{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T18:48:03Z","timestamp":1789843683594,"version":"4.0.1"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["journalofpsychiatricresearch.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Psychiatric Research"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1016\/j.jpsychires.2016.12.012","type":"journal-article","created":{"date-parts":[[2016,12,22]],"date-time":"2016-12-22T18:32:24Z","timestamp":1482431544000},"page":"18-27","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["Olanzapine and aripiprazole differentially affect glucose uptake and energy metabolism in human mononuclear blood cells"],"prefix":"10.1016","volume":"88","author":[{"given":"Britta","family":"Stapel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Kotsiari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela","family":"Scherr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise","family":"Hilfiker-Kleiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Bleich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helge","family":"Frieling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai G.","family":"Kahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpsychires.2016.12.012_bib1","doi-asserted-by":"crossref","first-page":"433","DOI":"10.2174\/18715281113129990041","article-title":"Investigation of 5-HT3A receptor gene expression in peripheral blood mononuclear cells of individuals who had been exposed to air pollution","volume":"12","author":"Ahangari","year":"2013","journal-title":"Inflamm. Allergy Drug Targets"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib2","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/S0006-8993(01)03026-8","article-title":"Inhibition of glucose transport in PC12 cells by the atypical antipsychotic drugs risperidone and clozapine, and structural analogs of clozapine","volume":"923","author":"Ardizzone","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib3","doi-asserted-by":"crossref","first-page":"231","DOI":"10.3109\/08039488.2015.1074285","article-title":"Treatment of adult patients with schizophrenia and complex mental health needs - a national clinical guideline","volume":"70","author":"Baandrup","year":"2016","journal-title":"Nord. J. Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib4","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.fob.2015.04.006","article-title":"Antipsychotics inhibit glucose transport: determination of olanzapine binding site in Staphylococcus epidermidis glucose\/H(+) symporter","volume":"5","author":"Babkin","year":"2015","journal-title":"FEBS Open Bio"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib5","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.schres.2007.03.029","article-title":"Metformin as an adjunctive treatment to control body weight and metabolic dysfunction during olanzapine administration: a multicentric, double-blind, placebo-controlled trial","volume":"93","author":"Baptista","year":"2007","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib6","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1146\/annurev.nu.13.070193.002433","article-title":"Regulation of the pyruvate dehydrogenase multienzyme complex","volume":"13","author":"Behal","year":"1993","journal-title":"Annu. Rev. Nutr."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib7","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.2337\/diabetes.53.4.1052","article-title":"Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions?","volume":"53","author":"Brunmair","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib8","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3109\/15622975.2011.592546","article-title":"Can an early weight management program (WMP) prevent olanzapine (OLZ)-induced disturbances in body weight, blood glucose and lipid metabolism? Twenty-four- and 48-week results from a 6-month randomized trial","volume":"15","author":"Cordes","year":"2014","journal-title":"World J. Biol. Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib9","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/wps.20204","article-title":"Effects of antipsychotics, antidepressants and mood stabilizers on risk for physical diseases in people with schizophrenia, depression and bipolar disorder","volume":"14","author":"Correll","year":"2015","journal-title":"World Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib10","first-page":"241","article-title":"AMPK activation: a therapeutic target for type 2 diabetes?","volume":"7","author":"Coughlan","year":"2014","journal-title":"Diabetes Metab. Syndr. Obes."},{"issue":"Pt 3","key":"10.1016\/j.jpsychires.2016.12.012_bib11","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1042\/bj20021812","article-title":"Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression","volume":"371","author":"da Silva Xavier","year":"2003","journal-title":"Biochem. J."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib12","doi-asserted-by":"crossref","first-page":"227","DOI":"10.2337\/diab.41.2.227","article-title":"Insulin-stimulated glucose transport in circulating mononuclear cells from nondiabetic and IDDM subjects","volume":"41","author":"Daneman","year":"1992","journal-title":"Diabetes"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib13","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.eurpsy.2009.01.005","article-title":"Cardiovascular disease and diabetes in people with severe mental illness position statement from the European psychiatric association (EPA), supported by the European association for the study of diabetes (EASD) and the European Society of Cardiology (ESC)","volume":"24","author":"De Hert","year":"2009","journal-title":"Eur. Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib14","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0278-5846(98)00092-X","article-title":"Antipsychotic drugs affect glucose uptake and the expression of glucose transporters in PC12 cells","volume":"23","author":"Dwyer","year":"1999","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib15","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.4088\/JCP.09m05274yel","article-title":"The effect of metformin on anthropometrics and insulin resistance in patients receiving atypical antipsychotic agents: a meta-analysis","volume":"71","author":"Ehret","year":"2010","journal-title":"J.\u00a0Clin. Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib16","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1111\/j.1525-1497.2004.40126.x","article-title":"Weight gain and new onset diabetes associated with olanzapine and risperidone","volume":"19","author":"Farwell","year":"2004","journal-title":"J.\u00a0Gen. Int. Med."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib17","doi-asserted-by":"crossref","first-page":"e20571","DOI":"10.1371\/journal.pone.0020571","article-title":"Olanzapine-induced hyperphygia and weight gain associate with orexigenic hypothalamic neuropeptide signaling without comcomitant AMPK phosphorylation","volume":"6","author":"Fern\u00f8","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib18","first-page":"106","article-title":"Increased food intake and energy expenditure following administration of olanzapine to healthy men","volume":"30","author":"Fountaine","year":"2010","journal-title":"Obes. (Silver Spring)"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib19","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1038\/oby.2010.6","article-title":"Increased food intake and energy expenditure following administration of olanzapine to healthy men","volume":"18","author":"Fountaine","year":"2010","journal-title":"Obesity"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib20","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1001\/jamapsychiatry.2015.2923","article-title":"Type 2 diabetes mellitus in youth exposed to antipsychotics: a systematic review and meta-analysis","volume":"73","author":"Galling","year":"2016","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib21","doi-asserted-by":"crossref","first-page":"920","DOI":"10.4088\/JCP.v63n1010","article-title":"Differential effects of risperidone, olanzapine, clozapine, and conventional antipsychotics on type 2 diabetes: findings from a large health plan database","volume":"63","author":"Gianfrancesco","year":"2002","journal-title":"J.\u00a0Clin. Psychiatry"},{"issue":"Suppl.\u00a04","key":"10.1016\/j.jpsychires.2016.12.012_bib22","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1038\/ijo.2008.116","article-title":"AMPK: a key regulator of energy balance in the single cell and the whole organism","volume":"32","author":"Hardie","year":"2008","journal-title":"Int. J. Obes."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib23","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/472176a","article-title":"Signal transduction: how cells sense energy","volume":"472","author":"Hardie","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib24","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0065-2571(01)00061-9","article-title":"Regulation of the activity of the pyruvate dehydrogenase complex","volume":"42","author":"Harris","year":"2002","journal-title":"Advan Enzyme Regul."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib25","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.jpsychires.2005.04.016","article-title":"Effects of different antipsychotics and the antidepressant mirtazapine on glucose transporter mRNA levels in human blood cells","volume":"40","author":"Heiser","year":"2006","journal-title":"J.\u00a0Psych. Res."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib26","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/S2215-0366(15)00115-7","article-title":"Pathophysiological mechanisms of increased cardiometabolic risk in people with schizophrenia and severe mental illnesses","volume":"2","author":"Henderson","year":"2015","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib27","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1177\/0269881105056647","article-title":"Early effects of olanzapine on serum levels of ghrelin, adiponectin and leptin in patients with schizophrenia","volume":"20","author":"Hosojima","year":"2006","journal-title":"J.\u00a0Psychopharmacol."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib28","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/0092-8674(89)90605-3","article-title":"Molecular cloning and characterization of a human DNA binding factor that represses transcription","volume":"59","author":"Kageyama","year":"1989","journal-title":"Cell."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib29","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.jpsychires.2016.02.002","article-title":"Altered DNA methylation of glucose transporter 1 and glucose transporter 4 in patients with major depressive disorder","volume":"76","author":"Kahl","year":"2016","journal-title":"J.\u00a0Psych. Res."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib30","doi-asserted-by":"crossref","first-page":"547","DOI":"10.4088\/JCP.v67n0405","article-title":"Weight management program for treatment-emergent weight gain in olanzapine-treated patients with schizophrenia or schizoaffective disorder: a 12-week randomized controlled clinical trial","volume":"67","author":"Kwon","year":"2006","journal-title":"J.\u00a0Clin. Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib31","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1093\/aje\/kwj289","article-title":"Diabetes risk associated with use of olanzapine, quetiapine, and risperidone in veterans health administration patients with schizophrenia","volume":"164","author":"Lambert","year":"2006","journal-title":"Am. J. Epidemiol."},{"issue":"2 Suppl","key":"10.1016\/j.jpsychires.2016.12.012_bib32","first-page":"1","article-title":"Practice guideline for the treatment of patients with schizophrenia, second ed","volume":"161","author":"Lehman","year":"2004","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib33","doi-asserted-by":"crossref","first-page":"e0147483","DOI":"10.1371\/journal.pone.0147483","article-title":"Dopaminergic receptors and tyrosine hydroxylase expression in peripheral blood mononuclear cells: a distinct pattern in central obesity","volume":"11","author":"Leite","year":"2016","journal-title":"PloS One"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib34","doi-asserted-by":"crossref","first-page":"3005","DOI":"10.1093\/bioinformatics\/bth346","article-title":"Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates","volume":"20","author":"Lewin","year":"2004","journal-title":"Bioinformatics"},{"issue":"22","key":"10.1016\/j.jpsychires.2016.12.012_bib35","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.3923\/pjbs.2013.1459.1468","article-title":"Advances in the research of AMPK and its subunit genes","volume":"16","author":"Liu","year":"2013","journal-title":"Pak J. Biol. Sci."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib36","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1111\/j.1365-2362.2007.01786.x","article-title":"Glucose transporter expression on the plasma membrane of resting and activated white blood cells","volume":"37","author":"Maratou","year":"2007","journal-title":"Eur. J. Clin. Invest"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib37","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1093\/bioinformatics\/18.2.333","article-title":"PROMO: detection of known transcription regulatory elements using species-tailored searches","volume":"18","author":"Messeguer","year":"2002","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib38","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1038\/sj.mp.4001948","article-title":"Alterations of lipid metabolism and gene expression in rat adipocytes during chronic olanzapine treatment","volume":"12","author":"Minet-Ringuet","year":"2007","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib39","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1016\/j.intimp.2004.05.001","article-title":"Differential cAMP levels and serotonin effects in blood peripheral mononuclear cells and lymphocytes from major depression patients","volume":"4","author":"Mizrahi","year":"2004","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib40","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/S1097-2765(01)00251-9","article-title":"A\u00a0role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle","volume":"7","author":"Mu","year":"2001","journal-title":"Mol. Cell."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib41","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1016\/j.lfs.2007.01.010","article-title":"The non-neuronal cholinergic system in peripheral blood cells: effects of nicotinic and muscarinic receptor antagonists on phagocytosis, respiratory burst and migration","volume":"80","author":"Neumann","year":"2007","journal-title":"Life Sci."},{"issue":"Suppl.\u00a01","key":"10.1016\/j.jpsychires.2016.12.012_bib42","first-page":"1","article-title":"Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review","volume":"19","author":"Newcomer","year":"2005","journal-title":"CNS Drugs"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib43","doi-asserted-by":"crossref","first-page":"16092","DOI":"10.1073\/pnas.1105062108","article-title":"AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise","volume":"108","author":"O'Neill","year":"2011","journal-title":"Proc. Nat. Acad. Sci. U. S. A."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib44","doi-asserted-by":"crossref","first-page":"509","DOI":"10.4088\/JCP.v67n0401","article-title":"Atypical antipsychotics in the treatment of mania: a meta-analysis of randomized, placebo-controlled trials","volume":"67","author":"Perlis","year":"2006","journal-title":"J.\u00a0Clin. Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib45","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/nar\/29.9.e45","article-title":"A\u00a0new mathematical model for relative quantification in real-time RT-PCR","volume":"29","author":"Pfaffl","year":"2001","journal-title":"Nucl. Acids Res."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib46","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.1365-2125.2010.03783.x","article-title":"Metformin for olanzapine-induced weight gain: a systematic review and meta-analysis","volume":"71","author":"Praharaj","year":"2011","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib47","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1097\/JCP.0000000000000469","article-title":"A\u00a0naturalistic randomized placebo-controlled trial of extended-release metformin to prevent weight gain associated with olanzapine in a US community-dwelling population","volume":"36","author":"Rado","year":"2016","journal-title":"J.\u00a0Clin. Psychopharmacol."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib48","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1038\/sj.emboj.7600667","article-title":"Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction","volume":"24","author":"Sakamoto","year":"2005","journal-title":"EMBO J."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib49","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1093\/schbul\/sbm141","article-title":"Leptin and ghrein levels in patients with schizophrenia during different antipsychotics treatment: a review","volume":"34","author":"Sentissi","year":"2008","journal-title":"Schizoph Bull."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib50","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1097\/JCP.0b013e3182524393","article-title":"Dysregulation of adipocytokines related to second-generation antipsychotics in normal fasting glucose patients with schizophrenia","volume":"30","author":"Sugai","year":"2012","journal-title":"J.\u00a0Clin. Psychopharmacol."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib51","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.jad.2010.11.009","article-title":"Comparative efficacy and acceptability of mood stabilizer and second generation antipsychotic monotherapy for acute mania\u2013a systematic review and meta-analysis","volume":"134","author":"Tarr","year":"2011","journal-title":"J.\u00a0Affect. Disord."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib52","doi-asserted-by":"crossref","first-page":"3228","DOI":"10.2174\/092986708786848451","article-title":"(Neuro)transmitter systems in circulating immune cells: a target of immunopharmacological interventions?","volume":"15","author":"Tayebati","year":"2008","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib54","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.psychres.2012.09.026","article-title":"Relationships between physical fitness, physical activity, smoking and metabolic and mental health parameters in people with schizophrenia","volume":"207","author":"Vancampfort","year":"2013","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib55","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1002\/wps.20252","article-title":"Risk of metabolic syndrome and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder: a systematic review and meta-analysis","volume":"14","author":"Vancampfort","year":"2015","journal-title":"World Psychiatry"},{"issue":"2 Pt 1","key":"10.1016\/j.jpsychires.2016.12.012_bib56","first-page":"E299","article-title":"Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise","volume":"270","author":"Winder","year":"1996","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib57","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1176\/appi.ajp.2007.07010079","article-title":"Metformin addition attenuates olanzapine-induced weight gain in drug-naive first-episode schizophrenia patients: a double-blind, placebo-controlled study","volume":"165","author":"Wu","year":"2008","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.jpsychires.2016.12.012_bib58","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/1471-2105-13-134","article-title":"Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction","volume":"13","author":"Ye","year":"2012","journal-title":"BMC Bioinforma."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib59","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/gtc.12114","article-title":"Identification of a novel component C2ORF3 in the lariat-intron complex: lack of C2ORF3 interferes with pre-mRNA splicing via intron turnover pathway","volume":"19","author":"Yoshimoto","year":"2014","journal-title":"Genes cells.."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib60","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1152\/jappl.2001.91.3.1073","article-title":"Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase","volume":"91","author":"Zheng","year":"2001","journal-title":"J.\u00a0Appl. Physiol."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib61","doi-asserted-by":"crossref","DOI":"10.1093\/ijnp\/pyv060","article-title":"Atypical antipsychotic augmentation for treatment-resistant depression: a systematic review and network meta-analysis","volume":"18","author":"Zhou","year":"2015","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.jpsychires.2016.12.012_bib62","doi-asserted-by":"crossref","first-page":"15983","DOI":"10.1073\/pnas.252625599","article-title":"AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation","volume":"99","author":"Zong","year":"2002","journal-title":"Proc. Nat. Acad. Sci. U. S. A."}],"container-title":["Journal of Psychiatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395616307889?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395616307889?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,16]],"date-time":"2019-09-16T17:27:45Z","timestamp":1568654865000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022395616307889"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":61,"alternative-id":["S0022395616307889"],"URL":"https:\/\/doi.org\/10.1016\/j.jpsychires.2016.12.012","relation":{},"ISSN":["0022-3956"],"issn-type":[{"value":"0022-3956","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Olanzapine and aripiprazole differentially affect glucose uptake and energy metabolism in human mononuclear blood cells","name":"articletitle","label":"Article Title"},{"value":"Journal of Psychiatric Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpsychires.2016.12.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}