{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T03:53:37Z","timestamp":1784951617721,"version":"3.55.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Psychiatric Research"],"published-print":{"date-parts":[[2007,9]]},"DOI":"10.1016\/j.jpsychires.2006.07.013","type":"journal-article","created":{"date-parts":[[2006,9,8]],"date-time":"2006-09-08T19:25:10Z","timestamp":1157743510000},"page":"523-529","source":"Crossref","is-referenced-by-count":257,"title":["Serum S100B and antioxidant enzymes in bipolar patients"],"prefix":"10.1016","volume":"41","author":[{"given":"Ana Cristina","family":"Andreazza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carina","family":"Cassini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriane Ribeiro","family":"Rosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina Concli","family":"Leite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia M.V.","family":"de Almeida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u0131\u00b4cia","family":"Nardin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo B.N.","family":"Cunha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keila Maria","family":"Ceres\u00e9r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aida","family":"Santin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmem","family":"Gottfried","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirian","family":"Salvador","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio","family":"Kapczinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Alberto","family":"Gon\u00e7alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpsychires.2006.07.013_bib1","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1056\/NEJMra035354","article-title":"Medical progress: bipolar disorder","volume":"351","author":"Belmaker","year":"2004","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib2","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/S0076-6879(55)02300-8","article-title":"Assay of catalases and peroxidases","volume":"2","author":"Chance","year":"1954","journal-title":"Methods in Enzymology"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib3","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1615\/CritRevNeurobiol.v16.i12.90","article-title":"Neuroprotective and neurotrophic actions of the mood stabilizer lithium: can it be used to treat neurodegenerative diseases?","volume":"16","author":"Chuang","year":"2004","journal-title":"Critical Reviews in Neurobiology"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib4","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.neulet.2003.09.062","article-title":"Target evaluation processing and serum levels of nerve tissue protein S100B in patients with remitted major depression","volume":"354","author":"Dietrich","year":"2004","journal-title":"Neuroscience Letter"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib5","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/S1357-2725(01)00046-2","article-title":"S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles","volume":"33","author":"Donato","year":"2001","journal-title":"International Journal of Biochemistry and Cell Biology"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib6","series-title":"Structured clinical interview for DSM-IV (SCID-I)","author":"First","year":"1998"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib7","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1046\/j.1525-1373.1999.d01-140.x","article-title":"Antioxidants, oxidative stress, and degenerative neurological disorders","volume":"222","author":"Floyd","year":"1999","journal-title":"Proceedings of the Society for Experimental Biology and Medicine"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib8","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1002\/jnr.10511","article-title":"Lithium inhibits Abeta-induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation","volume":"71","author":"Ghribi","year":"2003","journal-title":"Journal of Neuroscience Research"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib9","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"Journal of Neurology Neurosurgery and Psychiatry"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib10","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s00213-004-1999-z","article-title":"The astroglial protein S100B and visually evoked event-related potentials before and after antidepressant treatment","volume":"178","author":"Hetzel","year":"2005","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib11","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.mam.2005.07.006","article-title":"Superoxide dismutases and their impact upon human health","volume":"26","author":"Johnson","year":"2005","journal-title":"Molecular Aspects of Medicine"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib12","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1038\/sj.mp.4000696","article-title":"Disease-specific alterations in frontal cortex brain proteins in schizophrenia, bipolar disorder, and major depressive disorder. The Stanley Neuropathology Consortium","volume":"5","author":"Johnston-Wilson","year":"2000","journal-title":"Molecular Psychiatry"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib13","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/cbf.940","article-title":"Lipid peroxidation and antioxidant enzyme levels in patients with schizophrenia and bipolar desorder","volume":"20","author":"Kuloglu","year":"2002","journal-title":"Cell Biochemistry and Function"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib14","doi-asserted-by":"crossref","first-page":"2528","DOI":"10.1001\/jama.293.20.2528","article-title":"The increasing medical burden in bipolar disorder","volume":"293","author":"Kupfer","year":"2005","journal-title":"Journal of the American Medical Association"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib15","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.ejphar.2006.03.076","article-title":"Cytoprotection by lithium and valproate varies between cell types and cellular stresses","volume":"539","author":"Lai","year":"2006","journal-title":"European Journal of Pharmacology"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib16","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0022-3956(01)00003-6","article-title":"Increased serum S100B protein in schizophrenia: a study in medication-free patients","volume":"35","author":"Lara","year":"2001","journal-title":"Journal of Psychiatry Research"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib17","unstructured":"Machado-Vieira R. Avalia\u00e7\u00e3o neuroqu\u0131\u00b4mica de altera\u00e7\u00f5es tr\u00f3ficas e\/ou dano neur\u00f4nio \u2013 glial durante epis\u00f3dios man\u0131\u00b4acos. PhD Thesis. University of S\u00e3o Paulo; 2005."},{"key":"10.1016\/j.jpsychires.2006.07.013_bib18","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0924-977X(02)00029-9","article-title":"Elevated serum S100B protein in drug-free bipolar patients during first manic episode: a pilot study","volume":"12","author":"Machado-Vieira","year":"2002","journal-title":"European Neuropsychopharmacology"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib19","first-page":"3170","article-title":"The role of superoxide anion in the antioxidation of epinephrine and a simple assay for superoxide dismutase","volume":"217","author":"Mirsa","year":"1972","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib20","first-page":"377","article-title":"The utility of DALYs for public health policy and research: a reply","volume":"75","author":"Murray","year":"1997","journal-title":"Bulletin of the World Health Organization"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib21","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.clinbiochem.2004.12.014","article-title":"Ontogenetic changes in serum S100B in Down syndrome patients","volume":"38","author":"Netto","year":"2005","journal-title":"Clinical Biochemistry"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib22","doi-asserted-by":"crossref","first-page":"13290","DOI":"10.1073\/pnas.95.22.13290","article-title":"Glial reduction in the subgenual prefrontal cortex in mood disorders","volume":"95","author":"Ongur","year":"1998","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib23","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1097\/00004850-200403000-00006","article-title":"Antioxidant enzyme activities and oxidative stress in affective disorders","volume":"19","author":"Ozcan","year":"2004","journal-title":"International Clinical Psychopharmacology"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib24","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0165-1781(03)00220-8","article-title":"Decrease dantioxidant enzymes and membrane essential polyunsaturatiod fatty acids in schizophrenic and bipolar mood disorder patients","volume":"121","author":"Ranjekar","year":"2003","journal-title":"Psychiatry Research"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib25","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0165-0327(00)00321-9","article-title":"S-100B is increased in melancholic but not in non-melancholic major depression","volume":"66","author":"Rothermundt","year":"2001","journal-title":"Journal of Affective Disorders"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib26","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1002\/jemt.10303","article-title":"S100B in brain damage and neurodegeneration","volume":"60","author":"Rothermundt","year":"2003","journal-title":"Microscopy Research and Technique"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib27","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1080\/15622970510029993","article-title":"Elevated serum nitric oxide and superoxide dismutase in euthymic bipolar patients: impact of past episodes","volume":"1","author":"Savas","year":"2006","journal-title":"World Journal of Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib28","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1097\/00001756-200209160-00021","article-title":"S100B is increased in mood disorders and may be reduced by antidepressive treatment","volume":"13","author":"Schroeter","year":"2002","journal-title":"Neuroreport"},{"issue":"11","key":"10.1016\/j.jpsychires.2006.07.013_bib29","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.biopsych.2005.04.052","article-title":"Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells","volume":"58","author":"Shao","year":"2005","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib30","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.pneurobio.2004.02.001","article-title":"Astrocyte apoptosis: implications for neuroprotection","volume":"72","author":"Takuma","year":"2004","journal-title":"Progress in Neurobiology"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib31","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/S1385-299X(00)00041-6","article-title":"Digitonin-permeabilization of astrocytes in culture monitored by trypan blue exclusion and loss of S100B by ELISA","volume":"6","author":"Tramontina","year":"2000","journal-title":"Brain Research Protocols"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib32","doi-asserted-by":"crossref","first-page":"97","DOI":"10.3233\/RNN-2003-00230","article-title":"The Janus face of glial-derived S100B: beneficial and detrimental functions in the brain","volume":"21","author":"Van Eldik","year":"2003","journal-title":"Restorative Neurology and Neuroscience"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib33","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0076-6879(81)77046-0","article-title":"Glutathione peroxidase","volume":"77","author":"Wendel","year":"1981","journal-title":"Methods in Enzymology"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib34","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1016\/S0006-3223(98)00217-0","article-title":"Elevated plasma levels of S-100b protein in schizophrenic patients","volume":"45","author":"Wiesmann","year":"1999","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib35","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1042\/bj0990667","article-title":"Mechanism of lipid peroxide formation in animal tissues","volume":"99","author":"Wills","year":"1966","journal-title":"Biochemical Journal"},{"key":"10.1016\/j.jpsychires.2006.07.013_bib36","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1192\/bjp.133.5.429","article-title":"A rating scale for mania: reliability, validity, and sensitivity","volume":"133","author":"Young","year":"1978","journal-title":"British Journal of Psychiatry"}],"container-title":["Journal of Psychiatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395606001518?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395606001518?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T20:02:53Z","timestamp":1736539373000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022395606001518"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["S0022395606001518"],"URL":"https:\/\/doi.org\/10.1016\/j.jpsychires.2006.07.013","relation":{},"ISSN":["0022-3956"],"issn-type":[{"value":"0022-3956","type":"print"}],"subject":[],"published":{"date-parts":[[2007,9]]}}}