{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T22:34:48Z","timestamp":1772922888760,"version":"3.50.1"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100015401","name":"Key Research and Development Projects of Shaanxi Province","doi-asserted-by":"publisher","award":["2023-BSF-322"],"award-info":[{"award-number":["2023-BSF-322"]}],"id":[{"id":"10.13039\/501100015401","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22274130"],"award-info":[{"award-number":["22274130"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Proteomics"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.jprot.2026.105610","type":"journal-article","created":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:40:02Z","timestamp":1769560802000},"page":"105610","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Proteomics analysis of brain tissues of cerebral ischemic rat treated with Xingnaojing injection and its brain component muscone"],"prefix":"10.1016","volume":"326","author":[{"given":"Chunli","family":"Gao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han","family":"Hao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xufei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niuniu","family":"Mao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juanjuan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanfeng","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nan","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pu","family":"Jia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohui","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sha","family":"Liao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yangyang","family":"Bian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jprot.2026.105610_bb0005","doi-asserted-by":"crossref","first-page":"7147","DOI":"10.1038\/s41467-023-43070-z","article-title":"Pathogenesis-adaptive polydopamine nanosystem for sequential therapy of ischemic stroke","volume":"14","author":"Wu","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.jprot.2026.105610_bb0010","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.678744","article-title":"Immune cells in the BBB disruption after acute ischemic stroke: targets for immune therapy?","volume":"12","author":"Qiu","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jprot.2026.105610_bb0015","article-title":"Preclinical evidence and mechanism of Xingnaojing injection for cerebral ischemia: a systematic review and meta-analysis of animal studies, Evid. Based Complement","volume":"2018","author":"Ma","year":"2018","journal-title":"Altern. Med."},{"issue":"8","key":"10.1016\/j.jprot.2026.105610_bb0020","doi-asserted-by":"crossref","first-page":"e93","DOI":"10.1161\/CIR.0000000000001123","article-title":"Heart disease and stroke statistics-2023 update: a report from the American Heart Association","volume":"147","author":"Tsao","year":"2023","journal-title":"Circulation"},{"key":"10.1016\/j.jprot.2026.105610_bb0025","article-title":"Proteomic assessment of iTRAQ-based NaoMaiTong in the treatment of ischemic stroke in rats, Evid. Based Complement","volume":"2019","author":"Li","year":"2019","journal-title":"Altern. Med."},{"issue":"8","key":"10.1016\/j.jprot.2026.105610_bb0030","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.2271","article-title":"QKI 6 ameliorates CIRI through promoting synthesis of triglyceride in neuron and inhibiting neuronal apoptosis associated with SIRT1-PPAR\u03b3-PGC-1\u03b1 axis","volume":"11","author":"Liu","year":"2021","journal-title":"Brain Behav."},{"issue":"9","key":"10.1016\/j.jprot.2026.105610_bb0035","doi-asserted-by":"crossref","first-page":"2742","DOI":"10.1161\/STROKEAHA.120.030895","article-title":"Cortical microinfarcts associated with worse outcomes in patients with acute ischemic stroke receiving endovascular treatment","volume":"51","author":"Wei","year":"2020","journal-title":"Stroke"},{"issue":"3","key":"10.1016\/j.jprot.2026.105610_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e25267","article-title":"Xingnaojing injection alleviates cerebral ischemia\/reperfusion injury through regulating endoplasmic reticulum stress in vivo and in vitro","volume":"10","author":"Dong","year":"2024","journal-title":"Heliyon"},{"issue":"1090\u20132430 (Electronic)","key":"10.1016\/j.jprot.2026.105610_bb0045","article-title":"Muscone alleviates neuronal injury via increasing stress granules formation and reducing apoptosis in acute ischemic stroke","volume":"373","author":"Sun","year":"2024","journal-title":"Exp. Neurol."},{"issue":"7","key":"10.1016\/j.jprot.2026.105610_bb0050","first-page":"498","article-title":"XingNaoJing injections protect against cerebral ischemia\/reperfusion injury and alleviate blood-brain barrier disruption in rats, through an underlying mechanism of NLRP3 inflammasomes suppression","volume":"17","author":"Qu","year":"2019","journal-title":"Chin. J. Nat. Med."},{"key":"10.1016\/j.jprot.2026.105610_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115836","article-title":"Protective effect of Xingnaojing injection on ferroptosis after cerebral ischemia injury in MCAO rats and SH-SY5Y cells","volume":"301","author":"Liu","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jprot.2026.105610_bb0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2023.154696","article-title":"Herb-drug interaction of Xingnaojing injection and Edaravone via pharmacokinetics, mixed inhibition of UGTs, and molecular docking","volume":"112","author":"Qi","year":"2023","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jprot.2026.105610_bb0065","article-title":"Trial of a prehospital intervention with traditional Chinese medicine for acute stroke (TRACE): protocol for a mixed-methods research study","volume":"13","author":"Chen","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.jprot.2026.105610_bb0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2024.124830","article-title":"Nasal administration of Xingnaojing biomimetic nanoparticles for the treatment of ischemic stroke","volume":"666","author":"Li","year":"2024","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.jprot.2026.105610_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115475","article-title":"Proteomics on the role of muscone in the \"consciousness-restoring resuscitation\" effect of musk on ischemic stroke","volume":"296","author":"Han","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jprot.2026.105610_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116287","article-title":"Protective effect and underlying mechanism of muscone on acute cerebral ischemia-reperfusion injury in rats","volume":"308","author":"Zhang","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jprot.2026.105610_bb0085","series-title":"Moschus, Pharmacopoeia of the People\u2019s Republic of China","author":"Chinese Pharmacopoeia Commission","year":"2020"},{"issue":"11","key":"10.1016\/j.jprot.2026.105610_bb0090","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1111\/jphp.13157","article-title":"Muscone ameliorates diabetic peripheral neuropathy through activating AKT\/mTOR signalling pathway","volume":"71","author":"Dong","year":"2019","journal-title":"J. Pharm. Pharmacol."},{"issue":"8","key":"10.1016\/j.jprot.2026.105610_bb0095","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1007\/s10571-015-0204-8","article-title":"Effects of muscone on the expression of P-gp, MMP-9 on blood-brain barrier model in vitro","volume":"35","author":"Wang","year":"2015","journal-title":"Cell. Mol. Neurobiol."},{"issue":"10","key":"10.1016\/j.jprot.2026.105610_bb0100","doi-asserted-by":"crossref","first-page":"4308","DOI":"10.7150\/thno.41322","article-title":"Muscone\/RI7217 co-modified upward messenger DTX liposomes enhanced permeability of blood-brain barrier and targeting glioma","volume":"10","author":"Kang","year":"2020","journal-title":"Theranostics"},{"issue":"3","key":"10.1016\/j.jprot.2026.105610_bb0105","first-page":"808","article-title":"Anti-cerebral ischemia mechanisms of brain absorption components of Xingnaojing injection based on GC-MS and network pharmacology","volume":"52","author":"Wu","year":"2021","journal-title":"Chin. Tradit. Herb. Drug"},{"issue":"8","key":"10.1016\/j.jprot.2026.105610_bb0110","article-title":"Muscone and (+)-borneol cooperatively strengthen CREB induction of claudin 5 in IL-1\u03b2-induced endothelium injury","volume":"11","author":"Li","year":"2022","journal-title":"Antioxidants (Basel)"},{"key":"10.1016\/j.jprot.2026.105610_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellimm.2023.104704","article-title":"Muscone promotes functional recovery by facilitating microglia polarization into M2 phenotype through PPAR-\u03b3 pathway after ischemic stroke","volume":"386","author":"Liu","year":"2023","journal-title":"Cell. Immunol."},{"issue":"7","key":"10.1016\/j.jprot.2026.105610_bb0120","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20071661","article-title":"IMM-H004 protects against cerebral ischemia injury and cardiopulmonary complications via CKLF1 mediated inflammation pathway in adult and aged rats","volume":"20","author":"Ai","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jprot.2026.105610_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154111","article-title":"Ligustilide ameliorates hippocampal neuronal injury after cerebral ischemia reperfusion through activating PINK1\/parkin-dependent mitophagy","volume":"101","author":"Mao","year":"2022","journal-title":"Phytomedicine"},{"issue":"11","key":"10.1016\/j.jprot.2026.105610_bb0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2021.166230","article-title":"Orexin-a alleviates astrocytic apoptosis and inflammation via inhibiting OX1R-mediated NF-\u03baB and MAPK signaling pathways in cerebral ischemia\/reperfusion injury","volume":"1867","author":"Xu","year":"2021","journal-title":"Biochim. Biophys. Acta Mol. basis Dis."},{"key":"10.1016\/j.jprot.2026.105610_bb0135","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.3389\/fimmu.2019.02408","article-title":"Pterostilbene attenuates astrocytic inflammation and neuronal oxidative injury after ischemia-reperfusion by inhibiting NF-\u03baB phosphorylation","volume":"10","author":"Liu","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.jprot.2026.105610_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2021.153673","article-title":"Thymus quinquecostatus Celak. Ameliorates cerebral ischemia-reperfusion injury via dual antioxidant actions: activating Keap1\/Nrf2\/HO-1 signaling pathway and directly scavenging ROS","volume":"91","author":"Fan","year":"2021","journal-title":"Phytomedicine"},{"issue":"5","key":"10.1016\/j.jprot.2026.105610_bb0145","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1203\/00006450-199711000-00021","article-title":"Sensorimotor function and neuropathology five to six weeks after hypoxia-ischemia in seven-day-old rats","volume":"42","author":"Bona","year":"1997","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.jprot.2026.105610_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2024.114726","article-title":"BMSC-exosomes attenuate ALP dysfunction by restoring lysosomal function via the mTOR\/TFEB Axis to reduce cerebral ischemia-reperfusion injury","volume":"376","author":"Liu","year":"2024","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.jprot.2026.105610_bb0155","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.cbi.2019.06.008","article-title":"Sevoflurane prevents miR-181a-induced cerebral ischemia\/reperfusion injury","volume":"308","author":"Zhang","year":"2019","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.jprot.2026.105610_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2023.114385","article-title":"Chaihu-Shugan-San inhibits neuroinflammation in the treatment of post-stroke depression through the JAK\/STAT3-GSK3\u03b2\/PTEN\/Akt pathway","volume":"160","author":"Fan","year":"2023","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.jprot.2026.105610_bb0165","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/s41592-019-0638-x","article-title":"DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput","volume":"17","author":"Demichev","year":"2020","journal-title":"Nat. Methods"},{"issue":"3","key":"10.1016\/j.jprot.2026.105610_bb0170","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1080\/10618600.1996.10474713","article-title":"R: a language for data analysis and graphics","volume":"5","author":"Ihaka","year":"1996","journal-title":"J. Comput. Graph. Stat."},{"issue":"1","key":"10.1016\/j.jprot.2026.105610_bb0175","doi-asserted-by":"crossref","first-page":"3813","DOI":"10.1038\/s41598-021-82352-8","article-title":"Exercise alters the mitochondrial proteostasis and induces the mitonuclear imbalance and UPR(mt) in the hypothalamus of mice","volume":"11","author":"Braga","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jprot.2026.105610_bb0180","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.mito.2014.06.003","article-title":"Mitochondrial encephalomyopathy with cytochrome c oxidase deficiency caused by a novel mutation in the MTCO1 gene","volume":"17","author":"Debray","year":"2014","journal-title":"Mitochondrion"},{"issue":"1","key":"10.1016\/j.jprot.2026.105610_bb0185","first-page":"50","article-title":"Analysis of mitochondrial ND1 gene in human colorectal cancer","volume":"16","author":"Akouchekian","year":"2011","journal-title":"J. Res. Med. Sci."},{"issue":"8","key":"10.1016\/j.jprot.2026.105610_bb0190","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0042242","article-title":"Rare primary mitochondrial DNA mutations and probable synergistic variants in Leber\u2019s hereditary optic neuropathy","volume":"7","author":"Achilli","year":"2012","journal-title":"PloS One"},{"issue":"5","key":"10.1016\/j.jprot.2026.105610_bb0195","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1007\/s12185-017-2287-0","article-title":"Screening novel autoantigens targeted by serum IgG autoantibodies in immunorelated pancytopenia by SEREX","volume":"106","author":"Hao","year":"2017","journal-title":"Int. J. Hematol."},{"issue":"11","key":"10.1016\/j.jprot.2026.105610_bb0200","doi-asserted-by":"crossref","first-page":"4196","DOI":"10.1172\/JCI81260","article-title":"Additive loss-of-function proteasome subunit mutations in CANDLE\/PRAAS patients promote type I IFN production","volume":"125","author":"Brehm","year":"2015","journal-title":"J. Clin. Invest."},{"issue":"2","key":"10.1016\/j.jprot.2026.105610_bb0205","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1159\/000487174","article-title":"Interference with PSMB4 expression exerts an anti-tumor effect by decreasing the invasion and proliferation of human glioblastoma cells","volume":"45","author":"Cheng","year":"2018","journal-title":"Cell. Physiol. Biochem."},{"issue":"10","key":"10.1016\/j.jprot.2026.105610_bb0210","doi-asserted-by":"crossref","first-page":"4674","DOI":"10.1097\/MS9.0000000000001210","article-title":"Artificial intelligence-based prediction of molecular and genetic markers for hepatitis C-related hepatocellular carcinoma","volume":"85","author":"Colak","year":"2023","journal-title":"Ann. Med. Surg."},{"issue":"1","key":"10.1016\/j.jprot.2026.105610_bb0215","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1038\/jcbfm.2011.120","article-title":"Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge","volume":"32","author":"James","year":"2012","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"8","key":"10.1016\/j.jprot.2026.105610_bb0220","doi-asserted-by":"crossref","first-page":"646","DOI":"10.7150\/jca.9955","article-title":"Gene expression analysis of the 26S proteasome subunit PSMB4 reveals significant upregulation, different expression and association with proliferation in human pulmonary neuroendocrine tumours","volume":"5","author":"Mairinger","year":"2014","journal-title":"J. Cancer"},{"key":"10.1016\/j.jprot.2026.105610_bb0225","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116507","article-title":"Network pharmacology-based prediction and validation of the active ingredients and potential mechanisms of the Huangxiong formula for treating ischemic stroke","volume":"312","author":"Zhao","year":"2023","journal-title":"J. Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.jprot.2026.105610_bb0230","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/jog.15834","article-title":"Data-independent acquisition for proteomic applications in early-stage endometrial cancer progression","volume":"50","author":"Cheng","year":"2024","journal-title":"J. Obstet. Gynaecol. Res."},{"issue":"2","key":"10.1016\/j.jprot.2026.105610_bb0235","doi-asserted-by":"crossref","first-page":"159","DOI":"10.4155\/fmc.14.152","article-title":"Photoaffinity labeling in target- and binding-site identification","volume":"7","author":"Smith","year":"2015","journal-title":"Future Med. Chem."},{"issue":"5971","key":"10.1016\/j.jprot.2026.105610_bb0240","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1126\/science.1177319","article-title":"Identification of a primary target of thalidomide teratogenicity","volume":"327","author":"Ito","year":"2010","journal-title":"Science"},{"issue":"11","key":"10.1016\/j.jprot.2026.105610_bb0245","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1038\/nprot.2017.100","article-title":"Measuring protein structural changes on a proteome-wide scale using limited proteolysis-coupled mass spectrometry","volume":"12","author":"Schopper","year":"2017","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.jprot.2026.105610_bb0250","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1038\/nprot.2015.101","article-title":"Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry","volume":"10","author":"Franken","year":"2015","journal-title":"Nat. Protoc."},{"issue":"12","key":"10.1016\/j.jprot.2026.105610_bb0255","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1038\/s41589-023-01355-w","article-title":"Chemoproteomic mapping of the glycolytic targetome in cancer cells","volume":"19","author":"Tian","year":"2023","journal-title":"Nat. Chem. Biol."},{"issue":"7","key":"10.1016\/j.jprot.2026.105610_bb0260","doi-asserted-by":"crossref","first-page":"3352","DOI":"10.1021\/acs.analchem.1c05455","article-title":"Proteome-wide deconvolution of drug targets and binding sites by lysine reactivity profiling","volume":"94","author":"Ruan","year":"2022","journal-title":"Anal. Chem."},{"issue":"15\u201316","key":"10.1016\/j.jprot.2026.105610_bb0265","article-title":"A simplified thermal proteome profiling approach to screen protein targets of a ligand","volume":"20","author":"Zhang","year":"2020","journal-title":"Proteomics"},{"issue":"7","key":"10.1016\/j.jprot.2026.105610_bb0270","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1080\/15548627.2021.1997051","article-title":"ALDOA maintains NLRP3 inflammasome activation by controlling AMPK activation","volume":"18","author":"Bai","year":"2022","journal-title":"Autophagy"},{"issue":"2","key":"10.1016\/j.jprot.2026.105610_bb0275","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1093\/ndt\/gft415","article-title":"Intra-renal transfection of heat shock protein 90 alpha or beta (Hsp90\u03b1 or Hsp90\u03b2) protects against ischemia\/reperfusion injury","volume":"29","author":"Barrera-Chimal","year":"2014","journal-title":"Nephrol. Dial. Transplant."},{"issue":"2","key":"10.1016\/j.jprot.2026.105610_bb0280","doi-asserted-by":"crossref","DOI":"10.3390\/genes14020355","article-title":"HSP70 expression signature in renal cell carcinoma: a clinical and bioinformatic analysis approach","volume":"14","author":"Abd El-Fadeal","year":"2023","journal-title":"Genes (Basel)"},{"issue":"6","key":"10.1016\/j.jprot.2026.105610_bb0285","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1080\/13813455.2024.2323947","article-title":"Isorhamnetin as a potential therapeutic agent for diabetes mellitus through PGK1\/AKT activation","volume":"130","author":"Alqudah","year":"2024","journal-title":"Arch. Physiol. Biochem."},{"key":"10.1016\/j.jprot.2026.105610_bb0290","doi-asserted-by":"crossref","DOI":"10.1016\/j.gene.2021.145897","article-title":"PGAM1 regulates the glycolytic metabolism of SCs in tibetan sheep and its influence on the development of SCs","volume":"804","author":"An","year":"2021","journal-title":"Gene"},{"issue":"9","key":"10.1016\/j.jprot.2026.105610_bb0295","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1071\/FP05312","article-title":"Novel interaction of selenium-binding protein with glyceraldehyde-3-phosphate dehydrogenase and fructose-bisphosphate aldolase of Arabidopsis thaliana","volume":"33","author":"Agalou","year":"2006","journal-title":"Funct. Plant Biol."},{"issue":"9","key":"10.1016\/j.jprot.2026.105610_bb0300","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1080\/02699052.2017.1357836","article-title":"Biofluid biomarkers of traumatic brain injury","volume":"31","author":"Agoston","year":"2017","journal-title":"Brain Inj."},{"issue":"1","key":"10.1016\/j.jprot.2026.105610_bb0305","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.yexcr.2012.09.003","article-title":"Valosin containing protein (VCP\/p97) is a novel substrate for the protein tyrosine phosphatase PTPL1","volume":"319","author":"Abaan","year":"2013","journal-title":"Exp. Cell Res."},{"issue":"1","key":"10.1016\/j.jprot.2026.105610_bb0310","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-48196-z","article-title":"Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice","volume":"9","author":"Burmistrova","year":"2019","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.jprot.2026.105610_bb0315","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s12276-019-0229-z","article-title":"Connectivity map identifies luteolin as a treatment option of ischemic stroke by inhibiting MMP9 and activation of the PI3K\/Akt signaling pathway","volume":"51","author":"Luo","year":"2019","journal-title":"Exp. Mol. Med."},{"issue":"1","key":"10.1016\/j.jprot.2026.105610_bb0320","article-title":"Integrated analysis of weighted gene coexpression network analysis identifying six genes as novel biomarkers for Alzheimer\u2019s disease","volume":"2021","author":"Zhang","year":"2021","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"1","key":"10.1016\/j.jprot.2026.105610_bb0325","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1038\/s41392-024-01839-8","article-title":"Mitochondrial dysfunction: mechanisms and advances in therapy","volume":"9","author":"Zong","year":"2024","journal-title":"Signal Transduct. Target. Ther."},{"issue":"32","key":"10.1016\/j.jprot.2026.105610_bb0330","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202303584","article-title":"Scutellarin rescued mitochondrial damage through ameliorating mitochondrial glucose oxidation via the Pdk-Pdc axis","volume":"10","author":"Sheng","year":"2023","journal-title":"Adv. Sci."}],"container-title":["Journal of Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391926000138?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874391926000138?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T03:50:04Z","timestamp":1772855404000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1874391926000138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":66,"alternative-id":["S1874391926000138"],"URL":"https:\/\/doi.org\/10.1016\/j.jprot.2026.105610","relation":{},"ISSN":["1874-3919"],"issn-type":[{"value":"1874-3919","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Proteomics analysis of brain tissues of cerebral ischemic rat treated with Xingnaojing injection and its brain component muscone","name":"articletitle","label":"Article Title"},{"value":"Journal of Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jprot.2026.105610","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105610"}}