investigate radiation-induced rectal fibrosis in rats and the effects of pSTAT3 inhibitor S3I-201 on human intestinal fibroblasts"],"prefix":"10.1016","volume":"308","author":[{"given":"Hongfeng","family":"Pan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeyi","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanchang","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yihuang","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haoyang","family":"Ruan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pan","family":"Chi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shenghui","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.jprot.2024.105287_bb0005","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1056\/NEJMoa2303269","article-title":"Preoperative Treatment of Locally Advanced Rectal Cancer","volume":"389","author":"Schrag","year":"2023","journal-title":"N. Engl. J. Med."},{"issue":"10","key":"10.1016\/j.jprot.2024.105287_bb0010","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24108800","article-title":"Characterization of early and late damage in a mouse model of pelvic radiation disease","volume":"24","author":"Vitali","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"7","key":"10.1016\/j.jprot.2024.105287_bb0015","first-page":"1309","article-title":"Radiation proctitis: a review","volume":"91","author":"Babb","year":"1996","journal-title":"Am. J. Gastroenterol."},{"issue":"31","key":"10.1016\/j.jprot.2024.105287_bb0020","doi-asserted-by":"crossref","first-page":"3773","DOI":"10.1200\/JCO.2016.67.6049","article-title":"Effect of interval (7 or 11 weeks) between neoadjuvant Radiochemotherapy and surgery on complete pathologic response in rectal Cancer: a multicenter, randomized, controlled trial (GRECCAR-6)","volume":"34","author":"Lefevre","year":"2016","journal-title":"J. Clin. Oncol."},{"issue":"3","key":"10.1016\/j.jprot.2024.105287_bb0025","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.radonc.2016.06.006","article-title":"Dose-volume effect relationships for late rectal morbidity in patients treated with chemoradiation and MRI-guided adaptive brachytherapy for locally advanced cervical cancer: results from the prospective multicenter EMBRACE study","volume":"120","author":"Mazeron","year":"2016","journal-title":"Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology"},{"issue":"3","key":"10.1016\/j.jprot.2024.105287_bb0030","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.eururo.2018.12.003","article-title":"Pelvic complications after prostate Cancer radiation therapy and their management: an international collaborative narrative review","volume":"75","author":"Matta","year":"2019","journal-title":"Eur. Urol."},{"issue":"3","key":"10.1016\/j.jprot.2024.105287_bb0035","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1245\/s10434-018-07096-8","article-title":"Impact of Long-course neoadjuvant radiation on postoperative low anterior resection syndrome and quality of life in rectal Cancer: post hoc analysis of a randomized controlled trial","volume":"26","author":"Sun","year":"2019","journal-title":"Ann. Surg. Oncol."},{"issue":"17","key":"10.1016\/j.jprot.2024.105287_bb0040","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1038\/onc.2014.145","article-title":"Epigenetics in radiation-induced fibrosis","volume":"34","author":"Weigel","year":"2015","journal-title":"Oncogene"},{"key":"10.1016\/j.jprot.2024.105287_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.jprot.2020.103801","article-title":"TMT-labelled quantitative proteomic analysis to identify the proteins underlying radiation-induced colorectal fibrosis in rats","volume":"223","author":"Huang","year":"2020","journal-title":"J. Proteome"},{"issue":"4","key":"10.1016\/j.jprot.2024.105287_bb0050","first-page":"3907","article-title":"Pirfenidone suppresses TGF-\u03b21-induced human intestinal fibroblasts activities by regulating proliferation and apoptosis via the inhibition of the Smad and PI3K\/AKT signaling pathway","volume":"18","author":"Sun","year":"2018","journal-title":"Mol. Med. Rep."},{"issue":"5164","key":"10.1016\/j.jprot.2024.105287_bb0055","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1126\/science.8197455","article-title":"Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins","volume":"vol. 264","author":"Darnell","year":"1994","journal-title":"Science (New York, N.Y.)"},{"issue":"1","key":"10.1016\/j.jprot.2024.105287_bb0060","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1146\/annurev-anchem-091622-092353","article-title":"Enhanced multiplexing Technology for Proteomics","volume":"16","author":"Bowser","year":"2023","journal-title":"Annu Rev Anal Chem (Palo Alto, Calif)"},{"issue":"11","key":"10.1016\/j.jprot.2024.105287_bb0065","doi-asserted-by":"crossref","first-page":"2704","DOI":"10.1007\/s10620-014-3224-1","article-title":"Molecular mechanism of acute radiation enteritis revealed using proteomics and biological signaling network analysis in rats","volume":"59","author":"Song","year":"2014","journal-title":"Dig. Dis. Sci."},{"issue":"1","key":"10.1016\/j.jprot.2024.105287_bb0070","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1038\/s41420-022-00922-9","article-title":"Inhibition of STAT3(Y705) phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells","volume":"8","author":"Guo","year":"2022","journal-title":"Cell Death Dis."},{"issue":"3","key":"10.1016\/j.jprot.2024.105287_bb0075","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20230683","article-title":"TCR signaling induces STAT3 phosphorylation to promote TH17 cell differentiation","volume":"221","author":"Qin","year":"2024","journal-title":"J. Exp. Med."},{"issue":"2","key":"10.1016\/j.jprot.2024.105287_bb0080","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1091\/mbc.E17-06-0342","article-title":"STAT3 controls COL1A2 enhancer activation cooperatively with JunB, regulates type I collagen synthesis posttranscriptionally, and is essential for lung myofibroblast differentiation","volume":"29","author":"Papaioannou","year":"2018","journal-title":"Mol. Biol. Cell"},{"issue":"6","key":"10.1016\/j.jprot.2024.105287_bb0085","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1016\/j.kint.2016.06.038","article-title":"Fyn deficiency attenuates renal fibrosis by inhibition of phospho-STAT3","volume":"90","author":"Seo","year":"2016","journal-title":"Kidney Int."},{"issue":"12","key":"10.1016\/j.jprot.2024.105287_bb0090","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25126326","article-title":"Fibrostenosing Crohn's disease: Pathogenetic mechanisms and new therapeutic horizons","volume":"25","author":"Mignini","year":"2024","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.jprot.2024.105287_bb0095","doi-asserted-by":"crossref","DOI":"10.3390\/cancers14030552","article-title":"Inflammation, fibrosis and Cancer: mechanisms, therapeutic options and challenges","volume":"14","author":"Wu","year":"2022","journal-title":"Cancers"},{"key":"10.1016\/j.jprot.2024.105287_bb0100","doi-asserted-by":"crossref","first-page":"1336102","DOI":"10.3389\/fphar.2024.1336102","article-title":"JAK\/STAT3 signaling in cardiac fibrosis: a promising therapeutic target","volume":"15","author":"Jiang","year":"2024","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jprot.2024.105287_bb0105","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.755077","article-title":"Magnolol attenuates right ventricular hypertrophy and fibrosis in hypoxia-induced pulmonary arterial hypertensive rats through inhibition of the JAK2\/STAT3 signaling pathway","volume":"12","author":"Fu","year":"2021","journal-title":"Front. Pharmacol."},{"issue":"19","key":"10.1016\/j.jprot.2024.105287_bb0110","doi-asserted-by":"crossref","DOI":"10.3390\/ijms221910431","article-title":"PPAR\u03b3 and TGF\u03b2-major regulators of metabolism, inflammation, and fibrosis in the lungs and kidneys","volume":"22","author":"K\u00f6k\u00e9ny","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.jprot.2024.105287_bb0115","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.stem.2016.10.004","article-title":"Two-way conversion between Lipogenic and myogenic fibroblastic phenotypes Marks the progression and resolution of lung fibrosis","volume":"20","author":"El Agha","year":"2017","journal-title":"Cell Stem Cell"},{"issue":"3","key":"10.1016\/j.jprot.2024.105287_bb0120","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/ki.2010.154","article-title":"A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy","volume":"78","author":"Pang","year":"2010","journal-title":"Kidney Int."},{"issue":"11","key":"10.1016\/j.jprot.2024.105287_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2021.102942","article-title":"The myristoylated alanine-rich C-kinase substrates (MARCKS): a membrane-anchored mediator of the cell function","volume":"20","author":"Chen","year":"2021","journal-title":"Autoimmun. Rev."},{"issue":"12","key":"10.1016\/j.jprot.2024.105287_bb0130","first-page":"14354","article-title":"Tackling MARCKS-PIP3 circuit attenuates fibroblast activation and fibrosis progression, FASEB journal : official publication of the Federation of American Societies for","volume":"33","author":"Yang","year":"2019","journal-title":"Exp. Biol."},{"key":"10.1016\/j.jprot.2024.105287_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellsig.2023.110853","article-title":"Circ-AMOTL1 enhances cardiac fibrosis through binding with EIF4A3 and stabilizing MARCKS expression in diabetic cardiomyopathy","volume":"111","author":"Yang","year":"2023","journal-title":"Cell. Signal."},{"issue":"9","key":"10.1016\/j.jprot.2024.105287_bb0140","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1164\/rccm.201204-0754OC","article-title":"Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigation","volume":"186","author":"Booth","year":"2012","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"4","key":"10.1016\/j.jprot.2024.105287_bb0145","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2017.146","article-title":"miR-146a facilitates osteoarthritis by regulating cartilage homeostasis via targeting Camk2d and Ppp3r2","volume":"8","author":"Zhang","year":"2017","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.jprot.2024.105287_bb0150","article-title":"Regulatory mechanism of CaMKII \u03b4 mediated by RIPK3 on myocardial fibrosis and reversal effects of RIPK3 inhibitor GSK'872","volume":"166","author":"Zhang","year":"2023","journal-title":"Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie"},{"issue":"7","key":"10.1016\/j.jprot.2024.105287_bb0155","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24076549","article-title":"Cadherin-11-Interleukin-6 signaling between cardiac fibroblast and cardiomyocyte promotes ventricular remodeling in a mouse pressure overload-induced heart failure model","volume":"24","author":"Fang","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.jprot.2024.105287_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2023.166933","article-title":"Sfrp2 promotes renal dysfunction of diabetic kidney disease via modulating Fzd5-induced cytosolic calcium ion concentration and CaMKII\/Mek\/Erk pathway in mesangial cells","volume":"1870","author":"Lv","year":"2024","journal-title":"Biochim. Biophys. Acta Mol. basis Dis."},{"issue":"6","key":"10.1016\/j.jprot.2024.105287_bb0165","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1093\/cvr\/cvab109","article-title":"Anxa1 in smooth muscle cells protects against acute aortic dissection","volume":"118","author":"Zhou","year":"2022","journal-title":"Cardiovasc. Res."},{"issue":"1","key":"10.1016\/j.jprot.2024.105287_bb0170","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1186\/s12967-024-05398-y","article-title":"Multiomic analysis of monocyte-derived alveolar macrophages in idiopathic pulmonary fibrosis","volume":"22","author":"Zhang","year":"2024","journal-title":"J. Transl. Med."},{"issue":"2","key":"10.1016\/j.jprot.2024.105287_bb0175","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.intimp.2015.02.012","article-title":"Caffeine protects against alcohol-induced liver fibrosis by dampening the cAMP\/PKA\/CREB pathway in rat hepatic stellate cells","volume":"25","author":"Wang","year":"2015","journal-title":"Int. Immunopharmacol."},{"issue":"14","key":"10.1016\/j.jprot.2024.105287_bb0180","doi-asserted-by":"crossref","first-page":"8248","DOI":"10.1111\/jcmm.15505","article-title":"Asiaticoside might attenuate bleomycin-induced pulmonary fibrosis by activating cAMP and Rap1 signalling pathway assisted by A2AR","volume":"24","author":"Luo","year":"2020","journal-title":"J. Cell. Mol. Med."},{"issue":"7","key":"10.1016\/j.jprot.2024.105287_bb0185","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1089\/ars.2017.7041","article-title":"PDE\/cAMP\/Epac\/C\/EBP-\u03b2 signaling Cascade regulates mitochondria biogenesis of tubular epithelial cells in renal fibrosis","volume":"29","author":"Ding","year":"2018","journal-title":"Antioxid. Redox Signal."},{"issue":"11","key":"10.1016\/j.jprot.2024.105287_bb0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.113414","article-title":"PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis","volume":"42","author":"Jokl","year":"2023","journal-title":"Cell Rep."},{"issue":"1879","key":"10.1016\/j.jprot.2024.105287_bb0195","doi-asserted-by":"crossref","first-page":"20220168","DOI":"10.1098\/rstb.2022.0168","article-title":"Cardiac deficiency of P21-activated kinase 1 promotes atrial arrhythmogenesis in mice following adrenergic challenge","volume":"378","author":"Jung","year":"2023","journal-title":"Philos. Trans. R. Soc. Lond. Ser. B Biol. Sci."},{"issue":"Pt 2","key":"10.1016\/j.jprot.2024.105287_bb0200","article-title":"Involvement of E3 ubiquitin ligase NEDD4-mediated YY1 ubiquitination in alleviating idiopathic pulmonary fibrosis","volume":"269","author":"Chen","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"issue":"3","key":"10.1016\/j.jprot.2024.105287_bb0205","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20190103","article-title":"Transforming growth factor-\u03b2 in tissue fibrosis","volume":"217","author":"Frangogiannis","year":"2020","journal-title":"J. Exp. Med."},{"issue":"25","key":"10.1016\/j.jprot.2024.105287_bb0210","doi-asserted-by":"crossref","first-page":"E4924","DOI":"10.1073\/pnas.1615730114","article-title":"Mitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic lethality in cancer cells","volume":"114","author":"Genini","year":"2017","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"1","key":"10.1016\/j.jprot.2024.105287_bb0215","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1038\/s41467-017-01236-6","article-title":"Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis","volume":"8","author":"Chakraborty","year":"2017","journal-title":"Nat. Commun."},{"issue":"11","key":"10.1016\/j.jprot.2024.105287_bb0220","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1038\/s41419-019-2085-0","article-title":"Inhibition of STAT3 in tubular epithelial cells prevents kidney fibrosis and nephropathy in STZ-induced diabetic mice","volume":"10","author":"Zheng","year":"2019","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.jprot.2024.105287_bb0225","doi-asserted-by":"crossref","DOI":"10.1002\/ardp.202400192","article-title":"Novel therapeutic strategies and drugs for idiopathic pulmonary fibrosis","author":"Shi","year":"2024","journal-title":"Arch. Pharm."},{"issue":"3","key":"10.1016\/j.jprot.2024.105287_bb0230","doi-asserted-by":"crossref","DOI":"10.3390\/molecules29030593","article-title":"STAT3 Decoy Oligodeoxynucleotides Suppress Liver Inflammation and Fibrosis in Liver Cancer Cells and a DDC-Induced Liver Injury Mouse Model","volume":"vol. 29","author":"Choi","year":"2024","journal-title":"Molecules (Basel, Switzerland)"},{"key":"10.1016\/j.jprot.2024.105287_bb0235","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114701","article-title":"Xuanfei Baidu decoction protects against macrophages induced inflammation and pulmonary fibrosis via inhibiting IL-6\/STAT3 signaling pathway","volume":"283","author":"Wang","year":"2022","journal-title":"J. Ethnopharmacol."},{"issue":"1","key":"10.1016\/j.jprot.2024.105287_bb0240","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1038\/s42003-024-05814-5","article-title":"S100A8\/A9 promotes endometrial fibrosis via regulating RAGE\/JAK2\/STAT3 signaling pathway","volume":"7","author":"Xin","year":"2024","journal-title":"Commun. Biol."},{"key":"10.1016\/j.jprot.2024.105287_bb0245","doi-asserted-by":"crossref","first-page":"285","DOI":"10.2147\/DDDT.S191617","article-title":"Endostatin attenuates PDGF-BB- or TGF-\u03b21-induced HSCs activation via suppressing RhoA\/ROCK1 signal pathways","volume":"13","author":"Ren","year":"2019","journal-title":"Drug Des. Devel. Ther."},{"issue":"7","key":"10.1016\/j.jprot.2024.105287_bb0250","doi-asserted-by":"crossref","first-page":"4342","DOI":"10.1021\/acs.jmedchem.2c01753","article-title":"Application and study of ROCK inhibitors in pulmonary fibrosis: recent developments and future perspectives","volume":"66","author":"Xie","year":"2023","journal-title":"J. Med. Chem."},{"issue":"2","key":"10.1016\/j.jprot.2024.105287_bb0255","first-page":"C292","article-title":"LncRNA NEAT1 accelerates renal fibrosis progression via targeting miR-31 and modulating RhoA\/ROCK signal pathway","volume":"324","author":"Chen","year":"2023","journal-title":"Am. J. Phys. Cell Phys."},{"issue":"5","key":"10.1016\/j.jprot.2024.105287_bb0260","doi-asserted-by":"crossref","DOI":"10.1111\/acel.13004","article-title":"Wnt\/\u03b2-catenin\/RAS signaling mediates age-related renal fibrosis and is associated with mitochondrial dysfunction","volume":"18","author":"Miao","year":"2019","journal-title":"Aging Cell"},{"issue":"4","key":"10.1016\/j.jprot.2024.105287_bb0265","doi-asserted-by":"crossref","first-page":"H1767","DOI":"10.1152\/ajpheart.01305.2007","article-title":"Cofilin is a marker of myofibroblast differentiation in cells from porcine aortic cardiac valves, American journal of physiology","volume":"294","author":"Pho","year":"2008","journal-title":"Heart and Circulatory Physiol."},{"issue":"4","key":"10.1016\/j.jprot.2024.105287_bb0270","doi-asserted-by":"crossref","first-page":"345","DOI":"10.2131\/jts.31.345","article-title":"DNA microarray analysis of pulmonary fibrosis three months after exposure to paraquat in rats","volume":"31","author":"Satomi","year":"2006","journal-title":"J. Toxicol. Sci."},{"key":"10.1016\/j.jprot.2024.105287_bb0275","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.bbrc.2021.05.085","article-title":"Cofilin-1 promotes fibrocyte differentiation and contributes to pulmonary fibrosis","volume":"565","author":"Guo","year":"2021","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.jprot.2024.105287_bb0280","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.immuni.2016.01.001","article-title":"Macrophage Akt1 kinase-mediated Mitophagy modulates apoptosis resistance and pulmonary fibrosis","volume":"44","author":"Larson-Casey","year":"2016","journal-title":"Immunity"},{"issue":"4","key":"10.1016\/j.jprot.2024.105287_bb0285","first-page":"C270","article-title":"Exendin-4 induces myocardial protection through MKK3 and Akt-1 in infarcted hearts","volume":"310","author":"Du","year":"2016","journal-title":"Am. J. Phys. Cell Phys."},{"issue":"4","key":"10.1016\/j.jprot.2024.105287_bb0290","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1007\/s10753-023-01825-2","article-title":"Nintedanib ameliorates bleomycin-induced pulmonary fibrosis, inflammation, apoptosis, and oxidative stress by modulating PI3K\/Akt\/mTOR pathway in mice","volume":"46","author":"Pan","year":"2023","journal-title":"Inflammation"},{"issue":"1","key":"10.1016\/j.jprot.2024.105287_bb0295","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s12951-023-01788-4","article-title":"Exosomes derived from human adipose mesenchymal stem cells ameliorate hepatic fibrosis by inhibiting PI3K\/Akt\/mTOR pathway and remodeling choline metabolism","volume":"21","author":"Zhang","year":"2023","journal-title":"J. Nanobiotechnol."},{"issue":"10","key":"10.1016\/j.jprot.2024.105287_bb0300","doi-asserted-by":"crossref","DOI":"10.1111\/jcmm.18381","article-title":"Inhibition of STAT3 by S3I-201 suppress peritoneal fibroblast phenotype conversion and alleviate peritoneal fibrosis","volume":"28","author":"Song","year":"2024","journal-title":"J. Cell. Mol. Med."},{"issue":"18","key":"10.1016\/j.jprot.2024.105287_bb0305","doi-asserted-by":"crossref","first-page":"7391","DOI":"10.1073\/pnas.0609757104","article-title":"Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity","volume":"104","author":"Siddiquee","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"7","key":"10.1016\/j.jprot.2024.105287_bb0310","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1038\/s41401-018-0194-4","article-title":"Magnesium isoglycyrrhizinate ameliorates high fructose-induced liver fibrosis in rat by increasing miR-375-3p to suppress JAK2\/STAT3 pathway and TGF-\u03b21\/Smad signaling","volume":"40","author":"Yang","year":"2019","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.jprot.2024.105287_bb0315","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2023.110589","article-title":"N-methylpiperazine-diepoxyovatodiolide ameliorates peritoneal fibrosis via suppressing TGF-\u03b2\/Smad and JAK\/STAT signaling pathway","volume":"382","author":"Mo","year":"2023","journal-title":"Chem. Biol. Interact."},{"issue":"9","key":"10.1016\/j.jprot.2024.105287_bb0320","doi-asserted-by":"crossref","first-page":"5224","DOI":"10.1111\/jcmm.15175","article-title":"TGF-\u03b2\/Smad and JAK\/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis","volume":"24","author":"Xu","year":"2020","journal-title":"J. Cell. Mol. Med."},{"issue":"10","key":"10.1016\/j.jprot.2024.105287_bb0325","doi-asserted-by":"crossref","first-page":"4302","DOI":"10.1074\/jbc.M116.773085","article-title":"Transforming growth factor-\u03b2 (TGF-\u03b2) directly activates the JAK1-STAT3 Axis to induce hepatic fibrosis in coordination with the SMAD pathway","volume":"292","author":"Tang","year":"2017","journal-title":"J. Biol. Chem."}],"container-title":["Journal of Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391924002197?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391924002197?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,30]],"date-time":"2024-11-30T10:15:01Z","timestamp":1732961701000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1874391924002197"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":65,"alternative-id":["S1874391924002197"],"URL":"https:\/\/doi.org\/10.1016\/j.jprot.2024.105287","relation":{},"ISSN":["1874-3919"],"issn-type":[{"type":"print","value":"1874-3919"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Combining proteomics and Phosphoproteomics to investigate radiation-induced rectal fibrosis in rats and the effects of pSTAT3 inhibitor S3I-201 on human intestinal fibroblasts","name":"articletitle","label":"Article Title"},{"value":"Journal of Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jprot.2024.105287","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105287"}}