{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T22:02:52Z","timestamp":1789164172233,"version":"build-2803163510"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["16dk0307047h0002"],"award-info":[{"award-number":["16dk0307047h0002"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009438","name":"National Center of Neurology and Psychiatry","doi-asserted-by":"publisher","award":["25253075"],"award-info":[{"award-number":["25253075"]}],"id":[{"id":"10.13039\/501100009438","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Psychiatric Research"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.jpsychires.2017.09.014","type":"journal-article","created":{"date-parts":[[2017,9,19]],"date-time":"2017-09-19T22:00:29Z","timestamp":1505858429000},"page":"23-32","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":73,"special_numbering":"C","title":["Plasma amino acid profile in major depressive disorder: Analyses in two independent case-control sample sets"],"prefix":"10.1016","volume":"96","author":[{"given":"Shintaro","family":"Ogawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norie","family":"Koga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kotaro","family":"Hattori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junko","family":"Matsuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miho","family":"Ota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Hori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daimei","family":"Sasayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiya","family":"Teraishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikki","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuyuko","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumiko","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takamasa","family":"Noda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teruhiko","family":"Higuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Kunugi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5 Suppl","key":"10.1016\/j.jpsychires.2017.09.014_bib1","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/0924-977X(95)00033-L","article-title":"Plasma concentrations of excitatory amino acids, serine, glycine, taurine and histidine in major depression","author":"Altamura","year":"1995","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.jpsychires.2017.09.014_bib2","series-title":"Diagnostic and Statistical Manual of Mental Disorders: DSM-IV","author":"American Psychiatric Association","year":"1994"},{"issue":"11","key":"10.1016\/j.jpsychires.2017.09.014_bib3","doi-asserted-by":"crossref","first-page":"3414","DOI":"10.1002\/pmic.200500069","article-title":"Proteomic analysis of the anterior cingulate cortex in the major psychiatric disorders: evidence for disease-associated changes","volume":"6","author":"Beasley","year":"2006","journal-title":"Proteomics"},{"key":"10.1016\/j.jpsychires.2017.09.014_bib4","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1600-0404.1994.tb05404.x","article-title":"S-adenosylmethionine blood levels in major depression: changes with drug treatment","volume":"154","author":"Bell","year":"1994","journal-title":"Acta Neurol. Scand. Suppl."},{"issue":"12","key":"10.1016\/j.jpsychires.2017.09.014_bib5","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1136\/jnnp.53.12.1096","article-title":"Cerebrospinal fluid S-adenosylmethionine in depression and dementia: effects of treatment with parenteral and oral S-adenosylmethionine","volume":"53","author":"Bottiglieri","year":"1990","journal-title":"J.\u00a0Neurol. Neurosurg. Psychiatry"},{"issue":"2","key":"10.1016\/j.jpsychires.2017.09.014_bib6","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1136\/jnnp.69.2.228","article-title":"Homocysteine, folate, methylation, and monoamine metabolism in depression","volume":"69","author":"Bottiglieri","year":"2000","journal-title":"J.\u00a0Neurol. Neurosurg. Psychiatry"},{"issue":"5","key":"10.1016\/j.jpsychires.2017.09.014_bib7","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/nrn3475","article-title":"Power failure: why small sample size undermines the reliability of neuroscience","volume":"14","author":"Button","year":"2013","journal-title":"Nat. Rev. Neurosci."},{"issue":"225","key":"10.1016\/j.jpsychires.2017.09.014_bib8","doi-asserted-by":"crossref","DOI":"10.1126\/stke.2252004re5","article-title":"Life stress, genes, and depression: multiple pathways lead to increased risk and new opportunities for intervention","volume":"2004","author":"Charney","year":"2004","journal-title":"Sci. STKE"},{"issue":"22","key":"10.1016\/j.jpsychires.2017.09.014_bib9","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1002\/1097-0258(20001130)19:22<3127::AID-SIM784>3.0.CO;2-M","article-title":"A\u00a0simple method for converting an odds ratio to effect size for use in meta-analysis","volume":"19","author":"Chinn","year":"2000","journal-title":"Stat. Med."},{"key":"10.1016\/j.jpsychires.2017.09.014_bib10","series-title":"Statistical Power Analysis for the Behavioral Sciences","author":"Cohen","year":"1988"},{"issue":"3","key":"10.1016\/j.jpsychires.2017.09.014_bib11","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.psyneuen.2010.09.012","article-title":"Inflammation-associated depression: from serotonin to kynurenine","volume":"36","author":"Dantzer","year":"2011","journal-title":"Psychoneuroendocrinology"},{"issue":"1","key":"10.1016\/j.jpsychires.2017.09.014_bib12","doi-asserted-by":"crossref","first-page":"35","DOI":"10.2174\/1871527314666150821103825","article-title":"A\u00a0comprehensive review on the efficacy of S-Adenosyl-L-methionine in Major Depressive Disorder","volume":"15","author":"De Berardis","year":"2016","journal-title":"CNS Neurol. Disord. Drug Targets"},{"issue":"6","key":"10.1016\/j.jpsychires.2017.09.014_bib13","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1001\/archpsyc.1981.01780310042003","article-title":"Plasma tryptophan and five other amino acids in depressed and normal subjects","volume":"38","author":"DeMyer","year":"1981","journal-title":"Arch. Gen. Psychiatry"},{"issue":"2","key":"10.1016\/j.jpsychires.2017.09.014_bib14","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.meatsci.2009.08.028","article-title":"Biomarkers of meat intake and the application of nutrigenomics","volume":"84","author":"Dragsted","year":"2010","journal-title":"Meat Sci."},{"issue":"7","key":"10.1016\/j.jpsychires.2017.09.014_bib15","doi-asserted-by":"crossref","first-page":"e69637","DOI":"10.1371\/journal.pone.0069637","article-title":"The epidemiological modelling of major depressive disorder: application for the Global Burden of Disease Study 2010","volume":"8","author":"Ferrari","year":"2013","journal-title":"PLoS One"},{"issue":"10053","key":"10.1016\/j.jpsychires.2017.09.014_bib16","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/S0140-6736(16)31678-6","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015","volume":"388","year":"2016","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.jpsychires.2017.09.014_bib17","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1016\/S0006-291X(83)80029-1","article-title":"Regulation by glucocorticoids of rat-liver phenylalanine hydroxylase in\u00a0vivo","volume":"115","author":"Haggerty","year":"1983","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jpsychires.2017.09.014_bib18","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A\u00a0rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"J.\u00a0Neurol. Neurosurg. Psychiatry"},{"issue":"3","key":"10.1016\/j.jpsychires.2017.09.014_bib19","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/mp.2015.211","article-title":"Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation","volume":"21","author":"Harraz","year":"2016","journal-title":"Mol. Psychiatry"},{"issue":"2","key":"10.1016\/j.jpsychires.2017.09.014_bib20","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.brainresrev.2009.05.005","article-title":"Emerging role of glutamate in the pathophysiology of major depressive disorder","volume":"61","author":"Hashimoto","year":"2009","journal-title":"Brain Res. Rev."},{"issue":"3","key":"10.1016\/j.jpsychires.2017.09.014_bib21","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1017\/neu.2015.59","article-title":"Increased serum levels of serine enantiomers in patients with depression","volume":"28","author":"Hashimoto","year":"2016","journal-title":"Acta Neuropsychiatr."},{"issue":"3","key":"10.1016\/j.jpsychires.2017.09.014_bib22","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/j.2051-5545.2010.tb00298.x","article-title":"Pathophysiology of depression: do we have any solid evidence of interest to clinicians?","volume":"9","author":"Hasler","year":"2010","journal-title":"World Psychiatry"},{"issue":"2\u20133","key":"10.1016\/j.jpsychires.2017.09.014_bib23","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0165-1781(01)00282-7","article-title":"Effect of electroconvulsive therapy on biopterin and large neutral amino acids in severe, medication-resistant depression","volume":"103","author":"Hoekstra","year":"2001","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jpsychires.2017.09.014_bib24","series-title":"Equivalent Dose of Psychotropics","author":"Inagaki","year":"2013"},{"issue":"3","key":"10.1016\/j.jpsychires.2017.09.014_bib25","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1042\/bj1790723","article-title":"Co-ordinate regulation of ethanolamine kinase and phosphoethanolamine cytidylyltransferase in the biosynthesis of phosphatidylethanolamine in rat liver","volume":"179","author":"Infante","year":"1979","journal-title":"Biochem. J."},{"issue":"9","key":"10.1016\/j.jpsychires.2017.09.014_bib26","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1002\/gps.3899","article-title":"Folate metabolism genes, dietary folate and response to antidepressant medications in late-life depression","volume":"28","author":"Jamerson","year":"2013","journal-title":"Int. J. Geriatr. Psychiatry"},{"issue":"4","key":"10.1016\/j.jpsychires.2017.09.014_bib27","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1093\/ije\/dyu273","article-title":"Epigenetics and depressive disorders: a review of current progress and future directions","volume":"44","author":"Januar","year":"2015","journal-title":"Int. J. Epidemiol."},{"issue":"19","key":"10.1016\/j.jpsychires.2017.09.014_bib28","doi-asserted-by":"crossref","first-page":"13110","DOI":"10.1074\/jbc.M601612200","article-title":"Regulation of the Saccharomyces cerevisiae EKI1-encoded ethanolamine kinase by zinc depletion","volume":"281","author":"Kersting","year":"2006","journal-title":"J.\u00a0Biol. Chem."},{"issue":"10","key":"10.1016\/j.jpsychires.2017.09.014_bib29","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1111\/pcn.12299","article-title":"Biochemical markers subtyping major depressive disorder","volume":"69","author":"Kunugi","year":"2015","journal-title":"Psychiatry Clin. Neurosci."},{"issue":"1","key":"10.1016\/j.jpsychires.2017.09.014_bib30","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1038\/sj.npp.1300868","article-title":"Assessment of the dexamethasone\/CRH test as a state-dependent marker for hypothalamic-pituitary-adrenal (HPA) axis abnormalities in major depressive episode: a Multicenter Study","volume":"31","author":"Kunugi","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.jpsychires.2017.09.014_bib31","doi-asserted-by":"crossref","first-page":"16024","DOI":"10.1038\/srep16024","article-title":"Fluoxetine regulates mTOR signalling in a region-dependent manner in depression-like mice","volume":"5","author":"Liu","year":"2015","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.jpsychires.2017.09.014_bib32","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0165-1781(92)90043-3","article-title":"Plasma tryptophan levels and plasma tryptophan\/neutral amino acids ratio in patients with mood disorder, patients with obsessive-compulsive disorder, and normal subjects","volume":"44","author":"Lucca","year":"1992","journal-title":"Psychiatry Res."},{"issue":"1","key":"10.1016\/j.jpsychires.2017.09.014_bib33","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1600-0447.1990.tb06443.x","article-title":"Suppressant effects of dexamethasone on the availability of plasma L-tryptophan and tyrosine in healthy controls and in depressed patients","volume":"81","author":"Maes","year":"1990","journal-title":"Acta Psychiatr. Scand."},{"issue":"4","key":"10.1016\/j.jpsychires.2017.09.014_bib34","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/j.1600-0447.1998.tb10004.x","article-title":"Serum levels of excitatory amino acids, serine, glycine, histidine, threonine, taurine, alanine and arginine in treatment-resistant depression: modulation by treatment with antidepressants and prediction of clinical responsivity","volume":"97","author":"Maes","year":"1998","journal-title":"Acta Psychiatr. Scand."},{"issue":"3","key":"10.1016\/j.jpsychires.2017.09.014_bib35","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1159\/000054933","article-title":"Predictive value of amino acids in the treatment of major depression with fluvoxamine","volume":"44","author":"Mauri","year":"2001","journal-title":"Neuropsychobiology"},{"issue":"3","key":"10.1016\/j.jpsychires.2017.09.014_bib36","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1159\/000026491","article-title":"Plasma and platelet amino acid concentrations in patients affected by major depression and under fluvoxamine treatment","volume":"37","author":"Mauri","year":"1998","journal-title":"Neuropsychobiology"},{"issue":"21","key":"10.1016\/j.jpsychires.2017.09.014_bib37","doi-asserted-by":"crossref","first-page":"14586","DOI":"10.1016\/S0021-9258(18)42081-9","article-title":"Serine regulates phosphatidylethanolamine biosynthesis in the hamster heart","volume":"267","author":"McMaster","year":"1992","journal-title":"J.\u00a0Biol. Chem."},{"issue":"4","key":"10.1016\/j.jpsychires.2017.09.014_bib38","doi-asserted-by":"crossref","first-page":"370","DOI":"10.4088\/JCP.13m08591","article-title":"A\u00a0double-blind, randomized, placebo-controlled clinical trial of S-adenosyl-L-methionine (SAMe) versus escitalopram in major depressive disorder","volume":"75","author":"Mischoulon","year":"2014","journal-title":"J.\u00a0Clin. Psychiatry"},{"issue":"6","key":"10.1016\/j.jpsychires.2017.09.014_bib39","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/j.pnpbp.2006.03.036","article-title":"Correlation between plasma levels of glutamate, alanine and serine with severity of depression","volume":"30","author":"Mitani","year":"2006","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"4","key":"10.1016\/j.jpsychires.2017.09.014_bib40","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0165-0327(93)90046-M","article-title":"Plasma amino acid profiles in relation to clinical response to moclobemide in patients with major depression. Danish University Antidepressant Group","volume":"27","author":"Moller","year":"1993","journal-title":"J.\u00a0Affect Disord."},{"issue":"1","key":"10.1016\/j.jpsychires.2017.09.014_bib41","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.ejphar.2008.10.049","article-title":"Forced swimming and imipramine modify plasma and brain amino acid concentrations in mice","volume":"602","author":"Murakami","year":"2009","journal-title":"Eur. J. Pharmacol."},{"issue":"7","key":"10.1016\/j.jpsychires.2017.09.014_bib42","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1038\/nrd.2017.16","article-title":"Targeting glutamate signalling in depression: progress and prospects","volume":"16","author":"Murrough","year":"2017","journal-title":"Nat. Rev. Drug Discov."},{"issue":"6","key":"10.1016\/j.jpsychires.2017.09.014_bib43","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1007\/s00726-015-1944-y","article-title":"Chronic activation of mTOR complex 1 by branched chain amino acids and organ hypertrophy","volume":"47","author":"Neishabouri","year":"2015","journal-title":"Amino Acids"},{"issue":"9","key":"10.1016\/j.jpsychires.2017.09.014_bib44","doi-asserted-by":"crossref","first-page":"e906","DOI":"10.4088\/JCP.13r08908","article-title":"Plasma L-tryptophan concentration in major depressive disorder: new data and meta-analysis","volume":"75","author":"Ogawa","year":"2014","journal-title":"J.\u00a0Clin. Psychiatry"},{"key":"10.1016\/j.jpsychires.2017.09.014_bib45","doi-asserted-by":"crossref","first-page":"7796","DOI":"10.1038\/srep07796","article-title":"Reduced cerebrospinal fluid ethanolamine concentration in major depressive disorder","volume":"5","author":"Ogawa","year":"2015","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.jpsychires.2017.09.014_bib46","doi-asserted-by":"crossref","first-page":"760","DOI":"10.2174\/1570159X13666150612225212","article-title":"Inhibitors of fatty acid amide hydrolase and monoacylglycerol lipase: new targets for future antidepressants","volume":"13","author":"Ogawa","year":"2015","journal-title":"Curr. Neuropharmacol."},{"issue":"7","key":"10.1016\/j.jpsychires.2017.09.014_bib47","first-page":"1473","article-title":"Comparison of protein precipitants for the determination of free amino acids in plasma","volume":"43","author":"Ohara","year":"1979","journal-title":"Agric. Biol. Chem."},{"issue":"5","key":"10.1016\/j.jpsychires.2017.09.014_bib48","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1111\/j.1440-1819.2005.01408.x","article-title":"Reliability and validity of Japanese version of the mini-international neuropsychiatric interview","volume":"59","author":"Otsubo","year":"2005","journal-title":"Psychiatry Clin. Neurosci."},{"issue":"1","key":"10.1016\/j.jpsychires.2017.09.014_bib49","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0018-506X(02)00016-8","article-title":"Neuroendocrine aspects of hypercortisolism in major depression","volume":"43","author":"Parker","year":"2003","journal-title":"Horm. Behav."},{"key":"10.1016\/j.jpsychires.2017.09.014_bib50","doi-asserted-by":"crossref","first-page":"603","DOI":"10.2147\/DDDT.S62912","article-title":"Altered gamma-aminobutyric acid neurotransmission in major depressive disorder: a critical review of the supporting evidence and the influence of serotonergic antidepressants","volume":"9","author":"Pehrson","year":"2015","journal-title":"Drug Des. Devel Ther."},{"issue":"2","key":"10.1016\/j.jpsychires.2017.09.014_bib51","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jad.2012.02.008","article-title":"Low plasma levels of L-arginine, impaired intraplatelet nitric oxide and platelet hyperaggregability: implications for cardiovascular disease in depressive patients","volume":"140","author":"Pinto","year":"2012","journal-title":"J.\u00a0Affect Disord."},{"issue":"2","key":"10.1016\/j.jpsychires.2017.09.014_bib52","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1073\/pnas.79.2.365","article-title":"Induction of tyrosine aminotransferase mRNA by glucocorticoids and cAMP in fetal rat liver","volume":"79","author":"Ruiz-Bravo","year":"1982","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.jpsychires.2017.09.014_bib53","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0165-0327(90)90003-Q","article-title":"Plasma tryptophan to large neutral amino acid ratios in depressed and normal subjects","volume":"19","author":"Russ","year":"1990","journal-title":"J.\u00a0Affect Disord."},{"issue":"3","key":"10.1016\/j.jpsychires.2017.09.014_bib54","doi-asserted-by":"crossref","first-page":"953","DOI":"10.4141\/cjas91-116","article-title":"Effect of protein precipitating agents on the recovery of plasma free amino acids","volume":"71","author":"Sedgwick","year":"1991","journal-title":"Can. J. Animal Sci."},{"issue":"3","key":"10.1016\/j.jpsychires.2017.09.014_bib55","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/sj.mp.4000485","article-title":"Serotonin transporter gene (5-HTTLPR) is not associated with depressive symptomatology in mood disorders","volume":"4","author":"Serretti","year":"1999","journal-title":"Mol. Psychiatry"},{"issue":"12","key":"10.1016\/j.jpsychires.2017.09.014_bib56","doi-asserted-by":"crossref","first-page":"e0165267","DOI":"10.1371\/journal.pone.0165267","article-title":"Plasma metabolites predict severity of depression and suicidal ideation in psychiatric patients-a multicenter pilot analysis","volume":"11","author":"Setoyama","year":"2016","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.jpsychires.2017.09.014_bib57","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.cmet.2007.08.003","article-title":"Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle","volume":"6","author":"She","year":"2007","journal-title":"Cell Metab."},{"issue":"59 Suppl","key":"10.1016\/j.jpsychires.2017.09.014_bib58","first-page":"22","article-title":"The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10","volume":"20","author":"Sheehan","year":"1998","journal-title":"J.\u00a0Clin. Psychiatry"},{"issue":"1","key":"10.1016\/j.jpsychires.2017.09.014_bib59","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.psychres.2006.07.004","article-title":"The new GRID Hamilton Rating Scale for Depression demonstrates excellent inter-rater reliability for inexperienced and experienced raters before and after training","volume":"153","author":"Tabuse","year":"2007","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.jpsychires.2017.09.014_bib60","doi-asserted-by":"crossref","first-page":"15994","DOI":"10.1038\/srep15994","article-title":"(13)C-tryptophan breath test detects increased catabolic turnover of tryptophan along the kynurenine pathway in patients with major depressive disorder","volume":"5","author":"Teraishi","year":"2015","journal-title":"Sci. Rep."},{"issue":"5","key":"10.1016\/j.jpsychires.2017.09.014_bib61","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/cns.12372","article-title":"Plasma amino acid profiling in major depressive disorder treated with selective serotonin reuptake inhibitors","volume":"21","author":"Woo","year":"2015","journal-title":"CNS Neurosci. Ther."},{"issue":"2\u20133","key":"10.1016\/j.jpsychires.2017.09.014_bib62","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/j.psychres.2012.05.027","article-title":"Potential clinical utility of plasma amino acid profiling in the detection of major depressive disorder","volume":"200","author":"Xu","year":"2012","journal-title":"Psychiatry Res."},{"issue":"3","key":"10.1016\/j.jpsychires.2017.09.014_bib63","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1007\/s11306-012-0474-9","article-title":"Peripheral metabolic abnormalities of lipids and amino acids implicated in increased risk of suicidal behavior in major depressive disorder","volume":"9","author":"Zheng","year":"2013","journal-title":"Metabolomics"},{"issue":"3","key":"10.1016\/j.jpsychires.2017.09.014_bib64","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1021\/pr2010082","article-title":"Plasma metabonomics as a novel diagnostic approach for major depressive disorder","volume":"11","author":"Zheng","year":"2012","journal-title":"J.\u00a0Proteome Res."},{"issue":"2","key":"10.1016\/j.jpsychires.2017.09.014_bib65","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.jad.2013.04.028","article-title":"Severity classification on the Hamilton depression rating scale","volume":"150","author":"Zimmerman","year":"2013","journal-title":"J.\u00a0Affect Disord."}],"container-title":["Journal of Psychiatric Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395617305344?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022395617305344?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T01:29:14Z","timestamp":1656034154000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022395617305344"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":65,"alternative-id":["S0022395617305344"],"URL":"https:\/\/doi.org\/10.1016\/j.jpsychires.2017.09.014","relation":{},"ISSN":["0022-3956"],"issn-type":[{"value":"0022-3956","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Plasma amino acid profile in major depressive disorder: Analyses in two independent case-control sample sets","name":"articletitle","label":"Article Title"},{"value":"Journal of Psychiatric Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpsychires.2017.09.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}