{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T22:58:49Z","timestamp":1790377129481,"version":"4.1.0"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000025","name":"NIMH","doi-asserted-by":"publisher","award":["MH078113"],"award-info":[{"award-number":["MH078113"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"NIMH","doi-asserted-by":"publisher","award":["MH077945"],"award-info":[{"award-number":["MH077945"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"NIMH","doi-asserted-by":"publisher","award":["MH077852"],"award-info":[{"award-number":["MH077852"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"NIMH","doi-asserted-by":"publisher","award":["MH077851"],"award-info":[{"award-number":["MH077851"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"NIMH","doi-asserted-by":"publisher","award":["MH077862"],"award-info":[{"award-number":["MH077862"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"NIMH","doi-asserted-by":"publisher","award":["MH072767"],"award-info":[{"award-number":["MH072767"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"NIMH","doi-asserted-by":"publisher","award":["MH083888"],"award-info":[{"award-number":["MH083888"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journalofpsychiatricresearch.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Psychiatric Research"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1016\/j.jpsychires.2014.12.008","type":"journal-article","created":{"date-parts":[[2014,12,23]],"date-time":"2014-12-23T09:49:18Z","timestamp":1419328158000},"page":"180-187","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"special_numbering":"C","title":["Effects of lithium on cortical thickness and hippocampal subfield volumes in psychotic bipolar disorder"],"prefix":"10.1016","volume":"61","author":[{"given":"C.I.","family":"Giakoumatos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Nanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.T.","family":"Mathew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Tandon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.R.","family":"Bishop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.A.","family":"Clementz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.D.","family":"Pearlson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.A.","family":"Sweeney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.A.","family":"Tamminga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.S.","family":"Keshavan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jpsychires.2014.12.008_bib1","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0006-3223(00)00836-2","article-title":"An MRI study of temporal lobe structures in men with bipolar disorder or schizophrenia","volume":"48","author":"Altshuler","year":"2000","journal-title":"Biol Psychiatry"},{"issue":"1","key":"10.1016\/j.jpsychires.2014.12.008_bib2","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.biopsych.2006.10.027","article-title":"Greater cortical gray matter density in lithium-treated patients with bipolar disorder","volume":"62","author":"Bearden","year":"2007","journal-title":"Biol Psychiatry"},{"issue":"4","key":"10.1016\/j.jpsychires.2014.12.008_bib3","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.biopsych.2010.07.028","article-title":"Disruption of white matter integrity in bipolar depression as a possible structural marker of illness","volume":"69","author":"Benedetti","year":"2011","journal-title":"Biol Psychiatry"},{"issue":"4","key":"10.1016\/j.jpsychires.2014.12.008_bib4","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1017\/S1461145701002668","article-title":"Perspectives on the use of anticonvulsants in the treatment of bipolar disorder","volume":"4","author":"Brambilla","year":"2001","journal-title":"Int J Neuropsychopharmacol"},{"issue":"4","key":"10.1016\/j.jpsychires.2014.12.008_bib5","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0022-3956(03)00024-4","article-title":"MRI investigation of temporal lobe structures in bipolar patients","volume":"37","author":"Brambilla","year":"2003","journal-title":"J\u00a0Psychiatr Res"},{"issue":"10","key":"10.1016\/j.jpsychires.2014.12.008_bib6","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1038\/sj.npp.1300520","article-title":"1H MRS study of dorsolateral prefrontal cortex in healthy individuals before and after lithium administration","volume":"29","author":"Brambilla","year":"2004","journal-title":"Neuropsychopharmacol"},{"issue":"8","key":"10.1016\/j.jpsychires.2014.12.008_bib7","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1038\/sj.npp.1300189","article-title":"Chronic lithium treatment inhibits pilocarpine-induced mossy fiber sprouting in rat hippocampus","volume":"28","author":"Cadotte","year":"2003","journal-title":"Neuropsychopharmacol"},{"issue":"4","key":"10.1016\/j.jpsychires.2014.12.008_bib8","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1046\/j.1471-4159.2000.0751729.x","article-title":"Enhancement of hippocampal neurogenesis by lithium","volume":"75","author":"Chen","year":"2002","journal-title":"J\u00a0Neurochem"},{"issue":"2","key":"10.1016\/j.jpsychires.2014.12.008_bib9","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1046\/j.1471-4159.1999.720879.x","article-title":"The mood-stabilizing agents lithium and valproate robustlincrease the levels of the neuroprotective protein bcl-2 in the CNS","volume":"72","author":"Chen","year":"2002","journal-title":"J\u00a0Neurochem"},{"issue":"4","key":"10.1016\/j.jpsychires.2014.12.008_bib10","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0893-133X(00)00207-4","article-title":"Decreased anterior cingulate myo-inositol\/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder","volume":"24","author":"Davanzo","year":"2001","journal-title":"Neuropsychopharmacol"},{"issue":"12","key":"10.1016\/j.jpsychires.2014.12.008_bib11","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1097\/JGP.0b013e3181b7f0e2","article-title":"Neuroanatomical and neuropsychological features of euthymic patients with bipolar disorder","volume":"17","author":"Delaloye","year":"2009","journal-title":"Am J Geriatr Psychiatry"},{"issue":"3","key":"10.1016\/j.jpsychires.2014.12.008_bib12","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.neuroimage.2006.01.021","article-title":"An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest","volume":"31","author":"Desikan","year":"2006","journal-title":"NeuroImage"},{"issue":"1","key":"10.1016\/j.jpsychires.2014.12.008_bib13","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1089\/cap.2008.044","article-title":"Randomized double-blind placebo-controlled trial of lithium in youths with severe mood dysregulation","volume":"19","author":"Dickstein","year":"2009","journal-title":"J\u00a0Child Adolesc Psychopharmacol"},{"key":"10.1016\/j.jpsychires.2014.12.008_bib14","doi-asserted-by":"crossref","first-page":"493","DOI":"10.2147\/NDT.S33086","article-title":"Lithium and neuroprotection: translational evidence and implications for the treatment of neuropsychiatric disorders","volume":"9","author":"Diniz","year":"2013","journal-title":"Neuropsychiatric Dis Treat"},{"issue":"14","key":"10.1016\/j.jpsychires.2014.12.008_bib15","doi-asserted-by":"crossref","first-page":"8363","DOI":"10.1073\/pnas.95.14.8363","article-title":"Lithium acutely inhibits and chronically up-regulates and stabilizes glutamate uptake by presynaptic nerve endings in mouse cerebral cortex","volume":"95","author":"Dixon","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"issue":"17","key":"10.1016\/j.jpsychires.2014.12.008_bib16","doi-asserted-by":"crossref","first-page":"3775","DOI":"10.1097\/00001756-200011270-00036","article-title":"Increased hippocampal supragranular timm staining in subjects with bipolar disorder","volume":"11","author":"Dowlatshahi","year":"2000","journal-title":"NeuroReport"},{"key":"10.1016\/j.jpsychires.2014.12.008_bib17","series-title":"User's guide for the structured clinical interview for DSM-IV axis I disorders: SCID-1 clinician version","author":"First","year":"1997"},{"issue":"2","key":"10.1016\/j.jpsychires.2014.12.008_bib18","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.neuroimage.2012.01.021","article-title":"FreeSurfer","volume":"62","author":"Fischl","year":"2012","journal-title":"NeuroImage"},{"issue":"5","key":"10.1016\/j.jpsychires.2014.12.008_bib19","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1176\/appi.ajp.2010.10060896","article-title":"Investigation of cortical thickness abnormalities in lithium-free adults with bipolar I disorder using cortical pattern matching","volume":"168","author":"Foland-Ross","year":"2011","journal-title":"Am J Psychiatry"},{"issue":"3","key":"10.1016\/j.jpsychires.2014.12.008_bib20","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.pscychresns.2012.08.002","article-title":"Three-dimensional mapping of hippocampal and amygdala structure in euthymic adults with bipolar disorder not treated lithium","volume":"211","author":"Foland-Ross","year":"2013","journal-title":"Psychiatry Res Neuroimaging"},{"issue":"5","key":"10.1016\/j.jpsychires.2014.12.008_bib21","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1192\/bjp.bp.110.080044","article-title":"Disease-modifying properties of long-term lithium treatment for amnestic mild cognitive impairment: randomised controlled trial","volume":"198","author":"Forlenza","year":"2011","journal-title":"Br J Psychiatry"},{"issue":"5","key":"10.1016\/j.jpsychires.2014.12.008_bib22","doi-asserted-by":"crossref","first-page":"335","DOI":"10.2165\/11599180-000000000-00000","article-title":"Does lithium prevent Alzheimer's disease?","volume":"29","author":"Forlenza","year":"2012","journal-title":"Drugs Aging"},{"issue":"2","key":"10.1016\/j.jpsychires.2014.12.008_bib23","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.pscychresns.2007.06.004","article-title":"Anatomical abnormalities of the anterior cingulate and paracingulate cortex in patients with bipolar I disorder","volume":"162","author":"Fornito","year":"2008","journal-title":"Psychiatry Res"},{"issue":"5","key":"10.1016\/j.jpsychires.2014.12.008_bib24","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.biopsych.2004.06.012","article-title":"Lithium and valproic acid treatment effects on brain chemistry in bipolar disorder","volume":"56","author":"Friedman","year":"2004","journal-title":"Biol Psychiatry"},{"issue":"1","key":"10.1016\/j.jpsychires.2014.12.008_bib25","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/s002130100871","article-title":"Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain","volume":"158","author":"Fukumoto","year":"2001","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.jpsychires.2014.12.008_bib26","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1001\/jama.290.11.1467","article-title":"Suicide risk in bipolar disorder during treatment with lithium and divalproex","volume":"290","author":"Goodwin","year":"2003","journal-title":"JAMA"},{"issue":"3","key":"10.1016\/j.jpsychires.2014.12.008_bib27","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/j.1399-5618.2012.01013.x","article-title":"Hippocampal volumes in bipolar disorders: opposing effects of illness burden and lithium treatment","volume":"14","author":"Hajek","year":"2012","journal-title":"Bipolar Disord"},{"issue":"5","key":"10.1016\/j.jpsychires.2014.12.008_bib28","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1503\/jpn.110143","article-title":"Smaller hippocampal volumes in patients with bipolar disorder are masked by exposure to lithium: a meta-analysis","volume":"37","author":"Hajek","year":"2012","journal-title":"J\u00a0Psychiatry Neurosci"},{"issue":"3","key":"10.1016\/j.jpsychires.2014.12.008_bib29","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1017\/S0033291713001165","article-title":"Neuroprotective effect of lithium on hippocampal volumes in bipolar disorder independent of long-term treatment response","volume":"44","author":"Hajek","year":"2014","journal-title":"Psychol Med"},{"issue":"4","key":"10.1016\/j.jpsychires.2014.12.008_bib30","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.biopsych.2010.08.029","article-title":"Structural magnetic resonance imaging in bipolar disorder: an international collaborative mega-analysis of individual adult patient data","volume":"69","author":"Hallahan","year":"2011","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.jpsychires.2014.12.008_bib31","series-title":"Four factor index of social status","author":"Hollingshead","year":"1975"},{"issue":"5","key":"10.1016\/j.jpsychires.2014.12.008_bib32","doi-asserted-by":"crossref","first-page":"389","DOI":"10.2165\/00023210-200620050-00004","article-title":"Mechanism of action of atypical antipsychotic drugs and the neurobiology of schizophrenia","volume":"20","author":"Horacek","year":"2006","journal-title":"CNS Drugs"},{"issue":"11","key":"10.1016\/j.jpsychires.2014.12.008_bib33","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1176\/appi.ajp.2013.13010126","article-title":"Gray matter volume as an intermediate phenotype for psychosis: Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP)","volume":"170","author":"Ivleva","year":"2013","journal-title":"Am J Psychiatry"},{"issue":"2","key":"10.1016\/j.jpsychires.2014.12.008_bib34","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/sj.mp.4000494","article-title":"Anti-bipolar therapy: mechanism of action of lithium","volume":"4","author":"Jope","year":"1999","journal-title":"Mol Psychiatry"},{"issue":"4","key":"10.1016\/j.jpsychires.2014.12.008_bib35","first-page":"248","article-title":"Choline-containing compounds detected by proton magnetic resonance spectroscopy in the basal ganglia in bipolar disorder","volume":"21","author":"Kato","year":"1996","journal-title":"J\u00a0Psychiatr Neurosci"},{"issue":"2","key":"10.1016\/j.jpsychires.2014.12.008_bib36","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/schbul\/13.2.261","article-title":"The positive and negative syndrome scale (PANSS) for schizophrenia","volume":"13","author":"Kay","year":"1987","journal-title":"Schizophr Bull"},{"issue":"2\u20133","key":"10.1016\/j.jpsychires.2014.12.008_bib37","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.schres.2003.09.011","article-title":"The brief assessment of cognition in Schizophrenia: reliability, sensitivity, and comparison with a standard neurocognitive battery","volume":"68","author":"Keefe","year":"2004","journal-title":"Schizophr Res"},{"issue":"7","key":"10.1016\/j.jpsychires.2014.12.008_bib38","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1001\/archgenpsychiatry.2011.60","article-title":"Structural neuroimaging studies in major depressive disorder. Meta-analysis and comparison with bipolar disorder","volume":"68","author":"Kempton","year":"2011","journal-title":"Arch Gen Psychiatry"},{"issue":"6","key":"10.1016\/j.jpsychires.2014.12.008_bib39","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1001\/archpsyc.62.6.617","article-title":"Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication","volume":"62","author":"Kessler","year":"2005","journal-title":"Arch Gen Psychiatry"},{"issue":"16","key":"10.1016\/j.jpsychires.2014.12.008_bib40","doi-asserted-by":"crossref","first-page":"8455","DOI":"10.1073\/pnas.93.16.8455","article-title":"A\u00a0molecular mechanism for the effect of lithium on development","volume":"93","author":"Klein","year":"1996","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5","key":"10.1016\/j.jpsychires.2014.12.008_bib41","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1038\/nn.2303","article-title":"Circular analysis in systems neuroscience: the dangers of double dipping","volume":"12","author":"Kriegeskorte","year":"2009","journal-title":"Nat Neurosci"},{"issue":"1","key":"10.1016\/j.jpsychires.2014.12.008_bib42","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1399-5618.2006.00284.x","article-title":"Regional cerebral cortical thinning in bipolar disorder","volume":"8","author":"Lyoo","year":"2006","journal-title":"Bipolar Disord"},{"issue":"S9","key":"10.1016\/j.jpsychires.2014.12.008_bib43","first-page":"82","article-title":"Lithium up-regulates the cytoprotective protein Bcl-2 in the CNS in\u00a0vivo: a role for neurotrophic and neuroprotective effects in manic depressive illness","volume":"61","author":"Manji","year":"1999","journal-title":"J\u00a0Clin Psychiatry"},{"issue":"8","key":"10.1016\/j.jpsychires.2014.12.008_bib44","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/S0006-3223(00)00979-3","article-title":"Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic\u2013depressive illness","volume":"48","author":"Manji","year":"2000","journal-title":"Biol Psychiatry"},{"issue":"8","key":"10.1016\/j.jpsychires.2014.12.008_bib45","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1016\/j.pnpbp.2008.08.012","article-title":"Lithium: bipolar disorder and neurodegenerative diseases possible cellular mechanisms of the therapeutic effects of lithium","volume":"32","author":"Marmol","year":"2008","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"issue":"1","key":"10.1016\/j.jpsychires.2014.12.008_bib46","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.schres.2009.10.018","article-title":"Effects of clozapine and olanzapine on cortical thickness in childhood-onset schizophrenia","volume":"116","author":"Mattai","year":"2010","journal-title":"Schizophr Res"},{"issue":"6","key":"10.1016\/j.jpsychires.2014.12.008_bib47","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1111\/j.1528-1157.1993.tb02123.x","article-title":"Circuit mechanisms of seizures in the pilocarpine model of chronic epilepsy: cell loss and mossy fiber sprouting","volume":"34","author":"Mello","year":"1993","journal-title":"Epilepsia"},{"issue":"9237","key":"10.1016\/j.jpsychires.2014.12.008_bib48","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1016\/S0140-6736(00)02793-8","article-title":"Lithium-induced increase in human brain grey matter","volume":"356","author":"Moore","year":"2000","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.jpsychires.2014.12.008_bib49","doi-asserted-by":"crossref","first-page":"699","DOI":"10.4088\/JCP.07m03745","article-title":"A\u00a0longitudinal study of the effects of lithium treatment on prefrontal and subgenual prefrontal Gray matter volume in treatment-responsive bipolar disorder patients","volume":"70","author":"Moore","year":"2009","journal-title":"J\u00a0Clin Psychiatry"},{"issue":"6","key":"10.1016\/j.jpsychires.2014.12.008_bib50","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.biopsych.2013.11.018","article-title":"Local gyrification index in probands with psychotic disorders and their first-degree relatives","volume":"76","author":"Nanda","year":"2014","journal-title":"Biol Psychiatry"},{"issue":"5","key":"10.1016\/j.jpsychires.2014.12.008_bib51","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1001\/archpsyc.55.5.433","article-title":"Hippocampal volume reduction in schizophrenia as assessed by magnetic resonance imaging: a meta-analytic study","volume":"55","author":"Nelson","year":"1998","journal-title":"Arch Gen Psychiatry"},{"issue":"9","key":"10.1016\/j.jpsychires.2014.12.008_bib52","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1097\/00001756-199806220-00031","article-title":"Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats","volume":"9","author":"Nonaka","year":"1998","journal-title":"NeuroReport"},{"issue":"5","key":"10.1016\/j.jpsychires.2014.12.008_bib53","doi-asserted-by":"crossref","first-page":"2642","DOI":"10.1073\/pnas.95.5.2642","article-title":"Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx","volume":"95","author":"Nonaka","year":"1998","journal-title":"P\u00a0Natl Acad Sci U. S. A"},{"issue":"2","key":"10.1016\/j.jpsychires.2014.12.008_bib54","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1089\/cap.2007.0088","article-title":"Temporal change in N-acetyl-aspartate concentrations in adolescents with bipolar depression treated with lithium","volume":"18","author":"Patel","year":"2008","journal-title":"J\u00a0Child Adolesc Psychopharmacol"},{"key":"10.1016\/j.jpsychires.2014.12.008_bib55","series-title":"Structured interview for DSM-IV personality: SIDP-IV","author":"Pfohl","year":"1997"},{"issue":"1","key":"10.1016\/j.jpsychires.2014.12.008_bib56","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s00213-006-0354-y","article-title":"Lithium and inositol: effects on brain water homeostasis in the rat","volume":"186","author":"Phatak","year":"2006","journal-title":"Psychopharmacology"},{"issue":"2","key":"10.1016\/j.jpsychires.2014.12.008_bib57","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0304-3940(02)00615-8","article-title":"Increased gray matter volume in lithium-treated bipolar disorder patients","volume":"329","author":"Sassi","year":"2002","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.jpsychires.2014.12.008_bib58","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.jad.2013.04.020","article-title":"A\u00a0longitudinal study of fronto-limbic brain structures in patients with bipolar I disorder during lithium treatment","author":"Selek","year":"2013","journal-title":"J\u00a0Affect Disord"},{"issue":"1","key":"10.1016\/j.jpsychires.2014.12.008_bib59","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.coph.2006.07.005","article-title":"Neurotrophic signaling cascades in the pathophysiology and treatment of bipolar disorder","volume":"7","author":"Shaltiel","year":"2007","journal-title":"Curr Opin Pharmacol"},{"issue":"7","key":"10.1016\/j.jpsychires.2014.12.008_bib60","doi-asserted-by":"crossref","first-page":"3100","DOI":"10.1073\/pnas.97.7.3100","article-title":"BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death","volume":"97","author":"Shimizu","year":"2000","journal-title":"P\u00a0Natl Acad Sci USA"},{"issue":"3","key":"10.1016\/j.jpsychires.2014.12.008_bib61","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1001\/archpsyc.56.3.254","article-title":"Brain magnetic resonance imaging of structural abnormalities in bipolar disorder","volume":"56","author":"Strakowski","year":"1999","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.jpsychires.2014.12.008_bib62","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.biopsych.2004.12.009","article-title":"Hippocampal and ventricular volumes in psychotic and nonpsychotic bipolar patients compared with schizophrenia patients and community control subjects: a pilot study","volume":"57","author":"Strasser","year":"2005","journal-title":"Biol Psychiatry"},{"issue":"11","key":"10.1016\/j.jpsychires.2014.12.008_bib63","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1176\/appi.ajp.2013.12101339","article-title":"Clinical phenotypes of psychosis in the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP)","volume":"170","author":"Tamminga","year":"2013","journal-title":"Am J Psychiatry"},{"issue":"1","key":"10.1016\/j.jpsychires.2014.12.008_bib64","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1586\/ern.11.184","article-title":"Gene-expression studies in understanding the mechanism of action of lithium","volume":"12","author":"Toker","year":"2012","journal-title":"Expert Rev Neurother"},{"issue":"6","key":"10.1016\/j.jpsychires.2014.12.008_bib65","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1002\/hipo.20615","article-title":"Automated segmentation of hippocampal subfields from ultra-high resolution in\u00a0vivo MRI","volume":"19","author":"Van Leemput","year":"2009","journal-title":"Hippocampus"},{"issue":"4","key":"10.1016\/j.jpsychires.2014.12.008_bib66","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1254\/jphs.CRJ05009X","article-title":"Lithium: potential therapeutics against acute brain injuries and chronic neurodegenerative diseases","volume":"99","author":"Wada","year":"2005","journal-title":"J\u00a0Pharm Sci"},{"issue":"11","key":"10.1016\/j.jpsychires.2014.12.008_bib67","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.4088\/JCP.08r04972","article-title":"Effects of lithium on cognitive performance: a meta-analysis","volume":"70","author":"Wingo","year":"2009","journal-title":"J\u00a0Clin Psychiatry"},{"issue":"2","key":"10.1016\/j.jpsychires.2014.12.008_bib68","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/sj.npp.1301405","article-title":"Bilateral hippocampal volume increase in patients with bipolar disorder and short-term lithium treatment","volume":"33","author":"Y\u00fccel","year":"2007","journal-title":"Neuropsychopharmacol"}],"container-title":["Journal of Psychiatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395614003495?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395614003495?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,26]],"date-time":"2018-09-26T19:52:17Z","timestamp":1537991537000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022395614003495"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":68,"alternative-id":["S0022395614003495"],"URL":"https:\/\/doi.org\/10.1016\/j.jpsychires.2014.12.008","relation":{},"ISSN":["0022-3956"],"issn-type":[{"value":"0022-3956","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of lithium on cortical thickness and hippocampal subfield volumes in psychotic bipolar disorder","name":"articletitle","label":"Article Title"},{"value":"Journal of Psychiatric Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpsychires.2014.12.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}