{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T03:45:33Z","timestamp":1793850333195,"version":"4.6.1"},"reference-count":35,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Psychiatric Research"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1016\/j.jpsychires.2013.01.023","type":"journal-article","created":{"date-parts":[[2013,3,27]],"date-time":"2013-03-27T08:47:41Z","timestamp":1364374061000},"page":"995-998","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"title":["Effect of traumatic imagery on cerebrospinal fluid dopamine and serotonin metabolites in posttraumatic stress disorder"],"prefix":"10.1016","volume":"47","author":[{"suffix":"Jr.","given":"Thomas D.","family":"Geracioti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"Jefferson-Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey R.","family":"Strawn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dewleen G.","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris A.","family":"Dashevsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul S.","family":"Horn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nosakhare N.","family":"Ekhator","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpsychires.2013.01.023_bib1","first-page":"215","article-title":"Measurement of mood","volume":"4","author":"Aitken","year":"1970","journal-title":"British Journal of Hospital Medicine"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib2","doi-asserted-by":"crossref","first-page":"2376","DOI":"10.1038\/sj.npp.1301164","article-title":"Stimulants: therapeutic actions in ADHD","volume":"31","author":"Arnsten","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib3","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.psychres.2010.04.043","article-title":"PTSD and dopaminergic genes DRD2 and DAT in multigenerational families exposed to the Spitak earthquake","volume":"178","author":"Bailey","year":"2010","journal-title":"Psychiatry Research"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib5","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1097\/JCP.0b013e318032eaed","article-title":"A\u00a0placebo-controlled trial of bupropion SR in the treatment of chronic posttraumatic stress disorder","volume":"27","author":"Becker","year":"2007","journal-title":"Journal of Clinical Psychopharmacology"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib6","first-page":"75","article-title":"The development of a clinician-administered PTSD Scale","volume":"8","author":"Blake","year":"1995","journal-title":"Journal of Traumatic Stress"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib7","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1001\/jama.283.14.1837","article-title":"Efficacy and safety of sertraline treatment of posttraumatic stress disorder: a randomized controlled trial","volume":"283","author":"Brady","year":"2000","journal-title":"Journal of the American Medical Association"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib8","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.neubiorev.2006.10.001","article-title":"The genetic background to PTSD","volume":"31","author":"Broekman","year":"2007","journal-title":"Neuroscience & Biobehavioral Reviews"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib9","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.neubiorev.2011.04.012","article-title":"The mesoaccumbens dopamine in coping with stress","volume":"36","author":"Cabib","year":"2012","journal-title":"Neuroscience & Biobehavioral Reviews"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib10","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/1099-1077(200006)15:4<295::AID-HUP166>3.0.CO;2-O","article-title":"The use of stimulants in the treatment of post traumatic stress disorder: case report","volume":"15","author":"Daly","year":"2000","journal-title":"Human Psychopharmacology"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib11","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1001\/archpsyc.58.5.485","article-title":"Multicenter, double-blind comparison of sertraline and placebo in the treatment of posttraumatic stress disorder","volume":"58","author":"Davidson","year":"2001","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib12","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.psyneuen.2007.12.012","article-title":"Effect of trauma-related audiovisual stimulation on cerebrospinal fluid norepinephrine and corticotropin-releasing hormone concentrations in post-traumatic stress disorder","volume":"33","author":"Geracioti","year":"2008","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib13","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S0006-3223(97)90372-3","article-title":"Continuous covariability of dopamine and serotonin metabolites in human cerebrospinal fluid","volume":"44","author":"Geracioti","year":"1998","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib14","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1176\/ajp.156.1.130","article-title":"Low CSF concentration of a dopamine metabolite in tobacco smokers","volume":"156","author":"Geracioti","year":"1999","journal-title":"American Journal of Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib15","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1038\/sj.bjp.0705396","article-title":"Differences in the mechanisms that increase noradrenaline eflux after administration of d-amphetamine: a dual-probe microdialysis study in rat frontal cortex and hypothalamus","volume":"139","author":"Geranton","year":"2003","journal-title":"British Journal of Pharmacology"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib16","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A\u00a0rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"Journal of Neurology, Neurosurgery & Psychiatry"},{"issue":"1","key":"10.1016\/j.jpsychires.2013.01.023_bib17","first-page":"1","article-title":"Adjunctive risperidone treatment in post-traumatic stress disorder: a preliminary controlled trial of effects on comorbid psychotic symptoms","volume":"18","author":"Hamner","year":"2003","journal-title":"International Clinical Psychopharmacology"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib18","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1586\/14737175.5.2.267","article-title":"Emerging roles for atypical antipsychotics in chronic post-traumatic stress disorder","volume":"5","author":"Hamner","year":"2005","journal-title":"Expert Review of Neurotherapeutics"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib19","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1471-2210-6-6","article-title":"Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs","volume":"3","author":"Han","year":"2006","journal-title":"BMC Pharmacology"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib20","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3109\/10401230009147096","article-title":"Lack of efficacy for fluoxetine in PTSD: a placebo controlled trial in combat veterans","volume":"12","author":"Hertzberg","year":"2000","journal-title":"Annals of Clinical Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib21","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0304-3940(99)00778-8","article-title":"The effect of lumbar puncture stress on dopamine and serotonin metabolites in human cerebrospinal fluid","volume":"276","author":"Hill","year":"1999","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib22","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1177\/0269881110385600","article-title":"Psychostimulant treatment of combat-related posttraumatic stress disorder","volume":"25","author":"Houlihan","year":"2011","journal-title":"Journal of Psychopharmacology"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib23","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/BF00711243","article-title":"A\u00a0new approach to biochemical evaluation of brain dopamine metabolism","volume":"8","author":"Kopin","year":"1988","journal-title":"Cellular and Molecular Neurobiology"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib24","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1001\/jama.2011.1080","article-title":"Adjunctive risperidone treatment for antidepressant-resistant symptoms of chronic military service-related PTSD. A randomized trial","volume":"306","author":"Krystal","year":"2011","journal-title":"Journal of the American Medical Association"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib25","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1016\/j.biopsych.2004.12.036","article-title":"Stimulant actions in rodents: implications for attention-deficit\/hyperactivity disorder treatment and potential substance abuse","volume":"57","author":"Kuczenski","year":"2005","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib26","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1176\/appi.ajp.158.12.1982","article-title":"Efficacy and safety of paroxetine for chronic PTSD: a fixed-dose, placebo-controlled study","volume":"158","author":"Marshall","year":"2001","journal-title":"American Journal of Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib27","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0014-2999(75)90239-3","article-title":"d-Amphetamine as a releaser or reuptake inhibitor of biogenic amines in synaptosomes","volume":"34","author":"Raiteri","year":"1975","journal-title":"European Journal of Pharmacology"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib28","doi-asserted-by":"crossref","first-page":"520","DOI":"10.4088\/JCP.v69n0402","article-title":"Placebo-controlled trial of risperidone augmentation for selective serotonin reuptake inhibitor-resistant civilian posttraumatic stress disorder","volume":"69","author":"Rothbaum","year":"2008","journal-title":"Journal of Clinical Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib29","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.bbr.2010.03.023","article-title":"Neurochemical and behavioral effects elicited by bupropion and diethylpropion","volume":"211","author":"Santamaria","year":"2010","journal-title":"Behavioural Brain Research"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib30","first-page":"159","article-title":"A\u00a0review of the neuropharmacology of buproprion, a dual norepinephrine and dopamine reuptake inhibitor","volume":"6","author":"Stahl","year":"2004","journal-title":"Primary Care Companion to The Journal of Clinical Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib31","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1176\/appi.ajp.159.10.1777","article-title":"Adjunctive olanzapine for SSRI-resistant combat-related PTSD: a double-blind, placebo-controlled study","volume":"159","author":"Stein","year":"2002","journal-title":"American Journal of Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib32","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/S0024-3205(02)01828-3","article-title":"Intra- and inter-individual relationships between central and peripheral serotonergic activity in humans: serial cerebrospinal fluid studies","volume":"71","author":"Strawn","year":"2002","journal-title":"Life Sciences"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib33","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0378-4347(01)00290-0","article-title":"In-use stability of monoamine metabolites in cerebrospinal fluid","volume":"760","author":"Strawn","year":"2001","journal-title":"Journal of Chromatography B"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib34","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s12031-011-9513-7","article-title":"Candidate-gene approach in posttraumatic stress disorder after urban violence: association analysis of the genes encoding serotonin transporter, dopamine transporter, and BDNF","volume":"44","author":"Valente","year":"2011","journal-title":"Journal of Molecular Neuroscience"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib35","first-page":"517","article-title":"Fluoxetine in posttraumatic stress disorder","volume":"55","author":"van der Kolk","year":"1994","journal-title":"Journal of Clinical Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.01.023_bib36","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1097\/00004714-200204000-00013","article-title":"Double-blind, placebo-controlled pilot study of sertraline in military veterans with posttraumatic stress disorder","volume":"22","author":"Zohar","year":"2002","journal-title":"Journal of Clinical Psychopharmacology"}],"container-title":["Journal of Psychiatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395613000460?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395613000460?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T11:08:47Z","timestamp":1758366527000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022395613000460"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":35,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["S0022395613000460"],"URL":"https:\/\/doi.org\/10.1016\/j.jpsychires.2013.01.023","relation":{},"ISSN":["0022-3956"],"issn-type":[{"value":"0022-3956","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of traumatic imagery on cerebrospinal fluid dopamine and serotonin metabolites in posttraumatic stress disorder","name":"articletitle","label":"Article Title"},{"value":"Journal of Psychiatric Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpsychires.2013.01.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}