{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T06:26:21Z","timestamp":1780467981552,"version":"3.54.1"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["journalofpsychiatricresearch.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Psychiatric Research"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.jpsychires.2015.09.011","type":"journal-article","created":{"date-parts":[[2015,9,26]],"date-time":"2015-09-26T05:34:02Z","timestamp":1443245642000},"page":"33-40","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":57,"special_numbering":"C","title":["Amygdala response predicts trajectory of symptom reduction during Trauma-Focused Cognitive-Behavioral Therapy among adolescent girls with PTSD"],"prefix":"10.1016","volume":"71","author":[{"given":"Josh M.","family":"Cisler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin A.","family":"Sigel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa L.","family":"Kramer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonet","family":"Smitherman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Vanderzee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joy","family":"Pemberton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clinton D.","family":"Kilts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.jpsychires.2015.09.011_bib1","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.tics.2013.05.005","article-title":"A\u00a0causal model of post-traumatic stress disorder: disentangling predisposed from acquired neural abnormalities","volume":"17","author":"Admon","year":"2013","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.jpsychires.2015.09.011_bib2","first-page":"237","article-title":"Development of a short questionnaire for use in epidemiological studies of depression in children and adolescents","volume":"5","author":"Angold","year":"1995","journal-title":"Int. J. Method Psych."},{"issue":"1","key":"10.1016\/j.jpsychires.2015.09.011_bib3","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.pscychresns.2013.05.001","article-title":"Neural responses during emotional processing before and after cognitive trauma therapy for battered women","volume":"214","author":"Aupperle","year":"2013","journal-title":"Psychiatry Res."},{"issue":"3","key":"10.1016\/j.jpsychires.2015.09.011_bib4","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1007\/s10862-012-9280-y","article-title":"An examination of the latent structure of the difficulties in emotion regulation scale","volume":"34","author":"Bardeen","year":"2012","journal-title":"J.\u00a0Psychopathol. Behav. Assess."},{"key":"10.1016\/j.jpsychires.2015.09.011_bib5","series-title":"Development of the Social Brain in Adolescence","first-page":"111","author":"Blakemore","year":"2012"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib6","series-title":"Receptive One-word Picture Vocabulary Test","author":"Brownell","year":"2000"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib7","series-title":"Amygdala and Ventral Anterior Cingulate Activation Predicts Treatment Response to Cognitive Behaviour Therapy for Post-traumatic Stress Disorder","first-page":"555","author":"Bryant","year":"2008"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib8","series-title":"Enhanced Amygdala and Medial Prefrontal Activation during Nonconscious Processing of Fear in Posttraumatic Stress Disorder: an FMRI Study","first-page":"517","author":"Bryant","year":"2008"},{"issue":"4","key":"10.1016\/j.jpsychires.2015.09.011_bib9","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/j.childyouth.2012.01.003","article-title":"The data behind the dissemination: a systematic review of trauma-focused cognitive behavioral therapy for use with children and youth","volume":"34","author":"Cary","year":"2012","journal-title":"Child. Youth Serv. Rev."},{"key":"10.1016\/j.jpsychires.2015.09.011_bib10","series-title":"Exposure to Interpersonal Violence and Risk for PTSD, Depression, Delinquency, and Binge Drinking Among Adolescents: Data from the NSA-r","first-page":"33","author":"Cisler","year":"2012"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib11","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/j.neuroimage.2013.09.018","article-title":"A\u00a0comparison of statistical methods for detecting context-modulated functional connectivity in fMRI","volume":"84","author":"Cisler","year":"2014","journal-title":"Neuroimage"},{"issue":"1","key":"10.1016\/j.jpsychires.2015.09.011_bib12","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jpsychires.2013.09.013","article-title":"Functional reorganization of neural networks during repeated exposure to the traumatic memory in posttraumatic stress disorder: an exploratory fMRI study","volume":"48","author":"Cisler","year":"2014","journal-title":"J.\u00a0Psychiatr. Res."},{"key":"10.1016\/j.jpsychires.2015.09.011_bib13","series-title":"Practice Parameter for the Assessment and Treatment of Children and Adolescents with Posttraumatic Stress Disorder","first-page":"414","author":"Cohen","year":"2010"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib14","series-title":"A\u00a0Multisite, Randomized Controlled Trial for Children with Sexual Abuse-related PTSD Symptoms","first-page":"393","author":"Cohen","year":"2004"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib15","series-title":"Community Treatment of Posttraumatic Stress Disorder for Children Exposed to Intimate Partner Violence: a Randomized Controlled Trial","first-page":"16","author":"Cohen","year":"2011"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib16","series-title":"Understanding Adolescence as a Period of Social-affective Engagement and Goal Flexibility","first-page":"636","author":"Crone","year":"2012"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib17","series-title":"The Amygdala: Vigilance and Emotion","first-page":"13","author":"Davis","year":"2001"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib18","series-title":"Prediction of Individual Brain Maturity Using FMRI","first-page":"1358","author":"Dosenbach","year":"2010"},{"issue":"2","key":"10.1016\/j.jpsychires.2015.09.011_bib19","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.tics.2010.11.004","article-title":"Emotional processing in anterior cingulate and medial prefrontal cortex","volume":"15","author":"Etkin","year":"2011","journal-title":"Trends Cogn. Sci."},{"issue":"9","key":"10.1016\/j.jpsychires.2015.09.011_bib20","doi-asserted-by":"crossref","first-page":"895","DOI":"10.4088\/JCP.12m08020","article-title":"Inhibitory neural activity predicts response to cognitive-behavioral therapy for posttraumatic stress disorder","volume":"74","author":"Falconer","year":"2013","journal-title":"J.\u00a0Clin. Psychiatry"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib21","series-title":"Neural Responses to Masked Fear Faces: Sex Differences and Trauma Exposure in Posttraumatic Stress Disorder","first-page":"241","author":"Felmingham","year":"2010"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib22","series-title":"Improved Assessment of Significant Activation in Functional Magnetic Resonance Imaging (FMRI): Use of a Cluster-size Threshold","first-page":"636","author":"Forman","year":"1995"},{"issue":"40","key":"10.1016\/j.jpsychires.2015.09.011_bib23","doi-asserted-by":"crossref","first-page":"13435","DOI":"10.1523\/JNEUROSCI.4287-13.2014","article-title":"Impaired contextual modulation of memories in PTSD: an fMRI and psychophysiological study of extinction retention and fear renewal","volume":"34","author":"Garfinkel","year":"2014","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.jpsychires.2015.09.011_bib24","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1023\/B:JOBA.0000007455.08539.94","article-title":"Multidimensional assessment of emotion regulation and dysregulation: development, factor structure, and initial validation of the difficulties in emotion regulation scale","volume":"26","author":"Gratz","year":"2004","journal-title":"J.\u00a0Psychopathol. Behav."},{"issue":"2","key":"10.1016\/j.jpsychires.2015.09.011_bib25","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.neuropharm.2011.02.023","article-title":"Impaired safety signal learning may be a biomarker of PTSD","volume":"62","author":"Jovanovic","year":"2012","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib26","series-title":"Risk Factors for Adolescent Substance Abuse and Dependence: Data from a National Sample","first-page":"19","author":"Kilpatrick","year":"2000"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib27","series-title":"Violence and Risk of PTSD, Major Depression, Substance Abuse\/dependence, and Comorbidity: Results from the National Survey of Adolescents","first-page":"692","author":"Kilpatrick","year":"2003"},{"issue":"1","key":"10.1016\/j.jpsychires.2015.09.011_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.pscychresns.2014.04.005","article-title":"Attenuated behavioral and brain responses to trust violations among assaulted adolescent girls","volume":"223","author":"Lenow","year":"2014","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jpsychires.2015.09.011_bib29","series-title":"Investigations of HPA Function and the Enduring Consequences of Stressors in Adolescence in Animal Models","first-page":"73","author":"McCormick","year":"2010"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib30","series-title":"A\u00a0Generalized Form of Context-dependent Psychophysiological Interactions (GPPI): a Comparison to Standard Approaches","first-page":"1277","author":"McLaren","year":"2012"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib31","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.brat.2011.06.003","article-title":"Emotion dysregulation and adolescent psychopathology: a prospective study","volume":"49","author":"McLaughlin","year":"2011","journal-title":"Behav. Res. Ther."},{"issue":"8","key":"10.1016\/j.jpsychires.2015.09.011_bib32","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1016\/j.psyneuen.2012.01.002","article-title":"Sex differences in physiological reactivity to acute psychosocial stress in adolescence","volume":"37","author":"Ordaz","year":"2012","journal-title":"Psychoneuroendocrinology"},{"issue":"9","key":"10.1016\/j.jpsychires.2015.09.011_bib33","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1016\/j.neubiorev.2012.06.003","article-title":"Neurocircuitry models of posttraumatic stress disorder and beyond: a meta-analysis of functional neuroimaging studies","volume":"36","author":"Patel","year":"2012","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"12","key":"10.1016\/j.jpsychires.2015.09.011_bib34","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1038\/nrn2513","article-title":"Why do many psychiatric disorders emerge during adolescence?","volume":"9","author":"Paus","year":"2008","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.jpsychires.2015.09.011_bib35","series-title":"Neurocircuitry Models of Posttraumatic Stress Disorder and Extinction: Human Neuroimaging Research\u2013past, Present, and Future","first-page":"376","author":"Rauch","year":"2006"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib36","series-title":"Exaggerated Amygdala Response to Masked Facial Stimuli in Posttraumatic Stress Disorder: a Functional MRI Study","first-page":"769","author":"Rauch","year":"2000"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib37","series-title":"The Integration of Negative Affect, Pain and Cognitive Control in the Cingulate Cortex","first-page":"154","author":"Shackman","year":"2011"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib38","series-title":"Reliability and Validity of the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-kid)","first-page":"313","author":"Sheehan","year":"2010"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib39","series-title":"The University of California at Los Angeles Post-traumatic Stress Disorder Reaction Index","first-page":"96","author":"Steinberg","year":"2004"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib40","doi-asserted-by":"crossref","first-page":"4415","DOI":"10.1523\/JNEUROSCI.3215-05.2006","article-title":"Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults","volume":"26","author":"Urry","year":"2006","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.jpsychires.2015.09.011_bib41","series-title":"Increased Sensitivity in Neuroimaging Analyses Using Robust Regression","first-page":"99","author":"Wager","year":"2005"},{"key":"10.1016\/j.jpsychires.2015.09.011_bib42","series-title":"Amygdala-prefrontal Dissociation of Subliminal and Supraliminal Fear","first-page":"652","author":"Williams","year":"2006"},{"issue":"3","key":"10.1016\/j.jpsychires.2015.09.011_bib43","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/j.neuroimage.2005.08.006","article-title":"Human striatal activation reflects degree of stimulus saliency","volume":"29","author":"Zink","year":"2006","journal-title":"Neuroimage"},{"issue":"22","key":"10.1016\/j.jpsychires.2015.09.011_bib44","doi-asserted-by":"crossref","first-page":"8092","DOI":"10.1523\/JNEUROSCI.23-22-08092.2003","article-title":"Human striatal response to salient nonrewarding stimuli","volume":"23","author":"Zink","year":"2003","journal-title":"J.\u00a0Neurosci."},{"issue":"3","key":"10.1016\/j.jpsychires.2015.09.011_bib45","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S0896-6273(04)00183-7","article-title":"Human striatal responses to monetary reward depend on saliency","volume":"42","author":"Zink","year":"2004","journal-title":"Neuron"}],"container-title":["Journal of Psychiatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395615002721?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395615002721?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,30]],"date-time":"2019-08-30T20:52:33Z","timestamp":1567198353000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022395615002721"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":45,"alternative-id":["S0022395615002721"],"URL":"https:\/\/doi.org\/10.1016\/j.jpsychires.2015.09.011","relation":{},"ISSN":["0022-3956"],"issn-type":[{"value":"0022-3956","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Amygdala response predicts trajectory of symptom reduction during Trauma-Focused Cognitive-Behavioral Therapy among adolescent girls with PTSD","name":"articletitle","label":"Article Title"},{"value":"Journal of Psychiatric Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpsychires.2015.09.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}