{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:14:06Z","timestamp":1758478446370},"reference-count":46,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Psychiatric Research"],"published-print":{"date-parts":[[2007,11]]},"DOI":"10.1016\/j.jpsychires.2006.07.003","type":"journal-article","created":{"date-parts":[[2006,9,2]],"date-time":"2006-09-02T07:22:19Z","timestamp":1157181739000},"page":"885-892","source":"Crossref","is-referenced-by-count":6,"title":["M129V variation in the prion protein gene and psychotic disorders: Relationship to neuropsychological and psychopathological measures"],"prefix":"10.1016","volume":"41","author":[{"given":"Lourdes","family":"Martorell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joaqu\u00edn","family":"Valero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bego\u00f1a","family":"Mulet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfonso","family":"Guti\u00e9rrez-Zotes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ma Jos\u00e9","family":"Cort\u00e9s","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manel","family":"Jariod","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Modesto","family":"P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Labad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabet","family":"Vilella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpsychires.2006.07.003_bib1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.trim.2005.03.015","article-title":"Strategies in analysis of the genetic component of multifactorial diseases; biostatistical aspects","volume":"14","author":"Barnetche","year":"2005","journal-title":"Transplant Immunology"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib2","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1097\/00005053-199803000-00003","article-title":"Obsessions and compulsions as a distinct cluster of symptoms in schizophrenia: a neuropsychological study","volume":"186","author":"Berman","year":"1998","journal-title":"Journal of Nervous and Mental Disease"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib3","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1212\/WNL.51.3.734","article-title":"Polymorphism of the prion protein is associated with cognitive impairment in the elderly: the EVA study","volume":"51","author":"Berr","year":"1998","journal-title":"Neurology"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib4","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1038\/37733","article-title":"The cellular prion protein binds copper in vivo","volume":"390","author":"Brown","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib5","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1006\/exnr.1997.6505","article-title":"Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity","volume":"146","author":"Brown","year":"1997","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib6","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1212\/WNL.55.4.593","article-title":"Polymorphism at codon 129 of the prion protein gene is not associated with sporadic AD","volume":"55","author":"Combarros","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib7","series-title":"The continuous performance test (CPT)","author":"Connors","year":"1995"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib8","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.nbd.2005.01.001","article-title":"Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons","volume":"19","author":"Criado","year":"2005","journal-title":"Neurobiology of Disease"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib9","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1002\/ana.10658","article-title":"Early cognitive decline is associated with prion protein codon 129 polymorphism","volume":"54","author":"Croes","year":"2003","journal-title":"Annals of Neurology"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib10","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1001\/archpsyc.60.5.443","article-title":"White matter changes in schizophrenia: evidence for myelin-related dysfunction","volume":"60","author":"Davis","year":"2003","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib11","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1007\/s00415-003-1057-5","article-title":"The 129 codon polymorphism of the prion protein gene influences earlier cognitive performance in Down syndrome subjects","volume":"250","author":"Del Bo","year":"2003","journal-title":"Journal of Neurology"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib12","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1002\/ana.10507","article-title":"PRNP Val129 homozygosity increases risk for early-onset Alzheimer\u2019s disease","volume":"53","author":"Dermaut","year":"2003","journal-title":"Annals of Neurology"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib13","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1212\/01.WNL.0000103290.74549.DC","article-title":"Polymorphisms within the prion (PrP) and prion-like protein (Doppel) genes in AD","volume":"62","author":"Golanska","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib14","unstructured":"Goldberg DP, Williams, P. A user\u2019s Guide to the GHQ. NFER-Nelson, Windsor, 1988."},{"key":"10.1016\/j.jpsychires.2006.07.003_bib15","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1348\/014466501163607","article-title":"Processing of threat-related affect is delayed in delusion-prone individuals","volume":"40","author":"Green","year":"2001","journal-title":"British Journal of Clinical Psychology"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib16","series-title":"Wisconsin card sorting test manual","author":"Heaton","year":"1993"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib17","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1001\/archpsyc.1994.03950060033003","article-title":"Neuropsychological deficits in schizophrenics. Relationship to age, chronicity, and dementia","volume":"51","author":"Heaton","year":"1994","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib18","doi-asserted-by":"crossref","first-page":"8866","DOI":"10.1523\/JNEUROSCI.19-20-08866.1999","article-title":"Evidence of presynaptic localization and function of the prion protein","volume":"19","author":"Herms","year":"1999","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib19","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1176\/ajp.149.7.898","article-title":"Neuropsychological functioning of first-episode schizophreniform patients","volume":"149","author":"Hoff","year":"1992","journal-title":"American Journal of Psychiatry"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib20","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/0001-6918(66)90004-7","article-title":"The Stroop color-word test: a review","volume":"25","author":"Jensen","year":"1966","journal-title":"Acta Psychologica"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib21","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.biopsych.2005.09.021","article-title":"Fornix integrity and hippocampal volume in male schizophrenic patients","volume":"60","author":"Kuroki","year":"2006","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib22","series-title":"Neuropsychological assessment","author":"Lezak","year":"1997"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib23","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1017\/S0033291700002579","article-title":"Validity of the scaled version of the General Health Questionnaire (GHQ-28) in a Spanish population","volume":"16","author":"Lobo","year":"1986","journal-title":"Psychological Medicine"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib24","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1590\/S0100-879X2001000500005","article-title":"Insights into the physiological function of cellular prion protein","volume":"34","author":"Martins","year":"2001","journal-title":"Brazilian Journal of Medical and Biological Research"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib25","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1034\/j.1600-0404.2003.00199.x","article-title":"The normal population distribution of PRNP codon 129 polymorphism","volume":"108","author":"Nurmi","year":"2003","journal-title":"Acta Neurologica Scandinavica"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib26","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1002\/ana.10748","article-title":"Absence of association between codon 129\/219 polymorphisms of the prion protein gene and Alzheimer\u2019s disease in Japan","volume":"54","author":"Ohkubo","year":"2003","journal-title":"Annals of Neurology"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib27","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0028-3932(71)90067-4","article-title":"The assessment and analysis of handedness: the Edinburgh Inventory","volume":"9","author":"Oldfield","year":"1971","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib28","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1038\/352340a0","article-title":"Homozygous prion protein genotype predisposes to sporadic Creutzfeldt-Jakob disease","volume":"352","author":"Palmer","year":"1991","journal-title":"Nature"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib29","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1093\/hmg\/ddi228","article-title":"The prion gene is associated with human long-term memory","volume":"14","author":"Papassotiropoulos","year":"2005","journal-title":"Human Molecular Genetics"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib30","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1017\/S135561770000014X","article-title":"The nature of learning and memory impairments in schizophrenia","volume":"1","author":"Paulsen","year":"1995","journal-title":"Journal of International Neuropsychological Society"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib31","first-page":"171","article-title":"Validaci\u00f3n de la escala de los s\u00edndromes positivo y negativo (PANSS) en una muestra de esquizofr\u00e9nicos espa\u00f1oles","volume":"22","author":"Peralta","year":"1994","journal-title":"Actas Luso-Espa\u00f1olas de Neurolog\u00eda y Psiquiatr\u00eda"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib32","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.gene.2004.11.049","article-title":"The prion protein gene: identifying regulatory signals using marsupial sequence","volume":"349","author":"Premzl","year":"2005","journal-title":"Gene"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib33","doi-asserted-by":"crossref","first-page":"271","DOI":"10.2466\/pms.1958.8.3.271","article-title":"Validity of the trail making test as an indicator of organic brain damage","volume":"8","author":"Reitan","year":"1958","journal-title":"Perceptual and Motor Skills"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib34","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1212\/01.WNL.0000130198.72589.69","article-title":"Prion protein codon 129 polymorphism and risk of Alzheimer disease","volume":"63","author":"Riemenschneider","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib35","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1006\/nimg.2001.0932","article-title":"Methionine homozygosity at codon 129 in the prion protein is associated with white matter reduction and enlargement of CSF compartments in healthy volunteers and schizophrenic patients","volume":"15","author":"Rujescu","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib36","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0920-9964(02)00343-2","article-title":"Association study of a SNP coding for a M129V substitution in the prion protein in schizophrenia","volume":"62","author":"Rujescu","year":"2003","journal-title":"Schizophrenia Research"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib37","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1038\/sj.mp.4001327","article-title":"M129V variation in the prion protein may influence cognitive performance","volume":"8","author":"Rujescu","year":"2003","journal-title":"Molecular Psychiatry"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib38","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1001\/archpsyc.1994.03950020048005","article-title":"Neuropsychological deficits in neuroleptic naive patients with first-episode schizophrenia","volume":"51","author":"Saykin","year":"1994","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib39","doi-asserted-by":"crossref","first-page":"13326","DOI":"10.1073\/pnas.2235648100","article-title":"NADPH oxidase and extracellular regulated kinases 1\/2 are targets of prion protein signaling in neuronal and nonneuronal cells","volume":"100","author":"Schneider","year":"2003","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib40","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1037\/h0054651","article-title":"Studies of interference in serial verbal reactions","volume":"18","author":"Stroop","year":"1935","journal-title":"Journal of Experimental Psychology"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib41","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/sj.mp.4000790","article-title":"Lack of evidence to support the association of the human prion gene with schizophrenia","volume":"6","author":"Tsai","year":"2001","journal-title":"Molecular Psychiatry"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib42","first-page":"109","article-title":"Development and verification of the Spanish version of the \u201cscanning system\u201d psychiatric interview (\u201cQuestionnaires for clinical evaluation in neuropsychiatry\u201d)","volume":"22","author":"Vazquez-Barquero","year":"1994","journal-title":"Actas Luso Espanolas de Neurologia Psiquiatria y Ciencias Afines"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib43","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1126\/science.1103932","article-title":"Human prion protein with valine 129 prevents expression of variant CJD phenotype","volume":"306","author":"Wadsworth","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib44","series-title":"Wechsler memory scale-revised","author":"Wechsler","year":"1987"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib45","series-title":"Wechsler adult intelligence scale","author":"Wechsler","year":"1997"},{"key":"10.1016\/j.jpsychires.2006.07.003_bib46","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1001\/archpsyc.1990.01810180089012","article-title":"SCAN. Schedules for Clinical Assessment in Neuropsychiatry","volume":"47","author":"Wing","year":"1990","journal-title":"Archives of General Psychiatry"}],"container-title":["Journal of Psychiatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395606001294?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395606001294?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,20]],"date-time":"2019-04-20T21:15:36Z","timestamp":1555794936000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022395606001294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11]]},"references-count":46,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["S0022395606001294"],"URL":"https:\/\/doi.org\/10.1016\/j.jpsychires.2006.07.003","relation":{},"ISSN":["0022-3956"],"issn-type":[{"value":"0022-3956","type":"print"}],"subject":[],"published":{"date-parts":[[2007,11]]}}}