{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:42:44Z","timestamp":1790505764288,"version":"4.1.0"},"reference-count":54,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Stanford department of Psychiatry"},{"name":"Trichotillomania Learning Center"},{"name":"NIH","award":["RO1NS073498"],"award-info":[{"award-number":["RO1NS073498"]}]},{"name":"NIMH T-32 training","award":["T32 5 MH19938-15"],"award-info":[{"award-number":["T32 5 MH19938-15"]}]}],"content-domain":{"domain":["journalofpsychiatricresearch.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Psychiatric Research"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.jpsychires.2013.05.014","type":"journal-article","created":{"date-parts":[[2013,6,15]],"date-time":"2013-06-15T07:00:24Z","timestamp":1371279624000},"page":"1264-1272","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"title":["Disordered reward processing and functional connectivity in trichotillomania: A pilot study"],"prefix":"10.1016","volume":"47","author":[{"given":"Matthew P.","family":"White","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William R.","family":"Shirer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria J.","family":"Molfino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caitlin","family":"Tenison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica S.","family":"Damoiseaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Greicius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpsychires.2013.05.014_bib1","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.neuron.2008.07.004","article-title":"Basolateral amygdala neurons facilitate reward-seeking behavior by exciting nucleus accumbens neurons","volume":"59","author":"Ambroggi","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib2","series-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"2000"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib3","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/npp.2009.131","article-title":"Human and rodent homologies in action control: corticostriatal determinants of goal-directed and habitual action","volume":"35","author":"Balleine","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib4","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/j.biopsych.2009.04.035","article-title":"Ventral striatal activation during reward anticipation correlates with impulsivity in alcoholics","volume":"66","author":"Beck","year":"2009","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib5","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1037\/0022-006X.56.6.893","article-title":"An inventory for measuring clinical anxiety: psychometric properties","volume":"56","author":"Beck","year":"1988","journal-title":"Journal of Consulting and Clinical Psychology"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib6","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1001\/archpsyc.1961.01710120031004","article-title":"An inventory for measuring depression","volume":"4","author":"Beck","year":"1961","journal-title":"Archives of General Psychiatry"},{"issue":"4","key":"10.1016\/j.jpsychires.2013.05.014_bib7","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1016\/j.neuroimage.2008.06.035","article-title":"Striatal sensitivity to reward deliveries and omissions in substance dependent patients","volume":"42","author":"Bjork","year":"2008","journal-title":"Neuroimage"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib8","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.biopsych.2007.05.019","article-title":"Systematic review: pharmacological and behavioral treatment for trichotillomania","volume":"62","author":"Bloch","year":"2007","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib9","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.mehy.2011.01.005","article-title":"Neuro-chemical activation of brain reward meso-limbic circuitry is associated with relapse prevention and drug hunger: a hypothesis","volume":"76","author":"Blum","year":"2011","journal-title":"Medical Hypotheses"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib10","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.biopsych.2009.10.029","article-title":"Nicotine dependence is characterized by disordered reward processing in a network driving motivation","volume":"67","author":"Buhler","year":"2010","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib11","doi-asserted-by":"crossref","first-page":"2864","DOI":"10.1162\/jocn.2011.21624","article-title":"Functional connectivity and coactivation of the nucleus accumbens: a combined functional connectivity and structure-based meta-analysis","volume":"23","author":"Cauda","year":"2011","journal-title":"Journal of Cognnitive Neuroscience"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib12","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.neubiorev.2004.11.006","article-title":"The neuropsychology of obsessive compulsive disorder: the importance of failures in cognitive and behavioural inhibition as candidate endophenotypic markers","volume":"29","author":"Chamberlain","year":"2005","journal-title":"Neuroscience & Biobehavioral Reviews"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib13","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1001\/archgenpsychiatry.2010.109","article-title":"Reduced brain white matter integrity in trichotillomania: a diffusion tensor imaging study","volume":"67","author":"Chamberlain","year":"2010","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib14","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1192\/bjp.bp.107.048314","article-title":"Grey matter abnormalities in trichotillomania: morphometric magnetic resonance imaging study","volume":"193","author":"Chamberlain","year":"2008","journal-title":"British Journal of Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib15","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.neubiorev.2009.02.002","article-title":"Trichotillomania: neurobiology and treatment","volume":"33","author":"Chamberlain","year":"2009","journal-title":"Neuroscience & Biobehavioral Reviews"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib16","first-page":"415","article-title":"Estimated lifetime prevalence of trichotillomania in college students","volume":"52","author":"Christenson","year":"1991","journal-title":"Journal of Clinical Psychiatry"},{"issue":"4","key":"10.1016\/j.jpsychires.2013.05.014_bib17","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1016\/j.neurobiolaging.2011.06.024","article-title":"Functional connectivity tracks clinical deterioration in Alzheimer's disease","volume":"33","author":"Damoiseaux","year":"2012","journal-title":"Neurobiology of Aging"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib18","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1001\/archneur.64.1.20","article-title":"Circuits and circuit disorders of the basal ganglia","volume":"64","author":"DeLong","year":"2007","journal-title":"Archives of Neurology"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib19","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.tics.2010.11.004","article-title":"Emotional processing in anterior cingulate and medial prefrontal cortex","volume":"15","author":"Etkin","year":"2011","journal-title":"Trends in Cognitive Science"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib20","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.psychres.2008.06.008","article-title":"Tourette's syndrome, trichotillomania, and obsessive-compulsive disorder: how closely are they related?","volume":"170","author":"Ferrao","year":"2009","journal-title":"Psychiatry Research"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib21","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/j.biopsych.2010.12.003","article-title":"Dysfunctional reward circuitry in obsessive-compulsive disorder","volume":"69","author":"Figee","year":"2010","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib22","doi-asserted-by":"crossref","first-page":"7209","DOI":"10.1073\/pnas.0811879106","article-title":"Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele","volume":"106","author":"Filippini","year":"2009","journal-title":"Proceedings of the National Academy of Science U S A"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib23","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s10578-008-0118-5","article-title":"Cross-sectional study of women with trichotillomania: a preliminary examination of pulling styles, severity, phenomenology, and functional impact","volume":"40","author":"Flessner","year":"2009","journal-title":"Child Psychiatry and Human Development"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib24","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1002\/mrm.1222","article-title":"Spiral-in\/out BOLD fMRI for increased SNR and reduced susceptibility artifacts","volume":"46","author":"Glover","year":"2001","journal-title":"Magnetic Resonance in Medicine"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib25","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1002\/1522-2594(200007)44:1<162::AID-MRM23>3.0.CO;2-E","article-title":"Image-based method for retrospective correction of physiological motion effects in fMRI: RETROICOR","volume":"44","author":"Glover","year":"2000","journal-title":"Magnetic Resonance in Medicine"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib26","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1001\/archgenpsychiatry.2009.60","article-title":"N-acetylcysteine, a glutamate modulator, in the treatment of trichotillomania: a double-blind, placebo-controlled study","volume":"66","author":"Grant","year":"2009","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib27","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1001\/archgenpsychiatry.2009.2","article-title":"Association of nicotine addiction and nicotine's actions with separate cingulate cortex functional circuits","volume":"66","author":"Hong","year":"2009","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib28","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1176\/appi.ajp.2011.10101446","article-title":"Nitric oxide synthase genotype modulation of impulsivity and ventral striatal activity in adult ADHD patients and healthy comparison subjects","volume":"168","author":"Hoogman","year":"2011","journal-title":"American Journal of Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib29","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.biopsych.2011.05.008","article-title":"An\u00a0initial study of neural responses to monetary incentives as related to treatment outcome in cocaine dependence","volume":"70","author":"Jia","year":"2011","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib30","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1176\/appi.ajp.162.8.1403","article-title":"The neural basis of addiction: a pathology of motivation and choice","volume":"162","author":"Kalivas","year":"2005","journal-title":"American Journal of Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib31","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.biopsych.2006.06.013","article-title":"Evidence for reduced cerebellar volumes in trichotillomania","volume":"61","author":"Keuthen","year":"2007","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib32","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1159\/000289003","article-title":"The Massachusetts General Hospital (MGH) Hairpulling Scale: 1. Development and factor analyses","volume":"64","author":"Keuthen","year":"1995","journal-title":"Psychotherapeutics Psychosomatics"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib33","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.biopsych.2007.07.023","article-title":"Neural responses to monetary incentives in major depression","volume":"63","author":"Knutson","year":"2008","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib34","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S1053-8119(02)00057-5","article-title":"A\u00a0region of mesial prefrontal cortex tracks monetarily rewarding outcomes: characterization with rapid event-related fMRI","volume":"18","author":"Knutson","year":"2003","journal-title":"Neuroimage"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib35","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/npp.2009.110","article-title":"Neurocircuitry of addiction","volume":"35","author":"Koob","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib36","doi-asserted-by":"crossref","first-page":"14734","DOI":"10.1523\/JNEUROSCI.3765-09.2009","article-title":"Striatal dopamine d2\/d3 receptor availability is reduced in methamphetamine dependence and is linked to impulsivity","volume":"29","author":"Lee","year":"2009","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib37","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1016\/j.pnpbp.2010.06.031","article-title":"A\u00a0pilot study of brain activation in children with trichotillomania during a visual-tactile symptom provocation task: a functional magnetic resonance imaging study","volume":"34","author":"Lee","year":"2010","journal-title":"Progress in Neuropsychopharmacology & Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib38","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/j.neubiorev.2010.12.012","article-title":"Common and distinct networks underlying reward valence and processing stages: a meta-analysis of functional neuroimaging studies","volume":"35","author":"Liu","year":"2010","journal-title":"Neuroscience & Biobehavioral Reviews"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib39","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0006-3223(96)00297-1","article-title":"Reduced basal ganglia volumes in trichotillomania measured via morphometric magnetic resonance imaging","volume":"42","author":"O'Sullivan","year":"1997","journal-title":"Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib40","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1176\/appi.ajp.2008.08081201","article-title":"Reduced caudate and nucleus accumbens response to rewards in unmedicated individuals with major depressive disorder","volume":"166","author":"Pizzagalli","year":"2009","journal-title":"American Journal of Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib41","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.pscychresns.2006.09.002","article-title":"Brain activation during implicit sequence learning in individuals with trichotillomania","volume":"154","author":"Rauch","year":"2007","journal-title":"Psychiatry Research"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib42","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/j.neuron.2011.05.014","article-title":"Frontal cortex and reward-guided learning and decision-making","volume":"70","author":"Rushworth","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib43","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1038\/nrn2994","article-title":"The integration of negative affect, pain and cognitive control in the cingulate cortex","volume":"12","author":"Shackman","year":"2011","journal-title":"National Review of Neuroscience"},{"issue":"Suppl. 20","key":"10.1016\/j.jpsychires.2013.05.014_bib44","first-page":"22","article-title":"The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10","volume":"59","author":"Sheehan","year":"1998","journal-title":"Journal of Clinical Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib45","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.neuroimage.2008.03.061","article-title":"Threshold-free cluster enhancement: addressing problems of smoothing, threshold dependence and localisation in cluster inference","volume":"44","author":"Smith","year":"2009","journal-title":"Neuroimage"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib46","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.jad.2009.01.034","article-title":"fMRI of alterations in reward selection, anticipation, and feedback in major depressive disorder","volume":"118","author":"Smoski","year":"2009","journal-title":"Journal of Affective Disorders"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib47","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0925-4927(97)00010-3","article-title":"Magnetic resonance brain imaging in women with obsessive-compulsive disorder and trichotillomania","volume":"74","author":"Stein","year":"1997","journal-title":"Psychiatry Research"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib48","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.psc.2006.02.015","article-title":"Obsessive-compulsive spectrum disorders: a multidimensional approach","volume":"29","author":"Stein","year":"2006","journal-title":"Psychiatric Clinics of North America"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib49","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/S0278-5846(01)00334-7","article-title":"Functional brain imaging and pharmacotherapy in trichotillomania. Single photon emission computed tomography before and after treatment with the selective serotonin reuptake inhibitor citalopram","volume":"26","author":"Stein","year":"2002","journal-title":"Progress in Neuropsychopharmacology & Biological Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib50","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1001\/archpsyc.1991.01810330052008","article-title":"Regional cerebral glucose metabolism of women with trichotillomania","volume":"48","author":"Swedo","year":"1991","journal-title":"Archives of General Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib51","doi-asserted-by":"crossref","first-page":"2098","DOI":"10.1093\/brain\/awq138","article-title":"Alterations in brain structure and functional connectivity in prescription opioid-dependent patients","volume":"133","author":"Upadhyay","year":"2010","journal-title":"Brain"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib52","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.4088\/JCP.09m05114gre","article-title":"A\u00a0randomized, double-blind, placebo-controlled trial of olanzapine in the treatment of trichotillomania","volume":"71","author":"Van Ameringen","year":"2010","journal-title":"Journal of Clinical Psychiatry"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib53","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1097\/JCP.0b013e318221b1ba","article-title":"Open-label trial of aripiprazole in the treatment of trichotillomania","volume":"31","author":"White","year":"2011","journal-title":"Journal of Clinical Psychopharmacology"},{"key":"10.1016\/j.jpsychires.2013.05.014_bib54","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/j.neuroimage.2006.11.043","article-title":"Dysfunction of reward processing correlates with alcohol craving in detoxified alcoholics","volume":"35","author":"Wrase","year":"2007","journal-title":"Neuroimage"}],"container-title":["Journal of Psychiatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395613001544?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395613001544?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,15]],"date-time":"2018-10-15T03:26:38Z","timestamp":1539573998000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022395613001544"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":54,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["S0022395613001544"],"URL":"https:\/\/doi.org\/10.1016\/j.jpsychires.2013.05.014","relation":{},"ISSN":["0022-3956"],"issn-type":[{"value":"0022-3956","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Disordered reward processing and functional connectivity in trichotillomania: A pilot study","name":"articletitle","label":"Article Title"},{"value":"Journal of Psychiatric Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpsychires.2013.05.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}