{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T17:28:13Z","timestamp":1769880493255,"version":"3.49.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Psychiatric Research"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.jpsychires.2012.09.013","type":"journal-article","created":{"date-parts":[[2012,10,15]],"date-time":"2012-10-15T19:17:21Z","timestamp":1350328641000},"page":"122-127","source":"Crossref","is-referenced-by-count":31,"title":["Changes in gray matter volume of remitted first-episode, drug-na\u00efve, panic disorder patients after 6-week antidepressant therapy"],"prefix":"10.1016","volume":"47","author":[{"given":"Chien-Han","family":"Lai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Te","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpsychires.2012.09.013_bib1","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1007\/s00213-006-0444-x","article-title":"Effect of acute tryptophan depletion on pre-frontal engagement","volume":"187","author":"Allen","year":"2006","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib2","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.pscychresns.2008.10.004","article-title":"Sexually dimorphic gray matter volume reduction in patients with panic disorder","volume":"173","author":"Asami","year":"2009","journal-title":"Psychiatry Research"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib3","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.cortex.2010.07.001","article-title":"Role of the precentral gyrus of the insula in complex articulation","volume":"47","author":"Baldo","year":"2011","journal-title":"Cortex"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib4","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S0006-3223(02)01355-0","article-title":"rCBF differences between panic disorder patients and control subjects during anticipatory anxiety and rest","volume":"52","author":"Boshuisen","year":"2002","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib5","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1017\/S1461145708009309","article-title":"A\u00a0systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression","volume":"11","author":"Brunoni","year":"2008","journal-title":"International Journal of Neuropsychopharmacology"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib6","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1001\/archpsyc.64.7.793","article-title":"Reduced gamma-aminobutyric acid(A)-benzodiazepine binding sites in insular cortex of individuals with panic disorder","volume":"64","author":"Cameron","year":"2007","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib7","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1097\/00006842-200007000-00014","article-title":"Effects of yohimbine on cerebral blood flow, symptoms, and physiological functions in humans","volume":"62","author":"Cameron","year":"2000","journal-title":"Psychosomatic Medicine"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib8","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1152\/jn.00955.2003","article-title":"Sensorimotor integration in the precentral gyrus: polysensory neurons and defensive movements","volume":"91","author":"Cooke","year":"2004","journal-title":"Journal of Neurophysiology"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib9","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1097\/YCO.0b013e328319bd10","article-title":"Current status of brain imaging in anxiety disorders","volume":"22","author":"Damsa","year":"2009","journal-title":"Current Opinion in Psychiatry"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib10","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.neuroimage.2010.11.040","article-title":"Experiential, autonomic, and neural responses during threat anticipation vary as a function of threat intensity and neuroticism","volume":"55","author":"Drabant","year":"2011","journal-title":"Neuroimage"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib11","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0924-977X(02)00102-5","article-title":"Functional anatomical correlates of antidepressant drug treatment assessed using PET measures of regional glucose metabolism","volume":"12","author":"Drevets","year":"2002","journal-title":"European Neuropsychopharmacology"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib12","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1002\/hbm.20522","article-title":"Functional neuroanatomy of CCK-4-induced panic attacks in healthy volunteers","volume":"30","author":"Eser","year":"2009","journal-title":"Human Brain Mapping"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib13","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1176\/appi.ajp.157.4.493","article-title":"Neuroanatomical hypothesis of panic disorder, revised","volume":"157","author":"Gorman","year":"2000","journal-title":"American Journal of Psychiatry"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib14","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1016\/j.neubiorev.2008.05.017","article-title":"Neurobiology of panic disorder: from animal models to brain neuroimaging","volume":"32","author":"Graeff","year":"2008","journal-title":"Neuroscience & Biobehavioral Reviews"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib15","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s002210000518","article-title":"Location of the polysensory zone in the precentral gyrus of anesthetized monkeys","volume":"135","author":"Graziano","year":"2000","journal-title":"Experimental Brain Research"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2003.11.064","article-title":"Mechanisms of action of the antidepressants fluoxetine and the substance P antagonist L-000760735 are associated with altered neurofilaments and synaptic remodeling","volume":"1002","author":"Guest","year":"2004","journal-title":"Brain Research"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib17","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1016\/j.neuroimage.2011.03.059","article-title":"Modulating inhibitory control with direct current stimulation of the superior medial frontal cortex","volume":"56","author":"Hsu","year":"2011","journal-title":"Neuroimage"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib18","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/S0006-3223(99)00103-1","article-title":"Regional brain activity during transient self-induced anxiety and anger in healthy adults","volume":"46","author":"Kimbrell","year":"1999","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib19","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.biopsych.2004.07.008","article-title":"Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat","volume":"56","author":"Kodama","year":"2004","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib20","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1097\/00006231-199504000-00159","article-title":"Abnormal\u00a0regional benzodiazepine receptor uptake in the prefrontal cortex in\u00a0patients with panic disorder","volume":"16","author":"Kuikka","year":"1995","journal-title":"Nuclear Medicine Communications"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib21","doi-asserted-by":"crossref","first-page":"39","DOI":"10.55782\/ane-2003-1453","article-title":"Central control of heart rate changes during visual affective processing as revealed by fMRI","volume":"63","author":"Kuniecki","year":"2003","journal-title":"Acta Neurobiologiae Experimentalis (Warsaw)"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib22","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1017\/S1461145710000829","article-title":"A\u00a0subtle grey-matter increase in first-episode, drug-naive major depressive disorder with panic disorder after 6 weeks' duloxetine therapy","volume":"14","author":"Lai","year":"2011","journal-title":"International Journal of Neuropsychopharmacology"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib23","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.euroneuro.2010.06.002","article-title":"First episode drug-naive major depressive disorder with panic disorder: gray matter deficits in limbic and default network structures","volume":"20","author":"Lai","year":"2010","journal-title":"European Neuropsychopharmacology"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib24","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1177\/0269881109349835","article-title":"Escitalopram \u2013 translating molecular properties into clinical benefit: reviewing the evidence in major depression","volume":"24","author":"Leonard","year":"2010","journal-title":"Journal of Psychopharmacology"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib25","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.neuroimage.2009.11.021","article-title":"Structural and cognitive deficits in remitting and non-remitting recurrent depression: a voxel-based morphometric study","volume":"50","author":"Li","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib26","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1016\/j.neuroimage.2010.05.010","article-title":"Selective aberrant functional connectivity of resting state networks in social anxiety disorder","volume":"52","author":"Liao","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib27","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/S0006-8993(00)02945-0","article-title":"Cellular bases of functional brain imaging: insights from neuron-glia metabolic coupling","volume":"886","author":"Magistretti","year":"2000","journal-title":"Brain Research"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib28","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1001\/archpsyc.55.8.715","article-title":"Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: preliminary results from a quantitative PET study","volume":"55","author":"Malizia","year":"1998","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib29","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0165-0327(02)00044-7","article-title":"Glia as a putative target for antidepressant treatments","volume":"75","author":"Manev","year":"2003","journal-title":"Journal of Affective Disorders"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib30","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1001\/archpsyc.58.7.641","article-title":"Brain blood flow changes in depressed patients treated with interpersonal psychotherapy or venlafaxine hydrochloride: preliminary findings","volume":"58","author":"Martin","year":"2001","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib31","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.eurpsy.2007.02.006","article-title":"Insular cortex and neuropsychiatric disorders: a review of recent literature","volume":"22","author":"Nagai","year":"2007","journal-title":"European Psychiatry"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/hbm.1058","article-title":"Nonparametric permutation tests for functional neuroimaging: a primer with examples","volume":"15","author":"Nichols","year":"2002","journal-title":"Human Brain Mapping"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib33","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0028-3932(71)90067-4","article-title":"The assessment and analysis of handedness: the Edinburgh inventory","volume":"9","author":"Oldfield","year":"1971","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib34","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/j.1440-1819.2010.02085.x","article-title":"Posterior orbitofrontal sulcogyral pattern associated with orbitofrontal cortex volume reduction and anxiety trait in panic disorder","volume":"64","author":"Roppongi","year":"2010","journal-title":"Psychiatry and Clinical Neurosciences"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib35","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.biopsych.2010.09.053","article-title":"Gray matter alterations in adults with attention-deficit\/hyperactivity disorder identified by voxel based morphometry","volume":"69","author":"Seidman","year":"2011","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib36","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.pscychresns.2007.12.014","article-title":"Impact of fluoxetine on the human brain in multiple sclerosis as quantified by proton magnetic resonance spectroscopy and diffusion tensor imaging","volume":"164","author":"Sijens","year":"2008","journal-title":"Psychiatry Research"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib37","doi-asserted-by":"crossref","first-page":"215","DOI":"10.4306\/pi.2010.7.3.215","article-title":"Changes in cerebral cortex and limbic brain functions after short-term paroxetine treatment in panic disorder: an [F]FDG-PET pilot study","volume":"7","author":"Sim","year":"2010","journal-title":"Psychiatry Investigation"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib38","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1002\/syn.10088","article-title":"Serotonin modulation of cerebral glucose metabolism measured with positron emission tomography (PET) in human subjects","volume":"45","author":"Smith","year":"2002","journal-title":"Synapse"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib39","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1017\/S0033291709991930","article-title":"Temporal and right frontal lobe alterations in panic disorder: a quantitative volumetric and voxel-based morphometric MRI study","volume":"40","author":"Sobanski","year":"2010","journal-title":"Psychological Medicine"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2009.05.097","article-title":"Functional but not structural changes associated with learning: an exploration of longitudinal voxel-based morphometry (VBM)","author":"Thomas","year":"2009","journal-title":"Neuroimage"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib41","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.pscychresns.2007.04.015","article-title":"Regional gray matter abnormalities in panic disorder: a voxel-based morphometry study","volume":"163","author":"Uchida","year":"2008","journal-title":"Psychiatry Research"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib42","doi-asserted-by":"crossref","first-page":"87","DOI":"10.2174\/187152707780363302","article-title":"Metabotropic glutamate receptors in the control of mood disorders","volume":"6","author":"Witkin","year":"2007","journal-title":"CNS & Neurological Disorders \u2013 Drug Targets"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib43","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1111\/j.1460-9568.2005.04394.x","article-title":"Putaminal gray matter volume decrease in panic disorder: an optimized voxel-based morphometry study","volume":"22","author":"Yoo","year":"2005","journal-title":"European Journal of Neuroscience"},{"key":"10.1016\/j.jpsychires.2012.09.013_bib44","article-title":"Resting-state functional connectivity of the medial superior frontal cortex","author":"Zhang","year":"2011","journal-title":"Cerebral Cortex"}],"container-title":["Journal of Psychiatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002239561200283X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002239561200283X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T08:18:04Z","timestamp":1714465084000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002239561200283X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S002239561200283X"],"URL":"https:\/\/doi.org\/10.1016\/j.jpsychires.2012.09.013","relation":{},"ISSN":["0022-3956"],"issn-type":[{"value":"0022-3956","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}