{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:17:48Z","timestamp":1790835468154,"version":"4.1.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Newcastle Healthcare Charity","award":["BH0070250"],"award-info":[{"award-number":["BH0070250"]}]},{"DOI":"10.13039\/501100000691","name":"Academy of Medical Sciences","doi-asserted-by":"publisher","award":["BH090112"],"award-info":[{"award-number":["BH090112"]}],"id":[{"id":"10.13039\/501100000691","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Wellcome Trust Starter Grants scheme for Clinical Lecturers"},{"name":"Wellcome Intermediate Clinical Fellowship","award":["BH083281"],"award-info":[{"award-number":["BH083281"]}]}],"content-domain":{"domain":["journalofpsychiatricresearch.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Psychiatric Research"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1016\/j.jpsychires.2016.03.010","type":"journal-article","created":{"date-parts":[[2016,3,25]],"date-time":"2016-03-25T23:02:10Z","timestamp":1458946930000},"page":"48-55","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"special_numbering":"C","title":["Multimodal EEG-MRI in the differential diagnosis of Alzheimer's disease and dementia with Lewy bodies"],"prefix":"10.1016","volume":"78","author":[{"given":"Sean J.","family":"Colloby","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth A.","family":"Cromarty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis R.","family":"Peraza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristinn","family":"Johnsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00edsli","family":"J\u00f3hannesson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Bonanni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Onofrj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Barber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John T.","family":"O'Brien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John-Paul","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpsychires.2016.03.010_bib1","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1159\/000160962","article-title":"Electroencephalogram variability in dementia with lewy bodies, Alzheimer's disease and controls","volume":"26","author":"Andersson","year":"2008","journal-title":"Dement. Geriatr. Cogn. Disord."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib2","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1212\/WNL.52.6.1153","article-title":"Medial temporal lobe atrophy on MRI in dementia with Lewy bodies","volume":"52","author":"Barber","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib3","doi-asserted-by":"crossref","first-page":"3182","DOI":"10.1161\/STROKEAHA.107.490102","article-title":"The contribution of medial temporal lobe atrophy and vascular pathology to cognitive impairment in vascular dementia","volume":"38","author":"Bastos-Leite","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib4","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1093\/brain\/awm322","article-title":"EEG comparisons in early Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease with dementia patients with a 2-year follow-up","volume":"131","author":"Bonanni","year":"2008","journal-title":"Brain"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib5","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/0013-4694(88)90206-4","article-title":"Diagnostic efficacy of computerized spectral versus visual EEG analysis in elderly normal, demented and depressed subjects","volume":"69","author":"Brenner","year":"1988","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib6","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1093\/brain\/awn298","article-title":"Medial temporal lobe atrophy on MRI differentiates Alzheimer's disease from dementia with Lewy bodies and vascular cognitive impairment: a prospective study with pathological verification of diagnosis","volume":"132","author":"Burton","year":"2009","journal-title":"Brain"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib7","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1006\/nimg.2002.1197","article-title":"Patterns of cerebral atrophy in dementia with Lewy bodies using voxel-based morphometry","volume":"17","author":"Burton","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib8","first-page":"1","article-title":"A\u00a0comparison of 99mTc-exametazime and 123I-FP-CIT SPECT imaging in the differential diagnosis of Alzheimer's disease and dementia with Lewy bodies","author":"Colloby","year":"2008","journal-title":"Int. Psychogeriatr."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib9","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1212\/WNL.44.12.2308","article-title":"The Neuropsychiatric inventory: comprehensive assessment of psychopathology in dementia","volume":"44","author":"Cummings","year":"1994","journal-title":"Neurology"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib10","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/S1474-4422(07)70178-3","article-title":"Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria","volume":"6","author":"Dubois","year":"2007","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000381016","article-title":"Quantitative EEG applying the statistical recognition pattern method: a useful tool in dementia diagnostic workup","volume":"40","author":"Engedal","year":"2015","journal-title":"Dement. Geriatr. Cogn. Disord."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib12","series-title":"Recent Development in Parkinson's Disease","first-page":"153","article-title":"Unified Parkinson's disease rating scale","author":"Fahn","year":"1987"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib13","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"Mini-mental state. A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J.\u00a0Psychiatric Res."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib14","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/s11910-001-0103-x","article-title":"Lewy bodies and dementia","volume":"1","author":"Galasko","year":"2001","journal-title":"Curr. Neurol. Neurosci. Rep."},{"issue":"Suppl.\u00a01","key":"10.1016\/j.jpsychires.2016.03.010_bib15","doi-asserted-by":"crossref","first-page":"S95","DOI":"10.1016\/j.expneurol.2004.06.017","article-title":"Differentiation of Alzheimer's disease from dementia with Lewy bodies utilizing positron emission tomography with [18F]fluorodeoxyglucose and neuropsychological testing","volume":"191","author":"Gilman","year":"2005","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib16","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1007\/s00259-005-1921-x","article-title":"Comparative value of brain perfusion SPECT and [(123)I]MIBG myocardial scintigraphy in distinguishing between dementia with Lewy bodies and Alzheimer's disease","volume":"33","author":"Hanyu","year":"2006","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib17","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.jns.2006.07.007","article-title":"Differentiation of dementia with Lewy bodies from Alzheimer's disease using mini-mental state examination and brain perfusion SPECT","volume":"250","author":"Hanyu","year":"2006","journal-title":"J.\u00a0Neurol. Sci."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib18","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1007\/s12149-014-0873-2","article-title":"Comparison of (123)I-MIBG myocardial scintigraphy, brain perfusion SPECT, and voxel-based MRI morphometry for distinguishing between dementia with Lewy bodies and Alzheimer's disease","volume":"28","author":"Inui","year":"2014","journal-title":"Ann. Nucl. Med."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib19","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1212\/WNL.51.1.125","article-title":"Regional cerebral glucose metabolism in dementia with Lewy bodies and Alzheimer's disease","volume":"51","author":"Ishii","year":"1998","journal-title":"Neurology"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib20","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/S1053-8119(03)00041-7","article-title":"A\u00a0comprehensive study of gray matter loss in patients with Alzheimer's disease using optimized voxel-based morphometry","volume":"18","author":"Karas","year":"2003","journal-title":"Neuroimage"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib21","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1016\/j.clinph.2014.11.021","article-title":"The EEG as a diagnostic tool in distinguishing between dementia with Lewy bodies and Alzheimer's disease","volume":"126","author":"Lee","year":"2015","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib22","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1212\/WNL.56.5.643","article-title":"Occipital hypoperfusion on SPECT in dementia with Lewy bodies but not AD","volume":"56","author":"Lobotesis","year":"2001","journal-title":"Neurology"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib23","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1212\/01.wnl.0000187889.17253.b1","article-title":"Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium","volume":"65","author":"McKeith","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib24","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1192\/bjp.165.3.324","article-title":"The clinical diagnosis and misdiagnosis of senile dementia of Lewy body type (SDLT)","volume":"165","author":"McKeith","year":"1994","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib25","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1212\/WNL.34.7.939","article-title":"Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on alzheimer's disease","volume":"34","author":"McKhann","year":"1984","journal-title":"Neurology"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib26","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jalz.2011.03.005","article-title":"The diagnosis of dementia due to Alzheimer's disease: recommendations from the National institute on aging-Alzheimer's association workgroups on diagnostic guidelines for Alzheimer's disease","volume":"7","author":"McKhann","year":"2011","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib27","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/ana.1133","article-title":"Alzheimer's disease versus dementia with Lewy bodies: cerebral metabolic distinction with autopsy confirmation","volume":"50","author":"Minoshima","year":"2001","journal-title":"Ann. Neurology"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib28","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1017\/S1041610212001214","article-title":"Does posterior cortical atrophy on MRI discriminate between Alzheimer's disease, dementia with Lewy bodies, and normal aging?","volume":"25","author":"O'Donovan","year":"2013","journal-title":"Int. Psychogeriatr."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib29","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/S1388-2457(00)00527-7","article-title":"The five percent electrode system for high-resolution EEG and ERP measurements","volume":"112","author":"Oostenveld","year":"2001","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib30","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1007\/s00259-002-0919-x","article-title":"Value of (99m)Tc-ECD SPET for the diagnosis of dementia with Lewy bodies","volume":"29","author":"Pasquier","year":"2002","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib31","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1136\/jnnp.2007.125385","article-title":"The use of EEG in the diagnosis of dementia with Lewy bodies","volume":"79","author":"Roks","year":"2008","journal-title":"J.\u00a0Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib32","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1136\/jnnp.55.10.967","article-title":"Atrophy of medial temporal lobes on mri in probable alzheimers- disease and normal aging - diagnostic-value and neuropsychological correlates","volume":"55","author":"Scheltens","year":"1992","journal-title":"J.\u00a0Neurology Neurosurg. Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib33","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000085070","article-title":"Differentiation of dementia with Lewy bodies from Alzheimer's disease using brain SPECT","volume":"20","author":"Shimizu","year":"2005","journal-title":"Dement. Geriatr. Cogn. Disord."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib34","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1007\/s00259-015-3146-y","article-title":"Utility of the combination of DAT SPECT and MIBG myocardial scintigraphy in differentiating dementia with Lewy bodies from Alzheimer's disease","volume":"43","author":"Shimizu","year":"2016","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib35","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1159\/000339996","article-title":"Diagnostic accuracy of statistical pattern recognition of electroencephalogram registration in evaluation of cognitive impairment and dementia","volume":"34","author":"Snaedal","year":"2012","journal-title":"Dement. Geriatr. Cogn. Disord."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib36","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.3174\/ajnr.A2200","article-title":"Measurement of gray and white matter atrophy in dementia with Lewy bodies using diffeomorphic anatomic registration through exponentiated lie algebra: a comparison with conventional voxel-based morphometry","volume":"31","author":"Takahashi","year":"2010","journal-title":"AJNR. Am. J. Neuroradiol."},{"key":"10.1016\/j.jpsychires.2016.03.010_bib37","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/j.1552-6569.2010.00532.x","article-title":"Diagnostic performance of myocardial innervation imaging using MIBG scintigraphy in differential diagnosis between dementia with lewy bodies and other dementias: a systematic review and a meta-analysis","volume":"22","author":"Treglia","year":"2012","journal-title":"J.\u00a0Neuroimaging"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib38","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1192\/bjp.177.3.252","article-title":"The clinician assessment of fluctuation and the one day fluctuation assessment scale. Two methods to assess fluctuating confusion in dementia","volume":"177","author":"Walker","year":"2000","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib39","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1136\/jnnp.2006.110122","article-title":"Dementia with Lewy bodies: a comparison of clinical diagnosis, FP-CIT single photon emission computed tomography imaging and autopsy","volume":"78","author":"Walker","year":"2007","journal-title":"J.\u00a0Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib40","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1017\/S1041610211002171","article-title":"Patterns of gray matter atrophy in dementia with Lewy bodies: a voxel-based morphometry study","volume":"24","author":"Watson","year":"2012","journal-title":"Int. Psychogeriatrics"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib41","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1093\/brain\/awl388","article-title":"Focal atrophy in dementia with Lewy bodies on MRI: a distinct pattern from Alzheimer's disease","volume":"130","author":"Whitwell","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.jpsychires.2016.03.010_bib42","doi-asserted-by":"crossref","first-page":"e0120540","DOI":"10.1371\/journal.pone.0120540","article-title":"Diagnostic accuracy of 123I-meta-iodobenzylguanidine myocardial scintigraphy in dementia with Lewy bodies: a multicenter study","volume":"10","author":"Yoshita","year":"2015","journal-title":"PLoS One"}],"container-title":["Journal of Psychiatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395616300486?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395616300486?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,13]],"date-time":"2018-09-13T22:27:29Z","timestamp":1536877649000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022395616300486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":42,"alternative-id":["S0022395616300486"],"URL":"https:\/\/doi.org\/10.1016\/j.jpsychires.2016.03.010","relation":{},"ISSN":["0022-3956"],"issn-type":[{"value":"0022-3956","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multimodal EEG-MRI in the differential diagnosis of Alzheimer's disease and dementia with Lewy bodies","name":"articletitle","label":"Article Title"},{"value":"Journal of Psychiatric Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpsychires.2016.03.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}